Quality of Life

Spirituality is Associated with Reduced Emotional Distress in Lung Cancer Survivors

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Spirituality is Associated with Reduced Emotional Distress in Lung Cancer Survivors

 

By John M. de Castro, Ph.D.

 

“However you define spirituality, studies show that it can play an important role in coping with the recovery and healing process from cancer treatment and its after effects.” – LungCancer.org

 

Receiving a diagnosis of cancer has a huge impact on most people. Feelings of depression, anxiety, and fear are very common and are normal responses to this life-changing and potentially life-ending experience. These feeling can result from changes in body image, changes to family and work roles, feelings of grief at these losses, and physical symptoms such as pain, nausea, or fatigue. People might also fear death, suffering, pain, or all the unknown things that lie ahead. So, coping with the emotional distress and stress of a cancer diagnosis is a challenge and there are no simple treatments for these psychological sequelae of cancer diagnosis.

 

Religion and spirituality become much more important to people when they’re diagnosed with cancer or when living with cancer. It is thought that people take comfort in the spiritual when facing mortality. Hence, spirituality may be a useful tool for the survivors of cancer to cope with their illness and the consequent emotional distress. Thus, it makes sense to study the relationships of spirituality with the mental health of cancer survivors.

 

In today’s Research News article “Spirituality and Emotional Distress Among Lung Cancer Survivors.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859202/ ) Gudenkauf and colleagues recruited adult patients with lung cancer and had them complete questionnaires measuring spirituality, emotional distress, and quality of life. within 1 year of their diagnosis and 1 year later.

 

They found that the lung cancer survivors, not surprisingly, were generally high in emotional distress. But those survivors who were high in spirituality, including the meaning, peace, and faith dimensions, were high in quality of life and low in emotional distress. In addition, those survivors who were high in distress at the first measurement, if they were also high in spirituality meaning, were more likely to have low emotional distress 1 year later.

 

It should be kept in mind that the present study was observational and as a result causation cannot be determined. But it appears that in these lung cancer survivors, spirituality is associated with better quality of life and lower emotional distress and that spirituality tends to predict lower emotional distress a year later. Hence, spirituality appears to help survivors cope with their emotional reactions to their diagnosis. Future studies should investigate whether promoting spirituality in these survivors may improve their emotions and quality of life.

 

So, spirituality is associated with reduced emotional distress in lung cancer survivors.

 

“While having a spiritual or religious foundation can’t change your diagnosis or the effectiveness of treatment, some patients find their beliefs help them find meaning and cope. “It may not impact your prognosis, but it can help improve your overall outlook during treatment,” – Tiffany Meyer

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Gudenkauf, L. M., Clark, M. M., Novotny, P. J., Piderman, K. M., Ehlers, S. L., Patten, C. A., Nes, L. S., Ruddy, K. J., Sloan, J. A., & Yang, P. (2019). Spirituality and Emotional Distress Among Lung Cancer Survivors. Clinical lung cancer, 20(6), e661–e666. https://doi.org/10.1016/j.cllc.2019.06.015

 

Abstract

Background:

Emerging research is highlighting the importance of spirituality in cancer survivorship as well as the importance of early distress screening. The purpose of this study was to prospectively examine the relationships among spirituality, emotional distress, and sociodemographic variables during the early period of lung cancer survivorship.

Patients and Methods:

864 lung cancer survivors completed the Functional Assessment of Chronic Illness Therapy – Spiritual Well-Being (FACIT-Sp), and the Short-Form-8 (SF-8) for emotional distress within the first year following lung cancer diagnosis, and 474 of these survivors completed the survey again one year later.

Results:

At baseline, spirituality was associated with lower prevalence of emotional distress, being married, fewer years of cigarette smoking, and better ECOG performance status. Additionally, high baseline spirituality was associated with lower rates of high emotional distress at one-year follow-up.

Conclusion:

These findings suggest that spirituality may serve as a protective factor for emotional distress among lung cancer survivors. Further research is warranted to explore the role of spirituality in promoting distress management among lung cancer survivors.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859202/

 

Cancer Patients’ Quality of Life is Associated with Mindfulness

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Cancer Patients’ Quality of Life is Associated with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness-based intervention . . . may help to decrease the stress of cancer-related cognitive impairment and can therefore indirectly improve quality of life in this patient population.” – Hannah Slater

 

Receiving a diagnosis of cancer has a huge impact on most people. Feelings of depression, anxiety, and fear are very common and are normal responses to this life-changing and potentially life-ending experience. But cancer diagnosis is not necessarily a death sentence. Over half of the people diagnosed with cancer are still alive 10 years later and this number is rapidly increasing. But, surviving cancer carries with it a number of problems. Anxiety, depression, fatigue and insomnia are common symptoms in the aftermath of surviving breast cancer. These symptoms markedly reduce the quality of life of the patients. Mindfulness training has been shown to help with cancer recovery and help to relieve chronic pain. It can also help treat the residual physical and psychological symptoms, including stress, sleep disturbance, fear, and anxiety and depression.

 

In today’s Research News article “Stress and Quality of Life of Patients with Cancer: The Mediating Role of Mindfulness.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748895/ ) Dehghan and colleagues recruited adult patients diagnosed with cancer and had them complete measures of mindfulness, perceived stress, and quality-of-life; including overall, functioning, and symptoms. They performed regression and path analysis on these data.

 

They found that the higher the level of mindfulness, the higher the level of quality-of-life functioning and the lower the level of perceived stress and quality of life symptoms. Also, the higher the level of perceived stress the higher the level of quality-of-life symptoms and the lower the level of overall and functioning quality of life. They reported from the path analysis that perceived stress was associated with poorer quality of life directly and indirectly by being associated with lower levels of mindfulness which were in turn associated with greater quality of life. In other words, perceived stress was associated with reduced quality of life in part by being associated with reduced mindfulness.

 

These results are correlative and causation cannot be determined. But prior manipulative research has demonstrated that mindfulness produces lower perceived stress and greater quality of life, So, the associations reported here are likely due to causal connections between the variables. Hence, the findings suggest that the quality of life of cancer patients is lowered by stress and this is in part due to stress lowering mindfulness.

 

So, cancer patients’ quality of life is associated with mindfulness.

 

“Mindfulness based interventions hold a great deal of promise for helping people with cancer cope across a broad range of symptoms and issues, both during and after the completion of active treatment.” – Jessica Pieczynski

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Dehghan, M., Jazinizade, M., Malakoutikhah, A., Madadimahani, A., Iranmanesh, M. H., Oghabian, S., Mohammadshahi, F., Janfaza, F., & Zakeri, M. A. (2020). Stress and Quality of Life of Patients with Cancer: The Mediating Role of Mindfulness. Journal of Oncology, 2020, 3289521. https://doi.org/10.1155/2020/3289521

 

Abstract

Background

Cancer is one of the major health problems worldwide, which in addition to physical disorders, causes stress and anxiety in patients and affects the quality of life of cancer patients. Mindfulness can affect stress and improve the quality of life. This research explained the correlation between stress, quality of life, and mindfulness.

Materials and Methods

Two hundred five cancer patients participated in this cross-sectional study. Patients completed the EORTC Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), the Mindfulness Attention and Awareness Scale (MAAS), and Perceived Stress Scale (PSS).

Results

Perceived stress and mindfulness predict nearly 39% of the changes of QOL in cancer patients. In addition, perceived stress was negatively associated with mindfulness and quality of life (P < 0.05). Mindfulness was positively correlated with quality of life (P < 0.05). Mindfulness played a mediating role in the relationship between perceived stress and quality of life (standardized β = −0.13; SE = 0.07, 95% confidence interval = −0.28 to −0.01; P value = 0.04).

Conclusion

In the present study, the variables of mindfulness and perceived stress affected the quality of life of cancer patients. Mindfulness can affect the quality of life of cancer patients directly and indirectly. These results emphasize the importance of mindfulness in the lives of cancer patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748895/

 

Improve Psychological Health and Quality of Life of Older Adults with Meditative Movement Practices.

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Improve Psychological Health and Quality of Life of Older Adults with Meditative Movement Practices.

 

By John M. de Castro, Ph.D.

 

“Mindful techniques can help older adults feel a sense of connection to their body. This can be critical for creating optimal health, even as they manage the ongoing changes in their body.” – Karen Fabian

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. This includes our cognitive (mental) abilities which decline with age including impairments in memory, attention, and problem-solving ability. It is inevitable and cannot be avoided. Research has found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation and yoga have been found to degenerate less with aging than non-practitioners. Tai Chi and Qigong have also been shown to be beneficial in slowing or delaying physical and mental decline with aging. The research findings are accumulating suggesting that a summarization of what has been learned is called for.

 

In today’s Research News article “Effects of Mind-Body Interventions Involving Meditative Movements on Quality of Life, Depressive Symptoms, Fear of Falling and Sleep Quality in Older Adults: A Systematic Review with Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559727/ ) Weber and colleagues  review, summarize, and perform a meta-analysis of the published randomized controlled studies (RCTs) of the effectiveness of the mind-body practices of Yoga, Tai Chi. Qigong, and Pilates to improve the psychological health and quality of life in the elderly (aged 60 and over). They identified 37 published RCTs, 21 of which employed Tai Chi. 5 Qigong, 10 Yoga, and 3 Pilates.

 

They separated studies employing Tai Chi and Qigong from those employing Yoga and Pilates. They report that the published studies found that all of the meditative movement practices significantly improved the quality of life, physical functioning, and sleep quality and reduced the fear of falling of older adults with small effect sizes. Only the Tai Chi and Qigong practices produced significant improvements in psychological functioning and social functioning while only the Yoga and Pilates produced significant improvements in depression. For Tai Chi and Qigong, they further report that practice occurring 3 or more times per week resulted in larger improvements in quality of life and depression than those with less than 3 practices per week.

 

These findings suggest that meditative movement practices have wide ranging benefits, albeit with relatively small effect sizes, on the physical, psychological, and social functioning of older adults and improve their overall quality of life. These are important benefits for the elderly helping to slow the progressive decline seen with aging. These practices when properly performed and supervised have very few adverse effects. Hence, they should be recommended for aging individuals as safe and effective practices to slow the progressive decline and improve their overall well-being.

 

So, improve psychological health and quality of life of older adults with meditative movement practices.

 

“When you age mindfully, you are fully aware and accepting of the challenges that come with the aging process, but you’re also aware of—and seizing—the opportunities that come with being blessed with what I call your ‘longevity bonus,’” – Andrea Brandt.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Weber, M., Schnorr, T., Morat, M., Morat, T., & Donath, L. (2020). Effects of Mind-Body Interventions Involving Meditative Movements on Quality of Life, Depressive Symptoms, Fear of Falling and Sleep Quality in Older Adults: A Systematic Review with Meta-Analysis. International journal of environmental research and public health, 17(18), 6556. https://doi.org/10.3390/ijerph17186556

 

Abstract

Background: The aim of the present systematic meta-analytical review was to quantify the effects of different mind–body interventions (MBI) involving meditative movements on relevant psychological health outcomes (i.e., quality of life (QoL), depressive symptoms, fear of falling (FoF) and sleep quality) in older adults without mental disorders. Methods: A structured literature search was conducted in five databases (Ovid, PsycINFO, PubMed, SPORTDiscus, Web of Science). Inclusion criteria were: (i) the study was a (cluster) randomized controlled trial, (ii) the subjects were aged ≥59 years without mental illnesses, (iii) an intervention arm performing MBI compared to a non-exercise control group (e.g., wait-list or usual care), (iv) psychological health outcomes related to QoL, depressive symptoms, FoF or sleep quality were assessed and (v) a PEDro score of ≥5. The interventions of the included studies were sub-grouped into Tai Chi/Qigong (TCQ) and Yoga/Pilates (YP). Statistical analyses were conducted using a random-effects inverse-variance model. Results: Thirty-seven randomized controlled trials (RCTs) (comprising 3224 participants) were included. Small to moderate-but-significant overall effect sizes favoring experimental groups (Hedges’ g: 0.25 to 0.71) compared to non-exercise control groups were observed in all outcomes (all p values ≤ 0.007), apart from one subdomain of quality of life (i.e., social functioning, p = 0.15). Interestingly, a significant larger effect on QoL and depressive symptoms with increasing training frequency was found for TCQ (p = 0.03; p = 0.004). Conclusions: MBI involving meditative movements may serve as a promising opportunity to improve psychological health domains such as QoL, depressive symptoms, FoF and sleep quality in older adults. Hence, these forms of exercise may represent potential preventive measures regarding the increase of late-life mental disorders, which need to be further confirmed by future research.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559727/

 

Reduce Fatigue and Improve Quality of Life of Breast Cancer Survivors with Yoga

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Reduce Fatigue and Improve Quality of Life of Breast Cancer Survivors with Yoga

 

By John M. de Castro, Ph.D.

 

“For women with breast cancer, research shows those who practice yoga may also have less stress and fatigue, and better quality of life.” – Stacie Simon

 

Because of great advances in treatment, many patients today are surviving cancer. But cancer survivors frequently suffer from anxiety, depression, mood disturbance, post-traumatic stress disorder (PTSD), sleep disturbance, fatigue, sexual dysfunction, loss of personal control, impaired quality of life, and psychiatric symptoms which have been found to persist even ten years after remission. Also, cancer survivors can have to deal with a heightened fear of reoccurrence. So, safe and effective treatments for the symptoms in cancer and the physical and psychological effects of the treatments are needed.

 

Mindfulness training has been shown to help with general cancer recovery. Mindfulness practices have been shown to improve the residual symptoms in cancer survivors.  Yoga is both an exercise and a mindfulness practice that has also been shown to be helpful with the residual symptoms in cancer survivors, the psychological and physical ability to deal with cancer treatment and improves sleep. The research on yoga practice as a treatment for patients recovering from breast cancer has been accumulating. It is thus reasonable to take a step back and summarize what has been learned.

 

In today’s Research News article “The Effect of Yoga Interventions on Cancer-Related Fatigue and Quality of Life for Women with Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580184/ ) O’Neill and colleagues review, summarize, and perform a meta-analysis of published randomized controlled trials of the effects of yoga practice on the fatigue and quality of life of breast cancer survivors. They identified 24 published randomized controlled trials.

 

They report that the published trials revealed that yoga practice produced significant reductions in cancer related fatigue and increases in the women’s quality of life. This was true overall and for the 18 trials with a passive control group such as a wait-list control, but not for the 6 trials with an active control group, such as physical exercise or supportive therapy. Hence, yoga practice appears to be beneficial for breast cancer survivors reducing fatigue and improving quality of life. But the benefits are comparable to those produced by other exercises or therapies.

 

So, reduce fatigue and improve quality of life of breast cancer survivors with yoga.

 

“A targeted yoga intervention led to significant improvements in fatigue and vigor among breast cancer survivors with persistent fatigue symptoms.” – Julienne Bower

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

O’Neill, M., Samaroo, D., Lopez, C., Tomlinson, G., Santa Mina, D., Sabiston, C., Culos-Reed, N., & Alibhai, S. (2020). The Effect of Yoga Interventions on Cancer-Related Fatigue and Quality of Life for Women with Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Integrative cancer therapies, 19, 1534735420959882. https://doi.org/10.1177/1534735420959882

 

Abstract

Background:

Women with breast cancer (BC) are living longer with debilitating side effects such as cancer-related fatigue (CRF) that affect overall well-being. Yoga promotes health, well-being and may be beneficial in reducing CRF. Although there have been previous systematic reviews and meta-analyses, the effects of yoga on CRF and quality of life (QOL) remain unclear, particularly in comparison with other types of physical activity (PA). Our objective is to carry out a systematic review and meta-analysis of the effects of yoga on CRF and QOL in women with BC.

Methods:

Electronic databases were searched (MEDLINE, Embase Classic+Embase and EMB Reviews, Cochrane Central CT) from inception to May 2018. Randomized controlled trials were included if they were full text, in English, included a yoga intervention, a comparator (including non-PA usual care or alternate PA intervention), and reported on CRF or QOL. Effects of yoga were pooled using standardized mean difference (SMD) via a random effects model.

Results:

Of the 2468 records retrieved, 24 trials were included; 18 studies compared yoga to a non-PA comparator and 6 to a PA comparator. Yoga demonstrated statistically significant improvements in CRF over non-PA (SMD −0.30 [−0.51; −0.08]) but not PA (SMD −0.17 [−0.50; 0.17]) comparators. Additionally, yoga demonstrated statistically significant improvements in QOL over non-PA (SMD −0.27 [−0.46; −0.07]) but not PA (SMD 0.04 [−0.22; +0.31]) comparators.

Discussion:

This meta-analysis found that yoga provides small to medium improvements in CRF and QOL compared to non-PA, but not in comparison to other PA interventions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580184/

 

Reduce Anxiety in Women Undergoing Fertility Treatment with Yoga

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Reduce Anxiety in Women Undergoing Fertility Treatment with Yoga

 

By John M. de Castro, Ph.D.

 

“yoga is a relaxing activity. And there are some researched benefits regarding yoga, infertility, and the exercise’s ability to help couples release mental stress and physical tension.” – Ashley Marcin

 

Infertility is primarily a medical condition due to physiological problems. It is quite common. It is estimated that in the U.S. 6.7 million women, about 10% of the population of women 15-44, have an impaired ability to get pregnant or carry a baby to term and about 6% are infertile. Infertility can be more than just a medical issue. It can be an emotional crisis for many couples, especially for the women. Couples attending a fertility clinic reported that infertility was the most upsetting experience of their lives.

 

Women with infertility reported feeling as anxious or depressed as those diagnosed with cancer, hypertension, or recovering from a heart attack. In addition, infertility can markedly impact the couple’s relationship, straining their emotional connection and interactions and the prescribed treatments can take the spontaneity and joy from lovemaking making it strained and mechanical. The stress of infertility and engaging in infertility treatments may exacerbate the problem. Since mindfulness training has been shown to reduce depression, anxiety, and stress it is reasonable to believe that mind-body training may be helpful in reducing the distress in women with fertility issues. Yoga is both a mindfulness practice and an exercise that has been studied for its benefits for women undergoing fertility treatments.

 

In today’s Research News article “Effect of Yoga on Psychological Distress among Women Receiving Treatment for Infertility.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336944/ ) Dumbala and colleagues review and summarize the published research studies on the effectiveness of yoga practice for the relief of the psychological symptoms produced by infertility.

 

They identified 3 published research studies all of which found that yoga practice reduced anxiety levels in women being treated for infertility. They also report that the research found that yoga improved the quality of life and reduced depression levels in these women. It has previously been shown that yoga practice reduces anxiety and depression and improves quality of life in a wide variety of healthy and ill individuals. The present review demonstrates that these benefits also extend to women being treated for infertility. The review and the included studies did not study whether yoga increased the likelihood of conception. But improving the psychological state of these women could only be helpful.

 

So, reduce anxiety in women undergoing fertility treatment with yoga.

 

“Yoga also offers a safe space for us to work through challenge and build resilience. It allows us to sit with discomfort by challenging us to hold a pose longer than we’d like, knowing it’s temporary. This is a valuable skill, not only for the fertility process, but it also helps prepare us for birth and parenthood (which combine discomfort, joy, and everything in between!)” – Kate Potvin

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Dumbala, S., Bhargav, H., Satyanarayana, V., Arasappa, R., Varambally, S., Desai, G., & Bangalore, G. N. (2020). Effect of Yoga on Psychological Distress among Women Receiving Treatment for Infertility. International journal of yoga, 13(2), 115–119. https://doi.org/10.4103/ijoy.IJOY_34_19

 

Abstract

Background:

Infertility among women has been associated with significant psychological distress, anxiety, and depression. yoga therapy has been found to be useful in the management of anxiety, depression and psychological distress.

Aim:

To review studies on the effectiveness of yoga in reducing psychological distress and improving clinical outcomes among women receiving treatment for infertility.

Methodology:

PubMed, ScienceDirect, and Google Scholar databases were searched for studies using the following inclusion criteria: studies published in English, those published between 2000 and 2018, published in peer-reviewed journals, and those with Yoga as an intervention. Review articles, studies without any yoga interventions for infertility, and male infertility were excluded. The keywords included for the literature search were: Yoga, Mindfulness, Relaxation technique, Stress, Distress, Anxiety, Infertility, In Vitro Fertilization (IVF), and Assisted Reproductive Technology (ART).

Results:

Three studies satisfied the selection criteria. Two studies involved Hatha yoga intervention and one study used structured yoga program. The variables assessed in these studies were: (1) anxiety, (2) depression, (3) emotional distress, and (4) fertility-related quality of life. All the studies reported an improvement in the anxiety scores after yoga intervention.

Conclusion:

Yoga therapy may be potentially useful in improving anxiety scores among women suffering from infertility. More studies are needed in this area to establish role of yoga as an adjuvant during the treatment of infertility.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336944/

 

Manage Symptoms in Cancer Survivors with Yoga

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Manage Symptoms in Cancer Survivors with Yoga

 

By John M. de Castro, Ph.D.

 

“when it’s used alongside conventional medical treatment, yoga may help relieve some of the symptoms linked to cancer.” – American Cancer Society

 

Because of great advances in treatment, many patients today are surviving cancer. But cancer survivors frequently suffer from anxiety, depression, mood disturbance, post-traumatic stress disorder (PTSD), sleep disturbance, fatigue, sexual dysfunction, loss of personal control, impaired quality of life, and psychiatric symptoms which have been found to persist even ten years after remission. Also, cancer survivors can have to deal with a heightened fear of reoccurrence. This is particularly true with metastatic cancer. So, safe and effective treatments for the symptoms in cancer and the physical and psychological effects of the treatments are needed.

 

Mindfulness training has been shown to help with general cancer recovery . Yoga is both an exercise and a mindfulness practice that has also been shown to be helpful with the residual symptoms in cancer survivors, the psychological and physical ability to deal with cancer treatment and improves sleep. So, it’s reasonable to review what has been learned about the benefits of yoga practice to improve the residual symptoms of patients who have survived cancer.

 

In today’s Research News article “Yoga for symptom management in oncology: A review of the evidence base and future directions for research.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541520/ ) Danhauer and colleagues review and summarize the published randomized controlled studies of the effectiveness of yoga practice for the treatment of the symptoms of cancer survivors. They identified 29 published randomized controlled trials, 13 conducted during treatment, 12 after treatment, and 4 both before and after.

 

They report that the published research found that yoga during treatment for cancer significantly improved the patient’s quality of life, including physical, emotional social, and cognitive quality of life. They also report that yoga significantly reduced fatigue, distress, perceived stress, and biomarkers of stress and inflammation. Yoga after treatment completion was found to significantly reduce fatigue and sleep disturbance and improve quality of life. There were no serious adverse events resulting from yoga practice reported.

 

The published research then suggests that yoga practice is a safe and effective treatment both during and after cancer treatment for the relief of the patients’ residual physical and psychological symptoms. Yoga practice is a complex of practices that includes postures, breath control, and meditation. It has not been clearly established which of these components or which combination of components are required for the benefits. So, conclusions cannot be made regarding mechanisms of action by which yoga produces its benefits. But it can be concluded that yoga practice is very beneficial for cancer sufferers.

 

So, manage symptoms in cancer survivors with yoga.

 

“yoga can combat fatigue and improve strength and range of motion for patients undergoing cancer treatment,” – Dr. Maggie DiNome

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are a also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Danhauer, S. C., Addington, E. L., Cohen, L., Sohl, S. J., Van Puymbroeck, M., Albinati, N. K., & Culos-Reed, S. N. (2019). Yoga for symptom management in oncology: A review of the evidence base and future directions for research. Cancer, 125(12), 1979–1989. https://doi.org/10.1002/cncr.31979

 

Abstract

As yoga is increasingly recognized as a complementary approach to cancer symptom management, patients/survivors and providers need to understand its potential benefits and limitations both during and after treatment. We reviewed randomized controlled trials (RCTs) of yoga conducted at these points in the cancer continuum (N=29; n=13 during treatment, n=12 post-treatment, n=4 with mixed samples). Findings both during and after treatment demonstrated efficacy of yoga to improve overall quality of life (QOL), with improvement in subdomains of QOL varying across studies. Fatigue was the most commonly measured outcome, and most RCTs conducted during or after cancer treatment reported improvements in fatigue. Results additionally suggest that yoga can improve stress/distress during treatment and post-treatment disturbances in sleep and cognition. A number of RCTs showed evidence that yoga may improve biomarkers of stress, inflammation, and immune function. Outcomes with limited or mixed findings (e.g., anxiety, depression, pain, cancer-specific symptoms such as lymphedema, positive psychological outcomes such as benefit-finding and life satisfaction) warrant further study. Important future directions for yoga research in oncology include: enrolling participants with cancer types other than breast, standardizing self-report assessments, increasing use of active control groups and objective measures, and addressing the heterogeneity of yoga interventions, which vary in type, key components (movement, meditation, breathing), dose, and delivery mode.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541520/

 

Improve the Quality of Life with Aging with Tai Chi

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Improve the Quality of Life with Aging with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Over the past few years, tai chi has been at the top of the list of “alternative therapies” with benefits that . . . helps senior improve their balance, mood and joint health.” – IlluminAge

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. This markedly reduces the quality of life in aging individuals. There is some hope for age related decline, however, as there is evidence that it can be slowed. There are some indications that physical and mental exercise can reduce the rate of decline. For example, contemplative practices such as meditation, yoga, and Tai Chi or qigong have all been shown to be beneficial in slowing or delaying physical and mental decline with aging. The research findings have been accumulating. So, it makes sense to step back and summarize what has been learned about the effectiveness of Tai Chi for reducing the decline in quality of life during aging.

 

In today’s Research News article “Effectiveness of Tai chi exercise on overall quality of life and its physical and psychological components among older adults: a systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485323/ ) Wang and colleagues review, summarize, and perform a meta-analysis of the published research studies of the effectiveness of Tai Chi practice in reducing the age related decline in quality of life. They identified 10 published randomized controlled trials with a total of 1170 participants who were aged 50 years and older.

 

They report that the published research found that Tai Chi practice significantly improved the quality of life in older and elderly individuals. This improvement was significant particularly for physical component of quality of life. But was not significant for the psychological component. This is not surprising as Tai Chi practice has been shown to improve strength and balance and reduce the likelihood of falls in older individuals. These benefits should improve their physical well being and reduce the likelihood of injury.

 

It is a bit surprising that the psychological component of quality of life was not improved. Tai Chi is often practiced in social groups while the elderly are often isolated and have high levels of loneliness. So, it would be expected that the social interactions occurring with Tai Chi practice would improve their psychological well-being. This needs to be further researched.

 

Tai Chi is an ancient mindfulness practices involving slow prescribed movements. It is gentle and completely safe, can be used with the healthy and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. This makes Tai Chi an almost ideal practice for the improvement of quality of life in aging individuals.

 

So, improve the quality of life with aging with Tai Chi.

 

”Tai Chi promotes optimal aging and well-being by providing mild-to-moderate cardiorespiratory exercise, muscular strengthening, balance and postural control along with many mental and social benefits.” – Kristine Hallisy

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wang, D., Wang, P., Lan, K., Zhang, Y., & Pan, Y. (2020). Effectiveness of Tai chi exercise on overall quality of life and its physical and psychological components among older adults: a systematic review and meta-analysis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 53(10), e10196. https://doi.org/10.1590/1414-431X202010196

 

Abstract

With the aging of the world’s population, the quality of life of older adults is becoming more important. There are many studies on the use of Tai chi exercise, a popular form of mind-body exercise practiced by older adults. However, the effectiveness of Tai chi exercise on the quality of life of older adults is unclear. For this systematic review and meta-analysis, six databases (PubMed, CENTRAL, CINAHL, EMBASE, Scopus, CNKI) were searched in English and Chinese languages to screen for relevant randomized controlled trials (RCT), and their risk of bias was assessed by two independent reviewers. The results of quality of life, physical component, and psychological component among older adults were meta-analyzed using RevMan5.3 software. The search retrieved 2577 records. After screening, a total of 10 RCTs were included in this evaluation, with a total of 1170 participants. The meta-analysis showed that compared with the control group, Tai chi exercise had a significant impact on the overall quality of life (SMD=1.23; 95%CI: 0.56–1.98; P<0.0001), and on the physical component of quality of life (MD=5.90; 95%CI: 1.05–10.75; P=0.02), but no significant impact on the psychological component of quality of life. This study had high heterogeneity. The results of this study suggest the potential use of Tai chi exercise as an activity for increased quality of life in older adults. Future research may enhance experimental rigor and explore the rationale behind Tai chi exercise.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485323/

 

Reduce Inflammatory Responses and Reduce Rheumatoid Arthritis Symptoms with Yoga

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Reduce Inflammatory Responses and Reduce Rheumatoid Arthritis Symptoms with Yoga

 

By John M. de Castro, Ph.D.

 

“yoga practice significantly decreases the severity of physical and psychological symptoms in patients with active rheumatoid arthritis.” – Science Daily

 

Arthritis is a chronic disease that most commonly affects the joints. Depending on the type of arthritis, symptoms may include pain, stiffness, swelling, redness, and decreased range of motion. It affects an estimated 52.5 million adults in the United States. It is associated with aging as arthritis occurs in only 7% of adults ages 18–44, while 30% adults ages 45–64 are affected, and 50% of adults ages 65 or older. Due to complications associated with rheumatoid arthritis (RA), the lifespan for people with RA may be shortened by 10 years. This is due to a higher incidence of cardiovascular disease in rheumatoid arthritis (RA) patients, with the risk more than double that of non-RA individuals.

 

Obviously, there is a need to explore alternative treatments for rheumatoid arthritis. One possibility is contemplative practice. A variety of which have been shown to have major mental and physical benefits including a reduction in the inflammatory response and have been shown to improve arthritis. Indeed, yoga practice has been shown to be effective in treating arthritis. So, it makes sense to investigate the effects of yoga practice on the inflammatory response in patients with rheumatoid arthritis.

 

In today’s Research News article “Effect of an 8-Week Yoga-Based Lifestyle Intervention on Psycho-Neuro-Immune Axis, Disease Activity, and Perceived Quality of Life in Rheumatoid Arthritis Patients: A Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492675/ ) Gautam and colleagues recruited adult patients with rheumatoid arthritis and continued with their usual care. They were randomly assigned to either no-treatment or ashtanga yoga practice modified for patients with rheumatoid arthritis. They practiced 5 times per week for 2 hours for 8 weeks. The practice included postures, breathing exercises, meditation, relaxation, and personal lifestyle management. They were measured before and after training for disease activity and quality of life. They also had blood drawn and assayed for biochemical markers of inflammation.

 

They found that in comparison to baseline and the no-treatment group, the yoga group had a significant decrease in rheumatoid arthritis disease activity and a significant increase in their psychological and social quality of life, with greater effects occurring in women than in men. In addition, they found that yoga practice decreased the gene expressions of and levels of pro-inflammatory biochemical markers IL-6, TNF-α, and CTLA4, and a significant increase in TGF-β, an anti-inflammatory marker, suggesting reduced inflammation in the yoga group.

 

This study did not have an active control condition or a long-term follow-up and as such the results must be interpreted with caution. Future studies should include long-term follow-up and an active control condition such as aerobic exercise to determine if the results were due to exercise in general or specifically to yoga practice and whether the benefits were lasting. Nevertheless, the results replicate the findings of other research that yoga practice improves arthritis symptoms and reduces inflammatory responses. The results suggest that yoga practice reduces the inflammatory responses that promote the disease and thereby reduce the disease symptoms which in turn improves the patient’s quality of life. This is good news for these patients signaling that practicing yoga may help relieve their suffering and retard disease progression.

 

So, reduce inflammatory responses and reduce rheumatoid arthritis symptoms with yoga.

 

“People with various types of arthritis who practice yoga regularly can reduce joint pain, improve joint flexibility and function, and lower stress and tension to promote better sleep.“ – Susan Bernstein

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Gautam, S., Kumar, M., Kumar, U., & Dada, R. (2020). Effect of an 8-Week Yoga-Based Lifestyle Intervention on Psycho-Neuro-Immune Axis, Disease Activity, and Perceived Quality of Life in Rheumatoid Arthritis Patients: A Randomized Controlled Trial. Frontiers in Psychology, 11, 2259. https://doi.org/10.3389/fpsyg.2020.02259

 

Abstract

Various external stressors and environmental challenges lead to the provocation of the immune system in autoimmune diseases like Rheumatoid arthritis (RA). The inappropriate immune response further triggers the cascade of inflammatory changes resulting in precipitation of symptoms and hampers quality of life (QOL). The underlying psycho-somatic component of the disease requires a holistic approach to its treatment dimension rather than the use of pharmacotherapy. The applicability of mind-body interventions has become essential in today’s fast-paced life. Yoga, a mind-body technique, alters the mind’s capacity to facilitate systemic functioning at multiple organ system levels. Hence, we conducted this study to evaluate the impact of 8 weeks of a yoga-based lifestyle intervention (YBLI) on psycho-neuro-immune markers, gene expression patterns, and QOL in RA patients on routine medical therapy. A total of 66 patients were randomized into two groups: yoga group or non-yoga group and were assessed for a panel of inflammatory cytokines (IL-6, IL-17A, TNF-α, and TGF-β), mind-body communicative markers (BDNF, DHEAS, β-endorphin, and sirtuin) and transcript levels of various genes (IL-6, TNF-α, NFKB1, TGF-β, and CTLA4). We assessed disease activity and QOL using the DAS28-ESR and WHOQOL-BREF questionnaire, respectively. Yoga group observed significant improvements in the levels of markers, which influenced the psycho-neuro-immune axis (p < 0.001) with an estimated effect size from small to medium range. In the yoga group, there was a significant reduction in DAS28-ESR (p < 0.001) and improvement seen in the physical health, psychological, social relationships domains (p < 0.001) of QOL, except environmental (p > 0.05). The yoga group showed downregulation of IL-6, TNF-α, and CTLA4 and upregulation of TGF-β. These results suggest that a decrease in disease activity after yoga practice is associated with a significant reduction in inflammatory cytokines, the elevation of mind-body communicative markers, and normalization of various transcript levels, which improved QOL. Thus the adoption of YBLI improves clinical outcome in RA, and decreases systemic inflammation by its beneficial effects on psycho-neuro-immune axis and normalization of dysregulated transcripts. Thus YBLI may be used for RA patients as an adjunctive therapy.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492675/

 

Yoga is the Preferred Exercise for the Treatment of Type 2 Diabetes

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Yoga is the Preferred Exercise for the Treatment of Type 2 Diabetes

 

By John M. de Castro, Ph.D.

 

“By increasing muscle mass through strengthening poses, yoga can improve your metabolism, helping you maintain a healthy body weight. Studies suggest that regular practice helps normalize blood pressure and cholesterol levels. By inducing a feeling of calm, yoga can lower the release of cortisol, a stress hor­mone that causes your body to release more glucose. Less unnecessary cortisol means fewer unnecessary elevations in blood sugar.” – Annie Kay

 

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes and the numbers are growing. Type II Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

 

Type 2 diabetes is a common and increasingly prevalent illness that is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary life style. Unlike Type I Diabetes, Type II does not require insulin injections. Instead, the treatment and prevention of Type 2 Diabetes focuses on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. A mindfulness practice that combines mindfulness with exercise is yoga and it has been shown to be helpful in the treatment of Type II Diabetes.

 

In today’s Research News article “Effect of Yoga and Exercise on Glycemic Control and Psychosocial Parameters in Type 2 Diabetes Mellitus: A Randomized Controlled Study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336951/ ) Singh and Khandelwal recruited adult patients with Type 2 Diabetes and randomly assigned them to either an exercise or yoga practice group. Exercise was practiced for 30 minutes 5 days per week for 3 months and consisted of walking and moderate aerobic exercise combined with diet. The yoga group were trained in postures and breathing exercises for 2 weeks and then practiced at home for 3 months. They were measured before and after training for anxiety, depression, diabetes quality of life and self-efficacy. They also had blood drawn for assessment of glycemic control (HbA1c).

 

They found that following training both groups had significant decreases in anxiety, depression, and HbA1c and significant increases in diabetes quality of life and self-efficacy. But the yoga group had significantly better outcomes on all measures compared to the diet and exercise group.

 

These results suggest that practicing yoga is better for the psychological and physical health of patients with Type 2 Diabetes than non-yoga exercises. Yoga practice not only improved psychological health but also glycemic control suggesting better control of the disease. The fact that yoga was superior in effectiveness to non-yoga exercise is important as yoga is both a mindfulness practice and an exercise. So, the results suggest that adding mindfulness to exercise potentiates the programs effectiveness in treating patients with Type 2 Diabetes.

 

Hence, yoga is the preferred exercise for the treatment of Type 2 Diabetes.

 

“I recommend yoga primarily for stress management. Stress elevates blood sugar, which can lead to more diabetes complications. Yoga helps us center ourselves, and centering calms us and can help keep blood sugar levels balanced.” – Janet Zappe

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

Vijay Pratap Singh, Bidita Khandelwal. Effect of Yoga and Exercise on Glycemic Control and Psychosocial Parameters in Type 2 Diabetes Mellitus: A Randomized Controlled Study. Int J Yoga. 2020 May-Aug; 13(2): 144–151. Published online 2020 May 1. doi: 10.4103/ijoy.IJOY_45_19

 

Abstract

Context (Background):

Type 2 diabetes has been strongly associated with psychosocial factors such as stress, anxiety, depression, and quality of life (QOL). There is not much evidence whether yoga can improve these factors and motivate individuals to engage in active lifestyle.

Aims:

This study aims to evaluate the effect of yoga and exercise over glycemic control, anxiety, depression, exercise self-efficacy (ESE), and QOL after 3-month program.

Methods:

Two hundred and twenty-seven individuals were randomly allocated to yoga group (YG) and exercise group. YG practiced yoga for 2 weeks under supervision and then carried out practice at home for 3 months. The exercise group practiced 30 min of brisk walking for 5 days a week.

Results:

On comparison among the groups, in YG, there was a mean change of 0.47 in glycated hemoglobin which was greater than mean reduction of 0.28 in the exercise group with P < 0.05. State anxiety reduced by 7.8 and trait anxiety reduced by 4.4 in YG (P < 0.05) in 3 months as compared to nonsignificant reductions of 3 and 1 in mean of state and trait anxiety scores in the exercise group (P > 0.05). There was a statistically significant reduction in depression score in both the groups, 8.6 in yoga and 4.0 in exercise, which was greater in YG. ESE improved by 19.2 in YG (P < 0.05), whereas it improved only 2.2 in the exercise group (P > 0.05). QOL improved by 23.7 in YG and 3.0 in the exercise group which was nonsignificant in the exercise group as compared to YG.

Conclusions:

Yoga is superior to exercise alone as a lifestyle modification program in improving glycemic control, anxiety, depression, and QOL as well as ESE.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336951/

 

Reduce Anxiety and Depression in Cancer Patients with Mindfulness

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Reduce Anxiety and Depression in Cancer Patients with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Practicing mindfulness can assist with uncertainty about the future, depression, fear of recurrence and anxiety as well as mitigate physical symptoms such as fatigue, pain, and sleep disturbance.” – Erin Murphy-Wilczek

 

Receiving a diagnosis of cancer has a huge impact on most people. Feelings of depression, anxiety, and fear are very common and are normal responses to this life-changing and potentially life-ending experience. But cancer diagnosis is not necessarily a death sentence. Over half of the people diagnosed with cancer are still alive 10 years later and this number is rapidly increasing. But, surviving cancer carries with it a number of problems. Anxiety, depression, fatigue and insomnia are common symptoms in the aftermath of surviving breast cancer. These symptoms markedly reduce the quality of life of the patients.

 

Mindfulness training has been shown to help with cancer recovery and help to relieve chronic pain. It can also help treat the residual physical and psychological symptoms, including stress,  sleep disturbance, fear, and anxiety and depression. There has been considerable research conducted on the effectiveness of mindfulness practices in treating the psychological issues associated with cancer. So, it makes sense to step back and summarize what has been learned about the effectiveness of mindfulness in treating anxiety in cancer patients.

 

In today’s Research News article “Association of Mindfulness-Based Interventions With Anxiety Severity in Adults With Cancer: A Systematic Review and Meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414391/) Oberoi and colleagues review, summarize, and perform a meta-analysis of the published research on the effectiveness of mindfulness in reducing anxiety in adult cancer patients. They found 28 published trials. The most common forms of mindfulness treatment were Mindfulness-Based Stress Reduction (MBSR) (13 studies) and Mindfulness-Based Cognitive Therapy (MBCT) (6 studies).

 

They report that the published research found that mindfulness training reduced anxiety and depression and increased quality of life over the short and medium term (up to 6 months post-treatment) with moderate effect sizes. The reduction in anxiety and depression may be responsible for the improvement in the patients’ quality of life. But 2 trials had longer term follow up measures (over 6 months) and did not find significant reductions. The fact that the effects do not appear to last beyond 6 months suggests that continued mindfulness practice or periodic booster sessions may be needed.

 

Fighting cancer is very stressful and amplifies negative emotions like anxiety and depression. The stress produced by these emotions can in turn interfere with the body’s ability to fight the cancer. So, treating these negative emotional states may be very important not only for the individual’s mental health but also to their physical well-being. So, mindfulness training may be important to the overall health of the cancer patient by reducing anxiety and depression.

 

So, reduce anxiety and depression in cancer patients with mindfulness.

 

“In summary, results show promise for mindfulness-based interventions to treat common psychological problems such as anxiety, stress, and depression in cancer survivors and to improve overall quality of life.” – Linda Carlson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Oberoi, S., Yang, J., Woodgate, R. L., Niraula, S., Banerji, S., Israels, S. J., Altman, G., Beattie, S., Rabbani, R., Askin, N., Gupta, A., Sung, L., Abou-Setta, A. M., & Zarychanski, R. (2020). Association of Mindfulness-Based Interventions With Anxiety Severity in Adults With Cancer: A Systematic Review and Meta-analysis. JAMA network open, 3(8), e2012598. https://doi.org/10.1001/jamanetworkopen.2020.12598

 

Abstract

Importance

Mindfulness-based interventions (MBIs), grounded in mindfulness, focus on purposely paying attention to experiences occurring at the present moment without judgment. MBIs are increasingly used by patients with cancer for the reduction of anxiety, but it remains unclear if MBIs reduce anxiety in patients with cancer.

Objective

To evaluate the association of MBIs with reductions in the severity of anxiety in patients with cancer.

Data Sources

Systematic searches of MEDLINE, Embase, Cochrane Central Register of Controlled Trials, CINAHL, PsycINFO, and SCOPUS were conducted from database inception to May 2019 to identify relevant citations.

Study Selection

Randomized clinical trials (RCTs) that compared MBI with usual care, waitlist controls, or no intervention for the management of anxiety in cancer patients were included. Two reviewers conducted a blinded screening. Of 101 initially identified studies, 28 met the inclusion criteria.

Data Extraction and Synthesis

Two reviewers independently extracted the data. The Cochrane Collaboration risk-of-bias tool was used to assess the quality of RCTs, and the Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guideline was followed. Summary effect measures were reported as standardized mean differences (SMDs) and calculated using a random-effects model.

Main Outcomes and Measures

Our primary outcome was the measure of severity of short-term anxiety (up to 1-month postintervention); secondary outcomes were the severity of medium-term (1 to ≤6 months postintervention) and long-term (>6 to 12 months postintervention) anxiety, depression, and health-related quality of life of patients and caregivers.

Results

This meta-analysis included 28 RCTs enrolling 3053 adults with cancer. None of the trials were conducted in children. Mindfulness was associated with significant reductions in the severity of short-term anxiety (23 trials; 2339 participants; SMD, −0.51; 95% CI, −0.70 to −0.33; I2 = 76%). The association of mindfulness with short-term anxiety did not vary by evaluated patient, intervention, or study characteristics. Mindfulness was also associated with the reduction of medium-term anxiety (9 trials; 965 participants; SMD, −0.43; 95% CI, −0.68 to −0.18; I2 = 66%). No reduction in long-term anxiety was observed (2 trials; 403 participants; SMD, −0.02; 95% CI, −0.38 to 0.34; I2 = 68%). MBIs were associated with a reduction in the severity of depression in the short term (19 trials; 1874 participants; SMD, −0.73; 95% CI; −1.00 to −0.46; I2 = 86%) and the medium term (8 trials; 891 participants; SMD, −0.85; 95% CI, −1.35 to −0.35; I2 = 91%) and improved health-related quality of life in patients in the short term (9 trials; 1108 participants; SMD, 0.51; 95% CI, 0.20 to 0.82; I2 = 82%) and the medium term (5 trials; 771 participants; SMD, 0.29; 95% CI, 0.06 to 0.52; I2 = 57%).

Conclusions and Relevance

In this study, MBIs were associated with reductions in anxiety and depression up to 6 months postintervention in adults with cancer. Future trials should explore the long-term association of mindfulness with anxiety and depression in adults with cancer and determine its efficacy in more diverse cancer populations using active controls.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414391/