Increase Spirituality and Positive Emotions in Meditation with Oxytocin

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Increase Spirituality and Positive Emotions in Meditation with Oxytocin

 

By John M. de Castro, Ph.D.

 

“A meditation practice gives you the benefit of turning inward to your spirituality for answers, instead of looking to others. Meditation can drastically improve the loneliness, or longing you have in your life. Reach a state of interconnectedness with others and with your higher self, improve the joy you feel daily and become a compassionate person, free of fear and anxiety.” – EOC Institute

 

Spirituality is defined as “one’s personal affirmation of and relationship to a higher power or to the sacred.” Spirituality has been promulgated as a solution to the challenges of life both in a transcendent sense and in a practical sense. The transcendent claims are untestable with the scientific method. But, the practical claims are amenable to scientific analysis. There have been a number of studies of the influence of spirituality on the physical and psychological well-being of practitioners mostly showing positive benefits, with spirituality encouraging personal growth and mental health.

 

Oxytocin is a hormone and a neuromodulator that affects both the peripheral physiology and the brain. High levels of Oxytocin have been associated with high levels of social bonding and spirituality. But, the fact that the Oxytocin and spirituality are related does not demonstrate that there’s a causal connection. To determine if Oxytocin actually produces increased spirituality there is a need to manipulate its levels and observe its effects on spirituality. In today’s Research News article “Effects of oxytocin administration on spirituality and emotional responses to meditation.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040919/, Van Cappellen and colleagues examine the relationship of Oxytocin with spirituality by actively manipulating its levels and observing its effects on spirituality and well-being.

 

Van Cappellen and colleagues recruited meditation naïve males between the ages of 35 and 65 years and randomly assigned them to either receive Oxytocin or a placebo administered via a nasal spray in a double-blind fashion. Before administration the participants were genotyped for the oxytocin receptor gene. After administration the participants were administered a 20-minute guided meditation and measured for emotions afterward. Both before and after administration and 1 week later the participants completed two measures of spirituality, a measure of positive and negative emotions, and involvement in religious organizations.

 

They found that after oxytocin administration in comparison to placebo there was a significant, 33%, increase in spirituality, including interconnectedness and meaning and purpose, that were maintained one week later. They also had significantly greater positive emotions during and after meditation that were significantly mediated by the increases in spirituality. That is, oxytocin increased spirituality that, in turn, increased positive emotions associated with meditation. Finally, they found that these effects were modulated by variants of oxytocin receptor genes.

 

This was an interesting, tightly controlled study that demonstrated that elevated levels of oxytocin cause a lasting increase in spirituality and positive emotions during and after meditation. The fact that these effects are modulated by different variant of receptor genes suggests that different individuals are biologically predisposed to spirituality. So, spirituality is at least in part influenced by the biology and has the effect of improving the individuals’ mood.

 

So, increase spirituality and positive emotions in meditation with oxytocin.

 

“Awe involves that assimilation — giving up your cognitive structures in order to accommodate [the object of awe]. And mindfulness is a little bit about that too, because you’re paying attention and exercising non-conceptual awareness, so you should be more open to the immensity that’s there. You step out of the small frame that you have and this small idea of what the world is… You’re not stuck in your own story.” – Brian Ostafin

 

CMCS – Center for Mindfulness and Contemplative Studies

 

“This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Van Cappellen, P., Way, B. M., Isgett, S. F., & Fredrickson, B. L. (2016). Effects of oxytocin administration on spirituality and emotional responses to meditation. Social Cognitive and Affective Neuroscience, 11(10), 1579–1587. http://doi.org/10.1093/scan/nsw078

 

Abstract

The oxytocin (OT) system, critically involved in social bonding, may also impinge on spirituality, which is the belief in a meaningful life imbued with a sense of connection to a Higher Power and/or the world. Midlife male participants (N = 83) were randomly assigned to receive intranasal OT or placebo. In exploratory analyses, participants were also genotyped for polymorphisms in two genes critical for OT signaling, the oxytocin receptor gene (OXTR rs53576) and CD38 (rs6449182 and rs3796863). Results showed that intranasal OT increased self-reported spirituality on two separate measures and this effect remained significant a week later. It also boosted participants’ experience of specific positive emotions during meditation, at both explicit and implicit levels. Furthermore, the effect of OT on spirituality was moderated by OT-related genotypes. These results provide the first experimental evidence that spirituality, endorsed by millions worldwide, appears to be supported by OT.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040919/

Protect the Aging Brain with Meditation

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Protect the Aging Brain with Meditation

 

By John M. de Castro, Ph.D.

 

“long-term engagement in mindfulness meditation may enhance cognitive performance in older adults, and that with persistent practice, these benefits may be sustained. That’s great news for the millions of aging adults working to combat the negative effects of aging on the brain.” B. Grace Bullock

 

Human life is one of constant change. We revel in our increases in physical and mental capacities during development, but regret their decreases during aging. The aging process involves a systematic progressive decline in every system in the body, the brain included. Starting in the 20s there is a progressive decrease in the volume of the brain as we age.

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity.  Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread area. and have found that meditation practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. In addition, they have been able to investigate various techniques that might slow the process of neurodegeneration that accompanies normal aging. They’ve found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation and yoga have been found to degenerate less with aging than non-practitioners.

 

In today’s Research News article “Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447722/, Kurth and colleagues review and summarize the published research literature on the neuroprotective effects of meditation in the elderly. They discuss the ideas that the aging based deterioration of the brain is due to a number of processes, including changes in the DNA telomeres, inflammation, stress, and neuroplasticity and that meditation appears to effect all of these processes.

 

There has accumulated evidence that meditation protects against age related decline at the molecular genetic level. As we age the length of a DNA structures called the telomeres progressively shorten. It is thought that the shorter the telomeres get the more difficult it becomes for cells to replicate properly and thus leads to decline. Mindfulness training in general and meditation specifically, has been shown to reduce the shortening of the telomeres with aging. Kurth and colleagues speculate that this is one mechanism by which meditation protects the brain from age related decline.

 

As we age the natural inflammatory response that normally occurs to protect against infection begins to increase in general and lose its specificity to fighting particular diseases, pathogens, and injuries. It becomes more widespread damaging normal tissues. Mindfulness training in general and meditation specifically has been shown to reduce inflammatory responses. It seems reasonable that this is another mechanism by which meditation protects the body from age related decline.

 

Stress is present throughout life. But if it is too intense or prolonged the biological responses to stress begin to damage the body. These stress induced changes are similar to age related deterioration. Stress effects may accumulate over time. Hence, the older we get the greater the total stress induced damage. Mindfulness training in general and meditation specifically has been shown to improve emotion regulation and to reduce the physiological and psychological responses to stress. This is hypothesized to be another mechanism by which meditation protects the brain from deterioration with aging.

 

Neuroplasticity is a change in the size and connectivity of brain structures as they are exercised over a prolonged period of time. Mindfulness training in general and meditation specifically has been shown to produce neuroplastic changes in the brain, increasing the size and connectivity of brain structures. This process would tend to counteract brain degeneration with aging and may be another mechanism by which meditation protects the brain during aging.

 

Hence there has accumulated evidence that meditation reduces the deterioration of the brain with aging. It appears to do so by altering a number of different mechanisms including changes in the DNA telomeres, inflammation, stress, and neuroplasticity. This protection of the brain may be responsible to the ability of meditation to reduce the decline in mental abilities that occur with aging. This would tend to make aging a more benign process.

 

So, protect the aging brain with meditation.

 

We expected rather small and distinct effects located in some of the regions that had previously been associated with meditating. Instead, what we actually observed was a widespread effect of meditation that encompassed regions throughout the entire brain.” – Florian Kurth

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kurth, F., Cherbuin, N., & Luders, E. (2017). Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field. Frontiers in Psychology, 8, 860. http://doi.org/10.3389/fpsyg.2017.00860

 

Abstract

Over the last decade, an increasing number of studies has reported a positive impact of meditation on cerebral aging. However, the underlying mechanisms for these seemingly brain-protecting effects are not well-understood. This may be due to the fact, at least partly, that systematic empirical meditation research has emerged only recently as a field of scientific scrutiny. Thus, on the one hand, critical questions remain largely unanswered; and on the other hand, outcomes of existing research require better integration to build a more comprehensive and holistic picture. In this article, we first review theories and mechanisms pertaining to normal (brain) aging, specifically focusing on telomeres, inflammation, stress regulation, and macroscopic brain anatomy. Then, we summarize existing research integrating the developing evidence suggesting that meditation exerts positive effects on (brain) aging, while carefully discussing possible mechanisms through which these effects may be mediated.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447722/

Improve Well-Being in the Elderly with Tai Chi

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Improve Well-Being in the Elderly with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Practising the ancient martial art of Tai Chi is so beneficial to elderly people’s health that it should be “the preferred mode of training”, according to scientists.” – The Telegraph

 

We celebrate the increasing longevity of the population. But, aging is a mixed blessing. The aging process involves a systematic progressive decline of the body and the brain. Every system in the body deteriorates including motor function with a decline in strength, flexibility, and balance. It is inevitable. In addition, many elderly experience withdrawal and isolation from social interactions. There is some hope as there is evidence that these declines can be slowed. For example, a healthy diet and a regular program of exercise can slow the physical decline of the body with aging. Also, contemplative practices such as meditation, yoga, and tai chi or qigong have all been shown to be beneficial in slowing or delaying physical and mental decline.

 

Tai Chi has been practiced for thousands of years with benefits for health and longevity. Tai Chi training is designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Only recently though have the effects of Tai Chi practice been scrutinized with empirical research. But, it has been found to be effective for an array of physical and psychological issues. It appears to strengthen the immune system, reduce inflammation and increase the number of cancer killing cells in the bloodstream. Because Tai Chi is not strenuous, involving slow gentle movements, and is safe, having no appreciable side effects, it is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. Tai Chi has been shown to help the elderly improve attention, balance, reducing falls, arthritis, cognitive function, memory, and reduce age related deterioration of the brain.

 

In today’s Research News article “Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221552/, Chan and colleagues recruited “hidden elderly” participants, who were over 60 years of age and did not participate in any social activities. They were randomly assigned to either a control condition which received usual care or to receive Tai Chi practice for 60 minutes, twice a week for 3 months and were encouraged to practice at home for 30 minutes daily. They were measured before and after the 3-month practice period and 3 months later for their social network, social support, loneliness, mental health, self-esteem, and health quality of life.

 

They found compared to baseline and the control group that the group that practiced Tai Chi had significant improvements in loneliness, social support, and their physical quality of life that persisted for the three month follow-up period. There were no adverse events and the participants indicated that they were pleased with the practice. Hence, practicing Tai Chi was safe, acceptable, and effective; significantly improving the social, psychological, and physical conditions of the “hidden elderly.”

 

It is not clear that Tai Chi practice per se produced the benefits. Since the practice was twice a week in a group condition, these individuals who did not participate in social activities prior to the study, were thrust into a social context as a prerequisite for participation. Hence, the improvement in their social condition and their loneliness may be simply due to the required social participation. In future research, there needs to be a control condition with comparable social participation to ascertain if Tai Chi practice or simply social participation was responsible for the improvements.

 

Regardless of whether Tai Chi was responsible or not, getting the “hidden elderly” out of their isolated situation and engaging in social activities is important for their psychological and physical well-being. Tai Chi is safe and acceptable for the elderly, is a light exercise, can be practiced virtually anywhere at little of no cost, and promotes social engagement. So, it would seem to be an almost ideal vehicle to promote the well-being of the elderly.

 

So, improve well-being in the elderly with Tai Chi.

 

“With its integrative approach that strengthens the body while focusing the mind, tai chi addresses a range of physical and mental health issues—including bone strength, joint stability, cardiovascular health, immunity, and emotional well-being. Tai chi is especially useful for improving balance and preventing falls—a major concern for older adults.” – Stephanie Watson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Chan, A. W., Yu, D. S., & Choi, K. (2017). Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial. Clinical Interventions in Aging, 12, 85–96. http://doi.org/10.2147/CIA.S124604

 

Abstract

Purpose

To test the feasibility and preliminary effectiveness of a tai chi qigong program with the assistance of elderly neighborhood volunteers in strengthening social networks and enhancing the psychosocial well-being of hidden elderly.

Patients and methods

“Hidden elderly” is a term used to describe older adults who are socially isolated and refuse social participation. This pilot randomized controlled trial recruited 48 older adults aged 60 or above who did not engage in any social activity. They were randomized into tai chi qigong (n=24) and standard care control (n=24) groups. The former group underwent a three-month program of two 60-minute sessions each week, with the socially active volunteers paired up with them during practice. Standard care included regular home visits by social workers. Primary outcomes were assessed by means of the Lubben social network and De Jong Gieveld loneliness scales, and by a revised social support questionnaire. Secondary outcomes were covered by a mental health inventory and the Rosenberg self-esteem scale, and quality of life by using the 12-Item Short Form Health Survey. Data was collected at baseline, and at three and six months thereafter.

Results

The generalized estimating equations model revealed general improvement in outcomes among participants on the tai chi qigong program. In particular, participants reported a significantly greater improvement on the loneliness scale (B=−1.32, 95% confidence interval [CI] −2.54 to −0.11, P=0.033) and the satisfaction component of the social support questionnaire (B=3.43, 95% CI 0.10–6.76, P=0.044) than the control group.

Conclusion

The pilot study confirmed that tai chi qigong with elderly neighborhood volunteers is a safe and feasible social intervention for hidden elderly. Its potential benefits in improving social and psychological health suggest the need for a full-scale randomized controlled trial to reveal its empirical effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221552/

Improve Posttraumatic Stress Disorder (PTSD) with Mindfulness

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Improve Posttraumatic Stress Disorder (PTSD) with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mind-body exercise offers a low-cost approach that could be used as a complement to traditional psychotherapy or drug treatments. These self-directed practices give PTSD patients control over their own treatment and have few side effects.” – Sang Kim

 

Experiencing trauma is quite common. It has been estimated that 60% of men and 50% of women will experience a significant traumatic event during their lifetime. But, only a fraction will develop Post-Traumatic Stress Disorder (PTSD). But this still results in a frightening number of people with 7%-8% of the population developing PTSD at some point in their life. For military personnel, it’s much more likely for PTSD to develop with about 11%-20% of those who have served in a war zone developing PTSD.

 

PTSD involves a number of troubling symptoms including reliving the event with the same fear and horror in nightmares or with a flashback. PTSD sufferers avoid situations that remind them of the event this may include crowds, driving, movies, etc. and may avoid seeking help because it keeps them from having to think or talk about the event. They often experience negative changes in beliefs and feelings including difficulty experiencing positive or loving feelings toward other people, avoiding relationships, memory difficulties, or see the world as dangerous and no one can be trusted. Sufferers may feel hyperarousal, feeling keyed up and jittery, or always alert and on the lookout for danger. They may experience sudden anger or irritability, may have a hard time sleeping or concentrating, may be startled by a loud noise or surprise.

 

Obviously, these are troubling symptoms that need to be addressed. There are a number of therapies that have been developed to treat PTSD including, Mindfulness Based Stress Reduction (MBSR). It includes body scan, meditation, and yoga practices. Although MBSR has been used successfully to treat PTSD, it has always been implemented in addition to other treatments and has never been examined as a stand-alone treatment. In today’s Research News article “Mindfulness-Based Stress Reduction (MBSR) as a Standalone Intervention for Posttraumatic Stress Disorder after Mixed Traumatic Events: A Mixed-Methods Feasibility Study.” See summary below or view the full text of the study at: http://journal.frontiersin.org/article/10.3389/fpsyg.2017.01407/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_388380_69_Psycho_20170912_arts_A, Müller-Engelmann and colleagues examine the efficacy of MBSR as a stand-alone treatment for PTSD.

 

They recruited adult male and female patients who were diagnosed with PTSD as the result of experiencing interpersonal violence.  Mindfulness Based Stress Reduction (MBSR) was administered in 8 weekly-2 ½ hour sessions in combination with required practice at home. The patients were measured before and after treatment for mindfulness, depression, PTSD symptoms, trauma symptoms, and experience with the program. They were also interviewed after the program regarding their experience with and feelings about the program.

 

They found that following treatment there were significant reductions in PTSD symptoms and in depression. Also, they found that the greater the increase in mindfulness the greater the decrease in PTSD symptoms. During post-treatment interviews the patients reported an overall increase in their sense of well-being. No adverse reactions were observed. Hence, MBSR treatment appeared to be an acceptable, safe, and effective stand-alone treatment for PTSD.

 

It should be noted that there was not a control or comparison condition. This markedly limits the ability to conclude that MBSR was responsible for the improvements. There is a need to perform a randomized controlled clinical trial with an active control condition. In addition, over a third of the patients who started the program dropped out. The drop-outs had significantly greater PTSD symptoms than the completers. This suggests that modifications of the program must be undertaken to keep the most severely affected patients in the program. Nevertheless, the findings are encouraging and justify further research.

 

So, improve posttraumatic stress disorder (PTSD) with mindfulness.

 

“People who practiced mindfulness meditation about half an hour a day for 8 weeks saw a change in several brain structures related to learning, memory, emotion, and the fear response. These are all things that play a role in post-traumatic stress responses.” – Sara Staggs

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Müller-Engelmann M, Wünsch S, Volk M and Steil R (2017) Mindfulness-Based Stress Reduction (MBSR) as a Standalone Intervention for Posttraumatic Stress Disorder after Mixed Traumatic Events: A Mixed-Methods Feasibility Study. Front. Psychol. 8:1407. doi: 10.3389/fpsyg.2017.01407

 

Abstract

Objectives: There is promising evidence that mindfulness-based interventions are effective in reducing the symptoms of posttraumatic stress disorder (PTSD). However, until now, studies have often lacked a full clinical PTSD assessment, and interventions are often administered in addition to other interventions. This study examined the feasibility of mindfulness-based stress reduction (MBSR) as a standalone intervention in patients with PTSD who have experienced mixed traumatic events.

Method: Fourteen patients participated in 8 weeks of MBSR. The patients were assessed prior to treatment, post-treatment and at a 1-month follow-up through self-ratings (e.g., the Davidson Trauma Scale) and the Clinician-Administered PTSD Scale to determine the effects of the intervention. Furthermore, after the intervention, the patients participated in qualitative interviews regarding their experiences with MBSR and their ideas for future improvements.

Results: Nine patients finished the program, and these patients considered the exercises to be applicable and helpful. In the Clinician-Administered PTSD Scale, we found large effects regarding the reduction of PTSD symptoms among completers (Cohen’s d = 1.2). In the Davidson Trauma Scale, the effect sizes were somewhat lower (Cohen’s d = 0.6) but nevertheless confirmed the efficacy of MBSR in reducing PTSD symptoms. In the qualitative interviews, the patients reported an augmentation of wellbeing and improvement regarding the handling of difficult situations and more distance from the traumatic event.

Conclusion: Despite the large effects, the high dropout rates and the results of the post-treatment interviews suggest that the intervention should be better adapted to the needs of PTSD patients, e.g., by giving more information regarding the exercises and by including shorter exercises to manage acute distress.

http://journal.frontiersin.org/article/10.3389/fpsyg.2017.01407/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_388380_69_Psycho_20170912_arts_A