Improve Balance in Stroke Victims with Tai Chi Practice

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Improve Balance in Stroke Victims with Tai Chi Practice

 

By John M. de Castro, Ph.D.

 

“Stroke can impair balance, heightening the risk of a debilitating fall. But  . . .  stroke survivors can improve their balance by practicing the Chinese martial art of tai chi.” – ScienceDaily

 

Every year, more than 795,000 people in the United States have a stroke and it is the third leading cause of death, killing around 140,000 Americans each year. A stroke results from an interruption of the blood supply to the brain, depriving it of needed oxygen and nutrients. This can result in the death of brain cells and depending on the extent of the damage produce profound loss of function. Even after recovery from stroke patients can experience residual symptoms. Problems with balance and falling are very common.

 

There are a number of risk factors for stroke that are unchangeable, such as family history, age, and genes. But there are a very large number of factors that are under our control including high blood pressure, smoking, high cholesterol, poor diet, sedentariness, and obesity. Given this list it is clear that basic physical fitness and exercise would be excellent for stroke prevention. Yoga practice is an exercise that can be adapted to the needs and limitations of stroke victims. The ancient mindful movement technique Tai Chi and Qigong are very safe forms of gentle exercise that appears to be beneficial for stroke victims including improving balance. It is difficult to get stroke survivors to engage in exercise. Perhaps the practice of Tai Chi , since it is adaptable, very gentle, and fun, might be acceptable and effective in the treatment of stroke survivors.

 

In today’s Research News article “Effect of Tai Chi Exercise on Balance Function of Stroke Patients: A Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289026/ ), Wu and colleagues review summarize and perform a meta-analysis of the published research literature on the effectiveness of Tai Chi in improving balance and preventing falls in stroke survivors. They identified 6 randomized controlled trials for inclusion in the analysis.

 

They found that the published research reported that after Tai Chi practice the stroke victims demonstrated significantly better balance and walking ability and fewer falls than stroke victims who performed physical therapy or other exercises. Hence, the published research supports the conclusion that Tai Chi practice is a safe and effective exercise for stroke victims to improve balance and decrease the likelihood of falls.

 

Tai Chi is a gentle and safe exercise that is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion, such as stroke recovery. Also, Tai Chi is inexpensive to administer, can be performed in groups or alone, at home or in a facility, and can be quickly learned. In addition, it can be practiced in social groups. This can make it fun, improving the likelihood of long-term engagement in the practice. So, Tai Chi practice would appear to be an almost ideal gentle exercise to improve motor ability and balance and reduce falls in stroke victims.

 

So, improve balance in strike victims with tai chi practice.

 

“Stroke survivors are particularly at risk from falls, with evidence suggesting they suffer up to seven times as many falls per year than healthy adults. Tai Chi, an ancient Chinese martial art, could help prevent falls by improving people’s balance, muscle strength and endurance as well as providing psychological benefits.“ – Ruth Taylor-Piliae

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wu, S., Chen, J., Wang, S., Jiang, M., Wang, X., & Wen, Y. (2018). Effect of Tai Chi Exercise on Balance Function of Stroke Patients: A Meta-Analysis. Medical science monitor basic research, 24, 210-215. doi:10.12659/MSMBR.911951

 

Abstract

Background

Tai Chi is an ancient form of physical activity that has been shown to improve cardiovascular function, but to date there had been no comprehensive systematic review on the effect of Tai Chi exercise on balance function of patients with stroke. This study evaluated the effect of Tai Chi exercise on balance function in stroke patients.

Material/Methods

PubMed, Cochrane library, and China National Knowledge Information databases and the Wan Fang medical network were searched to collect the articles. The random-effects model was used to assess the effect of Tai Chi exercise on balance function of stroke patients.

Results

Six studies were chosen to perform the meta-analysis according to the inclusion and exclusion criteria. There were significant improvements of balance on Berg Balance Scale score (MD=4.823, 95% CI: 2.138–7.508), the standing balance with fall rates (RR=0.300, 95%CI: 0.120–0.770), functional reach test and dynamic gait index in Tai Chi intervention group compared to the control intervention group. However, the short physical performance battery for balance (SPBB) showed Tai Chi did not significantly improve the ability of balance for stroke patients (MD=0.293, 95%CI: −0.099~0.685).

Conclusions

Tai Chi exercise might have a significant impact in improving balance efficiency by increasing BBS score and reducing fall rate.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289026/

 

Improve Cognitive Function in Breast Cancer Survivors with Mindfulness

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Improve Cognitive Function in Breast Cancer Survivors with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Participation in a mindfulness-based stress reduction program yields robust and sustained improvement in cancer-related cognitive impairment, a prevalent and potentially debilitating condition that affects attention, memory and executive function in survivors.” – ScienceDaily

 

Receiving a diagnosis of cancer has a huge impact on most people. Feelings of depression, anxiety, and fear are very common and are normal responses to this life-changing and potentially life-ending experience. But cancer diagnosis is not necessarily a death sentence. Over half of the people diagnosed with cancer are still alive 10 years later and this number is rapidly increasing. But, surviving cancer carries with it a number of problems. Cognitive impairments are a frequent side effect of cancer treatment. This has been dubbed “chemo brain.” Patients often refer to it as a mental cloudiness.

 

The patients report problems including forgetting things, trouble concentrating, trouble remembering details like names and dates, trouble multi-tasking, like answering the phone while cooking, taking longer to finish things, disorganized and slower thinking, and trouble remembering common words. These cognitive impairments generally produce problems with work and even social relationships such that patients tend to isolate themselves. They can also produce treatment problems as the patients often forget to take their medications.

 

These problems result from the fact that chemotherapy, radiation therapy and many cancer drugs directly affect the nervous system. At present, there are no known treatments for these cognitive impairment side effects of chemotherapy. Contemplative practices have been shown to affect memory and have positive effects on cancer treatment and recovery.  There is some evidence that contemplative practices may be useful for the alleviation of “chemo brain” symptoms. So, it makes sense to step back and review what is known regarding the ability of mindfulness training to improve the cancer patient’s cognitive abilities.

 

In today’s Research News article “Mindfulness-based interventions and cognitive function among breast cancer survivors: a systematic review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260900/ ), Cifu and colleagues review and summarize the published research studies on the effectiveness of mindfulness training for the cognitive deficits present after recovery from breast cancer. They identified 6 studies; 5 of which were randomized controlled studies and 4 of which used the Mindfulness-Based Stress Reduction (MBSR) program.

 

They found mixed results from the studies but the majority found that mindfulness training produced significant improvements in the cognitive abilities of the patients. The 2 studies that reported follow-up data demonstrated that the improvements were sustained 2 and 6 months after the end of the program. These mixed findings suggest that mindfulness training may be useful in treating the problems with thinking, memory, and attention that result from treatment for breast cancer, but more research is needed to reach firm conclusions.

 

It is not known what the mechanism might be by which mindfulness training relieves these cognitive impairments. But it has been previously demonstrated that mindfulness training improves cognition in healthy and aging populations by changing the brain, particularly the frontal cortical regions. It is possible that this is the same phenomenon only with breast cancer survivors.

 

So, improve cognitive function in breast cancer survivors with mindfulness.

 

“Mindfulness-based stress reduction (MBSR) may improve cognitive function in breast and colorectal cancer survivors.” Neurology Advisor

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Cifu, G., Power, M. C., Shomstein, S., & Arem, H. (2018). Mindfulness-based interventions and cognitive function among breast cancer survivors: a systematic review. BMC cancer, 18(1), 1163. doi:10.1186/s12885-018-5065-3

 

Abstract

Background

Breast cancer survivors have an elevated risk of cognitive impairment compared to age-matched women without cancer. Causes of this impairment are complex, including both treatment and psychological factors. Mindfulness-based interventions, which have been shown to improve cognitive function in the general population, may be one approach to mitigate cognitive impairment in this survivor population. Our objective was to conduct a systematic literature review of studies on the effect of mindfulness-based interventions on cognition among breast cancer survivors.

Methods

We conducted searches of three electronic databases (Scopus, PubMed and Cochrane Database of Systematic Reviews) in September 2017 for studies pertaining mindfulness and cognitive function among breast cancer survivors. Abstracts were manually searched by two reviewers and additional articles were identified through reference lists.

Results

A total of 226 articles were identified through our systematic search and six met inclusion criteria for this review. The reviewed studies lacked consistency in terms of the cognition domains studied (e.g. executive function, recent memory, etc) and in the measures used to assess cognition. Of the included studies, two found no association between mindfulness interventions and cognitive function, two found improvement that was not sustained at the follow-up, and another two found sustained improvement at 2- or 6-months.

Conclusions

Mindfulness-based interventions have shown some evidence for improving cognition among breast cancer survivors, but further research using validated and comprehensive cognitive assessments is needed. More research is also needed related to the timing, duration and content of mindfulness interventions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260900/

 

Develop Transformational Leadership with Mindfulness

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Develop Transformational Leadership with Mindfulness

 

By John M. de Castro, Ph.D.

 

“there is a definite impact on leadership skills by practicing mindfulness, such as increase in productivity, decision-making, listening,, and reduction in stress levels. But for leaders, the biggest benefit of mindfulness is its direct impact on the development of emotional intelligence.” – Monica Thakrar

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. How we spend that time is immensely important for not only to productivity in the workplace but also to our psychological and physical health. Mindfulness practices have been implemented in the workplace and they have been shown to markedly reduce the physiological and psychological responses to stress. This, in turn, improves productivity and the well-being of the employees. As a result, many businesses have incorporated mindfulness practices into the workday.

 

Mindfulness may also help to promote leadership in the workplace. It can potentially do so by enhancing emotion regulation, making the individual better able to recognize, experience, and adaptively respond to their emotions, and making the leader better able to listen to and to understand the needs and emotion of the workers they lead. There has been, however, little research attention to the effects of mindfulness on leadership.

 

In today’s Research News article “When Mindfulness Interacts With Neuroticism to Enhance Transformational Leadership: The Role of Psychological Need Satisfaction.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2018.02588/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_862317_69_Psycho_20190101_arts_A ), Decuypere and colleagues recruited nurses who were in leadership positions (head nurses) in nursing care facilities. They completed measures of mindfulness, transformational leadership, need satisfaction, emotional stability (neuroticism), autonomy, competence, and relatedness.

 

They found that the higher the levels of mindfulness, the higher the levels of transformational leadership, autonomy, competence, and relatedness and the lower the levels of neuroticism. Conversely, the higher the levels of neuroticism the lower the levels of mindfulness, transformational leadership, autonomy, competence, and relatedness. They then examined whether the association of mindfulness with transformational leadership was mediated by mindfulness’ association with the other variables. They found that the association of mindfulness with transformational leadership was completely mediated by its associations with need satisfaction and competence, and partially mediated by its association with autonomy and relatedness. They further demonstrated that neuroticism affected these relationships such that when neuroticism was higher there was a stronger relationship between mindfulness and need satisfaction and competence than when neuroticism was low.

 

These are interesting results that suggest that mindfulness affects the ability of head nurses to be transformational leaders and that this is amplified when there are low levels of emotional stability. Furthermore, these results suggest that mindfulness is associated with the nurses’ ability to regulate their emotions and this is what makes them better leaders. Hence, when they lack emotional stability, mindfulness has even great impacts.

 

This all suggests that the ability to lead others emanates from one’s ability to deal with one’s own emotions and this is strongly influenced by mindfulness. It has been well established that mindfulness produces a greater ability to experience and adaptively respond to emotions, emotion regulation. What is new here is that this is related to leadership.

 

So, develop transformational leadership with mindfulness.

 

“The key to effective leadership is the ability to integrate your head (IQ) with your heart (EQ). . . Our hearts are where essential leadership qualities like passion, compassion and courage reside. By practicing mindfulness, mindful leaders exhibit high levels of self-awareness and intentionality in their actions.” – Bill George

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Decuypere A, Audenaert M and Decramer A (2018) When Mindfulness Interacts With Neuroticism to Enhance Transformational Leadership: The Role of Psychological Need Satisfaction. Front. Psychol. 9:2588. doi: 10.3389/fpsyg.2018.02588

 

Transformational leadership is a popular and well-researched leadership style. Although much is understood about its positive consequences, less research has focused on antecedents of transformational leadership. In this research we draw upon self-determination theory and incorporate a self-regulatory approach to investigate if and how leader mindfulness influences transformational leadership. The analyses show that autonomy, competence and relatedness need satisfaction mediate between mindfulness and transformational leadership, indicating that mindfulness is associated with psychological need satisfaction. Furthermore, the data show that neuroticism moderates the relationship between mindfulness and relatedness need satisfaction. Generally speaking, the association between mindfulness and relatedness need satisfaction is positive. When neuroticism is also high, mindfulness has the largest impact. Or conversely, when emotional stability is high, mindfulness has the smallest association with relatedness need satisfaction. This is in line with evidence suggesting that mindfulness may primarily exert its influence through emotional self-regulation. Furthermore, the moderated mediation model for relatedness need satisfaction is significant, indicating that neuroticism is a boundary condition for the indirect effect of mindfulness on transformational leadership through relatedness need satisfaction.

https://www.frontiersin.org/articles/10.3389/fpsyg.2018.02588/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_862317_69_Psycho_20190101_arts_A

 

Mindfulness Measured by Paper and Pencil Test does Not Predicts Real World Behavior

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Mindfulness Measured by Paper and Pencil Test does Not Predicts Real World Behavior

 

By John M. de Castro, Ph.D.

 

“I’m recognizing as I write this that even this moment will come and pass, and as I feel that, I notice some relief in my chest and my shoulders widening and releasing to let my heart relax. I’m being mindful that my day is winding down, and the thought is hitting me: “the work before me will get done.”- Elizabeth Ann Rue

 

A prerequisite in science is that in order to study something you have to be able to reliably and validly measure it. With many concepts such as mindfulness, depression, and anxiety that reflect subjective states, there are currently no objective means to measure them. Measurement then falls to some kind of after the fact test or to a self-report. Traditionally, mindfulness has been measured with paper and pencil psychometric tests, such as the Five Facets of Mindfulness Questionnaire. They ask the participant to answer the question in regard to their overall, general state of mindfulness.  It is unclear whether these subjective questionnaire reports are reliable, accurate, and honest and whether they relate to actual behavior of people in their natural, everyday environments. Hence it is important to investigate whether the results of these self-report tests actually predict what the people will do in their everyday life.

 

In today’s Research News article “Dispositional mindfulness in daily life: A naturalistic observation study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261408/ ), Kaplan and colleagues performed two studies to determine first what people expect the behavior of mindful people to look like and second whether actual behavior conforms to these expectations. In a first study they recruited adults online and had them complete measures of their perceptions of the behavior of mindful people. They found that “laypersons assume that mindfulness relates to (1) attention to sensory perceptions, (2) emotional positivity, (3) quality social interactions, and (4) a prosocial orientation in daily life.”

 

In a second study, they recruited adults and randomly assigned them to either a control condition or to receive 8 weeks of meditation training they were measured before and after training for mindfulness and personality characteristics and wore a recording device over a weekend that recorded 50 seconds of sounds every 9 minutes. The sound samples were transcribed and analyzed for amount of time talking to others, positive and negative words, perception words (e.g., hear, see, feel, soft, loud), substantive, meaningful, conversations, and prosocial orientation (gratitude, affection, gossip, complaining).

 

They found that the level of mindfulness of the participant was positively related to the perceptual orientation, use of words indicating sensations, but was not reliably associated with positivity, negativity, social interactions, prosocial, or antisocial interactions. Hence, the actual observations of the participants behavior were not in line with the expectations people have about the behavior of mindful people.

 

The results suggest that mindful people are more tuned into their perceptual worlds, which is an expectation about the present moment awareness of mindful people. But, in other ways, people high in trait mindfulness were not especially socially, emotionally, or prosocially oriented. This may indicate that mindfulness measured with paper and pencil tests is not a valid indicator of actual mindful behavior. On the other hand, they may indicate that peoples expectations about the observable behavior of mindful people are incorrect.

 

This study is important in that it investigated actual, objectively defined behaviors by people that are expressed in their natural, everyday environments. This kind of analysis may prove to be a better actual measure of mindfulness than questionnaires and tests. It remains for future research to investigate this more thoroughly. But this study opens up a new and potentially important realm for the investigation of mindfulness.

 

“How often have you rushed out the door and into your day without even thinking about how you’d like things to go? Before you know it, something or someone has rubbed you the wrong way, and you’ve reacted automatically with frustration, impatience, or rage—in other words, you’ve found yourself acting in a way you never intended. You don’t have to be stuck in these patterns. Pausing to practice mindfulness for just a few minutes at different times during the day can help your days be better, more in line with how you’d like them to be.” – Parneet Pal

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kaplan, D. M., Raison, C. L., Milek, A., Tackman, A. M., Pace, T., & Mehl, M. R. (2018). Dispositional mindfulness in daily life: A naturalistic observation study. PloS one, 13(11), e0206029. doi:10.1371/journal.pone.0206029

 

Abstract

Mindfulness has seen an extraordinary rise as a scientific construct, yet surprisingly little is known about how it manifests behaviorally in daily life. The present study identifies assumptions regarding how mindfulness relates to behavior and contrasts them against actual behavioral manifestations of trait mindfulness in daily life. Study 1 (N = 427) shows that mindfulness is assumed to relate to emotional positivity, quality social interactions, prosocial orientation and attention to sensory perceptions. In Study 2, 185 participants completed a gold-standard, self-reported mindfulness measure (the FFMQ) and underwent naturalistic observation sampling to assess their daily behaviors. Trait mindfulness was robustly related to a heightened perceptual focus in conversations. However, it was not related to behavioral and speech markers of emotional positivity, quality social interactions, or prosocial orientation. These findings suggest that the subjective and self-reported experience of being mindful in daily life is expressed primarily through sharpened perceptual attention, rather than through other behavioral or social differences. This highlights the need for ecological models of how dispositional mindfulness “works” in daily life, and raises questions about the measurement of mindfulness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261408/

 

Improve Treatment Resistant Major Depression with Yoga

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Improve Treatment Resistant Major Depression with Yoga

 

By John M. de Castro, Ph.D.

 

“Some people who haven’t responded to traditional treatments might do well with yoga, because unlike antidepressant drugs, yoga and deep breathing target the autonomic nervous system.” – Amanda MacMillan

 

Clinically diagnosed depression is the most common mental illness, affecting over 6% of the population. Major depression can be quite debilitating. Depression can be difficult to treat and is usually treated with anti-depressive medication. But, of patients treated initially with drugs only about a third attained remission of the depression. After repeated and varied treatments including drugs, therapy, exercise etc. only about two thirds of patients attained remission. But drugs often have troubling side effects and can lose effectiveness over time. In addition, many patients who achieve remission have relapses and recurrences of the depression. Even after remission some symptoms of depression may still be present (residual symptoms).

 

Being depressed and not responding to treatment or relapsing is a terribly difficult situation. The patients are suffering and nothing appears to work to relieve their intense depression. Suicide becomes a real possibility. So, it is imperative that other treatments be identified that can relieve the suffering. Mindfulness training is an alternative treatment for depression. It has been shown to be an effective treatment for depression and its recurrence and even in the cases where drugs fail.  Yoga practice is a mindfulness training and has the added benefit of being an exercise which has been also found to be effective for depression.

 

Recently, it has been discovered that there are genetic differences between patients with major depression who respond to antidepressant drugs and those who don’t. In particular non-responders appear to have a 5-HTTLPR variant of the serotonin transporter gene (SLC6A4) and MTHFR 677C>T polymorphisms. The serotonin system in the brain is a target of antidepressant drugs and these genetic variants may underlie non-responsiveness to the drugs. Since, yoga practice appears to be effective for depression in patients who do not respond to antidepressant drugs, it is likely that yoga practice works in spite of these genetic variants.

 

In today’s Research News article “5-HTTLPR and MTHFR 677C>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder: A randomized active-controlled trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278208/ ), Tolahunase and colleagues recruited patients with major depressive disorder and randomly assigned them to receive either a 12-week yoga program or to receive antidepressant drugs (SSRIs). Yoga was practiced for 2 hours per day, 5 days per week, for 12 weeks and consisted of postures, breathing exercises, and meditation. They were measured before and after treatment for depression, other psychiatric conditions, and childhood trauma. Blood was drawn for DNA genotyping.

 

They found that both groups had significant reductions in depression over the treatment period, but, the yoga group had significantly greater reductions in depression and higher remission rates (59% compared to 33%) than the antidepressant drug group. The participants with 5-HTTLPR and MTHFR 677C>T polymorphisms had significantly lower reductions in depression and remission rates in the antidepressant drug group but not in the yoga group. The participants in the yoga group with the polymorphisms benefited with reductions in depression and increases in remission rates to the same extent as those without the polymorphisms.

 

These are remarkable results. Yoga practice produced greater relief of depression than antidepressant drugs and, in addition, yoga practice produced this relief irrespective of the genetic polymorphisms that affect responses to antidepressant drugs. This suggests that yoga practice my work to relieve depression through a different mechanism than antidepressant drugs. Hence, yoga practice appears to be an almost ideal treatment for major depressive disorder, producing high remission rates and great reductions in depression, safely, without major side effects, and irrespective of the genetic polymorphisms that reduce responsiveness to antidepressant drugs. This suggests that yoga practice should be the first line treatment for major depressive disorder.

 

So, improve treatment resistant major depression with yoga

 

“many patients dealing with depression, anxiety, or stress, yoga may be a very appealing way to better manage symptoms. Indeed, the scientific study of yoga demonstrates that mental and physical health are not just closely allied, but are essentially equivalent. The evidence is growing that yoga practice is a relatively low-risk, high-yield approach to improving overall health.” – Harvard Mental Health Newsletter

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Tolahunase, M. R., Sagar, R., & Dada, R. (2018). 5-HTTLPR and MTHFR 677C>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder: A randomized active-controlled trial. Indian journal of psychiatry, 60(4), 410-426.

 

Abstract

Background:

There is growing evidence suggesting that both genetic and environmental factors modulate treatment outcome in, a highly heterogeneous, major depressive disorder (MDD). 5-HTTLPR variant of the serotonin transporter gene (SLC6A4) and MTHFR 677C>T polymorphisms have been linked to the pathogenesis of MDD, and antidepressant treatment response. The evidence is lacking on the clinical utility of yoga in patients with MDD who have 5-HTTLPR and MTHFR 677C>T polymorphisms and less likely to respond to medications (SSRIs).

Aims:

We aimed to examine the impact of YBLI in those who have susceptible 5-HTTLPR and MTHFR 677C>T polymorphisms and are less likely to drug therapy with SSRIs.

Settings and Design:

In a 12 week randomized active-controlled trial, MDD patients (n = 178) were randomized to receive YBLI or drug therapy.

Methods:

Genotyping was conducted using PCR-based methods. The clinical remission was defined as BDI-II score ≤ 9.

Statistical Analysis Used:

An intent-to-treat analysis was performed, and the association of genotype with treatment remission consisted of the logistic regression model. A P value of <0.05 was considered statistically significant.

Results:

Multivariate logistic regression models for remission including either 5-HTTLPR or MTHFR 677C>T genotypes showed statistically significant odds of remission in YOGA arm vs. DRUG arm. Neither 5-HTTLPR nor MTHFR 677C>T genotype showed any influence on remission to YBLI (P = 0.73 and P = 0.64, respectively). Further analysis showed childhood adversity interact with 5-HTTLPR and MTHFR 677C>T polymorphisms to decrease treatment response in DRUG treatment arm, but not in YOGA arm.

Conclusions:

YBLI provides MDD remission in those who have susceptible 5-HTTLPR and MTHFR 677C>T polymorphisms and are resistant to SSRIs treatment. YBLI may be therapeutic for MDD independent of heterogeneity in its etiopathogenesis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278208/

 

Improve Health with Qigong

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Improve Health with Qigong

 

By John M. de Castro, Ph.D.

 

“The health benefits from Qigong and Tai Chi comes about both by supporting the body’s natural tendency to return to balance and equilibrium and also gently yet profoundly creating strength, flexibility and balance in the muscles and joints through gentle flowing movements.” – Denise Nagel

 

Qigong and Tai Chi have been practiced for thousands of years with benefits for health and longevity. Qigong and Tai Chi training are designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Only recently though have the effects of Qigong practice been scrutinized with empirical research. It has been found to be effective for an array of physical and psychological issues. It appears to strengthen the immune system, reduce inflammation, increase the number of cancer killing cells in the bloodstream and improve cardiovascular function.

 

Because Qigong is not strenuous, involving slow gentle movements, and is safe, having no appreciable side effects, it is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. So, with indications of so many benefits it makes sense to step back and review the research on the effects of Qigong training on health and well-being.

 

In today’s Research News article “Beneficial Effects of Qigong Wuqinxi in the Improvement of Health Condition, Prevention, and Treatment of Chronic Diseases: Evidence from a Systematic Review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220394/ ), Guo and colleagues review and summarize the published research literature on the effects of Qigong practice on physical and psychological health. They found 28 published research studies.

 

They report that the research finds that Qigong practice by healthy adults produces improvements in cognitive functions including concentration and attention, strengthens the immune system, improves body shape and size, physical function, and the cardiovascular system, improves mood and psychological well-being, improves lipid metabolism, slows physiological indicators of aging, and reduces inflammation. For clinical populations, they report that the research indicates that Qigong practice reduces depression, and improves osteoarthritis, including knee osteoarthritis, metabolic syndrome, and blood fat levels.

 

Conclusions from these very exciting findings must be tempered as the research methodologies were often weak. More tightly controlled studies are needed. Regardless, these findings suggest that Qigong practice produces improved physical and psychological health in both healthy adults and people with mental and physical diseases. These are a remarkable set of benefits from this simple practice and suggest the reason why it has continued to be practiced by large numbers of people for hundreds of years. Hence, this simple, inexpensive, convenient, safe, and fun practice may improve the participants ability to successfully conduct their lives, improving health and well-being.

 

So, improve health with Qigong.

 

““A compelling body of research emerges when Tai Chi studies and the growing body of Qigong studies are combined. The evidence suggests that a wide range of health benefits accrue in response to these meditative movement forms.” – Dr. Mercola

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Guo, Y., Xu, M., Wei, Z., Hu, Q., Chen, Y., Yan, J., & Wei, Y. (2018). Beneficial Effects of Qigong Wuqinxi in the Improvement of Health Condition, Prevention, and Treatment of Chronic Diseases: Evidence from a Systematic Review. Evidence-based complementary and alternative medicine : eCAM, 2018, 3235950. doi:10.1155/2018/3235950

 

Abstract

Purpose

Qigong is a modality of traditional Chinese mind-body medicine that has been used to prevent and cure ailments, to improve health in China for thousands of years. Wuqinxi, a Chinese traditional Qigong that focuses on mind-body integration, is thought to be an effective exercise in promoting physical and mental wellbeing. Thus, we summarized the evidence and aim to unravel effects of Wuqinxi on health outcomes.

Methods

We performed a systematic review of Wuqinxi studies published in English or Chinese since 1979. Relevant English and Chinese language electronic data bases were used for literature search. The selection of studies, data extraction, and validation were performed independently by two reviewers.

Results

A total of 28 eligible studies were included in this review, among which three are 3 in English and 25 in Chinese. The studies included in this review involve three different experimental designs: (1) 16 RCTs; (2) 2 historical cohort studies; and (3) 10 pretest and posttest studies (PPS). Participants in this review are categorized as either healthy or clinical populations. The results from this systematic review support the notion that Wuqinxi may be effective as an adjunctive rehabilitation method for improving psychological and physiological wellbeing among different age of healthy populations in addition to alleviating and treating diseases among various clinical populations.

Conclusion

The results indicated that Wuqinxi has been thought to be beneficial to improve health and treat chronic diseases. However, the methodological problems in the majority of included studies make it difficult to draw firm conclusive statements. More methodologically rigorous designed large-scale RCTs with a long-term follow-up assessment should be further conducted to examine the effects of Wuqixi on health-related parameters and disease-specific measures in different health conditions. This systematic review lends insight for future studies on Wuqinxi and its potential application in preventive and rehabilitation medicine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220394/

 

Meditation Alters Brain Responses to Negative Stimuli

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Meditation Alters Brain Responses to Negative Stimuli

 

By John M. de Castro, Ph.D.

 

“meditation facilitates strengthening the Assessment Center, weakening the unhelpful aspects of the Me Center (that can cause you to take things personally), strengthening the helpful parts of the Me Center (involved with empathy and understanding others) and changing the connections to/from the bodily sensation/fear centers such that you experience sensations in a less reactive, more balanced and holistic way. In a very real way, you literally are changing your brain for the better when you meditate.” – Rebecca Gladding

 

There has accumulated a large amount of research demonstrating that mindfulness has significant benefits for psychological, physical, and spiritual wellbeing. It even improves high level thinking known as executive function. Its positive effects are so widespread that it is difficult to find any other treatment of any kind with such broad beneficial effects on everything from thinking to mood and happiness to severe mental and physical illnesses. This raises the question of how mindfulness training could produce such widespread and varied benefits.

 

Mindfulness practice has been shown to produce improved emotion regulation. Practitioners demonstrate the ability to fully sense and experience emotions, but respond to them in more appropriate and adaptive ways. In other words, mindful people are better able to experience yet control emotions. This ability of mindfulness training to improve emotion regulation may be the basis for a wide variety of benefits that mindfulness provides to mental health.

 

Mindfulness practices may result in beneficial changes in the nervous system that underlie emotion regulation. The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity. Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread areas. In other words, mindfulness practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits.

 

In today’s Research News article “Does Meditation Alter Brain Responses to Negative Stimuli? A Systematic Review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243128/ ), Magalhaes and colleagues review and summarize the published research literature on the ability of mindful practice to alter brain responses to improve the regulation of emotions especially reactions to negative events.

 

They identified 11 published studies that used functional Magnetic Resonance Imaging (fMRI) to assess brain responses to negative stimuli before and after mindfulness training. Six of these studies involved a comparison to a control group while five involved before after comparisons. They found that the research, in general, indicated that mindfulness training resulted in greater activation of the frontal and prefrontal cortical regions of the brain in response to negative emotion eliciting stimuli. A number of studies also identified greater activation of the insular cortical region.

 

These are interesting findings as the frontal and prefrontal cortical regions have been identified as involved in higher level thought processes and particularly attentional processes. This suggests that a top down, cognitive, regulation of emotion is elicited to negative stimuli. Hence, it appears that individuals, trained in mindfulness, deal with negative emotions with attention and reason, analyzing the reality of the situation, and thereby responding less intensely and more adaptively and appropriately.

 

The insular region has been shown to be involved in body sense, particularly interoceptive awareness of the state of the body. Its heightened response to negative stimuli after mindfulness training suggests that trained individuals have a heightened sense of how their bodies are responding to a negative emotion. Many people are unaware of their physiological reactions to emotions. By improving this internal awareness mindfulness training may make individuals better able to detect when a emotion is arising and thereby better able to regulate it.

 

Hence, the published research indicates that mindfulness training results in changes to the brain that improve the detection of emotional reactions and the ability to attend to and rationally process the conditions that elicited them. These neuroplastic changes to the brain may underlie the ability of mindfulness training to enhance emotion regulation in response to negative situations and thereby improve the mental health of practitioners.

 

“Now, as the popularity of mindfulness grows, brain imaging techniques are revealing that this ancient practice can profoundly change the way different regions of the brain communicate with each other – and therefore how we think – permanently.” – Tom Ireland

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Magalhaes, A. A., Oliveira, L., Pereira, M. G., & Menezes, C. B. (2018). Does Meditation Alter Brain Responses to Negative Stimuli? A Systematic Review. Frontiers in human neuroscience, 12, 448. doi:10.3389/fnhum.2018.00448

 

Abstract

Background: Despite several attempts to review and explain how meditation alters the brain and facilitates emotion regulation, the extent to which meditation and emotion regulation strategies share the same neural mechanisms remains unclear.

Objective: We aim to understand the influence of meditation on the neural processing of negative emotional stimuli in participants who underwent meditation interventions (naive meditators) and long-term meditators.

Methodology: A systematic review was conducted using standardized search operators that included the presence of terms related to emotion, meditation and neuro-imaging techniques in PsycInfo, PubMed, Scopus, and Web of Science databases.

Results: Searches identified 882 papers, of which 11 were eligible for inclusion. Results showed a predominance of greater prefrontal/frontal activity related to meditation, which might indicate the increased recruitment of cognitive/attentional control resources in naïve and long-term meditators. This increased frontal activity was also observed when participants were asked to simply react to negative stimuli. Findings from emotion-related areas were scarce but suggested increased insular activity in meditators, potentially indicating that meditation might be associated with greater bodily awareness.

Conclusions: Meditation practice prompts regulatory mechanisms when participants face aversive stimuli, even without an explicit request. Moreover, some studies reported increased insular activity in meditators, consistent with the hypothesis that meditation helps foster an interoceptive awareness of bodily and emotional states.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243128/

 

Meditation’s Reduction of Pain is Independent of Brain Opioid Systems

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Meditation’s Reduction of Pain is Independent of Brain Opioid Systems

 

By John M. de Castro, Ph.D.

 

“Bit by bit, as I sat noticing my breath and body sensations, I began to feel the deep knots of pain in my body start to untie themselves.” – Avi Craimer

 

We all have to deal with pain. It’s inevitable, but hopefully it’s mild and short lived. For a wide swath of humanity, however, pain is a constant in their lives. At least 100 million adult Americans have chronic pain conditions. The most common treatment for chronic pain is drugs. These include over-the-counter analgesics and opioids. Opioids act on a system in the brain that contains receptors that respond to these drugs. But opioids are dangerous and highly addictive. Prescription opioid overdoses kill more than 14,000 people annually. So, there is a great need to find safe and effective ways to lower the psychological distress and improve the individual’s ability to cope with the pain.

 

Pain involves both physical and psychological issues. The stress, fear, and anxiety produced by pain tends to elicit responses that actually amplify the pain. So, reducing the emotional reactions to pain may be helpful in pain management. There is an accumulating volume of research findings to demonstrate that mind-body therapies have highly beneficial effects on the health and well-being of humans. Mindfulness practices have been shown to improve emotion regulation producing more adaptive and less maladaptive responses to emotions. Indeed, mindfulness practices are effective in treating pain in adults. It is not known whether meditations effects on pain are mediated by the same system that responds to opioids.

 

In today’s Research News article “Enhancement of Meditation Analgesia by Opioid Antagonist in Experienced Meditators.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162167/  ), May and colleagues recruited adult experienced meditators who were free of chronic pain and not taking opioid drugs. They were measured for pain responses to an electric shock delivered to the ring finger of the non-dominant hand. They rated the level of pain on a 10-point scale. The participants first rated pain under normal conditions and later while meditating. Those participants who demonstrated a 15% or more reduction in pain while meditating (meditation analgesia) participated in the second half of the experiment. Half the participants received a saline injection and half an injection of Naloxone (an opioid receptor blocker) and repeated the pain testing while meditating. In the next session the participants received either the saline or Naloxone injection that they did not receive in the first session. So, all participants received both saline and Naloxone injections and were tested for their pain sensitivity.

 

They found in the initial test that 85% of the participants demonstrated a 15% or more reduction in pain while meditating (meditation analgesia). This high rate suggests that meditation routinely produces a reduced experience of pain in experienced meditators. In the second phase they found that meditation analgesia was not only not reduced by Naloxone injection but actually significant increased, with larger reductions in both pain intensity and pain unpleasantness to the electric shock after Naloxone injection than after saline injections.

 

The opioid system of the brain is a well-established pain processing system. Its function is blocked by Naloxone. So, the reduction in pain produced by meditation was not affected by disrupting the opioid system. So, meditation analgesia must not be due to changes in this opioid system. It must be processed by a different system in the brain. The increase in meditation analgesia after Naloxone was a surprise, for which there is no viable explanation at this time. Hence, meditation reduces pain sensitivity and does so independent of the brain system that responds to opiates.

 

So, meditation reduces pain sensitivity independent of brain opioid systems.

 

“Mindfulness meditation is believed to be a viable alternative to drugs when it comes to pain management. Although research is still in the beginning phases, pilot studies focusing on the benefits of mindfulness have shown promising outcomes for patients suffering from chronic ailments such as fibromyalgia, back pain, migraines, etc.” – Mindworks

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

May, L. M., Kosek, P., Zeidan, F., & Berkman, E. T. (2018). Enhancement of Meditation Analgesia by Opioid Antagonist in Experienced Meditators. Psychosomatic medicine, 80(9), 807-813.

 

ABSTRACT

Objective

Studies have consistently shown that long-term meditation practice is associated with reduced pain, but the neural mechanisms by which long-term meditation practice reduces pain remain unclear. This study tested endogenous opioid involvement in meditation analgesia associated with long-term meditation practice.

Methods

Electrical pain was induced with randomized, double-blind, cross-over administration of the opioid antagonist naloxone (0.15-mg/kg bolus dose, then 0.2-mg/kg per hour infusion dose) with 32 healthy, experienced meditation practitioners and a standardized open monitoring meditation.

Results

Under saline, pain ratings were significantly lower during meditation (pain intensity: 6.41 ± 1.32; pain unpleasantness: 3.98 ± 2.17) than at baseline (pain intensity: 6.86 ±1.04, t(31) = 2.476, p = .019, Cohen’s d= 0.46; pain unpleasantness: 4.96 ±1.75, t(31) = 3.746, p = .001, Cohen’s d = 0.68), confirming the presence of meditation analgesia. Comparing saline and naloxone revealed significantly lower pain intensity (t(31) = 3.12, p = .004, d = 0.56), and pain unpleasantness (t(31) = 3.47, p = .002, d = 0.62), during meditation under naloxone (pain intensity: 5.53 ± 1.54; pain unpleasantness: 2.95 ± 1.88) than under saline (pain intensity: 6.41 ± 1.32; pain unpleasantness: 3.98 ± 2.17). Naloxone not only failed to eliminate meditation analgesia but also made meditation analgesia stronger.

Conclusions

Long-term meditation practice does not rely on endogenous opioids to reduce pain. Naloxone’s blockade of opioid receptors enhanced meditation analgesia; pain ratings during meditation were significantly lower under naloxone than under saline. Possible biological mechanisms by which naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162167/

 

Improve Physical and Mental Health with Musculoskeletal Disorders with Mindfulness Practices

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Improve Physical and Mental Health with Musculoskeletal Disorders with Mindfulness Practices

 

By John M. de Castro, Ph.D.

 

“Musculoskeletal disorders (MSDs) is the term given to a variety of painful conditions that affect the muscles, bones, and joints, which are a leading cause of long term sickness absence. . .MSDs are also at risk of developing symptoms of depression . . . Being off work for a significant period of time, whether due to an musculoskeletal disorder or other condition, can cause many other repercussions – including mental health issues.” – Fit for Work

 

Orthopedic Disorders consist of a wide range of problems that are concerned with muscles, ligaments and joints. Disorders are ailments, injuries or diseases that cause knee problems, whiplash, dislocated shoulder, torn cartilages, foot pain and fibromyalgia. The most common forms of orthopedic disorders are arthritis, and back and neck pain.

 

Arthritis is a chronic disease that most commonly affects the joints. Depending on the type of arthritis symptoms may include pain, stiffness, swelling, redness, and decreased range of motion. It affects an estimated 52.5 million adults in the United States. The pain, stiffness, and lack of mobility associate with arthritis produce fatigue and markedly reduce the quality of life of the sufferers.

 

The most common forms of chronic pain are back and neck pain. Low Back Pain is the leading cause of disability worldwide and affects between 6% to 15% of the population. Back and neck pain interferes with daily living and with work, decreasing productivity and creating absences. Arthritis and back pain can have very negative psychological effects and may lead to depression, isolation, and withdrawal from friends and social activities.

 

There are many different treatments for pain, but few are both safe and effective for chronic musculoskeletal pain conditions. So, alternative treatments are needed. Mindfulness practices are effective in treating pain and have been shown to be safe and effective in the management of arthritis, low back pain and neck pain. In addition, mindfulness practices have been shown to improve mental health. So, it is likely that mindfulness practices will be effective for both the physical and mental health issues that accompany musculoskeletal disorders.

 

In today’s Research News article “Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196876/ ), Lorenc and colleagues review and summarize the published research studies on the effectiveness of mindfulness practices for the treatment of the psychological problems that accompany musculoskeletal disorders.

 

They summarize the evidence from 111 published research studies and report that these studies support the effectiveness of yoga for low back pain, and anxiety; Tai Chi for osteoarthritis, depression, anxiety, and sleep disorders; meditation for depression, anxiety, and sleep disorders; and mindfulness for stress and distress. There were no safety problems found with any of these mindfulness techniques.

 

This review indicates that there has accumulated a large body of evidence for the safety and effectiveness of mindfulness practices for the physical and mental health issues that accompany musculoskeletal disorders. Hence the published research to date supports the use of mindfulness practices in the package of treatments for musculoskeletal disorders.

 

So, improve physical and mental health with musculoskeletal disorders with mindfulness practices.

 

“Yoga has been used to alleviate musculoskeletal pain and has been associated with significant improvement in range of motion and function, decreased tenderness, lower levels of depressive symptoms, and decreased pain during activity in patients with musculoskeletal disorders.” – Ruth McCaffrey

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Lorenc, A., Feder, G., MacPherson, H., Little, P., Mercer, S. W., & Sharp, D. (2018). Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions. BMJ open, 8(10), e020222. doi:10.1136/bmjopen-2017-020222

 

Abstract

Objective

To identify potentially effective complementary approaches for musculoskeletal (MSK)–mental health (MH) comorbidity, by synthesising evidence on effectiveness, cost-effectiveness and safety from systematic reviews (SRs).

Design

Scoping review of SRs.

Methods

We searched literature databases, registries and reference lists, and contacted key authors and professional organisations to identify SRs of randomised controlled trials for complementary medicine for MSK or MH. Inclusion criteria were: published after 2004, studying adults, in English and scoring >50% on Assessing the Methodological Quality of Systematic Reviews (AMSTAR); quality appraisal checklist). SRs were synthesised to identify research priorities, based on moderate/good quality evidence, sample size and indication of cost-effectiveness and safety.

Results

We included 84 MSK SRs and 27 MH SRs. Only one focused on MSK–MH comorbidity. Meditative approaches and yoga may improve MH outcomes in MSK populations. Yoga and tai chi had moderate/good evidence for MSK and MH conditions. SRs reported moderate/good quality evidence (any comparator) in a moderate/large population for: low back pain (LBP) (yoga, acupuncture, spinal manipulation/mobilisation, osteopathy), osteoarthritis (OA) (acupuncture, tai chi), neck pain (acupuncture, manipulation/manual therapy), myofascial trigger point pain (acupuncture), depression (mindfulness-based stress reduction (MBSR), meditation, tai chi, relaxation), anxiety (meditation/MBSR, moving meditation, yoga), sleep disorders (meditative/mind–body movement) and stress/distress (mindfulness). The majority of these complementary approaches had some evidence of safety—only three had evidence of harm. There was some evidence of cost-effectiveness for spinal manipulation/mobilisation and acupuncture for LBP, and manual therapy/manipulation for neck pain, but few SRs reviewed cost-effectiveness and many found no data.

Conclusions

Only one SR studied MSK–MH comorbidity. Research priorities for complementary medicine for both MSK and MH (LBP, OA, depression, anxiety and sleep problems) are yoga, mindfulness and tai chi. Despite the large number of SRs and the prevalence of comorbidity, more high-quality, large randomised controlled trials in comorbid populations are needed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196876/

 

Improve Breast Cancer Symptoms with Mindfulness

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Improve Breast Cancer Symptoms with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Results show promise for mindfulness-based interventions to treat common psychological problems such as anxiety, stress, and depression in cancer survivors and to improve overall quality of life.” — Linda E. Carlson

 

Receiving a diagnosis of cancer has a huge impact on most people. Feelings of depression, anxiety, and fear are very common and are normal responses to this life-changing and potentially life-ending experience. But cancer diagnosis is not necessarily a death sentence. Over half of the people diagnosed with cancer are still alive 10 years later and this number is rapidly increasing. But, surviving cancer carries with it a number of problems. Fatigue and insomnia are common symptoms in the aftermath of surviving breast cancer.

 

Mindfulness training has been shown to help with cancer recovery and help to alleviate many of the residual physical and psychological symptoms, including fatigue, stress,  sleep disturbance, and anxiety and depression. One particularly effective mindfulness training program is Mindfulness-Based Stress Reduction (MBSR). The MBSR program consists of 8 weekly 2-hour group sessions involving meditation, yoga, body scan, and discussion. The patients are also encouraged to perform daily practice for 15-45 minutes. The research has been accumulating. It is thus important to take a step back and summarize what has been learned.

 

In today’s Research News article “Mindfulness-Based Stress Reduction on breast cancer symptoms: systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282865/ ), Castanhel and Liberali review, summarize and perform a meta-analysis of the published research studies on the effectiveness of Mindfulness-Based Stress Reduction (MBSR) training for the symptoms of breast cancer patients. They identified 7 published research studies that included a total of 532 women.

 

They report that the literature finds that Mindfulness-Based Stress Reduction (MBSR) training produces a decrease in fatigue in the breast cancer patients. This is significant as fatigue affects all facet of the patient’s life. Additionally, there is no drug treatments which successfully treat fatigue in these patients. This makes MBSR treatment particularly valuable to be included along with the usual treatments.

 

Mindfulness practices, in general have been shown to be effective in relieving fatigue. One of the components of MBSR treatment, yoga practice, has been previously been shown to also relieve fatigue in breast cancer patients. It is possible that this is the critical component of MBSR practice. But it will require further research to determine exactly which components or combinations of components are essential for the relief of fatigue.

 

So, improve breast cancer symptoms with mindfulness.

 

“some of the most difficult elements of the cancer experience are very well-suited to a mindfulness practice. When a person gets diagnosed, there’s fear and uncertainty about the future. There’s the loss of routine and predictability. There’s the physical aspect, the treatment or surgery, pain, insomnia, which almost everybody gets, and the post-treatment fatigue.” — Linda E. Carlson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Castanhel, F. D., & Liberali, R. (2018). Mindfulness-Based Stress Reduction on breast cancer symptoms: systematic review and meta-analysis. Einstein (Sao Paulo, Brazil), 16(4), eRW4383. doi:10.31744/einstein_journal/2018RW4383

 

ABSTRACT

Mindfulness-Based Stress Reduction practices increase the capacity for concentration and attention, and these practices are particularly effective for people with breast cancer. To analyze the effects of the application of Mindfulness-Based Stress Reduction on breast cancer symptoms. Systematic review and meta-analysis were carried out. To find suitable studies, the PubMed/ MEDLINE database was searched using the keywords “breast cancer” and “Mindfulness-Based Stress Reduction”. Studies included were published between 2013 and 2017, written in English and showed methodological quality through the PEDro scale (score greater than 3). They also presented empirical evidence, had an experimental study design (randomized or non-randomized), and had full text available. For the meta-analysis, we used a random-effects model, with standardized mean differences and 95% confidence intervals. Seven studies were included, one non-randomized and containing only an intervention group of Mindfulness-Based Stress Reduction, and six randomized including samples of two or three groups. The non-randomized study showed 6 points on the PEDro scale, the randomized studies of two groups 6 to 7 points and studies with three groups showed 7 points. In the meta-analysis of the two randomized studies, the results, although not significant, revealed a moderate effect for Mindfulness-Based Stress Reduction on the outcome of fatigue, with a mean difference of −0.42 (95%CI −0.92- −0.07; p=0.09). Mindfulness-Based Stress Reduction seems to be a promising alternative for treatment of this disease’s symptoms.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282865/