Stress

Improve Heart Disease with Mindfulness

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Improve Heart Disease with Mindfulness

 

By John M. de Castro, Ph.D.

 

“it is not the stress in our life, but the reaction to stress that is so potentially harmful to our health, including cardiovascular health. Hence, being in a potentially very stressful profession, meditation and relaxation techniques are extremely important and useful to minimize these unhealthy reactions to stress.” – Joon Sup Lee

 

Cardiovascular disease is the number one killer, claiming more lives than all forms of cancer combined. “Heart disease is the leading cause of death for both men and women. About 610,000 people die of heart disease in the United States every year–that’s 1 in every 4 deaths. Every year about 735,000 Americans have a heart attack.” (Centers for Disease Control). A myriad of treatments has been developed for heart disease including a variety of surgical procedures and medications. But the safest effective treatments are lifestyle changes. These include quitting smoking, weight reduction, improved diet, physical activity, and reducing stresses. Cardiac rehabilitation programs for patients recovering from a heart attack, emphasize these lifestyle changes. Unfortunately, for a variety of reasons, 60% of cardiac patients decline participation, making these patients at high risk for another attack.

 

Other safe and effective treatments for cardiovascular disease are contemplative practices, such as meditation, tai chi, and yoga, have also been shown to be helpful for heart health. These practices have also been shown to be helpful for producing the kinds of lifestyle changes needed to prevent heart disease such as smoking cessation, weight reduction, and stress reduction. Although death from heart disease is decreasing in men it is actually increasing in women. So, there is a need to study the effectiveness of mindfulness practice for the treatment of cardiovascular disease in women.

 

In today’s Research News article “Impact of Mindfulness Based Stress Reduction Therapy on Myocardial Function and Endothelial Dysfunction in Female Patients with Microvascular Angina.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762694/ ), Kim and colleagues recruited women who were diagnosed with microvascular angina which is “heart disease that affects the heart’s smallest coronary artery blood vessels. Causes of microvascular angina: Spasms within the walls of these very small arterial blood vessels causes reduced blood flow to the heart muscle leading to a type of chest pain referred to as microvascular angina.” (American Heart Association). The women were provided with an 8-week, 2.5 hour once-a-week program of Mindfulness-Based Stress Reduction (MBSR) which includes of meditation, yoga, and body scan practices and on hour per day of home practice. Participants were measured for heart function and stress parameters before and after the 8-week practice.

 

Kim and colleagues found that following the 8-week MBSR program there was a marked and significant decrease in most stress parameters including somatization, compulsivity, interpersonal sensitivity, depression, anxiety, phobic anxiety, paranoid ideation, and psychoticism. Importantly there were improvements in cardiovascular functions including a decrease in systolic blood pressure and improvements in heart left ventricular function and heart arterial blood vessel function. Additionally, they found that the greater the reduction in the stress parameters the greater the improvements in heart function.

 

Conclusions from this study must be tempered as there wasn’t a comparison group included in the study, only females were examined, and no short- or long-term follow-up was included. But previous research has clearly established that mindfulness training, including MBSR, produces significant reductions in the psychological and physiological responses to stress and improves cardiovascular function. These prior findings combined with the present findings makes the case that MBSR reduces stress response which in turn improves cardiovascular function. This is very important for the promotion of longevity and well being in everyone but particularly for patients with cardiovascular disease.

 

So, improve heart disease with mindfulness,

 

“an analysis of 23 controlled trials into heart disease determined that psychosocial interventions (such as meditation, breathing exercises, and physical relaxation techniques) improved the outcomes when they were added to cardiac rehabilitation programmes for patients with CHD.” – British Heart Foundation

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Bong Joon Kim, In Suk Cho, Kyoung Im Cho. Impact of Mindfulness Based Stress Reduction Therapy on Myocardial Function and Endothelial Dysfunction in Female Patients with Microvascular Angina. J Cardiovasc Ultrasound. 2017 Dec; 25(4): 118–123. Published online 2017 Dec 29. doi: 10.4250/jcu.2017.25.4.118

 

Abstract

Background

Mindfulness-based stress reduction (MBSR) is a structured group program that employs mindfulness meditation to alleviate suffering associated with physical, psychosomatic, and psychiatric disorders. In this study, we investigate the impact of MBSR on left ventricular (LV) and endothelial function in female patients with microvascular angina.

Methods

A total of 34 female patients (mean age 52.2 ± 13.8 years) diagnosed with microvascular angina underwent a MBSR program with anti-anginal medication for 8 weeks. The global longitudinal strain (GLS) of the LV was used as a parameter to assess myocardial function and reactive brachial flow-mediated dilatation (FMD) was used to assess endothelial function. Symptoms were analyzed by the Symptom Checklist 90 Revised to determine emotional stress. Changes in GLS and FMD between baseline and post-MBSR were analyzed.

Results

After 8 weeks of programmed MBSR treatment, stress parameters were significantly decreased. In addition, GLS (−19.5 ± 2.1% vs. −16.6 ± 2.5%, p < 0.001) and reactive FMD significantly improved (8.9 ± 3.0% vs. 6.9 ± 2.6%, p = 0.005) after MBSR compared to baseline. The changes in GLS correlated to changes in FMD (r = 0.120, p = 0.340) and with the changes in most stress parameters.

Conclusion

MBSR has beneficial impacts on myocardial and endothelial function in female patients with microvascular angina.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762694/

 

Reduce Responsiveness to Social Evaluative Threat with Mindfulness

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Reduce Responsiveness to Social Evaluative Threat with Mindfulness

 

By John M. de Castro, Ph.D.

 

“You can’t judge yourself or worry about what the other person is thinking if you’re too busy experiencing the wonder of the here and now.” – Jonathan Hinek

 

Humans are social creatures. All that the species has accomplished resulted from its ability to work together and build upon the work of others. Social connections are crucial to our health and happiness. Hence, it is very important for the individual to have effective satisfying social relationships. Unfortunately, interacting with other people is extremely complex and many find it very difficult to effectively engage with others. It is a common human phenomenon that being in a social situation can be stressful and anxiety producing. This is particularly true when asked to perform in a social context such as giving a speech. In fact, research has demonstrated that people are more afraid of public speaking than they are of death.

 

Mindfulness in general appears to improve social relationships. In today’s Research News article “Trait Mindfulness Modulates Neuroendocrine and Affective Responses to Social Evaluative Threat.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087919/ ), Brown and colleagues investigate the relationship of mindfulness with social anxiety. They recruited college students and randomly assigned them to either a social anxiety or control condition. The students performed a Trier Social Stress Test involving preparing and giving a 5-minute speech and doing simple math either in front of critical peer evaluators (social anxiety) or alone (control). Before and after the test the students provided saliva samples to assess cortisol levels, an indicator of stress. They were also measured for anxiety, negative emotions, fear of evaluation, and mindfulness.

 

They found that the social anxiety manipulation compared to the control condition produced a significant elevation of salivary cortisol and anxiety. But, mindfulness moderated the effects such that students high in mindfulness had significantly lower anxiety, negative emotions, and cortisol responses to the social anxiety test than students low in mindfulness. This was true even when the students’ levels of fear of evaluation were controlled for. On the other hand, there were no significant effects of mindfulness in the control condition. So, the mindfulness effects were only with social anxiety.

 

These results suggest that mindfulness buffers the response to social stress and is associated with lower levels of stress hormones and negative emotions when exposed to social evaluative stress. These results, however, are correlational. So, causation cannot be determined within this study. But other research has demonstrated that mindfulness produces lower levels of stress, negative emotions, and anxiety and better social performance. So, it is likely that the results from the present study are indicative of mindfulness lowering social anxiety.

 

So, reduce responsiveness to social evaluative threat with mindfulness.

 

“Mindfulness meditation starts with observing an experience without trying to change or control it. It’s a practice in accepting reality and minimizing your resistance to it. This means to stop judging social interactions with negative adjectives, such as, scary, intimidating, uncomfortable, embarrassing, and so on.” – Adam Rockman

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Brown, K. W., Weinstein, N., & Creswell, J. D. (2012). Trait Mindfulness Modulates Neuroendocrine and Affective Responses to Social Evaluative Threat. Psychoneuroendocrinology, 37(12), 2037–2041. http://doi.org/10.1016/j.psyneuen.2012.04.003

 

Abstract

Background

Individual differences in mindfulness have been associated with numerous self-report indicators of stress, but research has not examined how mindfulness may buffer neuroendocrine and psychological stress responses under controlled laboratory conditions. The present study investigated the role of trait mindfulness in buffering cortisol and affective responses to a social evaluative stress challenge versus a control task.

Methods

Participants completed measures of trait mindfulness, perceived stress, anxiety, and fear of negative evaluation before being randomized to complete the Trier Social Stress Test (TSST; Kirschbaum et al., 1993) or a control task. At points throughout the session, participants provided five saliva samples to assess cortisol response patterns, and completed four self-report measures of anxiety and negative affect to assess psychological responses.

Results

In accord with hypotheses, higher trait mindfulness predicted lower cortisol responses to the TSST, relative to the control task, as well as lower anxiety and negative affect. These relations remained significant when controlling for the role of other variables that predicted cortisol and affective responses.

Conclusions

The findings suggest that trait mindfulness modulates cortisol and affective responses to an acute social stressor. Further research is needed to understand the neural pathways through which mindfulness impacts these responses.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087919/

Improve Employee Mental Health with Internet-Based Mindfulness Training

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Improve Employee Mental Health with Internet-Based Mindfulness Training

 

By John M. de Castro, Ph.D.

 

“Mindfulness can only attain sustainable success in the business world if its benefits are optimized and its risks minimized. Participants in mindfulness practices in the workplace must engage voluntarily and proactively if their endeavors are to bear fruit.” – David Brendel

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. How we spend that time is immensely important for our psychological and physical health. Indeed, the work environment has even become an important part of our social lives, with friendships and leisure time activities often attached to the work environment. But, more than half of employees in the U.S. and nearly 2/3 worldwide are unhappy at work. This is partially due to work-related stress which is epidemic in the western workplace. Almost two thirds of workers reporting high levels of stress at work. This stress can result in impaired physical and mental health and can result in burnout; producing fatigue, cynicism, and professional inefficacy.

 

To help overcome unhappiness, stress, and burnout, mindfulness practices have been implemented in the workplace. Indeed, mindfulness practices have been shown to markedly reduce the physiological and psychological responses to stress. As a result, it has become very trendy for business to incorporate meditation into the workday to help improve employee well-being, health, and productivity. Devoting time during the busy workday can be difficult. Mindfulness training over the internet is an alternative training for people who find face-to-face training difficult and inconvenient. Online mindfulness training has shown great promise with effectiveness equivalent to face-to-face training.

 

In today’s Research News article “Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739441/ ), Stratton and colleagues review, summarize, and perform a meta-analysis of the effectiveness of employee health mental programs implemented over the internet (E-Health Programs) to reduce symptoms of depression, anxiety, and/or stress. They identified 22 randomized controlled trials, with 11 employing Cognitive Behavioral Therapy (CBT), 6 employing stress reduction programs, and 6 employing mindfulness-based interventions.

 

They found that the Cognitive Behavioral Therapy (CBT) and the stress reduction programs were significantly effective in improving depression, anxiety, and/or stress in the workers, but the effect sizes were small to moderate. On the other hand, the mindfulness-based interventions produced large significant reductions in depression, anxiety, and/or stress. The effect sizes for mindfulness-based interventions were significantly larger than those for CBT or stress reduction programs.

 

The results suggest that programs implemented over the internet and designed to improve mental health in workers are effective in improving depression, anxiety, and/or stress. The results further suggest that mindfulness-based programs are significantly more effective. Mindfulness training has been frequently demonstrated to reduce depression, anxiety, and/or stress in general or clinical populations. So, it’s ability to do so here is not surprising but suggests that it is also effective when delivered over the internet. This is important as internet delivery does not detract from workplace time, is convenient for the employees, and is relatively inexpensive for the employer to implement.

 

So, improve employee mental health with internet-based mindfulness training.

 

“injecting a corporate culture of mindfulness not only improves focus, but the ability to manage stress and how employees work together.” – Science Daily

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Elizabeth Stratton, Amit Lampit, Isabella Choi, Rafael A. Calvo, Samuel B. Harvey, Nicholas Glozier. Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis. PLoS One. 2017; 12(12): e0189904. Published online 2017 Dec 21. doi: 10.1371/journal.pone.0189904

 

Abstract

Background

Many organisations promote eHealth applications as a feasible, low-cost method of addressing mental ill-health and stress amongst their employees. However, there are good reasons why the efficacy identified in clinical or other samples may not generalize to employees, and many Apps are being developed specifically for this group. The aim of this paper is to conduct the first comprehensive systematic review and meta-analysis evaluating the evidence for the effectiveness and examine the relative efficacy of different types of eHealth interventions for employees.

Methods

Systematic searches were conducted for relevant articles published from 1975 until November 17, 2016, of trials of eHealth mental health interventions (App or web-based) focused on the mental health of employees. The quality and bias of all identified studies was assessed. We extracted means and standard deviations from published reports, comparing the difference in effect sizes (Hedge’s g) in standardized mental health outcomes. We meta-analysed these using a random effects model, stratified by length of follow up, intervention type, and whether the intervention was universal (unselected) or targeted to selected groups e.g. “stressed”.

Results

23 controlled trials of eHealth interventions were identified which overall suggested a small positive effect at both post intervention (g = 0.24, 95% CI 0.13 to 0.35) and follow up (g = 0.23, 95% CI 0.03 to 0.42). There were differential short term effects seen between the intervention types whereby Mindfulness based interventions (g = 0.60, 95% CI 0.34 to 0.85, n = 6) showed larger effects than the Cognitive Behaviour Therapy (CBT) based (g = 0.15, 95% CI 0.02 to 0.29, n = 11) and Stress Management based (g = 0.17, 95%CI -0.01 to 0.34, n = 6) interventions. The Stress Management interventions however differed by whether delivered to universal or targeted groups with a moderately large effect size at both post-intervention (g = 0.64, 95% CI 0.54 to 0.85) and follow-up (g = 0.69, 95% CI 0.06 to 1.33) in targeted groups, but no effect in unselected groups.

Interpretation

There is reasonable evidence that eHealth interventions delivered to employees may reduce mental health and stress symptoms post intervention and still have a benefit, although reduced at follow-up. Despite the enthusiasm in the corporate world for such approaches, employers and other organisations should be aware not all such interventions are equal, many lack evidence, and achieving the best outcomes depends upon providing the right type of intervention to the correct population.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739441/

Reduce Stress and Improve Cardiovascular Function with Slow Yogic Breathing

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Reduce Stress and Improve Cardiovascular Function with Slow Yogic Breathing

 

By John M. de Castro, Ph.D.

 

“Shallow breathing over time can contribute to feelings of depression, stress, and anxiety. Becoming aware of your breath through targeted yoga breathing exercises can prevent many of these issues from developing within the body.” – Yoga U

 

Stress is an integral part of life. In fact, I’ve quipped that the definition of death is when stress ceases. People often think of stress as a bad thing. But, it is in fact essential to the health of the body. In fact, we invest time and resources in stressing ourselves, e.g ridding rollercoasters, sky diving, competing in sports, etc. We say we love a challenge, but, challenges are all stressful. So, we actually love to stress ourselves. In moderation, it is healthful and provides interest and fun to life. If stress, is high or is prolonged, however, it can be problematic. It can damage our physical and mental health and even reduce our longevity, leading to premature deaths. So, it is important that we develop methods to either reduce or control high or prolonged stress or reduce our responses to it.

 

Mindfulness practices, including yoga practice, have been found routinely to reduce the psychological and physiological responses to stress. Yoga, however, consists of a number of components including, poses, breathing exercises, meditation, concentration, and philosophy/ethics.  So, it is difficult to determine which facet or combination of facets of yoga are responsible for which benefit. Alternate nostril yoga breathing is a regulated breathing alternating between the left and right nostril. Breathing through each nostril is thought to affect its respective hemisphere in the brain producing differential effects.

 

In today’s Research News article “. Effect of Modified Slow Breathing Exercise on Perceived Stress and Basal Cardiovascular Parameters.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769199/ ), Naik and colleagues examine the slow alternate nostril breathing practice of yoga and its effectiveness for stress reduction. They recruited health males, 18-30 years of age, and randomly assigned them to either 30-minutes in the morning, 5-times per week for 12 weeks slow alternate nostril breathing practice or a no-treatment control conditions. The were measured before and after the 12-week practice period for perceived stress, body size, heart rate, and systolic and diastolic blood pressure.

 

They found that after the 12-weeks of slow alternate nostril breathing practice there were significant reductions in perceived stress, heart rate, and systolic and diastolic blood pressure.

Hence, the practice appeared to reduce stress effects and relax the cardiovascular system. These results should provide the encouragement for a larger randomized controlled trial which includes a comparison to other components of yoga practice, e.g. relaxation, postures, meditation, to determine which components are most effective in combating stress. Regardless, the results are encouraging and suggest that slow alternate nostril breathing practice is effective in reducing psychological and physiological responses to stress.

 

So, reduce stress and improve cardiovascular function with slow yogic breathing.

 

“Yoga breathing can help you achieve balance in both your body and mind. In fact, researchers have found that regularly practicing yoga breathing can have the following benefits: reduce anxiety and depression, lower and/or stabilize blood pressure, increase energy levels, relax muscles, and decrease feelings of stress and being overwhelmed.” – Lung Institute

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

  1. Sunil Naik, G.S. Gaur, G.K. Pal. Effect of Modified Slow Breathing Exercise on Perceived Stress and Basal Cardiovascular Parameters. Int J Yoga. 2018 Jan-Apr; 11(1): 53–58. doi: 10.4103/ijoy.IJOY_41_16

 

Abstract

Context:

Different types of breathing exercises have varied effects on cardiovascular parameters and the stress levels in an individual.

Aim:

The aim of this study was to assess the effect of a modified form of isolated alternate nostril, slow breathing exercise on perceived stress, and cardiovascular parameters in young, male volunteers.

Settings and Design:

This was a randomized control study carried out at Advanced Centre for Yoga Therapy Education and Research, Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry in 2014.

Subjects and Methods:

Hundred healthy male volunteers were randomized into control group, n = 50 and slow breathing group (study), n = 50. Slow breathing exercise training was given to study group for 30 min a day, 5 times/week for 12 weeks, under the supervision of certified yoga trainers. Perceived Stress Scale (PSS) using Cohen’s questionnaire, anthropometric parameters such as body mass index (BMI), waist-hip ratio (WHR), and cardiovascular parameters such as heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were recorded at baseline and after 12 weeks. The control group did not receive any intervention. Slow breathing exercise training was provided for the study group. During the study period, one volunteer opted out of the study group due to personal reasons.

Results:

HR, SBP, DBP, and PSS decreased significantly (P < 0.05) in the study group following 12 weeks slow breathing exercise training, while no significant change (P > 0.05) was observed in BMI and WHR. There was no significant change in the control group.

Conclusion:

Twelve weeks of modified slow breathing exercise reduced perceived stress and improved the cardiovascular parameters. The above results indicate that our modified slow breathing exercise is effective in reducing stress and improving the cardiovascular parameters.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769199/

Improve Cardiovascular State and Stress with Yogic Breathing

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Improve Cardiovascular State and Stress with Yogic Breathing

 

By John M. de Castro, Ph.D.

 

“Yoga breathing can help you achieve balance in both your body and mind. In fact, researchers have found that regularly practicing yoga breathing can have the following benefits: reduce anxiety and depression, lower and/or stabilize blood pressure, increase energy levels, relax muscles, and decrease feelings of stress and being overwhelmed.” – Lung Institute

 

Yoga practice is becoming increasingly popular in the west, for good reason. It has documented benefits for the individual’s psychological and physical health and well-being. It has also been shown to have cognitive benefits, improving memory. Yoga, however, consists of a number of components including, poses, breathing exercises, meditation, concentration, and philosophy/ethics.  So, it is difficult to determine which facet or combination of facets of yoga are responsible for which benefit. Hence, it is important to begin to test each component in isolation to determine its effects. This would allow for optimization of yoga practice for specific problems.

 

In today’s Research News article “Effect of modified slow breathing exercise on perceived stress and basal cardiovascular parameters.” (See summary below or view the full text of the study at: http://www.ijoy.org.in/article.asp?issn=0973-6131;year=2018;volume=11;issue=1;spage=53;epage=58;aulast=Naik ), Naik and colleagues examined the effects of yogic breathing techniques on cardiovascular performance. They recruited healthy adult male volunteers (age 18 to 30 years) and randomly assigned them to a no-treatment control group or to receive 12 weeks, 5 days per week, 30 minutes per day of yogic slow (6 second inhale and 6 second exhale) alternate nostril breathing. The participants were also encouraged to practice at home daily. They were measured before and after the 12-week training period for body size, perceived stress, resting heart rate, systolic blood pressure, and diastolic blood pressure.

 

They found that after training the yogic breathing group had a significant reduction in resting heart rate, and systolic and diastolic blood pressure. They also observed a particularly large significant reduction in perceived stress in the yogic breathing group. There were no significant changes in body size observed. Hence, the breath training in yoga appears to have important benefits for cardiovascular function and the stress levels of the practitioners.

 

It can be speculated that the reductions in stress were responsible for the improvements in cardiovascular performance as stress is well known to increase heart rate and blood pressure. In this study, however, causation cannot be determined. The lack of an active control condition is a weakness of the study allowing for bias to be an alternative explanation for the results. In addition, the lack of a follow-up measurement did not allow for a determination of the duration of effectiveness of the technique. Future research should include women, an active control, and long-term follow-up measurements. Regardless, yogic slow alternate nostril breathing would appear to be a promising method to reduce stress and promote cardiovascular health.

 

So, improve cardiovascular state and stress with yogic breathing.

 

“Physiology and psychology are two ends of the same stick. You can’t work on one without the other.” Nowhere is this truer than with conscious breathing, which acts as a medicinal tool, increasing well-being and peace of mind.” – Angela Wilson,

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Naik G S, Gaur G S, Pal G K. Effect of modified slow breathing exercise on perceived stress and basal cardiovascular parameters. Int J Yoga 2018;11:53-8

 

Context: Different types of breathing exercises have varied effects on cardiovascular parameters and the stress levels in an individual. Aim:The aim of this study was to assess the effect of a modified form of isolated alternate nostril, slow breathing exercise on perceived stress, and cardiovascular parameters in young, male volunteers. Settings and Design: This was a randomized control study carried out at Advanced Centre for Yoga Therapy Education and Research, Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry in 2014. Subjects and Methods: Hundred healthy male volunteers were randomized into control group, n = 50 and slow breathing group (study), n = 50. Slow breathing exercise training was given to study group for 30 min a day, 5 times/week for 12 weeks, under the supervision of certified yoga trainers. Perceived Stress Scale (PSS) using Cohen’s questionnaire, anthropometric parameters such as body mass index (BMI), waist-hip ratio (WHR), and cardiovascular parameters such as heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were recorded at baseline and after 12 weeks. The control group did not receive any intervention. Slow breathing exercise training was provided for the study group. During the study period, one volunteer opted out of the study group due to personal reasons. Results: HR, SBP, DBP, and PSS decreased significantly (P < 0.05) in the study group following 12 weeks slow breathing exercise training, while no significant change (P > 0.05) was observed in BMI and WHR. There was no significant change in the control group. Conclusion: Twelve weeks of modified slow breathing exercise reduced perceived stress and improved the cardiovascular parameters. The above results indicate that our modified slow breathing exercise is effective in reducing stress and improving the cardiovascular parameters.

http://www.ijoy.org.in/article.asp?issn=0973-6131;year=2018;volume=11;issue=1;spage=53;epage=58;aulast=Naik

Improve Psychological Well-Being in the Elderly with Mild Memory Loss with Meditation

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Improve Psychological Well-Being in the Elderly with Mild Memory Loss with Meditation

 

By John M. de Castro, Ph.D.

 

“Wouldn’t it be wonderful if all the answers we’re looking for when it comes to ending memory loss could be gained by simply doing KK for 12 minutes each morning? Perhaps that magic bullet is already here, waiting to be discovered in each and every one of us after all. Now, wouldn’t that be grand?” – Dharma Singh Khalsa

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. It cannot be avoided. Our mental abilities may also decline with age including impairments in memory, attention, and problem solving ability. These are called age related cognitive decline. This occurs to everyone as they age, but to varying degrees. Some deteriorate into a dementia, while others maintain high levels of cognitive capacity into very advanced ages. It is estimated that around 30% of the elderly show significant age related cognitive decline. These cognitive declines markedly increase the risk of dementia or Alzheimer’s Disease. The declines occur along with sleep disruptions declines in mental health and quality of life, which in turn, appear to exacerbate the decline.

 

There is some hope, however, for those who are prone to deterioration as there is evidence that these cognitive declines can be slowed. For example, a healthy diet and a regular program of exercise can slow the physical decline of the body with aging. Also, contemplative practices such as meditation, yoga, and tai chi or qigong have all been shown to be beneficial in slowing or delaying physical and mental decline with aging. Indeed, mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue.

 

In today’s Research News article “Effects of Meditation versus Music Listening on Perceived Stress, Mood, Sleep, and Quality of Life in Adults with Early Memory Loss: A Pilot Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649740/ ), Innes and colleagues recruited community living adults over 50 years of age and experiencing memory problems and slight cognitive decline. They were randomly assigned to 12-week, 12 minutes per day, programs of classical music listening or Kirtan Kriya meditation, performed while sitting comfortably with eyes closed. At the first session the participants received 35-minute instruction on relaxation and their specific program and then provided DVDs for daily home practice. Kirtan Kriya meditation included signing a mantra, successive finger touching and visualization exercises. After the 12 weeks of practice participants were free to continue practicing if they wished. They were measured before and after the 12-week programs and 14 weeks later for body size, sleep quality, perceived stress, health-related quality of life, psychological well-being, mood, memory, and cognitive performance.

 

Retention and participation were high, with 92% of the music listening participants and 88% of the meditation participants completing the program. Participants completed 93% of the required session and 73% of the optional sessions during the second 14-week period. This indicates that the participants found the programs enjoyable and worth their time and effort.

 

Over the 12-week program, both groups showed significant improvements in sleep quality, perceived stress, health-related quality of life, psychological well-being, and mood. These improvements were either sustained or further improved over the subsequent 14 weeks. The meditation group had significantly greater improvements than the music listening group in perceived stress, mood, psychological well-being, and mental health quality of life. In addition, the greater the improvements in mood, stress, sleep, well-being, and quality of life, the greater the improvements in memory function. Hence, the two forms of relaxation produced improvements in the participants well-being which were related to improvements in memory. But, meditation had a greater impact then music listening.

 

These results are quite remarkable that such simple practices for only 12 minutes per day can have such profound effects on the well-being of aging individuals with slight cognitive decline. This could potentially delay of lower the likelihood that the decline will continue into dementia of Alzheimer’s Disease. It is important that the effects were lasting and participation high, both of which suggest that the meditation program can be easily and inexpensively applied to large groups of community-based aging individuals.

 

So, improve psychological well-being in the elderly with mild memory loss with meditation

 

“Mild cognitive impairment (MCI) can affect up to 20% of the population at any one time—and half of them will progress to full-on dementia. Now, a recent study . . .  finds as little as 15 minutes of daily meditation can significantly slow that progression.” – Nina Elias

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Innes, K. E., Selfe, T. K., Khalsa, D. S., & Kandati, S. (2016). Effects of Meditation versus Music Listening on Perceived Stress, Mood, Sleep, and Quality of Life in Adults with Early Memory Loss: A Pilot Randomized Controlled Trial. Journal of Alzheimer’s Disease : JAD, 52(4), 1277–1298. http://doi.org/10.3233/JAD-151106

 

Abstract

Background

Older adults with subjective cognitive decline (SCD) are at increased risk not only for Alzheimer’s disease, but for poor mental health, impaired sleep, and diminished quality of life (QOL), which in turn, contribute to further cognitive decline, highlighting the need for early intervention.

Objective

In this randomized controlled trial, we assessed the effects of two 12-week relaxation programs, Kirtan Kriya Meditation (KK) and music listening (ML), on perceived stress, sleep, mood, and health-related QOL in older adults with SCD.

Methods

Sixty community-dwelling older adults with SCD were randomized to a KK or ML program and asked to practice 12 minutes daily for 12 weeks, then at their discretion for the following 3 months. At baseline, 12 weeks, and 26 weeks, perceived stress, mood, psychological well-being, sleep quality, and health-related QOL were measured using well-validated instruments.

Results

Fifty-three participants (88%) completed the 6-month study. Participants in both groups showed significant improvement at 12 weeks in psychological well-being and in multiple domains of mood and sleep quality (p’s ≤ 0.05). Relative to ML, those assigned to KK showed greater gains in perceived stress, mood, psychological well-being, and QOL-Mental Health (p’s ≤ 0.09). Observed gains were sustained or improved at 6 months, with both groups showing marked and significant improvement in all outcomes. Changes were unrelated to treatment expectancies.

Conclusions

Findings suggest that practice of a simple meditation or ML program may improve stress, mood, well-being, sleep, and QOL in adults with SCD, with benefits sustained at 6 months and gains that were particularly pronounced in the KK group.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649740/

Decrease Stress and Improve Academic Performance with Mindfulness

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Decrease Stress and Improve Academic Performance with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Those higher in mindfulness experienced less anxiety associated with high-pressure math tests, and this in turn was linked with improved performance.” – Matthew Brensilver

 

In the modern world education is a key for success. Where a high school education was sufficient in previous generations, a college degree is now required to succeed in the new knowledge based economies. There is a lot of pressure on students to excel so that they can be admitted to the best universities and there is a lot of pressure on university students to excel so that they can get the best jobs after graduation. As a result, parents and students are constantly looking for ways to improve student performance in school.

 

The primary tactic has been to pressure the student and clear away routine tasks and chores so that the student can focus on their studies. But, this might in fact be counterproductive as the increased pressure can actually lead to stress and anxiety which can impede performance. A better tactic may be the development of mindfulness skills with contemplative practices. These practices and high levels of mindfulness have been shown to be helpful in coping with the school environment and for the performance of both students and teachers. So, perhaps, mindfulness training may provide the needed edge in college academic performance.

 

In today’s Research News article “A Randomized Controlled Pilot Intervention Study of a Mindfulness-Based Self-Leadership Training (MBSLT) on Stress and Performance.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605596/, Sampl and colleagues recruited college students and randomly assigned them to either receive a 10-week Mindfulness-Based Self-Leadership Training (MBSLT) program or a wait-list control condition.  MBSLT was administered once a week for 2 hours. In addition to mindfulness training MBSLT trained students in self-goal setting, self-reward, self-observation, self-cueing and reminding, visualizing successful performances, self-talk, and evaluating beliefs and assumption. The participants were also given exercises to be practiced at home. All participants were measured before and after training for mindfulness, self-leadership, perceived stress, test anxiety, self-efficacy, semester grades, and Grade Point Average (GPA).

 

They found that at the conclusion of training the Mindfulness-Based Self-Leadership Training (MBSLT) group had significantly greater mindfulness, self-efficacy, and self-leadership and significantly lower levels of perceived stress and test anxiety. Importantly, the MBSLT group had significantly 24% higher grades at the end of the semester than the control group. Hence, mindfulness training improved the student’s mental health and academic performance.

These results are interesting and important and replicate prior research findings that mindfulness reduces stress and anxiety, including test anxiety and improves self-efficacy and academic performance. The present study supplemented mindfulness training with self-leadership training. Since there was not a mindfulness only or a self-leadership training only condition, it cannot be determined whether each component alone or in combination produced the benefits. In addition, they did not perform a mediation analysis to determine if the improvements in the students’ psychological condition was responsible for the improved academic performance.

 

Regardless, it is clear that the Mindfulness-Based Self-Leadership Training (MBSLT) training produced significant improvements in the students’ mental condition and academic performance. The magnitude of the increase in grades was striking and suggests that the mindfulness training may be important for college students to allow them to improve their psychological outlook and in turn reach their full academic potential.

 

So, decrease stress and improve academic performance with mindfulness.

 

“cultivating mindfulness is an effective and efficient technique for improving cognitive function, with widereaching consequences.” – Michael Mrazek

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Sampl, J., Maran, T., & Furtner, M. R. (2017). A Randomized Controlled Pilot Intervention Study of a Mindfulness-Based Self-Leadership Training (MBSLT) on Stress and Performance. Mindfulness, 8(5), 1393–1407. http://doi.org/10.1007/s12671-017-0715-0

 

Abstract

The present randomized pilot intervention study examines the effects of a mindfulness-based self-leadership training (MBSLT) specifically developed for academic achievement situations. Both mindfulness and self-leadership have a strong self-regulatory focus and are helpful in terms of stress resilience and performance enhancements. Based on several theoretical points of contact and a specific interplay between mindfulness and self-leadership, the authors developed an innovative intervention program that improves mood as well as performance in a real academic setting. The intervention was conducted as a randomized controlled study over 10 weeks. The purpose was to analyze the effects on perceived stress, test anxiety, academic self-efficacy, and the performance of students by comparing an intervention and control group (n = 109). Findings demonstrated significant effects on mindfulness, self-leadership, academic self-efficacy, and academic performance improvements in the intervention group. Results showed that the intervention group reached significantly better grade point averages than the control group. Moreover, the MBSLT over time led to a reduction of test anxiety in the intervention group compared to the control group. Furthermore, while participants of the control group showed an increase in stress over time, participants of the intervention group maintained constant stress levels over time. The combination of mindfulness and self-leadership addressed both positive effects on moods and on objective academic performance. The effects demonstrate the great potential of combining mindfulness with self-leadership to develop a healthy self-regulatory way of attaining achievement-related goals and succeeding in high-stress academic environments.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605596/

Protect the Aging Brain with Meditation

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Protect the Aging Brain with Meditation

 

By John M. de Castro, Ph.D.

 

“long-term engagement in mindfulness meditation may enhance cognitive performance in older adults, and that with persistent practice, these benefits may be sustained. That’s great news for the millions of aging adults working to combat the negative effects of aging on the brain.” B. Grace Bullock

 

Human life is one of constant change. We revel in our increases in physical and mental capacities during development, but regret their decreases during aging. The aging process involves a systematic progressive decline in every system in the body, the brain included. Starting in the 20s there is a progressive decrease in the volume of the brain as we age.

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity.  Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread area. and have found that meditation practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. In addition, they have been able to investigate various techniques that might slow the process of neurodegeneration that accompanies normal aging. They’ve found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation and yoga have been found to degenerate less with aging than non-practitioners.

 

In today’s Research News article “Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447722/, Kurth and colleagues review and summarize the published research literature on the neuroprotective effects of meditation in the elderly. They discuss the ideas that the aging based deterioration of the brain is due to a number of processes, including changes in the DNA telomeres, inflammation, stress, and neuroplasticity and that meditation appears to effect all of these processes.

 

There has accumulated evidence that meditation protects against age related decline at the molecular genetic level. As we age the length of a DNA structures called the telomeres progressively shorten. It is thought that the shorter the telomeres get the more difficult it becomes for cells to replicate properly and thus leads to decline. Mindfulness training in general and meditation specifically, has been shown to reduce the shortening of the telomeres with aging. Kurth and colleagues speculate that this is one mechanism by which meditation protects the brain from age related decline.

 

As we age the natural inflammatory response that normally occurs to protect against infection begins to increase in general and lose its specificity to fighting particular diseases, pathogens, and injuries. It becomes more widespread damaging normal tissues. Mindfulness training in general and meditation specifically has been shown to reduce inflammatory responses. It seems reasonable that this is another mechanism by which meditation protects the body from age related decline.

 

Stress is present throughout life. But if it is too intense or prolonged the biological responses to stress begin to damage the body. These stress induced changes are similar to age related deterioration. Stress effects may accumulate over time. Hence, the older we get the greater the total stress induced damage. Mindfulness training in general and meditation specifically has been shown to improve emotion regulation and to reduce the physiological and psychological responses to stress. This is hypothesized to be another mechanism by which meditation protects the brain from deterioration with aging.

 

Neuroplasticity is a change in the size and connectivity of brain structures as they are exercised over a prolonged period of time. Mindfulness training in general and meditation specifically has been shown to produce neuroplastic changes in the brain, increasing the size and connectivity of brain structures. This process would tend to counteract brain degeneration with aging and may be another mechanism by which meditation protects the brain during aging.

 

Hence there has accumulated evidence that meditation reduces the deterioration of the brain with aging. It appears to do so by altering a number of different mechanisms including changes in the DNA telomeres, inflammation, stress, and neuroplasticity. This protection of the brain may be responsible to the ability of meditation to reduce the decline in mental abilities that occur with aging. This would tend to make aging a more benign process.

 

So, protect the aging brain with meditation.

 

We expected rather small and distinct effects located in some of the regions that had previously been associated with meditating. Instead, what we actually observed was a widespread effect of meditation that encompassed regions throughout the entire brain.” – Florian Kurth

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kurth, F., Cherbuin, N., & Luders, E. (2017). Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field. Frontiers in Psychology, 8, 860. http://doi.org/10.3389/fpsyg.2017.00860

 

Abstract

Over the last decade, an increasing number of studies has reported a positive impact of meditation on cerebral aging. However, the underlying mechanisms for these seemingly brain-protecting effects are not well-understood. This may be due to the fact, at least partly, that systematic empirical meditation research has emerged only recently as a field of scientific scrutiny. Thus, on the one hand, critical questions remain largely unanswered; and on the other hand, outcomes of existing research require better integration to build a more comprehensive and holistic picture. In this article, we first review theories and mechanisms pertaining to normal (brain) aging, specifically focusing on telomeres, inflammation, stress regulation, and macroscopic brain anatomy. Then, we summarize existing research integrating the developing evidence suggesting that meditation exerts positive effects on (brain) aging, while carefully discussing possible mechanisms through which these effects may be mediated.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447722/

Reduce Stress with Yoga

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Reduce Stress with Yoga

 

By John M. de Castro, Ph.D.

 

“Yoga helps us slow down for a moment and tune into the breath. Simply the focus on one thing — which is the very definition of meditation — allows us to decompress.” – Terri Kennedy

 

Stress is an integral part of life. In fact, I’ve quipped that the definition of death is when stress ceases. People often think of stress as a bad thing. But, it is in fact essential to the health of the body. If the muscles are not stressed to some extent they deteriorate. As it turns out, this is also true for the brain. The same goes for our psychological health. If we don’t have any stress, we call it boredom. In fact, we invest time and resources in stressing ourselves, e.g ridding rollercoasters, sky diving, competing in sports, etc. We say we love a challenge, but, challenges are all stressful. So, we actually love to stress ourselves. In moderation, it is healthful and provides interest and fun to life.

 

If stress, is high or is prolonged, however, it can be problematic. It can damage our physical and mental health and even reduce our longevity, leading to premature deaths. So, it is important that we develop methods to either reduce or control high or prolonged stress or reduce our responses to it. Mindfulness practices have been found routinely to reduce the psychological and physiological responses to stress. A physiological indicator of stress is the levels of the hormone Cortisol in the blood. Mindfulness training has been shown to reduce cortisol levels. But, it is not known what types of mindfulness training techniques are effective and which may be less so. Hence, it makes sense to test the effectiveness of yoga practice to reduce perceived stress and responsiveness to stress as measured by Cortisol levels.

 

In today’s Research News article “Longitudinal and Immediate Effect of Kundalini Yoga on Salivary Levels of Cortisol and Activity of Alpha-Amylase and Its Effect on Perceived Stress.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433116/, García-Sesnich and colleagues recruited college students participating in in a 3-month Kundalini Yoga class and a comparable group of college students who were not participating. They were measured before and after the 3-month practice period for perceived stress and saliva samples were obtained to measure cortisol and α-amylase levels, markers of stress.

 

They found that following the 3-month intervention period, compared to the baseline and control group the yoga group had a significant decrease in perceived stress but there were no significant differences for either cortisol and α-amylase levels. Hence the yoga program decreased the psychological but not the physical markers of stress. It is not clear as to why they failed to detect an effect of yoga practice on cortisol and α-amylase levels as previous research has shown significant reductions after yoga practice. It is possible that the small sample size did not provide sufficient statistical power to detect a significant change. Regardless, yoga practice was demonstrated to produce improvements in perceived stress in college students, a group that is generally highly stressed.

 

So, reduce stress with yoga.

 

“Meditation is an incredibly powerful tool for relaxing and slowing down the mind as is any kind of breath awareness. Whether you’re holding postures, flowing through sequences, or in a seated meditation pose, everything begins to focus and slow down when you take your awareness to the breath. Over time and with repeated practice, you start to develop new habits towards a more relaxed internal state.” – Anna Coventry

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

García-Sesnich, J. N., Flores, M. G., Ríos, M. H., & Aravena, J. G. (2017). Longitudinal and Immediate Effect of Kundalini Yoga on Salivary Levels of Cortisol and Activity of Alpha-Amylase and Its Effect on Perceived Stress. International Journal of Yoga, 10(2), 73–80. http://doi.org/10.4103/ijoy.IJOY_45_16

 

Abstract

Context:

Stress is defined as an alteration of an organism’s balance in response to a demand perceived from the environment. Diverse methods exist to evaluate physiological response. A noninvasive method is salivary measurement of cortisol and alpha-amylase. A growing body of evidence suggests that the regular practice of Yoga would be an effective treatment for stress.

Aims:

To determine the Kundalini Yoga (KY) effect, immediate and after 3 months of regular practice, on the perception of psychological stress and the salivary levels of cortisol and alpha-amylase activity.

Settings and Design:

To determine the psychological perceived stress, levels of cortisol and alpha-amylase activity in saliva, and compare between the participants to KY classes performed for 3 months and a group that does not practice any type of yoga.

Subjects and Methods:

The total sample consisted of 26 people between 18 and 45-year-old; 13 taking part in KY classes given at the Faculty of Dentistry, University of Chile and 13 controls. Salivary samples were collected, enzyme-linked immunosorbent assay was performed to quantify cortisol and kinetic reaction test was made to determine alpha-amylase activity. Perceived Stress Scale was applied at the beginning and at the end of the intervention.

Statistical Analysis Used:

Statistical analysis was applied using Stata v11.1 software. Shapiro–Wilk test was used to determine data distribution. The paired analysis was fulfilled by t-test or Wilcoxon signed-rank test. T-test or Mann–Whitney’s test was applied to compare longitudinal data. A statistical significance was considered when P< 0.05.

Results:

KY practice had an immediate effect on salivary cortisol. The activity of alpha-amylase did not show significant changes. A significant decrease of perceived stress in the study group was found.

Conclusions:

KY practice shows an immediate effect on salivary cortisol levels and on perceived stress after 3 months of practice.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433116/

Change Gene Expression to Lessen the Effects of Chronic Stress with Mind-Body Practices

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Change Gene Expression to Lessen the Effects of Chronic Stress with Mind-Body Practices

 

By John M. de Castro, Ph.D.

 

“Millions of people around the world already enjoy the health benefits of mind-body interventions like yoga or meditation, but what they perhaps don’t realise is that these benefits begin at a molecular level and can change the way our genetic code goes about its business. These activities are leaving what we call a molecular signature in our cells, which reverses the effect that stress or anxiety would have on the body by changing how our genes are expressed. Put simply, MBIs cause the brain to steer our DNA processes along a path which improves our wellbeing.” – Ivana Buric

 

There is an accumulating volume of research findings to demonstrate that Mind-body practices have highly beneficial effects on the health and well-being of humans. These include meditation, yoga, tai chi, qigong, biofeedback, progressive muscle relaxation, guided imagery, hypnosis, and deep breathing exercises. Because of their proven benefits the application of these practices to relieving human suffering has skyrocketed.

 

It is clear that Mind-body practices affect the physiology. In other words, the mind can alter the body. In turn, the genes can affect our minds. In fact, the genes have been shown to affect an individual’s inherent level of mindfulness. These interactions are well documented. The mechanisms by which they occur, however, are not well understood. It has been shown that contemplative practices help create balance in the inflammatory response which is very beneficial for health. But, the mechanism through which contemplative practices affect the immune system is not known. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. So, it would seem reasonable to investigate whether alterations in gene expressions might be the intermediary between mind-body therapies and health.

 

The immune system is designed to protect the body from threats like stress, infection, injury, and toxic chemicals. One of its tools is the Inflammatory response. Its primary effect is to increase blood circulation around the infected area, dilating the blood vessels around the site of inflammation. It also produces gaps in the cell walls surrounding the infected area, allowing the larger immune cells, to pass. It also tends to increase body temperature to further fight infection. This response works quite well for short-term infections and injuries and as such is an important defense mechanism for the body. But when inflammation is protracted and becomes chronic, it can itself become a threat to health, producing autoimmune diseases such as colitis, Chron’s disease, arthritis, heart disease, increased cancer risk, lung disease, sleep disruption, gum disease, decreased bone health, psoriasis, and depression.

Mind-body practices appear to relax the physical systems of the body including the immune system, reducing inflammation. Mind-body techniques such as yoga, Tai Chi and meditation have been shown to adaptively reduce the inflammatory response. Hence, it makes sense to investigate the effects of mind-body practices on gene expressions that underlie the immune and inflammatory responses. In today’s Research News article “What Is the Molecular Signature of Mind–Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472657/, Buric and colleagues review and summarize the published research literature on the effects of mind-body practices on gene expressions.

 

They found 18 published research articles. These articles, in general, report that following engaging in mind-body practices there is a reduction in the expression of genes that are involved in the inflammatory response resultant from chronic stress, particularly downregulation of NF-κB-targeted genes. It has been well established that mind-body practices reduce the psychological and physiological responses to stress. The published research on the effects of mind-body practices on gene expressions provide a mechanism by which these practices affect the stress response. They do so by affecting the physiology on the molecular level altering the genes that underlie the chemical processes involved in the inflammatory responses to stress.

 

These findings suggest that Mind-body practices can improve the health and well-being of the practitioner. One of the premiere mechanisms by which this is accomplished is by reducing the individual’s responses to the debilitating effects of chronic stress. Many of the difficulties produced by chronic stress are caused by producing a chronic inflammatory response damaging tissues. It appears that mind-body practices improve health by altering the genes that underlie these processes.

 

So, change gene expression to lessen the effects of chronic stress with mind-body practices.

 

“doing yoga or meditating may lead to a decrease in cyctokine production, and a reversal of the inflammatory gene, which ultimately lowers the risk of inflammation-related diseases and conditions.” – Brianna Steinhilber

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Buric, I., Farias, M., Jong, J., Mee, C., & Brazil, I. A. (2017). What Is the Molecular Signature of Mind–Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices. Frontiers in Immunology, 8, 670. http://doi.org/10.3389/fimmu.2017.00670

 

Abstract

There is considerable evidence for the effectiveness of mind–body interventions (MBIs) in improving mental and physical health, but the molecular mechanisms of these benefits remain poorly understood. One hypothesis is that MBIs reverse expression of genes involved in inflammatory reactions that are induced by stress. This systematic review was conducted to examine changes in gene expression that occur after MBIs and to explore how these molecular changes are related to health. We searched PubMed throughout September 2016 to look for studies that have used gene expression analysis in MBIs (i.e., mindfulness, yoga, Tai Chi, Qigong, relaxation response, and breath regulation). Due to the limited quantity of studies, we included both clinical and non-clinical samples with any type of research design. Eighteen relevant studies were retrieved and analyzed. Overall, the studies indicate that these practices are associated with a downregulation of nuclear factor kappa B pathway; this is the opposite of the effects of chronic stress on gene expression and suggests that MBI practices may lead to a reduced risk of inflammation-related diseases. However, it is unclear how the effects of MBIs compare to other healthy interventions such as exercise or nutrition due to the small number of available studies. More research is required to be able to understand the effects of MBIs at the molecular level.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472657/