Improve Glycemic Control in Patients with Type 2 Diabetes with Tai Chi

September 15, 2022 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“Tai chi does not mean oriental wisdom or something exotic. It is the wisdom of your own senses, your own mind and body together as one process.” – Chungliang Al Huang

Diabetes is a major health issue. It is estimated that 30 million people in the United States have diabetes and the numbers are growing. Type 2 Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is the 7th leading cause of death in the United States. In addition, diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

Type 2 diabetes is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary lifestyle. Current treatments for Type 2 Diabetes focus on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. Tai Chi is mindfulness practice and a gentle exercise that has been found to improve the symptoms of Type 2 Diabetes. The research is accumulating. So, it is reasonable to examine what has been learned

In today’s Research News article “Effect of tai chi on glycaemic control, lipid metabolism and body composition in adults with type 2 diabetes: A meta-analysis and systematic review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814847/ ) Guo and colleagues review, summarize, and perform a meta-analysis of the published research studies of the effectiveness of Tai Chi practice in the treatment of Type 2 Diabetes. They identified 23 published randomized clinical trials.

They report that the published research found that in comparison to usual clinical care, patients who were given Tai Chi practice had significantly lower levels of body mass index, systolic and diastolic blood pressure, insulin levels, fasting blood glucose, blood glucose levels after meals, HbA1c, total cholesterol, and low density lipoproteins (LDL), and higher levels of high density lipoproteins (HDL). Tai Chi produced similar results in comparison to aerobic exercise with body mass index, fasting blood glucose levels, total cholesterol, triglycerides, and low-density lipoproteins (LDL). Tai Chi produced superior results to aerobic exercise in reducing HbA1c and increasing high density lipoproteins (HDL).

Hence, the research published to date indicates that Tai Chi practice is superior to usual clinical care in improving obesity, glycemic control, and plasma fats and is superior to aerobic exercise in improving glycemic control and blood fats. This suggests that Tai Chi practice should be recommended for patients with Type 2 Diabetes.

“Tai Chi Chuan, the great ultimate, strengthens the weak, raises the sick, invigorates the debilitated, and encourages the timid.” – Cheng Man-ch’ing

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

Study Summary

Guo S, Xu Y, Qin J, Chen Y, You Y, Tao J, Liu Z, Huang J. Effect of tai chi on glycaemic control, lipid metabolism and body composition in adults with type 2 diabetes: A meta-analysis and systematic review. J Rehabil Med. 2021 Mar 22;53(3):jrm00165. doi: 10.2340/16501977-2799. PMID: 33594445; PMCID: PMC8814847.

Abstract

Objective

The aim of this systematic review was to evaluate the effects of tai chi on metabolic control and body composition indicators in patients with type 2 diabetes mellitus.

Design

Systematic review and meta-analysis of existing literature.

Methods

Electronic resource databases were searched to collect eligible studies. Two reviewers selected studies and independently evaluated methodological quality.

Results

Twenty-three studies were included in this meta-analysis. The pooled results showed that tai chi had significant effects in improving metabolic indices, such as fasting blood glucose (mean difference (MD) = –1.04; 95% confidence interval (95% CI) –1.42 to 0.66; p < 0.01) and total cholesterol (MD = –0.50; 95% CI –0.86 to –0.13; p < 0.01) compared with conventional clinical therapy. Most indices did not support the use of tai chi over aerobic exercise, except for glycated haemoglobin (HbA1c) (MD = –0.24; 95% CI –0.49 to 0.00; p < 0.01) and high-density lipoprotein (MD = 0.07; 95% CI 0.01 to 0.12; p < 0.01).

Conclusion

Tai chi had better effects on metabolic control and body composition indicators than clinical conventional therapy, but only on HbA1c and HDL were superior than that of aerobic exercise. The best time-window for tai chi intervention may differ with different metabolic indices.

LAY ABSTRACT

Exercise therapy is a possible alternative and effective strategy for blood glucose control in patients with type 2 diabetes, since drug therapy is associated with side-effects, long-term loss of efficacy, and poor adherence to lifelong treatment. A review of evidence was performed regarding the effects of tai chi on glycaemic control and other indicators in patients with type 2 diabetes mellitus. The results indicate that tai chi not only improves metabolic control, e.g. fasting blood glucose and total cholesterol, but also improves body composition indicators, e.g. body mass index. However, benefits of tai chi over aerobic exercise were seen in only a few outcome measures. The type and methodology of studies varied widely, with discrepancies in intensity, frequency, and duration of tai chi; therefore, further high-quality research is needed in order to draw specific and accurate conclusions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814847/

Improve the Symptoms of Type 2 Diabetes with Yoga Therapy

May 25, 2022 psyjdc Leave a comment

Iyengar Yoga Exercises For Diabetes Mellitus Type 2 - YouTube

Improve the Symptoms of Type 2 Diabetes with Yoga Therapy

By John M. de Castro, Ph.D.

“Yoga can do more than just relax your body in mind — especially if you’re living with diabetes. Certain poses may help lower blood pressure and blood sugar levels while also improving circulation, leading many experts to recommend yoga for diabetes management.” – Emily Cronkleton

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes, and the numbers are growing. Type-2 Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

Type 2 diabetes is a common and increasingly prevalent illness that is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary lifestyle. Unlike Type I Diabetes, Type II does not require insulin injections. Instead, the treatment and prevention of Type 2 Diabetes focuses on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. A mindfulness practice that combines mindfulness with exercise is yoga and it has been shown to be helpful in the treatment of Type II Diabetes.

In today’s Research News article “Impact of an Integrated Yoga Therapy Protocol on Insulin Resistance and Glycemic Control in Patients with Type 2 Diabetes Mellitus.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798588/ ) Gowri and colleagues recruited adult patients with Type 2 diabetes and randomly assigned them to either receive twice weekly for 120 days sessions of yoga therapy or treatment as usual. Both groups received dietary advice. They were measured before treatment and 120 days later for body size and levels of insulin and lipids in the blood.

They found in comparison to baseline and the control group that the yoga therapy group had significantly lower body mass index (BMI), post-prandial and fasting blood glucose, HbA1c, insulin, insulin resistance, LDL cholesterol, and very-low density lipoproteins and higher levels of HDL cholesterol.

These are encouraging results that yoga therapy is a safe and effective treatment to improve the symptoms of type 2 diabetes. Future research should compare yoga therapy to other forms of exercise.

“Yoga therapy works predominantly by its ability to decrease the stress response, which in turn controls blood glucose levels. In addition, postures and other yogic techniques may benefit the function of abdominal organs like the pancreas via mechanical and energetic effects.” – Robyn Tiger

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

Study Summary

Mangala Gowri, M., Rajendran, J., Srinivasan, A. R., Bhavanani, A. B., & Meena, R. (2022). Impact of an Integrated Yoga Therapy Protocol on Insulin Resistance and Glycemic Control in Patients with Type 2 Diabetes Mellitus. Rambam Maimonides medical journal, 13(1), e0005. https://doi.org/10.5041/RMMJ.10462

Abstract

Objective

Diabetes mellitus (DM), characterized by chronic hyperglycemia, is attributed to relative insulin deficiency or resistance, or both. Studies have shown that yoga can modulate parameters of insulin resistance. The present study explored the possible beneficial effects of integrated yoga therapy with reference to glycemic control and insulin resistance (IR) in individuals with diabetes maintained on standard oral medical care with yoga therapy, compared to those on standard oral medical care alone.

Methods

In this study, the subjects on yoga intervention comprised 35 type 2 diabetics, and an equal number of volunteers constituted the control group. Subjects ranged in age from 30 to 70 years, with hemoglobin A1c (HbA1c) test more than 7%, and were maintained on diabetic diet and oral hypoglycemic agents. Blood samples were drawn prior to and after 120 days of integrated yoga therapy intervention. Fasting blood glucose (FBG), post-prandial blood glucose (PPBG), HbA1c, insulin, and lipid profile were assessed in both the intervention and control groups.

Results

The intervention group revealed significant improvements in body mass index (BMI) (0.7 kg/m2 median decrease; P=0.001), FBG (20 mg/dL median decrease; P<0.001), PPBG (33 mg/dL median decrease; P<0.001), HbA1c (0.4% median decrease; P<0.001), homeostatic model assessment for insulin resistance (HOMA-IR) (1.2 median decrease; P<0.001), cholesterol (13 mg/dL median decrease, P=0.006), triacylglycerol (22 mg/dL median decrease; P=0.027), low-density lipoprotein (6 mg/dL median decrease; P=0.004), and very-low-density lipoprotein levels (4 mg/dL median decrease; P=0.032). Increases in high-density lipoprotein after 120 days were not significant (6 mg/dL median increase; P=0.15). However, when compared to changes observed in patients in the control group, all these improvements proved to be significant.

Conclusion

Administration of integrated yoga therapy to individuals with diabetes leads to a significant improvement in glycemic control, insulin resistance, and key biochemical parameters.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798588/

Reduce Body Mass and Improve Body Composition in the Overweight Young Women with Yoga

December 26, 2021 psyjdc Leave a comment

Reduce Body Mass and Improve Body Composition in the Overweight Young Women with Yoga

By John M. de Castro, Ph.D.

“The purpose of exercise interventions should be to help youth with obesity find alternatives that increase their engagement with activity, and thus lead to more sustainable changes in lifestyle. Yoga practice is an excellent example of how to use more nontraditional approaches to engage students with exercise.” – Sarah Shultz

Obesity has become an epidemic in the industrialized world. In the U.S. the incidence of obesity, defined as a Body Mass Index (BMI) of 30 or above has more than doubled over the last 35 years to currently around 35% of the population, while two thirds of the population are considered overweight or obese (BMI > 25). Sadly, children and adolescents have not been spared with 1 in 5 school age children and young people (6 to 19 years) classified as obese.

Obviously, there is a need for effective treatments to prevent or treat obesity. But, despite copious research and a myriad of dietary and exercise programs, there still is no safe and effective treatment. Mindfulness is known to be associated with lower risk for obesity, alter eating behavior and improve health in obesity. This suggests that mindfulness training may be an effective treatment for overeating and overweight alone or in combination with other therapies. Yoga practice has been shown to have a myriad of physical and psychological benefits. These include significant loss in weight and body mass index (BMI), resting metabolism, and body fat and improve health in the obese.

In today’s Research News article “Effects of Continuous Yoga on Body Composition in Obese Adolescents.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410386/ ) Nongkhai and colleagues recruited overweight (BMI 23-29.5) young women (age 19-22 years) and randomly assigned them to either engage in continuous yoga practice 3 times per week for 50 minutes for 12 weeks or to a no treatment control condition. The yoga practice was designed to increase and maintain aerobic exercise levels (65% – 75% of maximum heart rate). Before, at the midpoint, and after training they were measured for body size and composition.

They found that in comparison to baseline and the control group the yoga group had significant decreases in their Body Mass Index (BMI) and body fat mass. While the control group had a significant decrease in muscle mass, the yoga group maintained their muscle mass. Hence, participation in yoga had positive body size and composition benefits for overweight young women.

In the present study, the intervention was a yoga practice that elevated and maintained aerobic levels. This makes it impossible to discern if the benefits were due to yoga per se or to the exercise. Nevertheless, these results to some extent replicate previous findings that yoga practice improves weight and body composition. Future research should contain a non-yoga aerobic exercise group. Regardless, it is clear that engaging in continuous yoga is improves the body size and composition of young women.

So, reduce body mass and improve body composition in the overweight young women with yoga.

“Yoga practice works to expand consciousness of overall health and well being. . . . many children and teens dealing with obesity who find a safe place in yoga to cultivate a positive sense of self that contributes to confidence.” – Abby Wills

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Na Nongkhai, M. P., Yamprasert, R., & Punsawad, C. (2021). Effects of Continuous Yoga on Body Composition in Obese Adolescents. Evidence-based complementary and alternative medicine : eCAM, 2021, 6702767. https://doi.org/10.1155/2021/6702767

Abstract

Overweight/obesity is a pressing international health concern, and conventional treatments demonstrate poor long-term efficacy. Several studies have shown that yoga can control risk factors for cardiovascular disease, obesity, and psychosocial stress. The present study aimed to assess the effect of continuous yoga (asanas, pranayama, and Surya Namaskar yoga) on body composition in overweight participants. Forty adolescents with obesity were enrolled in this study. The study was conceived as a prospective, single-center, single-blinded randomized controlled trial. The participants were divided into 2 groups: the intervention group (n = 20), which undertook a continuous yoga practice, and the control group (n = 20). Body composition, including body weight (BW), body mass index (BMI), body fat mass (BFM), and muscle mass, was evaluated using tetrapolar bioelectrical impedance (BIA). Our results showed that the mean BMI and BFM of the yoga intervention group were significantly decreased at week 8 and week 12. The muscle mass of the yoga group continued to improve at a rate of 0.515 per week, which was statistically significant. In conclusion, a continuous yoga practice had a tendency to decrease BMI and BFM and increase muscle mass. These findings demonstrate intervention effectiveness similar to that observed in other clinical research and indicate that continuous yoga practice may be used as an alternative therapy for obesity prevention and health promotion in adolescents with obesity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410386/

Improve Lipid Metabolism in Diabetes with Yoga

October 27, 2021 psyjdc Leave a comment

Improve Lipid Metabolism in Diabetes with Yoga

By John M. de Castro, Ph.D.

“Yoga, being a lifestyle incorporating exercise and stress management training, targets the elevated lipid levels in patients with diabetes.” – Nisha Shantakumari

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes and the numbers are growing. Type II Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

In today’s Research News article “Effectiveness of Yoga Lifestyle on Lipid Metabolism in a Vulnerable Population-A Community Based Multicenter Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303653/ ) Nagarathna and colleagues recruited a large nationwide rural and urban based sample of adults with no diabetes, prediabetes (high risk for development of Type 2 diabetes), or type 2 diabetes and randomly assigned them to receive either standard lifestyle treatment with lectures on diet, exercise, sleep and stress management or the same lifestyle treatment plus 3 months of daily, 60 minute, yoga practice consisting of postures, breathing practices, relaxation, pranayama, meditation. Blood was drawn before and after treatment and assayed for lipids.

They found that in comparison to baseline and the control group, the yoga group after training had significantly lower levels of blood total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein. This was true particularly for participants with high baseline blood lipid levels. These improvements were present for both males and females, for urban and rural participants, and for younger (<40 years of age) and older (>40) praticipants.

This study examined a very large nationwide community sample (>10,000) participants and is thus highly generalizable. It replicates previous research demonstrating the ability of yoga practice reduce blood fat levels and to improves patients with diabetes. But yoga is both a contemplative practice and an exercise. The control condition in this study did not contain exercise. So, it is impossible to tell if the improvements occurred due to yoga practice or to the exercise provided in the practice. Future studies should contain an alternative exercise control condition.

Regardless, it is clear that yoga practice improves blood lipid profiles in prediabetic and diabetic adults. This should help to restrain or delay the secondary health problems that are associated with diabetes. This should improve the quality of life, health, and well-being of the individuals.

So, improve lipid metabolism in diabetes with yoga.

“Yoga can do more than just relax your body in mind — especially if you’re living with diabetes. Certain poses may help lower blood pressure and blood sugar levels while also improving circulation, leading many experts to recommend yoga for diabetes management.” – Emily Cronkleton

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Nagarathna, R., Kumar, S., Anand, A., Acharya, I. N., Singh, A. K., Patil, S. S., Latha, R. H., Datey, P., & Nagendra, H. R. (2021). Effectiveness of Yoga Lifestyle on Lipid Metabolism in a Vulnerable Population-A Community Based Multicenter Randomized Controlled Trial. Medicines (Basel, Switzerland), 8(7), 37. https://doi.org/10.3390/medicines8070037

Abstract

Background: Dyslipidemia poses a high risk for cardiovascular disease and stroke in Type 2 diabetes (T2DM). There are no studies on the impact of a validated integrated yoga lifestyle protocol on lipid profiles in a high-risk diabetes population. Methods: Here, we report the results of lipid profile values of 11,254 (yoga 5932 and control 5322) adults (20–70 years) of both genders with high risk (≥60 on Indian diabetes risk score) for diabetes from a nationwide rural and urban community-based two group (yoga and conventional management) cluster randomized controlled trial. The yoga group practiced a validated integrated yoga lifestyle protocol (DYP) in nine day camps followed by daily one-hour practice. Biochemical profiling included glycated hemoglobin and lipid profiles before and after three months. Results: There was a significant difference between groups (p < 0.001 ANCOVA) with improved serum total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein in the yoga group compared to the control group. Further, the regulatory effect of yoga was noted with a significant decrease or increase in those with high or low values of lipids, respectively, with marginal or no change in those within the normal range. Conclusion: Yoga lifestyle improves and regulates (lowered if high, increased if low) the blood lipid levels in both genders of prediabetic and diabetic individuals in both rural and urban Indian communities.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303653/

Improve Diabetes in Older and Elderly Patients with Tai Chi

October 17, 2021 psyjdc Leave a comment

Improve Diabetes in Older and Elderly Patients with Tai Chi

By John M. de Castro, Ph.D.

“Tai Chi exercises can improve blood glucose levels and improve the control of type 2 diabetes and immune system response.” – Medical News Today

In today’s Research News article “A Meta-Analysis of the Effects of Tai Chi on Glucose and Lipid Metabolism in Middle-Aged and Elderly Diabetic Patients: Evidence from Randomized Controlled Trials.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007338/ ) Liu and colleagues review, summarize, and perform a meta-analysis of the published randomized controlled studies of the effectiveness of Tai Chi practice in the treatment of Type 2 Diabetes in older and elderly patients. They identified 14 published studies.

They report that the published studies found that Tai Chi practice produced significant reductions in fasting blood glucose levels, glycated hemoglobin, cholesterol, triglycerides, and low density lipoproteins, and significantly increased the levels of high density lipoproteins. They report that these improvements occurred predominantly in studies where Tai Chi was practiced for at least 50 minutes per day, for at least 12 weeks.

The findings of this meta-analysis suggests that Tai Chi practice is a safe and effective treatment for older and elderly patients with Type 2 Diabetes improving blood glucose and lipid profiles. It is important to note that Tai Chi practice is gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. Hence, Tai Chi practice is an almost ideal treatment for Type 2 Diabetes

So, improve diabetes in older and elderly patients with Tai Chi.

”Stress stands in the way of controlling diabetes. Since tai chi encourages mental relaxation and reduces stress, it follows that Tai Chi can improve the control of diabetes.” – Paul Lam

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Liu, Y. N., Wang, L., Fan, X., Liu, S., Wu, Q., & Qian, Y. L. (2021). A Meta-Analysis of the Effects of Tai Chi on Glucose and Lipid Metabolism in Middle-Aged and Elderly Diabetic Patients: Evidence from Randomized Controlled Trials. Evidence-based complementary and alternative medicine : eCAM, 2021, 6699935. https://doi.org/10.1155/2021/6699935

Abstract

This research review aimed to evaluate the effect of practicing Tai Chi on glucose and lipid metabolism in middle-aged and elderly diabetic patients. Furthermore, it aimed to provide a theoretical basis for the practice of Tai Chi as a way to improve glucose and lipid metabolism in middle-aged and elderly diabetic patients. Therefore, we searched for randomized controlled trials on the practice of Tai Chi in middle-aged and elderly diabetic patients in Chinese- and English-language electronic databases, such as Web of Science, PubMed, the Cochrane Library, EMBASE, Google Scholar, CNKI, Wanfang Database, and Weipu. We collected articles published no later than August 1, 2020. The methodological quality of the included studies was evaluated according to the standards of the Cochrane Collaboration System Evaluation Manual (version 5.1.0). Finally, 14 articles were included, showing an average Physiotherapy Evidence Database scale score of 6.57. The articles were meta-analyzed using Stata 14.0 software, showing that practicing Tai Chi improved middle-aged and elderly diabetic patients’ fasting blood glucose (WMD = −0.60, 95% CI [−1.08, −0.12], p=0.015), glycosylated hemoglobin (WMD = −0.87, 95% CI [−1.60, −0.14], p=0.019), total cholesterol (WMD = −0.48, 95% CI [−0.83, −0.14], p=0.006), triglycerides (WMD = −0.21, 95% CI [−0.37, −0.04], p=0.014), and low-density lipoprotein cholesterol level significantly (WMD = −0.32, 95% CI [−0.63,−0.00], p=0.050). Conversely, patients’ high-density lipoprotein cholesterol levels (WMD = 0.09, 95% CI [−0.01, 0.17], p=0.136) showed no obvious improvement. In conclusion, practicing Tai Chi in sessions lasting longer than 50 minutes (at least three times per week, for at least 12 weeks) can effectively improve glucose and lipid metabolism in middle-aged and elderly diabetic patients. However, several other factors affect glucose and lipid metabolism; therefore, further high-quality research is needed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007338/

Improve Physical and Mental Health with an Isha Yoga Retreat

August 18, 2021 psyjdc Leave a comment

Improve Physical and Mental Health with an Isha Yoga Retreat

By John M. de Castro, Ph.D.

“As we have physical science to create external wellbeing there is a whole inner dimension of science to create inner wellbeing. I call it Inner Engineering.” – Sadhguru

Retreat can be a powerful experience. But it can be quite difficult and challenging. It can be very tiring and physically challenging as engaging in sitting meditation repeatedly over the day is guaranteed to produce many aches and pains in the legs, back, and neck. But the real challenges are psychological, emotional, and spiritual. Retreat can be a real test. The darkness can descend. Deep emotional issues can emerge and may even overwhelm the individual. With all these difficulties, why would anyone want to put themselves through such an ordeal and go on a meditation retreat? People go because they find that retreat produces many profound and sometimes life altering benefits.

In today’s Research News article “Isha Yoga Practices and Participation in Samyama Program are Associated with Reduced HbA1C and Systemic Inflammation, Improved Lipid Profile, and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.659667/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1645362_69_Psycho_20210525_arts_A ) Sadhasivam and colleagues recruited adult participants in a scheduled 8-day Isha yoga retreat and their spouses as controls. Retreat participants had to engage in 2 months of preparatory practices including a vegan diet daily practice of hata yoga, kriya yoga, and Shoonya meditation. In the retreat there was intensive practice. They were measured before, after, and 3-4 months later for depression, anxiety, mindfulness, joy, vitality, and resilience, diet, yoga practice, dietary restrictions, and overall health/well-being. They also had blood drawn and assayed for hemoglobin A1c (HbA1c), hemoglobin (Hb), lipid profile [cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), and triglycerides (TG)], and C-reactive protein (CRP).

They found that after the retreat and sustained 3-4 months later were significant decreased in anxiety and depression and significant increases in mindfulness, joy, vitality, resilience, blood triglycerides, and body weight. These changes did not occur in the control group. Previous research has similarly demonstrated that yoga and meditation decreases anxiety, depression, blood triglycerides and increases joy, vitality, resilience, and body weight.

The study did not have a comparable control group and as a result there are a number of possible alternative explanations for the results including participant expectancy effects. To sign up for and engage in an intensive retreat, there was likely a strong belief that the retreat would be beneficial producing a strong expectancy (placebo) effect. Future research should include a comparison to a different kind of retreat or, as has been used in other studies, a comparison to the effects of a comparable duration vacation.

The results are interesting in that the participants had considerable practice during the 2-month preparatory phase. So, the effects of the practices would be expected to be present before the retreat began. So, the improvements observed were due to participation in a 4-day intensive retreat rather than the practices themselves. The retreat involves residential living in a group and withdrawal from daily life. This has social effects and vacation-like effects of removal of life stressors. These could be responsible for the observed benefits. This supports the need for future better controlled research.

So, improve physical and mental health with an Isha yoga retreat.

“An intense 4-day guided Isha meditation retreat significantly decreased depression and anxiety while improving happiness, mindfulness, and psychological well-being.” – Senthilkumar Sadhasivam

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Sadhasivam S, Alankar S, Maturi R, Williams A, Vishnubhotla RV, Hariri S, Mudigonda M, Pawale D, Dubbireddi S, Packiasabapathy S, Castelluccio P, Ram C, Renschler J, Chang T and Subramaniam B (2021) Isha Yoga Practices and Participation in Samyama Program are Associated with Reduced HbA1C and Systemic Inflammation, Improved Lipid Profile, and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators. Front. Psychol. 12:659667. doi: 10.3389/fpsyg.2021.659667

Background: Meditation is gaining recognition as a tool to impact health and well-being. Samyama is an 8-day intensive residential meditation experience conducted by Isha Foundation requiring several months of extensive preparation and vegan diet. The health effects of Samyama have not been previously studied. The objective was to assess physical and emotional well-being before and after Samyama participation by evaluating psychological surveys and objective health biomarkers.

Methods: This was an observational study of 632 adults before and after the Isha Samyama retreat. All participants were invited to complete surveys. Controls included household significant others. Surveys were completed at baseline (T1), just before Samyama (T2), immediately after Samyama (T3), and 3 months later (T4) to assess anxiety, depression, mindfulness, joy, vitality, and resilience through validated psychometric scales. Voluntary blood sampling for biomarker analysis was done to assess hemoglobin (Hb), HbA1c, lipid profile, and C-reactive protein (CRP). Primary outcomes were changes in psychometric scores, body weight, and blood biomarkers.

Results: Depression and anxiety scores decreased from T1 to T3, with the effect most pronounced in participants with baseline depression or anxiety. Scores at T4 remained below baseline for those with pre-existing depression or anxiety. Vitality, resilience, joy, and mindfulness increased from T1 to T3 (sustained at T4). Body weight decreased by 3% from T1 to T3. Triglycerides (TG) were lower from T2 to T3. Participants had lower HbA1c and HDL at T2, and lower CRP at all timepoints compared with controls.

Conclusions: Participation in the Isha Samyama program led to multiple benefits. The 2-month preparation reduced anxiety, and participants maintained lower anxiety levels at 3 months post-retreat. Physical health improved over the course of the program as evidenced by weight loss and improved HbA1C and lipid profile. Practices associated with the Samyama preparation phase and the retreat may serve as an effective way to improve physical and mental health. Future studies may examine their use as an alternative therapy in patients with depression and/or anxiety.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.659667/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1645362_69_Psycho_20210525_arts_A

Improve Psychological, Physiological, and Epigenetic Markers of Type 2 Diabetes with Mind-Body Practices

May 12, 2021 psyjdc Leave a comment

Improve Psychological, Physiological, and Epigenetic Markers of Type 2 Diabetes with Mind-Body Practices

By John M. de Castro, Ph.D.

“Diabetes, like many other chronic diseases, can also affect the mind. Similarly the mind has great power to influence the body.” – Diabetes UK

Type 2 diabetes is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary life style. Current treatments for Type 2 Diabetes focus on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. Mindful movement practices such as Tai Chi and Qigong and yoga are mindfulness practices that are also gentle exercises. There is accumulating research on the effectiveness of these mind-body practices for the treatment of Type 2 Diabetes. So, it makes sense to examine what has been learned.

In today’s Research News article “Changes Induced by Mind-Body Intervention Including Epigenetic Marks and Its Effects on Diabetes.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865217/ ) Yang and colleagues review and summarize the published research studies of the effects of mind-body practices on the symptoms of Type 2 Diabetes including epigenetic markers.

They report that moving meditation practices such as Tai Chi and Qigong and yoga have been shown to significantly improve blood glucose, HbA1c, postprandial blood glucose, total cholesterol, and both low-density and high-density lipoprotein cholesterol. Mindfulness meditation has been shown to significantly improve HbA1c, diabetes-related distress, depression, and stress. In addition, mind-body interventions produce epigenetic changes reflected in DNA methylation modification. More study is needed but these epigenetic changes may underlie the improvements in Type 2 Diabetes produced by mind-body interventions.

Mind-body interventions have been repeatedly demonstrated to significantly reduce depression, anxiety and stress. These psychological states tend to aggravate Type 2 Diabetes. Since mind-mind-body practices reduce depression, anxiety and stress, they produce improvements in the symptoms of diabetes. In addition, mind-body practices produce physiological changes that can improve the symptoms of Type 2 Diabetes. These include activation of the parasympathetic (relaxation) nervous system, lower stress hormone (cortisol) secretion, reduced inflammation, and even reduced age based physiological changes.

These are remarkable findings that suggest that mind-body practices are effective in producing psychological and physiological changes that are very beneficial for the relief of the symptoms of Type 2 Diabetes. These benefits are reflected in changes on the epigenetic level that might ultimately be responsible for the benefits. Clearly, mind-body practices should be incorporated into Type 2 Diabetes treatment programs.

So, improve psychological, physiological, and epigenetic markers of type 2 diabetes with mind-body practices.

“meditation strategies can be useful adjunctive techniques to lifestyle modification and pharmacological management of diabetes and help improve patient wellbeing.” Gagan Priya

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Yang, H. J., Koh, E., Sung, M. K., & Kang, H. (2021). Changes Induced by Mind-Body Intervention Including Epigenetic Marks and Its Effects on Diabetes. International journal of molecular sciences, 22(3), 1317. https://doi.org/10.3390/ijms22031317

Abstract

Studies have evidenced that epigenetic marks associated with type 2 diabetes (T2D) can be inherited from parents or acquired through fetal and early-life events, as well as through lifelong environments or lifestyles, which can increase the risk of diabetes in adulthood. However, epigenetic modifications are reversible, and can be altered through proper intervention, thus mitigating the risk factors of T2D. Mind–body intervention (MBI) refers to interventions like meditation, yoga, and qigong, which deal with both physical and mental well-being. MBI not only induces psychological changes, such as alleviation of depression, anxiety, and stress, but also physiological changes like parasympathetic activation, lower cortisol secretion, reduced inflammation, and aging rate delay, which are all risk factors for T2D. Notably, MBI has been reported to reduce blood glucose in patients with T2D. Herein, based on recent findings, we review the effects of MBI on diabetes and the mechanisms involved, including epigenetic modifications.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865217/

Movement-Based Therapies are Affective for Rehabilitation from Disease

April 30, 2021 psyjdc Leave a comment

Movement-Based Therapies are Affective for Rehabilitation from Disease

By John M. de Castro, Ph.D.

“Tai chi is often described as “meditation in motion,” but it might well be called “medication in motion.” There is growing evidence that this mind-body practice, which originated in China as a martial art, has value in treating or preventing many health problems.” – Havard Health

Mindful movement practices such as yoga and Tai Chi and Qigong have been used for centuries to improve the physical and mental health and well-being of practitioners. But only recently has the effects of these practices come under scientific scrutiny. This research has been accumulating. So, it makes sense to pause and examine what has been learned about the effectiveness of these practice for rehabilitation from disease.

In today’s Research News article “Movement-Based Therapies in Rehabilitation.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476461/ ) Phuphanich and colleagues review and summarize the published research studies of the effects of mindful movement practices on rehabilitation from disease.

They report that published research has found that yoga practice reduces fatigue, sleep disturbances, depression, and anxiety and improves the immune system in cancer patients. Yoga has been found to be an effective treatment for mental health issues such as anxiety, depression, and post-traumatic stress disorder (PTSD). Yoga has been found to reduce pain levels, fear avoidance, stress, and sleep disturbance and increases self-efficacy and quality of life in chronic pain patients. Yoga has been found to improve the symptoms of traumatic brain injury, stroke, spinal cord injury, Parkinson disease, dementia, multiple sclerosis, epilepsy, and neuropathies. In addition, yoga has been found to improve systolic and diastolic blood pressures, heart rate, respiratory rate, waist circumference, waist/hip ratio, cholesterol, triglycerides, hemoglobin A1c, and insulin resistance in cardiopulmonary diseases.

They report that the published research has found that Tai Chi and Qigong practices reduce falls in the elderly. Tai Chi and Qigong has been found to reduce pain levels and increase quality of life in chronic pain patients. In addition, there is evidence that Tai Chi and Qigong practices improves depression, anxiety, posttraumatic stress disorder, sleep disturbance, schizophrenia, rheumatoid arthritis, spinal cord injury, traumatic brain injury, and immune disorders.

These are remarkable findings. The range of disorders that are positively affected by yoga, Tai Chi, and Qigong practices is breathtaking. These practices are also safe and can be widely implemented at relatively low cost and can be performed alone or in groups and at home or in a therapeutic setting. This suggests that these practices should be routinely implemented for rehabilitation from disease.

So, movement-based therapies are affective for rehabilitation from disease.

“Being mindful through any physical activity can not only improve performance in the activity such as yoga, tennis, swimming, etc, but it can also increase flexibility, confidence in movement and generate a sense of body and mind connection that has the potential for improving your overall sense of well-being.“- Anupama Kommu

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Phuphanich, M. E., Droessler, J., Altman, L., & Eapen, B. C. (2020). Movement-Based Therapies in Rehabilitation. Physical medicine and rehabilitation clinics of North America, 31(4), 577–591. https://doi.org/10.1016/j.pmr.2020.07.002

Abstract

Movement therapy refers to a broad range of Eastern and Western mindful movement-based practices used to treat the mind, body, and spirit concurrently. Forms of movement practice are universal across human culture and exist in ancient history. Research demonstrates forms of movement therapy, such as dance, existed in the common ancestor shared by humans and chimpanzees, approximately 6 million years ago. Movement-based therapies innately promote health and wellness by encouraging proactive participation in one’s own health, creating community support and accountability, and so building a foundation for successful, permanent, positive change.

Key Points – Movement-based therapies

Decrease fear avoidance and empower individuals to take a proactive role in their own health and wellness.
Can benefit patients of any ability; practices are customizable to the individual’s needs and health.
Are safe, cost-effective, and potent adjunct treatments used to supplement (not replace) standard care.
Deliver patient-centered, integrative care that accounts for the physical, psychological, social, and spiritual aspects of health and illness.
Have diverse, evidence-based benefits, including reduction in pain, stress, and debility, and improvements in range of motion, strength, balance, coordination, cardiovascular health, physical fitness, mood, and cognition.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476461/

Reduce Menopausal Symptoms with Meditation

March 16, 2021 psyjdc Leave a comment

Reduce Menopausal Symptoms with Meditation

By John M. de Castro, Ph.D.

‘midlife women with higher mindfulness scores experienced fewer menopausal symptoms,” – Dr. Richa Sood

Menopause occurs in the 40s and 50s in most women, on average at 51 years of age. It is a natural physical process that marks the end of the menstrual cycle. The symptoms that occur over the years preceding menopause include irregular periods, vaginal dryness, hot flashes, chills

night sweats, sleep problems, mood changes, weight gain and slowed metabolism, thinning hair and dry skin, and loss of breast fullness. This is a natural process that is healthy and needs to occur. So, treatments are designed for symptomatic relief and include drugs and hormone treatments. Mindfulness training including meditation is a more natural treatment that has been shown to improve the symptoms of menopause.

In today’s Research News article “A potential association of meditation with menopausal symptoms and blood chemistry in healthy women: A pilot cross-sectional study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478772/ ) Sung and colleagues recruited healthy adult women, 25-60 years of age, who were either long-term meditators or non-meditators. The particular meditation practice was a combination of focused meditation and mindful movement practice. The groups were divided into premenopausal and postmenopausal women. They were measured for menopausal symptoms, including psychological, somatic, and urogenital domains, and blood was drawn and assayed for HDL, glucose, triglyceride, total protein, creatinine, blood urea nitrogen, lactate dehydrogenase, aspartate aminotransferase, and alanine aminotransferase;

They found overall that the meditation group was lower than the non-meditators in menopausal symptoms especially depression and irritability. In the premenopausal women there was significantly higher HDL levels in the meditation group while in the postmenopausal group there were significantly higher HDL and glucose levels in the non-meditators.

This is a cross-sectional pilot study and causation cannot be definitively assigned. But these results replicates previous findings from controlled studies that mindfulness practices produce reduced menopausal symptoms, depression, and irritability. So, it is likely that the present findings are due to a causal connection between meditation practice and reduced menopausal symptoms.

So, reduce menopausal symptoms with meditation.

“Among the different natural remedies available for managing middle age, meditation for menopause has some unique benefits. It is a totally natural, completely free way to approach navigating the hormonal rollercoaster of midlife.” – Karen Shopoff Rooff

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Sung, M. K., Lee, U. S., Ha, N. H., Koh, E., & Yang, H. J. (2020). A potential association of meditation with menopausal symptoms and blood chemistry in healthy women: A pilot cross-sectional study. Medicine, 99(36), e22048. https://doi.org/10.1097/MD.0000000000022048

Abstract

Owing to hormonal changes, women experience various psychophysiological alterations over a wide age range, which may result in decreased quality of life as well as in increased risks of diseases, such as cardiovascular diseases. Although studies have been performed to research complementary methods, such as meditation, the research field still requires an adequate amount of studies for public health guidelines. This pilot cross-sectional study aims to investigate a potential association of meditation with menopausal symptoms and blood chemistry for healthy women. In this study, data of 65 healthy women (age range 25–67) including 33 meditation practitioners and 32 meditation-naïve controls were analyzed to compare the Menopausal Rating Scale scores and blood chemistry with 7 more dropouts in the blood chemistry. For blood chemistry, nine components including glucose (GLU) and high-density lipoprotein cholesterol (HDL) were measured. Two-way analysis of variance was performed by dividing the total participants into 2 groups: premenopausal and postmenopausal participants. Compared to the control group, the meditation group showed a trend of reductions in the Menopausal Rating Scale total score (P = .054) and its 2 subcomponents: depressive mood (P = .064) and irritability (P = .061). In HDL level, there was a significant interaction between group and menopausal state (P = .039) with following post hoc results: among the premenopausal participants, a significant increase in the meditation group compared to the control group (P = .005); among the control group, a significant increase in the postmenopausal compared to the premenopausal participants (P = .030). In GLU level, there was a mild interaction between group and menopausal state (P = .070) with following post hoc results: among the postmenopausal participants, a trend of increase in the control group compared to the meditation group (P = .081); among the control group, a significant increase in the postmenopausal compared to the premenopausal participants (P = .040). Our research suggests a potential association of practicing meditation with alleviations in menopausal symptoms and changes in blood chemistry, warranting further studies with a longitudinal study design and larger populations to understand the underlying causal relationships.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478772/

Improve Glucose and Lipid Metabolism with Tai Chi

March 2, 2021 psyjdc Leave a comment

Improve Glucose and Lipid Metabolism with Tai Chi

By John M. de Castro, Ph.D.

“Tai Chi exercises can improve blood glucose levels and improve the control of type 2 diabetes and immune system response.” – Anna McKenney

Diet and exercise are the typical recommendation to improve glucose and lipid metabolism for the treatment and prevention of a number of metabolic disorders. Alternatives to classical exercise programs are Tai and Qigong practices. They have been practiced for thousands of years with benefits for health and longevity. Tai Chi training is designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements.

Recently the effects of Tai Chi practice been scrutinized with empirical research. It has been found to be effective for an array of physical and psychological issues. It appears to strengthen the immune system, reduce inflammation, increase the number of cancer killing cells in the bloodstream and improve cardiovascular function. In addition, they appear to be effective in improving blood glucose and lipid metabolism. Because Tai Chi is not strenuous, involving slow gentle movements, and is safe, having no appreciable side effects, it is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. But most studies of Tai Chi benefits have employed lengthy practices. The acute, immediate, effects of a session of Tai Chi have not been well investigated.

In today’s Research News article “Effect of a Single Session of Tai Chi Chuan Practice on Glucose and Lipid Metabolism and Related Hormones.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460509/ ) Lu and colleagues recruited healthy adults over 50 years of age who were Tai Chi practitioners and a group of non-practitioners who were equivalent in age, gender, and body size. The Tai Chi group performed one 40-minute Tai Chi practice while the control group rested for 40 minutes. They obtained blood samples from both groups before and after their sessions and measured them for total cholesterol, blood glucose, insulin, insulin resistance, insulin sensitivity, and endothelin-1 (ET-1, a vasoconstrictor).

They found that at baseline, before practice, the Tai Chi group in comparison to the control group at rest had significantly lower levels of total cholesterol, insulin, insulin resistance, while insulin sensitivity was significantly higher. In comparison to the control group the Tai Chi group had a significantly greater percentage increases from baseline in blood glucose, insulin, and insulin resistance and a significantly larger percentage decreases in total cholesterol, HDL cholesterol, insulin sensitivity, and endothelin-1 (ET-1).

These are interesting results that must be tempered with the understanding that the control condition was not active. So, the changes seen after Tai Chi practice may have been due to exercise effects rather than performing Tai Chi itself. Indeed, the results on the immediate acute effects of Tai Chi practice on glucose and lipid metabolism are complicated and difficult to interpret. This may be due to the lack of an active control, comparison, condition, revealing the effects of activity vs. rest rather than effects specific to Tai Chi.

But the baseline results are not contaminated and they suggest that the practice of Tai Chi produces a general improvement in glucose and fat metabolism that is present even without immediate practice. This suggests that Tai Chi practice improves the overall physiological health of the practitioners. This would lead to lower likelihood of diabetes or cardiovascular disease and improvements in the diseases if present. Indeed Tai Chi practice has been found to be beneficial, improving symptoms, for people with diabetes and also cardiovascular disease.

So, improve glucose and lipid metabolism with Tai Chi.

“Diet and exercise are the cornerstone of diabetes management. People with diabetes who exercise regularly have better control over their blood glucose levels and fewer complications such as heart disease and stroke. Many people, however, are unable to keep up with their regular exercise because they either don’t enjoy it, or have a problem finding time to exercise. Tai chi offers a major advantage: It’s enjoyable, and to many, it’s almost addictive.” – Paul Lam

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Lu, W. A., Chen, Y. S., Wang, C. H., & Kuo, C. D. (2020). Effect of a Single Session of Tai Chi Chuan Practice on Glucose and Lipid Metabolism and Related Hormones. Life (Basel, Switzerland), 10(8), 145. https://doi.org/10.3390/life10080145

Abstract

Background: To examine the effect of Tai Chi Chuan (TCC) practice on glucose and lipid metabolism and related hormones in TCC practitioners. Methods: Twenty-one TCC practitioners and nineteen healthy controls were included in this study. Classical Yang’s TCC was practiced by the TCC practitioners. The percentage changes in serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), serum glucose (SG), serum insulin, serum insulin level, homeostatic model assessment of insulin resistance (HOMA-IR), log(HOMA-IR), quantitative insulin sensitivity check index (QUICKI), and serum endothelin-1 (ET-1) before and 30 min after resting or TCC practice were compared between healthy controls and TCC practitioners. Results: Before TCC or resting, the serum insulin level, HOMA-IR, and log(HOMA-IR) of the TCC practitioners were significantly lower than those of healthy subjects, whereas the QUICKI of the TCC practitioners was significantly higher than that of healthy subjects. Thirty min after TCC practice, the %TC, %HDL-C, %QUICKI, and %ET-1 were all significantly decreased, whereas the %SG, %serum insulin, and %HOMA-IR were significantly increased in the TCC group as compared to the control group 30 min after resting. Conclusions: The serum glucose, insulin level and insulin resistance were enhanced, whereas the cholesterol, HDL-C and ET-1 levels were reduced 30 min after TCC practice. The mechanism underlying these effects of TCC 30 min after TCC is not clear yet.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460509/