Reduce Age-Associated Decline in Cerebrovascular Function with Tai Chi

Reduce Age-Associated Decline in Cerebrovascular Function with Tai Chi

 

By John M. de Castro, Ph.D.

 

“In addition to the physical components of tai chi, this form of exercise has mental and emotional advantages. Some studies have shown people who perform tai chi on a regular basis see improvements in cognitive function and memory.” – Phillips Lifeline

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. The elderly often have problems with attention, thinking, and memory abilities, known as mild cognitive impairment. An encouraging new development is that mindfulness practices such as meditation training and mindful movement practices can significantly reduce these declines in cognitive ability. In addition, it has been found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation,  yoga, and Tai Chi have been found to degenerate less with aging than non-practitioners.

 

Tai Chi has been practiced for thousands of years with benefits for health and longevityTai Chi training is designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Tai Chi practice has been found to be effective for an array of physical and psychological issues. Tai Chi has been shown to help the elderly improve attentionbalance, reducing fallsarthritiscognitive function, memory, and reduce age related deterioration of the brain. So, it makes sense to further study the effects of Tai Chi training on the brains of older adults.

 

In today’s Research News article “Tai Chi exercise improves age-associated decline in cerebrovascular function: a cross-sectional study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101197/ ) Li and colleagues recruited healthy older adult (aged 60-69 years) Tai Chi practitioners, age matched older adult non-practitioners, and healthy young adults (aged 21-25 years). They were measured for heart rate, blood pressure, and body mass index (BMI). They also underwent measurement of cerebrovascular hemodynamics.

 

They found that the older the participants the higher the systolic blood pressure but the lower the cerebrovascular blood flow. Importantly, the cerebrovascular hemodynamics of the older Tai Chi practitioners were significantly higher than the age matched controls and the levels approached those of the young adults. Including carotid blood flow velocity, overall elasticity of the arterial wall, and the degree of flow of small blood vessels and capillaries and reduced arterial resistance.

 

The present study was cross-sectional, comparing older adults who practiced Tai Chi to those who did not. This kind of design doesn’t allow for clear conclusions about causation. But previous research by others using training in Tai Chi demonstrated that it reduced age-related decline. So, it is likely that the benefits observed in the present study were also due to the practice of Tai Chi.

 

Age-related reductions in cerebrovascular hemodynamics are associated with cognitive decline and dementia but were not measured in the present study. But previous research has demonstrated that Tai Chi practice improves cognition and reduces dementia. So, it is likely that the observed better cerebrovascular hemodynamics in the older Tai Chi participants is a marker of improvements in cognition and reduced dementia. This suggests that age-related decline in cerebrovascular hemodynamics may be a major cause of cognitive decline and dementia with aging and that Tai Chi practice can reduce these declines by improving cerebrovascular hemodynamics.

 

So, reduce age-associated decline in cerebrovascular function with Tai Chi.

 

Tai Chi exercise had potential beneficial effects on cerebral hemodynamics, plasma risk factors, and balance ability in older community adults” – Guohua Zheng

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Li, L., Wang, J., Guo, S., Xing, Y., Ke, X., Chen, Y., He, Y., Wang, S., Wang, J., Cui, X., Wang, Z., & Tang, L. (2021). Tai Chi exercise improves age-associated decline in cerebrovascular function: a cross-sectional study. BMC geriatrics, 21(1), 293. https://doi.org/10.1186/s12877-021-02196-9

 

Abstract

Background

Tai Chi exercise has been reported to enhance physical and mental health in the older adults; however, the mechanism remains elusive.

Trial design

We recruited 289 older adults practicing Tai Chi for over 3 years, together with 277 age-matched older and 102 young adults as controls. 168 Tai Chi practitioners were successfully matched to 168 older controls aged 60–69 based on a propensity score for statistics.

Methods

Cerebrovascular function was evaluated by measuring the hemodynamics of the carotid artery. Spearman correlation was performed to validate the age-associated physiological parameters.

Results

Cerebrovascular function in older adults significantly degenerated compared with the young, and was substantially correlated with age. Compared with the older control group, Tai Chi practitioners showed significant improvements in CVHI (cerebral vascular hemodynamics indices) Score (P = 0.002), mean blood flow velocity (P = 0.014), maximal blood flow velocity (P = 0.04) and minimum blood flow velocity (P < 0.001), whereas the age-related increases in pulse wave velocity (P = 0.022), characteristic impedance (P = 0.021) and peripheral resistance (P = 0.044) were lowered.

Conclusions

These data demonstrate a rejuvenation role of Tai Chi in improving the age-related decline of the cerebrovascular function.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101197/

 

Reduce Blood Pressure in Patients with Hypertension with Tai Chi Practice

High blood pressure: Tai Chi proven to lower blood pressure readings |  Express.co.uk

Reduce Blood Pressure in Patients with Hypertension with Tai Chi Practice

 

By John M. de Castro, Ph.D.

 

“Tai chi may be just as effective as popular methods for lowering blood pressure, such as weight loss and lowered sodium intake. . . This means that enjoying tai chi regularly may lower your chance of heart disease.” – Abbott

 

High Blood Pressure (Hypertension) is an insidious disease because there are no overt symptoms. The individual feels fine. But it can be deadly as more than 360,000 American deaths, roughly 1,000 deaths each day, had high blood pressure as a primary or contributing cause. In addition, hypertension markedly increases the risk heart attack, stroke, heart failure, and kidney disease.  It is also a very common disorder with about 70 million American adults (29%) having high blood pressure and only about half (52%) of people with high blood pressure have their condition under control. Treatment frequently includes antihypertensive drugs. But these medications often have adverse side effects. So, patients feel lousy when taking the drugs, but fine when they’re not. So, compliance is a major issue with many patients not taking the drugs regularly or stopping entirely.

 

Obviously, there is a need for alternative to drug treatments for hypertension. Mindfulness practices have been shown to aid in controlling hypertension. Mindful movement practices such Tai Chi and Qigong are ancient Chinese practices involving mindfulness and gentle movements. They are easy to learn, safe, and gentle. So, it may be appropriate for patients with hypertension who lack the ability to engage in strenuous exercises. Indeed, Tai Chi practice has been shown to reduce blood pressure. The research has been accumulating. So, it makes sense to summarize what has been learned.

 

In today’s Research News article “Tai Chi as a Therapy of Traditional Chinese Medicine on Reducing Blood Pressure: A Systematic Review of Randomized Controlled Trials.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437614/ ) Pan and colleagues review, summarize, and perform a meta-analysis of the published randomized controlled research studies of the effects of Tai Chi practice on blood pressure in patients with hypertension. They identified 24 published randomized controlled trials including a total of 2095 participants.

 

They report that the published research found that Tai Chi practice produced significant reductions in both Systolic and Diastolic blood pressure and quality of life in the patients with hypertension. They also report that the improvement in blood pressure produced by Tai Chi practice was equivalent to that produced by antihypertensive drugs and aerobic exercise.

 

The published research, then demonstrates that Tai Chi practice is a safe and effective treatment to reduce blood pressure in patients with hypertension and it is as effective as antidepressant drugs. But, Tai Chi practice does not have the side effects of the drugs. It was also as effective as aerobic exercise. But, Tai Chi practice can be practiced in social groups making it fun, improving the likelihood of long-term engagement in the practice. So, Tai Chi practice should be recommended for lowering blood pressure in patients with hypertension.

 

So, reduce blood pressure in patients with hypertension with Tai Chi practice.

 

As many Americans grow older, they have become more concerned with staving off high blood pressure, which leads to strokes, heart attacks and kidney disease. These life-threatening diseases can be mitigated by the relaxed, slow movements of Tai Chi, a practice that prevents and even lowers blood pressure.” Tai Chi for Healthy Living

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Pan, X., Tian, L., Yang, F., Sun, J., Li, X., An, N., Xing, Y., Su, X., Liu, X., Liu, C., Gao, Y., & Xing, Y. (2021). Tai Chi as a Therapy of Traditional Chinese Medicine on Reducing Blood Pressure: A Systematic Review of Randomized Controlled Trials. Evidence-based complementary and alternative medicine : eCAM, 2021, 4094325. https://doi.org/10.1155/2021/4094325

 

Abstract

Objective

This study systematically evaluated the effects of Tai Chi exercise on blood pressure, body mass index (BMI), and quality of life (QOL) in patients with hypertension. A meta-analysis was performed to provide a reliable reference for clinical practice.

Methods

We searched for randomized controlled trials (RCTs) in five English databases and two Chinese databases, with the earliest data dated December 5, 2020. A quality assessment of the methods and a meta-analysis were also conducted.

Results

The meta-analysis of 24 studies showed that the intervention group showed better outcomes in terms of systolic blood pressure (SBP) (SMD −1.05, 95% CI −1.44 to −0.67, P ≤ 0.001; I2 = 93.7%), diastolic blood pressure (DBP) (SMD −0.91, 95% CI −1.24 to −0.58, P ≤ 0.001; I2 = 91.9%), and QOL (physical functioning (SMD 0.86, 95% CI 0.36 to 1.37, P=0.001; I2 = 91.3%), role-physical (SMD 0.86, 95% CI 0.61 to 1.11, P ≤ 0.001; I2 = 65%), general health (SMD 0.75, 95% CI 0.32 to 1.17, P=0.001; I2 = 88.1%), bodily pain (SMD 0.65, 95% CI 0.29 to 1.00, P ≤ 0.001; I2 = 83.1%), vitality (SMD 0.71, 95% CI 0.34 to 1.07, P ≤ 0.001; I2 = 84.3%), social functioning (SMD 0.63, 95% CI 0.07 to 1.19, P=0.027; I2 = 93.1%), role-emotional (SMD 0.64, 95% CI 0.22 to 1.06, P=0.003; I2 = 88.1%), and mental health (SMD 0.73, 95% CI 0.31 to 1.16, P=0.001; I2 = 88.2%)) compared to those of the control group. However, no significant improvements were seen in BMI of the intervention group (SMD −0.08, 95% CI −0.35 to −0.19, P=0.554; I2 = 69.4%) compared to that of the control group.

Conclusion

Tai Chi is an effective intervention to improve SBP and DBP in patients with essential hypertension.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437614/

 

Reduce Anxiety Around Cardiac Surgery with Yogic Breathing

Reduce Anxiety Around Cardiac Surgery with Yogic Breathing

 

By John M. de Castro, Ph.D.

 

“Anxiety is the physical, mental and emotional reaction to stress. Both can be calmed through the practice of yoga breathing, also called pranayama.” – M. Patino

 

Patients scheduled for major surgeries usually experience anxiety. This is thoroughly understandable, but this anxiety can contribute to cardiac mortality. Yoga training has been shown to improve health and well-being. It has also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. There are a wide variety of different yoga training techniques. But most contain breathing exercises. It is not known if these yogic breathing techniques can help relieve anxiety associated with major surgery.

 

In today’s Research News article “Effect of Short-Term Yoga-Based-Breathing on Peri-Operative Anxiety in Patients Undergoing Cardiac Surgery.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191222/ ) Azeez and colleagues recruited adult patients who were scheduled for cardiac surgery and randomly assigned them to either a no-treatment control condition or to receive 5 daily 60-minute sessions of yogic breathing including alternate nostril breathing, bee breathing, Udgith breathing, Sheetali breathing, and yoga nidra. They completed measures of anxiety before training, pre-surgery and post-surgery.

 

They found that in comparison to baseline and the control condition, the group that performed yogic breathing had significantly lower levels of both state and trait anxiety before surgery and another significant decrease after surgery. These findings need to be tempered with the understanding that the comparison, control, condition was passive leaving open the possibility of expectancy (placebo) effects, bias, and attentional effects. Future research should incorporate an active control condition, e.g. cardiac education.

 

Previous controlled research has demonstrated that yogic breathing reduces stress levels and improves psychological well-being. So, it I likely that the present results were due to yogic breathing exercises relieving anxiety. Although not measured, it would be expected that the lower anxiety levels in these cardiac surgery patients would lead to better surgical outcomes. It remains for future research to follow the patients after surgery to examine recovery and cardiac outcomes.

 

So, reduce anxiety around cardiac surgery with yogic breathing.

 

There are many ways to combat anxiety, but perhaps none as quickly – and naturally – effective as certain forms of Pranayama. Pranayama is conscious breathwork and is often used in yoga, mindfulness practices and meditation.” – YogiApproved

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Azeez, A. M., Puri, G. D., Samra, T., & Singh, M. (2021). Effect of Short-Term Yoga-Based-Breathing on Peri-Operative Anxiety in Patients Undergoing Cardiac Surgery. International journal of yoga, 14(2), 163–167. https://doi.org/10.4103/ijoy.IJOY_120_20

 

Abstract

Background:

Peri-operative anxiety in patients scheduled for cardiac surgery is detrimental. This study evaluated the effect of short-term yoga based-breathing with different variations on peri-operative anxiety.

Materials and Methods:

A prospective randomized controlled study was conducted in patients aged 20–60 years scheduled for major cardiac surgery. Patients in Yoga group were trained for yoga based-breathing with different variations for 5 days; no intervention was done in controls.

Results:

We analyzed twenty patients in each group. Anxiety scores measured at baseline, presurgery, and postsurgery were entered as the within-subjects factor; group status was entered as the between-subjects factor in the RMANOVA. Baseline demographics and anxiety scores were comparable. The short-term yoga-based breathing exercise-training program had a statistically significant effect on state (F = 13.45, P < 0.0001), Trait (F = 13.29, P < 0.0001) and total anxiety scores (F = 29.44, P < 0.0001) at different time points for yoga over control group.

Conclusion:

Short-term yoga-based breathing for 5 days lowers presurgery and postsurgery anxiety in patients undergoing cardiac surgery.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191222/

 

Alter the Genes for Better Health with Meditation

Alter the Genes for Better Health with Meditation

 

By John M. de Castro, Ph.D.

 

“meditation practices seem . . . promote endocrinal, neuronal, and behavioral functions. This suggests that the achievement of a state of inner silence through the practice of meditation can prevent or reverse the detrimental effects of a stressful environment.“ – Sabrina Venditti

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

 

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. Hence, it is important to study the epigenetic alterations in gene expressions produced by meditation practice to determine if these effects are the intermediary between meditation and health.

 

In today’s Research News article “Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/ ) Wenuganen and colleagues recruited older (> 60 years of age) healthy adult experienced practitioners of Transcendental Meditation and matched non-practitioners. Blood was drawn and analyzed for gene expression with microarrays and polymerase chain reaction.

 

They found that the genes of the Transcendental Meditation practitioners were in general significantly downregulated (lower expression) than the non-practitioners. “Sixty-two genes were related to hematologic diseases, 26 to coronary artery disease, 34 to diabetes complications, 49 to inflammation, and 64 to CVD. All these disease-related genes were downregulated in the TM group relative to the control group.” The genes found to have lower expression in the Transcendental Meditation practitioners were related to inflammatory responses and suppressed energy efficiency, while those upregulated (higher expression) were related to immune system function.

 

These epigenetic findings suggest that Transcendental Meditation practice over years of practice improve the immune system and energy efficiency while reducing inflammation in older individuals. These epigenetic changes suggest that Transcendental Meditation practice improves the physiology’s ability to maintain health by being better prepared to respond to disease and stress. This suggests a mechanism by which meditation practice improves health and longevity.

 

So, alter the genes for better health with meditation.

 

meditation, yoga, and Tai Chi . . . all seem to have a beneficial effect on the expression of a slew of different genes. And, as you might expect, the affected genes are generally those involved in stress and inflammation.” – Alice Walton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are a

Alter the Genes for Better Health with Meditation

 

By John M. de Castro, Ph.D.

 

“meditation practices seem . . . promote endocrinal, neuronal, and behavioral functions. This suggests that the achievement of a state of inner silence through the practice of meditation can prevent or reverse the detrimental effects of a stressful environment.“ – Sabrina Venditti

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

 

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. Hence, it is important to study the epigenetic alterations in gene expressions produced by meditation practice to determine if these effects are the intermediary between meditation and health.

 

In today’s Research News article “Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/ ) Wenuganen and colleagues recruited older (> 60 years of age) healthy adult experienced practitioners of Transcendental Meditation and matched non-practitioners. Blood was drawn and analyzed for gene expression with microarrays and polymerase chain reaction.

 

They found that the genes of the Transcendental Meditation practitioners were in general significantly downregulated (lower expression) than the non-practitioners. “Sixty-two genes were related to hematologic diseases, 26 to coronary artery disease, 34 to diabetes complications, 49 to inflammation, and 64 to CVD. All these disease-related genes were downregulated in the TM group relative to the control group.” The genes found to have lower expression in the Transcendental Meditation practitioners were related to inflammatory responses and suppressed energy efficiency, while those upregulated (higher expression) were related to immune system function.

 

These epigenetic findings suggest that Transcendental Meditation practice over years of practice improve the immune system and energy efficiency while reducing inflammation in older individuals. These epigenetic changes suggest that Transcendental Meditation practice improves the physiology’s ability to maintain health by being better prepared to respond to disease and stress. This suggests a mechanism by which meditation practice improves health and longevity.

 

So, alter the genes for better health with meditation.

 

meditation, yoga, and Tai Chi . . . all seem to have a beneficial effect on the expression of a slew of different genes. And, as you might expect, the affected genes are generally those involved in stress and inflammation.” – Alice Walton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available at the Contemplative Studies Blog http://contemplative-studies.org/wp/

They are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wenuganen, S., Walton, K. G., Katta, S., Dalgard, C. L., Sukumar, G., Starr, J., Travis, F. T., Wallace, R. K., Morehead, P., Lonsdorf, N. K., Srivastava, M., & Fagan, J. (2021). Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health. Medicina (Kaunas, Lithuania), 57(3), 218. https://doi.org/10.3390/medicina57030218

 

Abstract

Background and Objectives: Stress can overload adaptive mechanisms, leading to epigenetic effects harmful to health. Research on the reversal of these effects is in its infancy. Early results suggest some meditation techniques have health benefits that grow with repeated practice. This study focused on possible transcriptomic effects of 38 years of twice-daily Transcendental Meditation® (TM®) practice. Materials and Methods: First, using Illumina® BeadChip microarray technology, differences in global gene expression in peripheral blood mononuclear cells (PBMCs) were sought between healthy practitioners and tightly matched controls (n = 12, age 65). Second, these microarray results were verified on a subset of genes using quantitative polymerase chain reaction (qPCR) and were validated using qPCR in larger TM and control groups (n = 45, age 63). Bioinformatics investigation employed Ingenuity® Pathway Analysis (IPA®), DAVID, Genomatix, and R packages. Results: The 200 genes and loci found to meet strict criteria for differential expression in the microarray experiment showed contrasting patterns of expression that distinguished the two groups. Differential expression relating to immune function and energy efficiency were most apparent. In the TM group, relative to the control, all 49 genes associated with inflammation were downregulated, while genes associated with antiviral and antibody components of the defense response were upregulated. The largest expression differences were shown by six genes related to erythrocyte function that appeared to reflect a condition of lower energy efficiency in the control group. Results supporting these gene expression differences were obtained with qPCR-measured expression both in the well-matched microarray groups and in the larger, less well-matched groups. Conclusions: These findings are consistent with predictions based on results from earlier randomized trials of meditation and may provide evidence for stress-related molecular mechanisms underlying reductions in anxiety, post-traumatic stress disorder (PTSD), cardiovascular disease (CVD), and other chronic disorders and diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

 

re also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wenuganen, S., Walton, K. G., Katta, S., Dalgard, C. L., Sukumar, G., Starr, J., Travis, F. T., Wallace, R. K., Morehead, P., Lonsdorf, N. K., Srivastava, M., & Fagan, J. (2021). Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health. Medicina (Kaunas, Lithuania), 57(3), 218. https://doi.org/10.3390/medicina57030218

 

Abstract

Background and Objectives: Stress can overload adaptive mechanisms, leading to epigenetic effects harmful to health. Research on the reversal of these effects is in its infancy. Early results suggest some meditation techniques have health benefits that grow with repeated practice. This study focused on possible transcriptomic effects of 38 years of twice-daily Transcendental Meditation® (TM®) practice. Materials and Methods: First, using Illumina® BeadChip microarray technology, differences in global gene expression in peripheral blood mononuclear cells (PBMCs) were sought between healthy practitioners and tightly matched controls (n = 12, age 65). Second, these microarray results were verified on a subset of genes using quantitative polymerase chain reaction (qPCR) and were validated using qPCR in larger TM and control groups (n = 45, age 63). Bioinformatics investigation employed Ingenuity® Pathway Analysis (IPA®), DAVID, Genomatix, and R packages. Results: The 200 genes and loci found to meet strict criteria for differential expression in the microarray experiment showed contrasting patterns of expression that distinguished the two groups. Differential expression relating to immune function and energy efficiency were most apparent. In the TM group, relative to the control, all 49 genes associated with inflammation were downregulated, while genes associated with antiviral and antibody components of the defense response were upregulated. The largest expression differences were shown by six genes related to erythrocyte function that appeared to reflect a condition of lower energy efficiency in the control group. Results supporting these gene expression differences were obtained with qPCR-measured expression both in the well-matched microarray groups and in the larger, less well-matched groups. Conclusions: These findings are consistent with predictions based on results from earlier randomized trials of meditation and may provide evidence for stress-related molecular mechanisms underlying reductions in anxiety, post-traumatic stress disorder (PTSD), cardiovascular disease (CVD), and other chronic disorders and diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

 

Mindfulness-Based Therapies Effectively Treat Cardiovascular Disease

Mindfulness-Based Therapies Effectively Treat Cardiovascular Disease

 

By John M. de Castro, Ph.D.

 

What’s good for the mind also tends to be good for the heart. The mind-calming practice of meditation may play a role in reducing your risk of heart disease.” – Harvard Health

 

Cardiovascular disease is the number one killer. A myriad of treatments has been developed including a variety of surgical procedures and medications. In addition, lifestyle changes have proved to be effective including quitting smoking, weight reduction, improved diet, physical activity, and reducing stresses. Unfortunately, for a variety of reasons, 60% of cardiovascular disease patients decline engaging in these lifestyle changes, making these patients at high risk for another attack.

 

Contemplative practices have been shown to be safe and effective alternative treatments for cardiovascular disease. Practices such as meditation, tai chi, and yoga, have been shown to be helpful for heart health and to reduce the physiological and psychological responses to stress. They have also been shown to be effective in maintaining cardiovascular health and the treatment of cardiovascular disease. The research has been accumulating. So, it makes sense to pause and take a look at what has been learned.

 

In today’s Research News article “Mindfulness-Based Interventions for Physical and Psychological Wellbeing in Cardiovascular Diseases: A Systematic Review and Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227381/ ) Marino and colleagues review, summarize and perform a meta-analysis of the published research studies of the effectiveness of mindfulness-based therapies for the treatment of cardiovascular diseases. They identified 17 published research studies.

 

They report that the published research studies found that mindfulness-based therapies produced significant decreases in systolic blood pressure, heart palpitations, heart rate, depression, and perceived stress, and significant increases in the quality of life of patients with cardiovascular disease. Hence, mindfulness-based therapies are effective in improving the physiological and psychological state of patients with cardiovascular disease and should be recommended for the treatment of these patients.

 

So, mindfulness-based therapies effectively treat cardiovascular disease.

 

people who meditated had lower rates of high cholesterol, high blood pressure, diabetes, stroke, and coronary artery disease.” – Science Daily

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Marino, F., Failla, C., Carrozza, C., Ciminata, M., Chilà, P., Minutoli, R., Genovese, S., Puglisi, A., Arnao, A. A., Tartarisco, G., Corpina, F., Gangemi, S., Ruta, L., Cerasa, A., Vagni, D., & Pioggia, G. (2021). Mindfulness-Based Interventions for Physical and Psychological Wellbeing in Cardiovascular Diseases: A Systematic Review and Meta-Analysis. Brain sciences, 11(6), 727. https://doi.org/10.3390/brainsci11060727

 

Abstract

Background: Recently, there has been an increased interest in the efficacy of mindfulness-based interventions (MBI) for people with cardiovascular diseases (CVD), although the exact beneficial effects remain unclear. Methods: This review aims to establish the role of MBI in the management of wellbeing for patients with CVD. Seventeen articles have been included in this systematic synthesis of the literature and eleven in the meta-analysis. Results: Considering physical (i.e., heart rate, blood pressure) and psychological outcomes (i.e., depression, anxiety, stress, styles of coping), the vast majority of studies confirmed that MBI has a positive influence on coping with psychological risk factors, also improving physiological fitness. Random-effects meta-analysis models suggested a moderate-to-large effect size in reducing anxiety, depression, stress, and systolic blood pressure. Conclusions: Although a high heterogeneity was observed in the methodological approaches, scientific literature confirmed that MBI can now be translated into a first-line intervention tool for improving physical and psychological wellbeing in CVD patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227381/

 

Improve the Mental, Physical, and Emotional Well-Being of Older Adults During Covid-19 Pandemic with Tai Chi

Improve the Mental, Physical, and Emotional Well-Being of Older Adults During Covid-19 Pandemic with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Tai Chi Chuan has a potential effect on the prevention, treatment and rehabilitation of COVID-19. Its potential mechanisms include reducing anxiety, relieving depression and stress, enhancing pulmonary and cardiovascular function, enhancing immunity and improving quality of life.” – Chen Xianjian

 

The COVID-19 pandemic has challenged the mental and physical health of the population. It has created intense stress on everyone but particularly the elderly isolating at home. Mindfulness is known to decrease the psychological and physical responses to stress. So, mindfulness training may be helpful in coping with the mental and physical challenges resulting from the COVID-19 pandemic. Tai Chi and Qigong are both mindfulness practices and gentle exercises. They have been shown to be beneficial for the health and well-being of individuals of a variety of ages, but particularly the elderly. So, it would seem reasonable to examine the ability of Tai Chi practice to improve the well-being of older adults during the Covid-19 pandemic.

 

In today’s Research News article “Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054611/ ) Solianik and colleagues recruited healthy sedentary older adults (over 60 years of age) during the Covid-19 pandemic and randomly assigned them to 10 weeks of twice a week for 60 minute Tai Chi practice or to a no treatment control condition. They were measured before and after training for heart rate, perceived stress, anxiety, depression cognitive performance, and motor performance. In addition, blood was drawn and assayed for brain-derived neurotrophic factor.

 

They found that in comparison to baseline and the control group, the older adults who practiced Tai Chi had significantly higher levels of brain-derived neurotrophic factor, high frequency power in the heart rate, visuospatial performance, response inhibition, and shifting mental set, and significantly lower reaction times, heart rate, perceived stress, and depression.

 

The results must be interpreted with the understanding that the control condition was no treatment in a sedentary group of older adults. So, it cannot be determined if the effects were due to Tai Chi itself or exercise in general. Nevertheless, Tai Chi practice resulted in significant improvements in cardiovascular fitness, brain development, cognitive performance, and psychological health.

 

Tai Chi practice is not strenuous, involves slow gentle movements, and is safe, having no appreciable side effects, it is appropriate the elderly. It can also be practiced without professional supervision and in groups making it inexpensive to deliver and fun to engage in. This suggests that during stressful times Tai Chi should be recommended for older adults for their mental, physical, and emotional well-being.

 

So, improve the mental, physical, and emotional well-being of older adults during Covid-19 pandemic with Tai Chi.

 

Older people should exercise for the entire duration of self-isolation. One large systematic review of falls prevention exercises emphasised the importance of maintaining exercise over time – benefits from Tai Chi were found after 20 weeks.” –  Jamie Hartmann-Boyce

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Solianik, R., Mickevičienė, D., Žlibinaitė, L., & Čekanauskaitė, A. (2021). Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic. Experimental gerontology, 150, 111363. https://doi.org/10.1016/j.exger.2021.111363

 

Abstract

The aim of this study was to determine the effect of a 10-week tai chi intervention on psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic. Participants aged 60–78 years were randomized to either a control group (n = 15) or a tai chi group (n = 15) for a 10-week period. The tai chi group received two, 8-form tai chi classes of 60 min duration per week. Changes in psychoemotional state, cognition, and the learning of fast and accurate reaching movements were assessed. In addition, the potential roles of the autonomic nervous system and brain-derived neurotrophic factor (BDNF) were investigated. Tai chi practice decreased (P < 0.05) perceived stress, whereas no change in autonomic nervous system activity was observed. Improvements in mental switching correlated with decreased depressive symptoms and increased BDNF levels (P < 0.05), whereas improvements in inhibitory control tended to correlate with BDNF levels (P = 0.08). Improvements in visuospatial processing tended to correlate with decreased depressive symptoms (P = 0.07) while improved visuospatial processing correlated with improved motor planning during learning tasks (P < 0.05). This study suggests that tai chi is an effective intervention that can be delivered under pandemic conditions to improve mental and physical function in older adults.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054611/

 

Hot Yoga is Superior in Improving Cardiovascular Health

Hot Yoga is Superior in Improving Cardiovascular Health

 

By John M. de Castro, Ph.D.

 

“It might be hard, but hot yoga can help improve strength, flexibility and balance, while helping decrease your risk of conditions such as diabetes and heart disease.” – Lydia Stephens

 

Cardiovascular disease is the number one killer, claiming more lives than all forms of cancer combined. “Heart disease is the leading cause of death for both men and women. About 610,000 people die of heart disease in the United States every year–that’s 1 in every 4 deaths. Every year about 735,000 Americans have a heart attack.” (Centers for Disease Control). A myriad of treatments has been developed for heart disease including a variety of surgical procedures and medications. But the safest effective treatments are lifestyle changes. These include quitting smoking, weight reduction, improved diet, physical activity, and reducing stresses. Other safe and effective treatments are contemplative practices, such as meditation, tai chi, and yoga, have also been shown to be helpful for heart health. These practices have also been shown to be helpful for producing the kinds of lifestyle changes needed such as smoking cessationweight reduction, and stress reduction.

 

Yoga is a mindfulness practice and exercise that has been shown to improve physical well-being and cardiovascular health. Hot Yoga is somewhat unique yoga practice as it is practiced in a heated environment (105°F, 40.6°C, 40% humidity). The hot environment is thought to soften the muscles making them more pliable and loosen the joints making them more flexible allowing the practitioner to go deeper into poses. The sweating that occurs is thought to help remove toxins and impurities. It is not known if hot yoga is better in improving cardiovascular health than regular yoga.

 

In today’s Research News article “Cardiovascular, Cellular, and Neural Adaptations to Hot Yoga versus Normal-Temperature Yoga.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191229/ ) Bourbeau and colleagues recruited adults and randomly assigned them to either practice normal yoga or hot yoga for 75 minutes 3 times per week for 4 weeks. Both normal and hot yoga sessions followed an identical taped standardized yoga program. The participants were measured before and after training for body size, maximal aerobic capacity (VO2Max), heat tolerance, and perceived stress. In addition, blood was drawn and assayed for adrenocorticotropic hormone, brain-derived neurotrophic factor, and heat shock protein 70.

 

They found that in comparison to baseline the hot yoga group had significant increases in maximal aerobic capacity (VO2Max) and heat shock protein 70, while the normal yoga group did not. Both yoga groups had significant increases in brain-derived neurotrophic factor. Neither yoga practices significantly altered plasma adrenocorticotropic hormone, perceived stress, or heat tolerance.

 

These results suggest that practicing yoga in a hot environment increases its ability to improve cardiovascular fitness (VO2Max) and cellular heat tolerance (Heat shock protein 70). Yoga in either form increase brain development (Brain-derived neurotrophic factor). This suggests for adult patients at risk for or having cardiovascular problems who can also tolerate high temperatures that hot yoga may be an effective treatment to improve cardiovascular function. The results also show as has been shown in multiple previous studies that yoga practice improve the physical well-being of the participants.

 

So, hot yoga is superior in improving cardiovascular health.

 

hot yoga promises a number of compelling health benefits, alleging to cure everything from back pain to high blood pressure to anxiety.” – Anna Dickens

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Bourbeau, K. C., Moriarty, T. A., Bellovary, B. N., Bellissimo, G. F., Ducharme, J. B., Haeny, T. J., & Zuhl, M. N. (2021). Cardiovascular, Cellular, and Neural Adaptations to Hot Yoga versus Normal-Temperature Yoga. International Journal of Yoga, 14(2), 115–126. https://doi.org/10.4103/ijoy.IJOY_134_20

 

Abstract

Context:

Chronic heat exposure promotes cardiovascular and cellular adaptations, improving an organism’s ability to tolerate subsequent stressors. Heat exposure may also promote neural adaptations and alter the neural–hormonal stress response. Hot-temperature yoga (HY) combines mind–body exercise with heat exposure. The added heat component in HY may induce cardiovascular and cellular changes, along with neural benefits and modulation of stress hormones.

Aims:

The purpose of the present study is to compare the cardiovascular, cellular heat shock protein 70 (HSP70), neural, and hormonal adaptations of HY versus normal-temperature yoga (NY).

Settings and Design:

Twenty-two subjects (males = 11 and females = 11, 26 ± 6 years) completed 4 weeks of NY (n = 11) or HY (n = 11, 41°C, 40% humidity). Yoga sessions were performed 3 times/week following a modified Bikram protocol.

Subjects and Methods:

Pre- and posttesting included (1) hemodynamic measures during a heat tolerance test and maximal aerobic fitness test; (2) neural and hormonal adaptations using serum brain-derived neurotrophic factor (BDNF) and adrenocorticotropic hormone (ACTH), along with a mental stress questionnaire; and (3) cellular adaptations (HSP70) in peripheral blood mononuclear cells (PBMCs).

Statistical Analysis:

Within- and between-group Student’s t-test analyses were conducted to compare pre- and post-VO2 max, perceived stress, BDNF, HSP70, and ACTH in HY and NY groups.

Results:

Maximal aerobic fitness increased in the HY group only. No evidence of heat acclimation or change in mental stress was observed. Serum BDNF significantly increased in yoga groups combined. Analysis of HSP70 suggested higher expression of HSP70 in the HY group only.

Conclusions:

Twelve sessions of HY promoted cardiovascular fitness and cellular thermotolerance adaptations. Serum BDNF increased in response to yoga (NY + HY) and appeared to not be temperature dependent.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191229/

 

Improve Hypertension and Hyperlipidemia in Older Adults with Tai Chi

Improve Hypertension and Hyperlipidemia in Older Adults with Tai Chi

 

By John M. de Castro, Ph.D.

 

Tai Chi is not only a suitable exercise for elderly people with obesity, but it can also help to regulate BP, improve heart and lung function in these individuals, as well as reduce the incidence of cardiovascular disease and other chronic diseases, helping to improve their quality of life.” – Sun Lei

 

High Blood Pressure (Hypertension) is an insidious disease because there are no overt symptoms. The individual feels fine. But it can be deadly as more than 360,000 American deaths, roughly 1,000 deaths each day, had high blood pressure as a primary or contributing cause. In addition, hypertension markedly increases the risk heart attack, stroke, heart failure, and kidney disease.  It is also a very common disorder with about 70 million American adults (29%) having high blood pressure and only about half (52%) of people with high blood pressure have their condition under control. Treatment frequently includes antihypertensive drugs. But these medications often have adverse side effects. So, patients feel lousy when taking the drugs, but fine when they’re not. So, compliance is a major issue with many patients not taking the drugs regularly or stopping entirely.

 

Obviously, there is a need for alternative to drug treatments for hypertension. Mindfulness practices have been shown to aid in controlling hypertension. Mindful movement practices such Tai Chi and Qigong are ancient Chinese practices involving mindfulness and gentle movements. They are easy to learn, safe, and gentle. So, it may be appropriate for patients with hypertension who lack the ability to engage in strenuous exercises. Indeed, Tai Chi practice has been shown to reduce blood pressure.

 

In today’s Research News article “A Randomized Trial of Tai Chi on Preventing Hypertension and Hyperlipidemia in Middle-Aged and Elderly Patients.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160700/ ) Wen and colleagues recruited patients with hypertension and hyperlipidemia between the ages of 40-75 years. They were randomly assigned to practice for 6 weeks, 3 time per week, for 60 minutes either simplified Tai Chi (24 form Yang style) or a Wu Style Tai Chi (60 forms) that was designed for hypertension and hyperlipidemia. They also practiced at home for 30 minutes a day. They were measured before and after the interventions for body size, blood pressure, blood glucose, and blood lipids.

 

They found that the patients who practiced Wu Style Tai Chi in comparison to the simplified Tai Chi had significantly greater reductions in both systolic and diastolic blood pressure, triglycerides, and LDL Cholesterol and greater increases in HDL Cholesterol in comparison to baseline. In addition, a greater percentage of patients who practiced Wu Style Tai Chi discontinued antihypertensive drugs and showed clinically significant reductions in cardiovascular disease.

 

In the present study both forms of Tai Chi produced improvements in hypertension and hyperlipidemia as has been observed in previous research. But the present study demonstrated that Wu Style Tai Chi produces superior results. Wu Style is more complex and also emphasizes reverse abdominal breathing matched to the movements. It is believed that this increases circulation and may be responsible for the greater improvements. Regardless, Tai Chi is a safe and effective treatment for hypertension and hyperlipidemia in older adults.

 

So, improve hypertension and hyperlipidemia in older adults with Tai Chi.

 

tai chi is a promising and safe exercise alternative for patients with coronary heart disease who are unable or unwilling to attend traditional CR, in particular for older people, women, and deconditioned individuals.” – Elena Salmoirago‐Blotcher

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wen, J., & Su, M. (2021). A Randomized Trial of Tai Chi on Preventing Hypertension and Hyperlipidemia in Middle-Aged and Elderly Patients. International journal of environmental research and public health, 18(10), 5480. https://doi.org/10.3390/ijerph18105480

 

Abstract

In our randomized controlled trial, we investigated whether Wu-style Tai Chi (Tai Chi combined with Daoyin) as a potential exercise prescription is more effective than simplified Tai Chi in the prevention and treatment of hypertension and hyperlipidemia in the middle-aged and elderly. We randomly assigned 66 patients with hypertension and hyperlipidemia to one of the two groups: the Wu-style Tai Chi group or the simplified Tai Chi group; the simplified Tai Chi group only exercised simplified Tai Chi three times a week for 6 weeks. The Wu-style Tai Chi group participated in 60 min of Wu-style Tai Chi three times a week for 6 weeks. Serum biochemical tests were conducted at baseline and at the end of the study. Measurements of blood pressure were performed at the same time. Primary outcomes were compared within and between groups at baseline and at 6 weeks. The participants in the Wu-style Tai Chi group performed, at 6 weeks, significantly better than baseline on all of the primary outcomes (p value ≤ 0.05). The results also show significant difference within the simplified Tai Chi group from baseline to 6 weeks in TCHO (mmol/L), SBP (mmHg), and LDL-C (mmol/L) (p value < 0.05). From baseline to 6 weeks, the Wu-style Tai Chi group had significant differences at more test indexes in serum and blood pressure than the simplified Tai Chi group. At 6 weeks, the Wu-style Tai Chi group had a significantly greater mean improvement in the SBP (mmHg) than did the simplified Tai Chi group (mean between-group difference, −5.80 (mmHg) [95% CI, −14.01 to 2.41]; p = 0.007). The results showed that, compared with simplified Tai Chi, Wu-style Tai Chi had a better effect on hypertension in the middle-aged and elderly. At 6 weeks in LDL-C (mmol/L), the Wu-style Tai Chi group had significantly greater improvement between the two groups (means between-group difference, −0.45 (mmol/L) [95% CI, −0.89 to −0.17]; p = 0.03). The results showed that Wu-style Tai Chi protected the cardiovascular system of the middle-aged and elderly in improving LDL-C (mmol/L), and was more significant than simplified Tai Chi. After 6 weeks of exercise, Wu-style Tai Chi could effectively improve hyperlipidemia and hypertension. The total effective rate of cardiovascular disease was 90.00%. There was significant difference in the treatment effect of hypertension and hyperlipidemia between the two groups during 6 weeks (p = 0.039), showing that, in a small population of middle-aged and elderly subjects, Wu style Tai Chi could be useful in managing important CV risk factors, such as hypertension and hyperlipidemia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160700/

Mindfulness Improves Physical and Mental Well-Being

Mindfulness Improves Physical and Mental Well-Being

 

By John M. de Castro, Ph.D.

 

“scientists have found that practicing mindfulness is associated with changes in the structure and function of the brain as well as changes in our body’s response to stress, suggesting that this practice has important impacts on our physical and emotional health.” –  University of Minnesota

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mentalphysical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of mental and physical illnesses. It appears to be beneficial across ages, from children, to adolescents, to the elderly. And it appears to be beneficial across genders, personalitiesrace, and ethnicity. The breadth and depth of benefits is unprecedented. There is no other treatment or practice that has been shown to come anyway near the range of mindfulness’ positive benefits.

 

Research on mindfulness effects on mental and physical health has exploded over the last few decades. So, it makes sense to pause and examine what has been learned. In today’s Research News article “Mindfulness-based interventions: an overall review” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083197/ )  Zhang and colleagues reviewed and summarized the randomized controlled trials and meta-analyses of the effects of mindfulness-based practices on mental and physical health.

 

They report that the published research studies and meta-analyses found that mindfulness-based practices produced significant improvements in mental health including anxiety, depression, anger, prosocial behavior, loneliness, physiological and psychological indicators of stress, insomnia, eating disorders, addictions, psychoses, Post-Traumatic Stress Disorder (PTSD), attention-deficit hyperactivity disorder (ADHD), and autism. They also report that mindfulness-based practices produced significant improvements in physical health including pain, hypertension, cardiovascular disease, obesity, diabetes, cancer, asthma, chronic obstructive pulmonary disease (COPD), aggression, and violence.

 

In addition, mindfulness-based practices produced safe, cost-effective improvements in professional and healthcare settings, in schools, and in the workplace. Further they report that mindfulness-based practices produced significant changes in the structure and activity of the nervous system, improvements in immune functioning and physiological markers of stress.

 

The review of the published research has provided a compelling case for the utilization of mindfulness-based practices for a myriad of psychological and physical problems in humans of all ages with and without disease. The range and depth of effects are unprecedented making a strong case for the routine training in mindfulness for the improvement of their well-being.

 

So, mindfulness improves physical and mental well-being.

 

engaging in mindfulness meditation cultivates our ability to both focus and broaden our attention, which is a practical way to elicit psychological well-being.” – Jennifer Wolkin

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Zhang, D., Lee, E., Mak, E., Ho, C. Y., & Wong, S. (2021). Mindfulness-based interventions: an overall review. British medical bulletin, ldab005. Advance online publication. https://doi.org/10.1093/bmb/ldab005

 

Abstract

Introduction

This is an overall review on mindfulness-based interventions (MBIs).

Sources of data

We identified studies in PubMed, EMBASE, CINAHL, PsycINFO, AMED, Web of Science and Google Scholar using keywords including ‘mindfulness’, ‘meditation’, and ‘review’, ‘meta-analysis’ or their variations.

Areas of agreement

MBIs are effective for improving many biopsychosocial conditions, including depression, anxiety, stress, insomnia, addiction, psychosis, pain, hypertension, weight control, cancer-related symptoms and prosocial behaviours. It is found to be beneficial in the healthcare settings, in schools and workplace but further research is warranted to look into its efficacy on different problems. MBIs are relatively safe, but ethical aspects should be considered. Mechanisms are suggested in both empirical and neurophysiological findings. Cost-effectiveness is found in treating some health conditions.

Areas of controversy

Inconclusive or only preliminary evidence on the effects of MBIs on PTSD, ADHD, ASD, eating disorders, loneliness and physical symptoms of cardiovascular diseases, diabetes, and respiratory conditions. Furthermore, some beneficial effects are not confirmed in subgroup populations. Cost-effectiveness is yet to confirm for many health conditions and populations.

Growing points

Many mindfulness systematic reviews and meta-analyses indicate low quality of included studies, hence high-quality studies with adequate sample size and longer follow-up period are needed.

Areas timely for developing research

More research is needed on online mindfulness trainings and interventions to improve biopsychosocial health during the COVID-19 pandemic; Deeper understanding of the mechanisms of MBIs integrating both empirical and neurophysiological findings; Long-term compliance and effects of MBIs; and development of mindfulness plus (mindfulness+) or personalized mindfulness programs to elevate the effectiveness for different purposes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083197/

Improve Hypertension with Yoga

Improve Hypertension with Yoga

 

By John M. de Castro, Ph.D.

 

“Yoga can reduce stress-induced hypertension, while addressing its underlying causes. It pacifies the sympathetic nervous system and slows down the heart, while teaching the muscles and mind to relax deeply.” – Marla Apt

 

High Blood Pressure (Hypertension) is an insidious disease because there are no overt symptoms. The individual feels fine. But it can be deadly as more than 360,000 American deaths, roughly 1,000 deaths each day, had high blood pressure as a primary or contributing cause. In addition, hypertension markedly increases the risk heart attack, stroke, heart failure, and kidney disease.  It is also a very common disorder with about 70 million American adults (29%) having high blood pressure and only about half (52%) of people with high blood pressure have their condition under control. Treatment frequently includes antihypertensive drugs. But these medications often have adverse side effects. So, patients feel lousy when taking the drugs, but fine when they’re not. So, compliance is a major issue with many patients not taking the drugs regularly or stopping entirely.

 

Obviously, there is a need for alternative to drug treatments for hypertension. Mindfulness practices have been shown to aid in controlling hypertension. Exercise is also known to help. So, yoga practice, which combines mindfulness practice with exercise would seem to be a good candidate practice for the treatment of hypertension. Indeed, yoga practice appears to lower blood pressure in hypertension.

 

In today’s Research News article “Effects of a health worker-led 3-month yoga intervention on blood pressure of hypertensive patients: a randomised controlled multicentre trial in the primary care setting.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981931/ ) Dhungana and colleagues recruited adults with hypertension who didn’t practice yoga and randomly assigned them to a wait-list control condition or to receive 5 2-hour yoga training sessions and 1 health education session followed by 90 days of home practice for 30 minutes per day for 5 days per week. They were measured before and after training for systolic and diastolic blood pressure, heart rate, and body size.

 

They found that in comparison to baseline and the wait-list control group, the patients with hypertension who practiced yoga had significant reductions in both systolic (8%) and diastolic (7%) blood pressure. These results are similar to those found in other studies that yoga practice lowers blood pressure in patients with hypertension. The contribution of the present study is to demonstrate that after training, yoga practice at home is a safe and effective treatment for hypertension.

 

So, Improve Hypertension with Yoga.

 

Adults who practice yoga with breathing and relaxation exercises at least three times a week may have lower blood pressure than people who don’t.” – Lisa Rapaport

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Dhungana, R. R., Pedisic, Z., Joshi, S., Khanal, M. K., Kalauni, O. P., Shakya, A., Bhurtel, V., Panthi, S., Ramesh Kumar, K. C., Ghimire, B., Pandey, A. R., Bista, B., Khatiwoda, S. R., McLachlan, C. S., Neupane, D., & de Courten, M. (2021). Effects of a health worker-led 3-month yoga intervention on blood pressure of hypertensive patients: a randomised controlled multicentre trial in the primary care setting. BMC public health, 21(1), 550. https://doi.org/10.1186/s12889-021-10528-y

 

Abstract

Background

Hypertension control remains a major challenge globally. A recent systematic review suggested that yoga has beneficial effects on reducing blood pressure. However, the role of yoga in hypertension management in primary health care has received little attention, and no studies have evaluated the impact of a yoga program fully delivered by health care staff on hypertension. This study, therefore, assessed the effects of a health worker-led yoga intervention on blood pressure reduction among hypertensives patients in the primary care setting.

Methods

This was a multicentric, two-arm, randomised trial conducted among hypertensive patients in seven Ayurveda Health Centres in Nepal between March 2017 and June 2018. One hundred and twenty-one participants who were on or without medications were randomised to intervention (n = 61) and wait-list control (n = 60) groups using stratified block randomisation. Participants in the intervention arm received an intervention consisting of an initial five-day structured yoga training at the centres and then a further home-based practice of yoga for five days a week for the following 90 days. Both intervention and control groups also participated in a 2-h health education session. The primary outcome of this trial was systolic blood pressure at 90-day follow-up. Data were analysed on an intention-to-treat basis using linear mixed-effects regression models.

Results

We included all 121 study participants (intervention/control = 61/60) in the primary analysis (52.1% males; mean ± SD age = 47.8 ± 10.8 years). The difference in systolic blood pressure between the intervention group and the control group was − 7.66 mmHg (95% CI: − 10.4, − 4.93). For diastolic blood pressure, the difference was − 3.86 mmHg (95% CI: − 6.65, − 1.06). No adverse events were reported by the participants.

Conclusions

A yoga program for hypertensive patients consisting of a five-day training in health centres and 90 days of practice at home is effective for reducing blood pressure. Significant benefits for hypertensive patients could be expected if such programmes would become a part of the standard treatment practice.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981931/