Improve Bipolar Disorder with Mindfulness

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Improve Bipolar Disorder with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness looks like a potentially effective way of managing bipolar disorder, especially the depressive pole, which may be the most difficult to treat with medication alone. Mindfulness exercises and meditations are useful for people with bipolar disorder (manic depression) because mindfulness decreases the relapse rate for depression, reduces stress and anxiety, which contribute significantly to the onset of both mania and depression and may worsen the course of the illness, and improves a person’s ability to manage thoughts and feelings and increases awareness of the way the person tends to internalize external stimuli.” – Shamash Alidina

 

Bipolar Disorder, also known as Manic Depressive Disorder, is a mood disorder characterized by alternating states of extreme depression, relative normalcy, and extreme euphoria (mania). The symptoms of depression and mania are so severe that the individual is debilitated and unable to conduct their normal daily lives. The depression is so severe that suicide occurs in about 1% of cases of Bipolar Disorder. It is thought to result from imbalances in the monoamine neurotransmitter systems in the nervous system and appears to be highly linked to the genes. There are great individual differences in Bipolar Disorder. The extreme mood swings can last for a few days to months and can occur only once or reoccur frequently.

 

Bipolar Disorder affects about 1% of the population throughout the world at any time. But about 3% to 10% of the population may experience it sometime during their lives. It is usually treated with drugs. But, these medications are not always effective and can have difficult side effects. Hence, there is a great need for alternative treatments. Mindfulness practices and treatments have been shown to be effective for major mental disorders, including depression and anxiety disorders and to improve the regulation of emotions. Mindfulness-Based Cognitive Therapy (MBCT) was specifically developed for the treatment of depression and has been shown to be very effective. MBCT involves mindfulness training, containing sitting and walking meditation and body scan, and cognitive therapy to alter how the patient relates to the thought processes that often underlie and exacerbate psychological symptoms. So, MBCT may be a safe and effective treatment for Bipolar Disorder.

 

In today’s Research News article “Mindfulness-Based Treatment for Bipolar Disorder: A Systematic Review of the Literature.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590538/, Bojic and Becerra reviewed and summarized the published research literature on the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for the treatment of Bipolar Disorder. They identified 13 published research studies.

 

They report that the published research finds that MBCT in conjunction with drug treatments produces significant improvements in most of the symptoms of Bipolar Disorder. MBCT  was found to produce significant improvements in mood, including decreased mania, anxiety, and depression. In addition, there were significant increases in the patients’ ability to regulate their emotions and their ability to think clearly (cognitive abilities). The studies report that MBCT remains effective one year after the conclusion of treatment.

 

Thus the current state of the research suggests that Mindfulness-Based Cognitive Therapy (MBCT) is a safe, effective, and lasting treatment for Bipolar Disorder when used in addition to the standard drug treatments. These are important and exciting findings. They suggest that MBCT can help to relieve the suffering and improve the patients ability to conduct their lives.

 

So, improve bipolar disorder with mindfulness.

 

“The extreme highs and lows of bipolar disorder can be difficult to cope with, and difficult for those around you. The disorder causes anxiety at one end and depression at the other. Meditation is an easy and natural method for relaxing and reducing stress in anyone, and particularly in people with bipolar disorder.” – Anthony Watt

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Bojic, S., & Becerra, R. (2017). Mindfulness-Based Treatment for Bipolar Disorder: A Systematic Review of the Literature. Europe’s Journal of Psychology, 13(3), 573–598. http://doi.org/10.5964/ejop.v13i3.1138

 

Abstract

Despite the increasing number of studies examining the effects of mindfulness interventions on symptoms associated with Bipolar Disorder (BD), the effectiveness of this type of interventions remains unclear. The aim of the present systematic review was to (i) critically review all available evidence on Mindfulness Based Cognitive Therapy (MBCT) as a form of intervention for BD; (ii) discuss clinical implications of MBCT in treating patients with BD; and (iii) provide a direction for future research. The review presents findings from 13 studies (N = 429) that fulfilled the following selection criteria: (i) included BD patients; (ii) presented results separately for BD patients and control groups (where a control group was available); (iii) implemented MBCT intervention; (iv) were published in English; (v) were published in a peer reviewed journal; and (vi) reported results for adult participants. Although derived from a relatively small number of studies, results from the present review suggest that MBCT is a promising treatment in BD in conjunction with pharmacotherapy. MBCT in BD is associated with improvements in cognitive functioning and emotional regulation, reduction in symptoms of anxiety depression and mania symptoms (when participants had residual manic symptoms prior to MBCT). These, treatment gains were maintained at 12 month follow up when mindfulness was practiced for at least 3 days per week or booster sessions were included. Additionally, the present review outlined some limitations of the current literature on MBCT interventions in BD, including small study sample sizes, lack of active control groups and idiosyncratic modifications to the MBCT intervention across studies. Suggestions for future research included focusing on factors underlying treatment adherence and understanding possible adverse effects of MBCT, which could be of crucial clinical importance.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590538/

Treat Physical Health Conditions with Mindfulness

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Treat Physical Health Conditions with Mindfulness

 

By John M. de Castro, Ph.D.

 

“A growing body of research now links the Eastern practice to improved conditions for serious ailments, from diabetes to heart disease to cancer. How? By “treating the whole person… so they can live in greater health and joy.” – Shauna Shapiro

 

Mindfulness training has been shown through extensive research to be effective in improving physical and psychological health and particularly with the physical and psychological reactions to stress. Techniques such as Mindfulness Training, Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT) as well as Yoga practice and Tai Chi or Qigong practice have been demonstrated to be effective. This has led to an increasing adoption of these mindfulness techniques for the health and well-being of both healthy and ill individuals.

 

The vast majority of the mindfulness training techniques, however, require a certified trained therapist. This produces costs that many clients can’t afford. In addition, the participants must be available to attend multiple sessions at particular scheduled times that may or may not be compatible with their busy schedules and at locations that may not be convenient. As an alternative, on-line mindfulness training programs have been developed. These have tremendous advantages in decreasing costs, making training schedules much more flexible, and eliminating the need to go repeatedly to specific locations. But, the question arises as to the effectiveness of these programs.

 

In today’s Research News article “Web-Based Mindfulness Interventions for People With Physical Health Conditions: Systematic Review.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599726/, Toivonen and colleagues review and summarize the published research literature on the effectiveness on on-line mindfulness training programs on the psychological and physical symptoms of chronic diseases. They report on 16 published studies.

 

They found that studies of on-line mindfulness training for the treatment of chronic pain conditions, including fibromyalgia, demonstrated significant effectiveness for pain coping and the psychological symptoms produced by chronic pain. But, the evidence was inconclusive regarding alterations of experienced pain. Studies of heart disease treatment with on-line mindfulness trainings demonstrated small improvements relative to usual care in exercise tolerance, heart rate, systolic blood pressure, and stress. Studies of Irritable Bowel Syndrome (IBS) demonstrated significant effectiveness of on-line mindfulness trainings for the symptoms, quality of life, and psychological distress produced by IBS. Studies of epilepsy demonstrated significant effectiveness of on-line mindfulness trainings for the depression accompanying epilepsy. Studies of Tinnitus demonstrated significant effectiveness of on-line mindfulness trainings for Tinnitus severity, depression, anxiety and perceived stress accompanying Tinnitus. Studies of acquired brain injury demonstrated significant effectiveness of on-line mindfulness trainings for the mental fatigue accompanying acquired brain injury. Studies of cancer survivors demonstrated significant effectiveness of on-line mindfulness trainings for the fatigue, depressed mood, and psychological distress accompanying cancer survival.

 

The published studies found that it did not make a significant difference if the on-line mindfulness training occurred through immediate interaction or with continuously available resources or whether there was an active facilitator or not. Hence, on-line training did not require active participation by a therapist. Effectiveness was present regardless. The materials and not the format or the therapist was important.

 

These are important and exciting results that demonstrate the effectiveness of on-line mindfulness training for the treatment of chronic diseases. Thus, mindfulness trainings can be implemented with high cost-effectiveness, to large numbers of people, without the necessity of a therapist’s involvement, and without the requirement for attendance at particular locations. The results suggest that mindfulness practices can be provided widely and inexpensively to relieve at least some of the suffering produced by a wide variety of chronic diseases.

 

“Other research has looked broadly at use of mindfulness-based group therapy compared to individual cognitive-behavioral therapy for patients with various conditions including depression, anxiety and stress and adjustment disorders. They found that the mindfulness group therapy as effective as the individual therapy.” – American Psychiatric Association

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Toivonen, K. I., Zernicke, K., & Carlson, L. E. (2017). Web-Based Mindfulness Interventions for People With Physical Health Conditions: Systematic Review. Journal of Medical Internet Research, 19(8), e303. http://doi.org/10.2196/jmir.7487

 

Abstract

Background

Mindfulness-based interventions (MBIs) are becoming increasingly popular for helping people with physical health conditions. Expanding from traditional face-to-face program delivery, there is growing interest in Web-based application of MBIs, though Web-based MBIs for people with physical health conditions specifically have not been thoroughly reviewed to date.

Objective

The objective of this paper was to review Web-based MBIs for people with physical health conditions and to examine all outcomes reported (eg, efficacy or effectiveness for physical changes or psychological changes; feasibility).

Methods

Databases PubMed, PsycINFO, Science Direct, CINAHL Plus, and Web of Science were searched. Full-text English papers that described any Web-based MBI, examining any outcome, for people with chronic physical health conditions were included. Randomized, nonrandomized, controlled, and uncontrolled trials were all included. Extracted data included intervention characteristics, population characteristics, outcomes, and quality indicators. Intervention characteristics (eg, synchronicity and guidance) were examined as potential factors related to study outcomes.

Results

Of 435 publications screened, 19 published papers describing 16 studies were included. They examined Web-based MBIs for people with cancer, chronic pain or fibromyalgia, irritable bowel syndrome (IBS), epilepsy, heart disease, tinnitus, and acquired brain injury. Overall, most studies reported positive effects of Web-based MBIs compared with usual care on a variety of outcomes including pain acceptance, coping measures, and depressive symptoms. There were mixed results regarding the effectiveness of Web-based MBIs compared with active control treatment conditions such as cognitive behavioral therapy. Condition-specific symptoms (eg, cancer-related fatigue and IBS symptoms) targeted by treatment had the largest effect size improvements following MBIs. Results are inconclusive regarding physical variables.

Conclusions

Preliminary evidence suggests that Web-based MBIs may be helpful in alleviating symptom burden that those with physical health conditions can experience, particularly when interventions are tailored for specific symptoms. There was no evidence of differences between synchronous versus asynchronous or facilitated versus self-directed Web-based MBIs. Future investigations of Web-based MBIs should evaluate the effects of program adherence, effects on mindfulness levels, and whether synchronous or asynchronous, or facilitated or self-directed interventions elicit greater improvements.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599726/

Improve Alzheimer’s Disease Risk Factors with Mindfulness

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Improve Alzheimer’s Disease Risk Factors with Mindfulness

 

By John M. de Castro, Ph.D.

 

“MBSR may reduce hippocampal atrophy and improve functional connectivity in the same areas of the brain most affected by Alzheimer’s disease. MBSR is a relatively simple intervention, with very little downside that may provide real promise for these individuals who have very few treatment options.” – Rebecca Wells

 

In the course of normal aging, there is a slow decline in cognitive ability. But, for some the decline can be excessive producing dementia. Alzheimer’s disease is the most common form of dementia. It involves an irreversible progressive loss of mental function associated with brain degeneration. The early stages are typified by memory loss but as the disease progresses patients can lose the ability to carry on a conversation or carry on normal life functions, and eventually leads to death. In fact, Alzheimer’s disease is the sixth leading cause of death in the U.S. On average, this progression lasts about 8 years but can last as long as 20 years. Alzheimer’s typically first emerges after age 65, but can occur at younger ages.

 

It is estimated that 5 million Americans have Alzheimer’s disease. Unfortunately, there are no known cures for Alzheimer’s disease. But, there are treatments that can help relieve the symptoms. These include drug treatments. Recently, mindfulness practices have been shown to improve the symptoms of age related dementia. It has been shown that chronic stress is a risk factor for the development of Alzheimer’s disease. Mindfulness-Based Stress Reduction (MBSR) is a mindfulness technique that was designed to reduce stress and its effects. So, it would seem reasonable to study the ability of MBSR to relieve the symptoms of Alzheimer’s disease.

 

In today’s Research News article “Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537638/, Ashton and colleagues examined the association of a biomarker, repressor element 1-silencing transcription (REST), with Alzheimer’s disease and the ability of Mindfulness-Based Stress Reduction (MBSR) to alter REST and the early symptoms of Alzheimer’s disease. They recruited patients over 65 years of age with diagnosed Alzheimer’s disease and healthy elderly control participants. They scanned their brains with Magnetic Resonance Imaging (MRI) and collected blood samples to measure the plasma levels of REST. They also recruited individuals over 65 years of age with anxiety, depression, and mild cognitive impairment. They were randomly assigned to receive an 8-week program of either MBSR or health education. They measured memory, verbal fluency, executive function, anxiety, depression, worry, and collected blood samples to measure the plasma levels of REST.

 

They found that REST levels were significantly lower in Alzheimer’s disease patients than healthy control participants. Also, the lower the levels of REST the lower the brain volumes in these patients. In addition, the REST levels in participants with mild cognitive impairment who later expressed full blown Alzheimer’s disease were significantly lower than those participants who did not. MBSR produced a significant increase in REST and the greater the level of REST increase the greater the improvement in anxiety and depression.

 

These are very interesting and potentially important findings that suggest that levels of repressor element 1-silencing transcription (REST) in the blood may be a marker for Alzheimer’s disease. It is lower in patients with active Alzheimer’s disease and in people with mild cognitive impairment who would eventually develop Alzheimer’s disease and is associated with reduced brain volume. MBSR participation increases REST and the increase is associated with improved symptoms. This suggests that low REST levels identify Alzheimer’s disease patients and that mindfulness practice can increase REST levels.

 

Repressor element 1-silencing transcription (REST) promotes the development of neurons. So, low levels of REST may be a sign that neural development has slowed or stopped and this may be an important mechanism for the development of Alzheimer’s disease. Interestingly, mindfulness training may be able to reverse the decline in REST and could potentially restrain the development of the disease. It is not known how MBSR could affect REST, but it can be speculated that the ability of MBSR to reduce the physiological and psychological responses to stress may be involved.

 

So, improve Alzheimer’s disease risk factors with mindfulness.

 

“Perceived stress can be altered by mindfulness-based stress reduction, cognitive-behavioural therapies and stress-reducing drugs. These interventions may postpone or even prevent an individual’s cognitive decline.” – Mindy Katz

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Ashton, N. J., Hye, A., Leckey, C. A., Jones, A. R., Gardner, A., Elliott, C., … Marchant, N. L. (2017). Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population. Translational Psychiatry, 7(6), e1148–. http://doi.org/10.1038/tp.2017.113

 

Abstract

The repressor element 1-silencing transcription (REST) factor is a key regulator of the aging brain’s stress response. It is reduced in conditions of stress and Alzheimer’s disease (AD), which suggests that increasing REST may be neuroprotective. REST can be measured peripherally in blood plasma. Our study aimed to (1) examine plasma REST levels in relation to clinical and biological markers of neurodegeneration and (2) alter plasma REST levels through a stress-reduction intervention—mindfulness training. In study 1, REST levels were compared across the following four well-characterized groups: healthy elderly (n=65), mild cognitive impairment who remained stable (stable MCI, n=36), MCI who later converted to dementia (converter MCI, n=29) and AD (n=65) from the AddNeuroMed cohort. REST levels declined with increasing severity of risk and impairment (healthy elderly>stable MCI>converter MCI>AD, F=6.35, P<0.001). REST levels were also positively associated with magnetic resonance imaging-based hippocampal and entorhinal atrophy and other putative blood-based biomarkers of AD (Ps<0.05). In study 2, REST was measured in 81 older adults with psychiatric risk factors for AD before and after a mindfulness-based stress reduction intervention or an education-based placebo intervention. Mindfulness-based training caused an increase in REST compared with the placebo intervention (F=8.57, P=0.006), and increased REST was associated with a reduction in psychiatric symptoms associated with stress and AD risk (Ps<0.02). Our data confirm plasma REST associations with clinical severity and neurodegeneration, and originally, that REST is modifiable by a psychological intervention with clinical benefit.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537638/

Improve Post-Traumatic Stress Disorder in Combat Veterans with Mindfulness

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Improve Post-Traumatic Stress Disorder in Combat Veterans with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness-based approaches have been shown to be useful for problems commonly seen in trauma survivors such as anxiety and hyperarousal. Mindfulness practice has potential to be of benefit to individuals with PTSD, either as a tertiary or a stand-alone treatment.” – National Center for PTSD

 

Experiencing trauma is quite common. It has been estimated that 60% of men and 50% of women will experience a significant traumatic event during their lifetime. But, only a fraction will develop Post-Traumatic Stress Disorder (PTSD). But this still results in a frightening number of people with 7%-8% of the population developing PTSD at some point in their life. For military personnel, it’s much more likely for PTSD to develop with about 11% – 20% of those who have served in a war zone developing PTSD.

 

PTSD involves a number of troubling symptoms including reliving the event with the same fear and horror in nightmares or with a flashback. PTSD sufferers avoid situations that remind them of the event this may include crowds, driving, movies, etc. and may avoid seeking help because it keeps them from having to think or talk about the event. They often experience negative changes in beliefs and feelings including difficulty experiencing positive or loving feelings toward other people, avoiding relationships, memory difficulties, or see the world as dangerous and no one can be trusted. Sufferers may feel hyperarousal, feeling keyed up and jittery, or always alert and on the lookout for danger. They may experience sudden anger or irritability, may have a hard time sleeping or concentrating, may be startled by a loud noise or surprise.

 

Obviously, these are troubling symptoms that need to be addressed. There are a number of therapies that have been developed to treat PTSD. One of which, mindfulness training has been found to be particularly effective. Mindfulness Based Stress Reduction (MBSR) has been found to improve PTSD symptoms. MBSR involves a combination of mindfulness practices including, meditation, body scan, and yoga. In today’s Research News article “A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574875/, Bremner and colleagues examine the effectiveness of Mindfulness Based Stress Reduction (MBSR) for the treatment of PTSD in combat veterans.

 

They recruited combat veterans from the wars in Iraq and randomly assigned them to receive either an 8-week program of Mindfulness Based Stress Reduction (MBSR) or Present-Centered Group Therapy (PCGT). PCGT involved 8-weeks of psycho-education and group discussion of present day problems. They were measured before and after treatment and 6 months later for PTSD symptoms, psychiatric issues, mindfulness, and spiritual well-being. The veterans also underwent a Positron Emission Tomography (PET) brain scan while viewing pictures of the Iraq war or neutral pictures.

 

They found that MBSR, but not the control PCGT condition, produced significant reductions in PTSD symptoms, particularly avoidance and hyperarousal, and increases in mindfulness that were maintained even 6-months after the end of treatment. All of the veterans showed increased activation in frontal and temporal cortical regions and decreased activation in subcortical areas when viewing combat related pictures. After MBSR, in comparison to baseline and the control group, the veterans had significantly increased activation of the anterior cingulate and inferior parietal cortex, and decreased activation in the insula and precuneus. Activation of the anterior cingulate cortex is associated with improved emotion regulation and has been previously associated with relief of trauma symptoms while decreased activity in the insula has been associated with decreases in hyperarousal.

 

The results of this pilot study are interesting and potentially important. The study is unusual in that it had an active control condition that improves the strength of the conclusions. The results demonstrate that Mindfulness Based Stress Reduction (MBSR) produces lasting improvements in PTSD symptoms in combat veterans. They also show that MBSR produces changes in the nervous system areas that may underlie the symptoms. Hence, MBSR appears to be a safe and effective treatment of Post-Traumatic Stress Disorder (PTSD) that can relieve the suffering resulting from trauma.

 

So, improve post-traumatic stress disorder in combat veterans with mindfulness.

 

“Mindfulness-based stress reduction approaches are likely to work just as well for non-veterans who have been exposed to civilian traumas such as physical or sexual assaults.” Alan Peterson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Bremner, J. D., Mishra, S., Campanella, C., Shah, M., Kasher, N., Evans, S., … Carmody, J. (2017). A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder. Frontiers in Psychiatry, 8, 157. http://doi.org/10.3389/fpsyt.2017.00157

 

Abstract

Objective

Brain imaging studies in patients with post-traumatic stress disorder (PTSD) have implicated a circuitry of brain regions including the medial prefrontal cortex, amygdala, hippocampus, parietal cortex, and insula. Pharmacological treatment studies have shown a reversal of medial prefrontal deficits in response to traumatic reminders. Mindfulness-based stress reduction (MBSR) is a promising non-pharmacologic approach to the treatment of anxiety and pain disorders. The purpose of this study was to assess the effects of MBSR on PTSD symptoms and brain response to traumatic reminders measured with positron-emission tomography (PET) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) combat veterans with PTSD. We hypothesized that MBSR would show increased prefrontal response to stress and improved PTSD symptoms in veterans with PTSD.

Method

Twenty-six OEF/OIF combat veterans with PTSD who had recently returned from a combat zone were block randomized to receive eight sessions of MBSR or present-centered group therapy (PCGT). PTSD patients underwent assessment of PTSD symptoms with the Clinician-Administered PTSD Scale (CAPS), mindfulness with the Five Factor Mindfulness Questionnaire (FFMQ) and brain imaging using PET in conjunction with exposure to neutral and Iraq combat-related slides and sound before and after treatment. Nine patients in the MBSR group and 8 in the PCGT group completed all study procedures.

Results

Post-traumatic stress disorder patients treated with MBSR (but not PCGT) had an improvement in PTSD symptoms measured with the CAPS that persisted for 6 months after treatment. MBSR also resulted in an increase in mindfulness measured with the FFMQ. MBSR-treated patients had increased anterior cingulate and inferior parietal lobule and decreased insula and precuneus function in response to traumatic reminders compared to the PCGT group.

Conclusion

This study shows that MBSR is a safe and effective treatment for PTSD. Furthermore, MBSR treatment is associated with changes in brain regions that have been implicated in PTSD and are involved in extinction of fear responses to traumatic memories as well as regulation of the stress response.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574875/

Reduce Fatigue with Breast Cancer with Yoga

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Reduce Fatigue with Breast Cancer with Yoga

 

By John M. de Castro, Ph.D.

 

“Yoga works on the principle of mind and body health and it would help women cope with systemic therapy side effects better. Yoga nidra and pranayama also improve sleep patterns. Thus, all this together may reduce fatigue and pain.” – Nita Nair

 

Because of great advances in treatment, many women today are surviving breast cancer. But, cancer survivors frequently suffer from anxiety, depression, mood disturbance, post-traumatic stress disorder (PTSD), sleep disturbance, fatigue, sexual dysfunction, loss of personal control, impaired quality of life, an alteration of their body image, and psychiatric symptoms which have been found to persist even ten years after remission. Also, breast cancer survivors can have to deal with a heightened fear of reoccurrence. This is particularly true with metastatic cancer. So, safe and effective treatments for the symptoms in breast cancer and the physical and psychological effects of the treatments are needed.

 

Mindfulness training has been shown to help with general cancer recovery and breast cancer recovery. Yoga practice of has also been shown to be helpful with the residual symptoms, the psychological and physical ability to deal with cancer treatment and improves sleep in women with metastatic breast cancer. So, it’s reasonable to further explore the potential benefits of yoga practice to relieve fatigue and stress in women fighting metastatic breast cancer.

 

In today’s Research News article “Effects of Yoga in Managing Fatigue in Breast Cancer Patients: A Randomized Controlled Trial.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545948/, Vadiraja and colleagues recruited women with advanced metastatic breast cancer. They received treatment as usual and were randomly assigned to receive either education and supportive counseling or an integrated yoga program for 12 weeks consisting of 60-min sessions twice a week combined with home practice of relaxation, breathing exercises, postures, and meditation. They were measured before and after treatment for perceived stress and fatigue.

 

In comparison to baseline and the control group the yoga practice group had significant reductions in perceived stress and in fatigue, including severity, how often they felt fatigued, how much fatigue interfered with their everyday activities, and the difference between daytime and nighttime fatigue.  It would have been better if the control group had performed some other form of exercise to determine if it was yoga practice per se or simply exercise was responsible for the results. In addition, since the integrated yoga program contained multiple components it is impossible to differentiate which or which combination of components was effective. Nevertheless, these are impressive and exciting results that integrated yoga practice can have such positive effects on women with advanced metastatic breast cancer.

 

Mindfulness practices, including yoga practice, has been shown to reduce the physiological and psychological responses to stress and fatigue in other populations. It is particularly good that yoga has these effects in women with cancer where stress and fatigue exacerbate an already difficult situation. These effects may help to contribute to these women’s ability to fight off the cancer and improve their longevity.

 

So, reduce fatigue with breast cancer with yoga.

 

“Even on my worst days, in terms of fatigue, if I just got up and did a little something, whether it be some light stretching, gentle yoga, just some yoga, that definitely made me feel better.” – Amy Schnitzler

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Vadiraja, H., Rao, R. M., Nagarathna, R., Nagendra, H., Patil, S., Diwakar, R. B., … Ajaikumar, B. (2017). Effects of Yoga in Managing Fatigue in Breast Cancer Patients: A Randomized Controlled Trial. Indian Journal of Palliative Care, 23(3), 247–252. http://doi.org/10.4103/IJPC.IJPC_95_17

 

Abstract

Background:

Cancer-related fatigue is widely prevalent in cancer patients and affects quality of life in advanced cancer patients. Fatigue is caused due to both psychologic distress and physiological sequel following cancer progression and its treatment. In this study, we evaluate the effects of yogic intervention in managing fatigue in metastatic breast cancer patients.

Methods:

Ninety-one patients with metastatic breast cancer were randomized to receive integrated yoga program (n = 46) or supportive therapy and education (n = 45) over a 3-month period. Assessments such as perceived stress, fatigue symptom inventory, diurnal salivary cortisol, and natural killer cell counts were carried out before and after intervention. Analysis was done using an intention-to-treat approach. Postmeasures for the above outcomes were assessed using ANCOVA with respective baseline measure as a covariate.

Results:

The results suggest that yoga reduces perceived stress (P = 0.001), fatigue frequency (P < 0.001), fatigue severity (P < 0.001), interference (P < 0.001), and diurnal variation (P < 0.001) when compared to supportive therapy. There was a positive correlation of change in fatigue severity with 9 a.m. salivary cortisol levels.

Conclusion:

The results suggest that yoga reduces fatigue in advanced breast cancer patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545948/

Improve the Physical and Psychological Condition of Breast Cancer Patients with Yoga

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Improve the Physical and Psychological Condition of Breast Cancer Patients with Yoga

 

By John M. de Castro, Ph.D.

 

“Studies suggest that doing yoga while going through breast cancer treatment helps you get through it with fewer side effects. Often doctors have to stop chemo or lower doses to levels that may not be as effective because people don’t tolerate the side effects. But yoga appears to decrease all kinds of side effects.” – Timothy McCall

 

About 12.5% of women in the U.S. develop invasive breast cancer over their lifetimes and every year about 40,000 women die. Indeed, more women in the U.S. die from breast cancer than from any other cancer, besides lung cancer. Breast cancer diagnosis, however, is not a death sentence. Death rates have been decreasing for decades from improved detection and treatment of breast cancer. Five-year survival rates are now at around 95%. The improved survival rates mean that more women are now living with cancer.

 

Cancer treatment involving surgery and radiation therapy and/or chemotherapy is extremely difficult physically and emotionally. In addition, surviving cancer, however, carries with it a number of problems. “Physical, emotional, and financial hardships often persist for years after diagnosis and treatment. Cancer survivors are also at greater risk for developing second cancers and other health conditions.” (National Cancer Survivors Day). Also, breast cancer survivors can have to deal with a heightened fear of reoccurrence, and an alteration of their body image. Additionally, cancer survivors frequently suffer from anxiety, depression, mood disturbance, Post-Traumatic Stress Disorder (PTSD), sleep disturbance, fatigue, sexual dysfunction, loss of personal control, impaired quality of life, and psychiatric symptoms which have been found to persist even ten years after remission. So, safe and effective treatments for the symptoms in breast cancer and the physical and psychological effects of the treatments are needed.

 

Mindfulness training has been shown to help with general cancer recovery and breast cancer recovery. Mindfulness helps to alleviate many of the residual physical and psychological symptoms, including stress,  sleep disturbance, and anxiety and depression. The mindfulness practice of Yoga has also been shown to be helpful with the residual symptoms. So, it’s reasonable to further explore the potential benefits of yoga practice for women during and after treatment.

 

In today’s Research News article “Salute to the sun: a new dawn in yoga therapy for breast cancer.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587658/, Galliford and colleagues reviewed and summarized the published research studies of the application of yoga therapy or Mindfulness-Based Stress Reduction (MBSR), which contains yoga, for women with breast cancer. They found 38 published studies. They report that the research fids that yoga is effective in improving emotion regulation, quality of life, sleep quality, lymphatic system integrity, and social functioning, and decreasing anxiety, depression, and stress hormones (cortisol).

 

These are important findings that are fairly consistent across a variety of studies. The research clearly suggests that practicing yoga can benefit the social, psychological, and physical functioning of women with breast cancer. These are important benefits that suggest that yoga practice may improve women’s ability to fight breast cancer and maintain health and improve overall well-being.

 

So, improve the physical and psychological condition of breast cancer patients with yoga.

 

”For women with breast cancer, research shows those who practice yoga may also have less stress and fatigue, and better quality of life.” – Stacy Simon

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Galliford, M., Robinson, S., Bridge, P., & Carmichael, M. (2017). Salute to the sun: a new dawn in yoga therapy for breast cancer. Journal of Medical Radiation Sciences, 64(3), 232–238. http://doi.org/10.1002/jmrs.218

 

Abstract

Introduction

Interest in the application of yoga for health benefits in western medicine is growing rapidly, with a significant rise in publications. The purpose of this systematic review is to determine whether the inclusion of yoga therapy to the treatment of breast cancer can improve the patient’s physical and psychosocial quality of life (QoL).

Methods

A search of peer reviewed journal articles published between January 2009 and July 2014 was conducted. Studies were included if they had more than 15 study participants, included interventions such as mindfulness‐based stress reduction (MBSR) or yoga therapy with or without comparison groups and had stated physical or psychological outcomes.

Results

Screening identified 38 appropriate articles. The most reported psychosocial benefits of yoga therapy were anxiety, emotional and social functioning, stress, depression and global QoL. The most reported physical benefits of yoga therapy were improved salivary cortisol readings, sleep quality and lymphocyte apoptosis. Benefits in these areas were linked strongly with the yoga interventions, in addition to significant improvement in overall QoL.

Conclusion

The evidence supports the use of yoga therapy to improve the physical and psychosocial QoL for breast cancer patients with a range of benefits relevant to radiation therapy. Future studies are recommended to confirm these benefits. Evidence‐based recommendations for implementation of a yoga therapy programme have been derived and included within this review. Long‐term follow‐up is necessary with these programmes to assess the efficacy of the yoga intervention in terms of sustainability and patient outcomes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587658/

Mindfulness Decreases the Impact of Abusive Supervision at Work

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Mindfulness Decreases the Impact of Abusive Supervision at Work

 

By John M. de Castro, Ph.D.

 

“Mindfulness has stopped many workplace snafus from happening in the first place. Once the mind is calm, a resolution can be reached.” – Diane Dye Hansen

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. How we spend that time is immensely important for our psychological and physical health. Indeed, the work environment has even become an important part of our social lives, with friendships and leisure time activities often attached to the work environment. But, more than half of employees in the U.S. and nearly 2/3 worldwide are unhappy at work. This is partially due to work-related stress which is epidemic in the western workplace. Almost two thirds of workers reporting high levels of stress at work. This stress can result in impaired health and can result in burnout; producing fatigue, cynicism, and professional inefficacy.

 

To help overcome unhappiness, stress, and burnout, mindfulness practices have been implemented in the workplace. Indeed, mindfulness practices have been shown to markedly reduce the physiological and psychological responses to stress. As a result, it has become very trendy for business to incorporate meditation into the workday to help improve employee well-being, health, and productivity. For example, Google offers “Search Inside Yourself” classes to teach mindfulness at work. But, although there is a lot of anecdotal evidence of meditation improving well-being and work performance, there is actually very little systematic research on mindfulness’ effectiveness at work. In addition, there is no information on the effectiveness of mindfulness to help overcome the effects of a hostile work environment.

 

In today’s Research News article “The Buffering Effect of Mindfulness on Abusive Supervision and Creative Performance: A Social Cognitive Framework.” See summary below or view the full text of the study at: http://journal.frontiersin.org/article/10.3389/fpsyg.2017.01588/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_398354_69_Psycho_20170921_arts_A, Zheng and Liu recruited employees and managers from an electronics manufacturer. They had them complete measures of abusive supervision, mindfulness, self-efficacy. The supervisors also rated them for their levels of creative performance at work.

 

They found, as expected, that the higher the level of abusive supervision, the lower the level of self-efficacy and creativity and the higher the level of self-efficacy the greater the level of creativity. Further, they found that employees who were low in mindfulness were severely impacted by abusive supervision by showing significantly lower levels of creativity and self-efficacy when they were subjected to high levels of abusive supervision. On the other hand, when mindfulness was high abusive supervision had no significant effect on either creativity or self-efficacy. Hence, mindfulness appeared to buffer the employees from the negative impact of abusive supervision.

 

This is a correlational study, so causation cannot be conclusively concluded. But, the relationships are clear. Mindfulness is associated with an improved ability to function effectively regardless of the supervisory methods used. This may result from the ability of mindfulness to improve the individual’s physical and psychological responses to stress. In this way, mindful individuals do not react to the stress imposed by an abusive manager and thereby their performance is unaffected. It is also possible that the ability of mindfulness to increase the individual’s ability to respond to and regulate their emotions. As a result, they are able to cope with the negative emotions produced by abusive supervision and can be productive nonetheless.

 

So, decreases the impact of abusive supervision at work with mindfulness.

 

“Blunting the harm of a workplace stressor like abusive supervision may unwittingly promote acceptance of mistreatment, potentially interfering with adaptive responses, such as proactively addressing supervisor conflicts and behavior, filing a grievance, or changing jobs. So while mindfulness may leave individuals less affected by negative work events, an open question is whether it coincides with passivity, allowing unhealthy patterns to continue unchecked.” – Darren Good

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Zheng X and Liu X (2017) The Buffering Effect of Mindfulness on Abusive Supervision and Creative Performance: A Social Cognitive Framework. Front. Psychol. 8:1588. doi: 10.3389/fpsyg.2017.01588

 

Our research draws upon social cognitive theory and incorporates a regulatory approach to investigate whyand when abusive supervision influences employee creative performance. The analyses of data from multiple time points and multiple sources reveal that abusive supervision hampers employee self-efficacy at work, which in turn impairs employee creative performance. Further, employee mindfulness buffers the negative effects of abusive supervision on employee self-efficacy at work as well as the indirect effects of abusive supervision on employee creative performance. Our findings have implications for both theory and practice. Limitations and directions for future research are also discussed.

http://journal.frontiersin.org/article/10.3389/fpsyg.2017.01588/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_398354_69_Psycho_20170921_arts_A

Meditation Can Produce Uncomfortable Effects

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Meditation Can Produce Uncomfortable Effects

 

By John M. de Castro, Ph.D.

 

“While the benefits of mediation are being recorded in scientific journals, what’s not discussed as often are the negative meditation side effects. It can be a frustrating, sometimes agonizing process that will bring you into contact with your limitations and inner conflicts. Rather than a metamorphosis, you can experience a setback.” – Linda Kaban

 

People begin meditation with the misconception that meditation will help them escape from their problems. Nothing could be further from the truth. In fact, meditation does the exact opposite, forcing the meditator to confront their issues. In meditation, the practitioner tries to quiet the mind. But, in that relaxed quiet state, powerful, highly emotionally charged thoughts and memories are likely to emerge. The strength here is that meditation is a wonderful occasion to begin to deal with these issues. But, often the thoughts or memories are overwhelming. At times, professional therapeutic intervention may be needed.

 

Meditation practice can also produce some troubling experiences beyond unmasking deep psychological issues. Not the least of these experiences are awakening experiences themselves. If they are not properly understood, they can lead to sometimes devastating consequences. These experiences are so powerful and unusual that they can be misinterpreted. Awakening experiences have been misdiagnosed as psychotic breaks and the individual placed on powerful drugs and/or institutionalized. At the very least, the individual may believe that they are losing their sanity or as one has said, “I just got used to the idea that occasionally I would have just one of those days.”

 

Meditation practice can sometimes produce energetic states that can vary in intensity, location, and duration. If and when these occur, they are usually quite surprising and unexpected. They can be readily misinterpreted. They involve energy focused in specific parts of the body or overall. They can feel like nervousness, tension, or almost like electrical currents flowing through the body and can produce spontaneous and undirected movements. These energy states are usually found to be aversive and difficult to cope with.

 

Many practitioners never experience these issues or only experience very mild states. There are, however, no systematic studies of the extent of this problem. In today’s Research News article “Unwanted effects: Is there a negative side of meditation? A multicentre survey.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584749/, Cebolla and colleagues conducted an on-line survey of meditation practitioners that engaged in a variety of different meditation techniques. They were asked if they had experienced any unwanted experiences. If they had, they were asked to describe the nature of these experiences. These incidents were categorized into 8 clusters; anxiety symptoms (including panic attacks), pain (stomach, headache, muscular, nausea), depersonalization and derealization, hypomania or depressive symptoms, emotional lability, visual focalization problems, loss of consciousness or dizziness, and other symptoms. They also completed a checklist of unwanted experiences.

 

They found that the incidence of negative events was quite high with 25.4% of the respondents reporting unwanted experiences. But most reported that the experiences were mild and transitory and most did not lead to the need for medical assistance or the cessation of meditation practice. These unwanted experiences occurred more frequently with individual rather than group practice and with focused meditation practice, particularly when practices was longer then 20 minutes. The most frequently described reactions were anxiety symptoms (including panic attacks) and depersonalization or derealization (“when I began to focus on my breath, a shift seemed to occur in my spatial awareness quite quickly. I felt like my awareness was becoming very close to me, and everything around me was becoming very distant.)

 

The results suggest that unwanted (negative) experiences are quite common with meditators, but for the most part are short-lived and mild. It should be kept in mind, however, that practitioners who had more severe and long lasting negative experience may well not continue meditation and not be included in the sample. So, the actual frequency and severity of unwanted (negative) experiences may actually be higher. There was also no comparison condition. It is possible that similar unwanted experiences occur over time in people who do not meditate.

 

The results suggest that better instruction is needed for beginning meditators regarding the types of experiences that meditators may have and resources provided for dealing with these experiences. In the West meditation has been promoted as a completely positive and beneficial practice. For the most part, it is. But, it can have significant, unpleasant, and potentially harmful consequences. It is important that practitioners be aware of this and have access to experienced teachers who can help them navigate through the difficulties if they appear.

 

It needs to be publicized that meditation can produce uncomfortable effects.

 

“To put things in perspective, many millions of people have meditated, over the past several thousands of years, and written about it extensively – there is a vast literature. If you look at this history as a vast trial run of a new drug, there are remarkably few negative side effects for such a powerful process.” – Lorin Roche

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Cebolla, A., Demarzo, M., Martins, P., Soler, J., & Garcia-Campayo, J. (2017). Unwanted effects: Is there a negative side of meditation? A multicentre survey. PLoS ONE, 12(9), e0183137. http://doi.org/10.1371/journal.pone.0183137

 

Abstract

Objectives

Despite the long-term use and evidence-based efficacy of meditation and mindfulness-based interventions, there is still a lack of data about the possible unwanted effects (UEs) of these practices. The aim of this study was to evaluate the occurrence of UEs among meditation practitioners, considering moderating factors such as the type, frequency, and lifetime duration of the meditation practices.

Methods

An online survey was developed and disseminated through several websites, such as Spanish-, English- and Portuguese-language scientific research portals related to mindfulness and meditation. After excluding people who did not answer the survey correctly or completely and those who had less than two months of meditation experience, a total of 342 people participated in the study. However, only 87 reported information about UEs.

Results

The majority of the practitioners were women from Spain who were married and had a University education level. Practices were more frequently informal, performed on a daily basis, and followed by focused attention (FA). Among the participants, 25.4% reported UEs, showing that severity varies considerably. The information requested indicated that most of the UEs were transitory and did not lead to discontinuing meditation practice or the need for medical assistance. They were more frequently reported in relation to individual practice, during focused attention meditation, and when practising for more than 20 minutes and alone. The practice of body awareness was associated with UEs to a lesser extent, whereas focused attention was associated more with UEs.

Conclusions

This is the first large-scale, multi-cultural study on the UEs of meditation. Despite its limitations, this study suggests that UEs are prevalent and transitory and should be further studied. We recommend the use of standardized questionnaires to assess the UEs of meditation practices.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584749/

Meditation Can Reduce the Age-Associated Degeneration of the Brain

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Meditation Can Reduce the Age-Associated Degeneration of the Brain

 

By John M. de Castro, Ph.D.

 

“The brain begins to decline in the 20s, and continues to decrease in volume and weight through old age. Meditation, in addition to boosting emotional and physical well-being at any time in life, may be an effective way to prevent neurodegenerative diseases like dementia, Alzheimer’s and Parkinson’s, as well as help stave off some of the normal cognitive decline that comes with aging. The strategy is free, and it comes with no side effects.” – Carolyn Gregoire

 

Human life is one of constant change. We revel in our increases in physical and mental capacities during development, but regret their decreases during aging. The aging process involves a systematic progressive decline in every system in the body, the brain included. Starting in the 20s there is a progressive decrease in the volume and activity of the brain as the years go by.

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity.  Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread area. and have found that meditation practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. In addition, they have been able to investigate various techniques that might slow the process of neurodegeneration that accompanies normal aging. They’ve found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation and yoga have been found to degenerate less with aging than non-practitioners.

 

In today’s Research News article “Reduced age-associated brain changes in expert meditators: a multimodal neuroimaging pilot study.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578985/, Chételat and colleagues recruited expert meditators with at least 10 years of experience and a total of at least 15,000 hours of meditation practice and age matched meditation naïve controls. They also included non-meditators at a wide range of ages, 20-87 years. They all underwent scanning of the brain with either Positron Emission Tomography (PET) or Magnetic Resonance Imaging (MRI). They were measured for verbal fluency, episodic memory, short-term memory, and working memory, processing speed and executive functions, frequency of participation in leisure activities before 30 and from 30 to 65 years, and the highest level of occupation reached, adherence to Mediterranean diet, sleep quality and sleep disturbance.

 

They found that the older the meditation naïve participants the lower the volume of the brain gray matter and the lower the brain metabolism. Hence, they demonstrated, as have many others, age related degeneration of the brain. On the other hand, the expert meditators had significantly greater brain gray matter volume and metabolic activity than the age matched controls in the bilateral ventromedial prefrontal and anterior cingulate cortex, insula, temporo-parietal junction, and posterior cingulate cortex /precuneus. All of the expert meditators were over 60 yet their brain volumes were in the range of meditation naïve controls in their 30s and 40s.

 

These are remarkable results that suggest that large amounts of meditation practice can help to preserve the brain countering age related decline. The amount of meditation performed by these expert meditators is so high as to be unrealistic for use with the general population. Fortunately, other research suggests that the elderly brain changes positively in response to much lower amounts of mindfulness practice. So, mindfulness training may well be a feasible practice to protect the brains of seniors from further deterioration.

 

So, use meditation to reduce the age-associated degeneration of the brain

 

“A growing body of research supports the immediate benefits of meditation, such as reduced stress and anxiety levels, lower blood pressure, and enhanced happiness. Studies on mindfulness interventions show these effects are common in as few as eight weeks. While these initial perks may be reason enough for us to practice, meditation’s positive impact appears to be even more far-reaching, potentially adding years to our lives and improving cognitive function well into old age.” – Rina Deshpande

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Chételat, G., Mézenge, F., Tomadesso, C., Landeau, B., Arenaza-Urquijo, E., Rauchs, G., … Lutz, A. (2017). Reduced age-associated brain changes in expert meditators: a multimodal neuroimaging pilot study. Scientific Reports, 7, 10160. http://doi.org/10.1038/s41598-017-07764-x

 

Abstract

Aging is associated with progressive cerebral volume and glucose metabolism decreases. Conditions such as stress and sleep difficulties exacerbate these changes and are risk factors for Alzheimer’s disease. Meditation practice, aiming towards stress reduction and emotion regulation, can downregulate these adverse factors. In this pilot study, we explored the possibility that lifelong meditation practice might reduce age-related brain changes by comparing structural MRI and FDG-PET data in 6 elderly expert meditators versus 67 elderly controls. We found increased gray matter volume and/or FDG metabolism in elderly expert meditators compared to controls in the bilateral ventromedial prefrontal and anterior cingulate cortex, insula, temporo-parietal junction, and posterior cingulate cortex /precuneus. Most of these regions were also those exhibiting the strongest effects of age when assessed in a cohort of 186 controls aged 20 to 87 years. Moreover, complementary analyses showed that these changes were still observed when adjusting for lifestyle factors or using a smaller group of controls matched for education. Pending replication in a larger cohort of elderly expert meditators and longitudinal studies, these findings suggest that meditation practice could reduce age-associated structural and functional brain changes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578985/

Improve Fibromyalgia with Tai Chi

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Improve Fibromyalgia with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Compared with patients who received wellness education and stretching exercises, those who practiced tai chi saw their fibromyalgia become much less severe. They also slept better, felt better, had less pain, had more energy, and had better physical and mental health.” – Chenchen Wang

 

Fibromyalgia is a mysterious disorder whose causes are unknown. It is very common affecting over 5 million people in the U.S., about 2% of the population with about 7 times more women affected than men. It is characterized by widespread pain, abnormal pain processing, sleep disturbance, and fatigue that lead to psychological distress. Fibromyalgia may also have morning stiffness, tingling or numbness in hands and feet, headaches, including migraines, irritable bowel syndrome, sleep disturbances, thinking and memory problems, and painful menstrual periods. The symptoms are so severe and debilitating that about half the patients are unable to perform routine daily functions and about a third have to stop work. Although it is not itself fatal, suicide rates are higher in fibromyalgia sufferers.

 

There are no completely effective treatments for fibromyalgia. Drugs and lifestyle changes are recommended but produce only limited symptomatic relief but also can produce unwanted side effects. Alternatively, mindfulness practices have been shown to be effective in reducing pain from fibromyalgia. Tai Chi is an ancient mindfulness practice involving slow prescribed movements. It is gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. In addition, Tai Chi  has been shown to reduce pain in patients with spinal cord injury. Hence, Tai Chi may be an excellent treatment for the symptoms of fibromyalgia.

 

In today’s Research News article “A randomized controlled trial of 8-form Tai chi improves symptoms and functional mobility in fibromyalgia patients.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571653/, Jones and colleagues recruited fibromyalgia sufferers and randomly assigned them to either practice Tai Chi or receive education on fibromyalgia from physicians, dieticians, and counselors for 90 minutes, twice a week, for 12 weeks. Homework and home practice was also prescribed. The participants were measured before and after the 12-week treatment period for fibromyalgia impact, including fatigue, morning tiredness, stiffness, depression, anxiety, work ability, and physical function

 

They found that the Tai Chi group in comparison to baseline and the education group had significant decreases in fibromyalgia impact, pain, sleep quality, self-efficacy, functional mobility, and balance. There were also significant reductions in pain, and improvements in sleep quality, self-efficacy, functional mobility, and balance. Importantly, none of the participants dropped out from the Tai Chi group. Hence, Tai Chi was found to be well tolerated and acceptable, and to produce clinically significant improvements in the symptoms of fibromyalgia.

 

Tai Chi can significantly improve the suffering from fibromyalgia while being acceptable for practice for patients in pain. It has no known negative side effects, is inexpensive and convenient to practice, and can be practiced alone or in groups. It appears to not only improve the psychological symptoms that can be produced by other mindfulness practices, but can also improve physical mobility including balance. Hence, Tai Chi would appear to be a nearly ideal treatment for fibromyalgia, either alone or in combination with other treatments.

 

So, improve fibromyalgia with Tai Chi.

 

“Aside from reductions in pain, patients in the tai chi group reported improvements in mood, quality of life, sleep, self-efficacy and exercise capacity. The potential efficacy and lack of adverse effects now make it reasonable for physicians to support patients’ interest in exploring these types of exercises, even if it is too early to take out a prescription pad and write ‘tai chi,’” – Gloria Yeh

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Jones, K. D., Sherman, C. A., Mist, S. D., Carson, J. W., Bennett, R. M., & Li, F. (2012). A randomized controlled trial of 8-form Tai chi improves symptoms and functional mobility in fibromyalgia patients. Clinical Rheumatology, 31(8), 1205–1214. http://doi.org/10.1007/s10067-012-1996-2

 

Abstract

Previous researchers have found that 10-form Tai chi yields symptomatic benefit in patients with fibromyalgia (FM). The purpose of this study was to further investigate earlier findings and add a focus on functional mobility. We conducted a parallel-group randomized controlled trial FM-modified 8-form Yang-style Tai chi program compared to an education control. Participants met in small groups twice weekly for 90 min over 12 weeks. The primary endpoint was symptom reduction and improvement in self-report physical function, as measured by the Fibromyalgia Impact Questionnaire (FIQ), from baseline to 12 weeks. Secondary endpoints included pain severity and interference (Brief Pain Inventory (BPI), sleep (Pittsburg sleep Inventory), self-efficacy, and functional mobility. Of the 101 randomly assigned subjects (mean age 54 years, 93 % female), those in the Tai chi condition compared with the education condition demonstrated clinically and statistically significant improvements in FIQ scores (16.5 vs. 3.1, p=0.0002), BPI pain severity (1.2 vs. 0.4, p=0.0008), BPI pain interference (2.1 vs. 0.6, p=0.0000), sleep (2.0 vs. −0.03, p=0.0003), and self-efficacy for pain control (9.2 vs. −1.5, p=0.0001). Functional mobility variables including timed get up and go (−.9 vs. −.3, p=0.0001), static balance (7.5 vs. −0.3, p= 0.0001), and dynamic balance (1.6 vs. 0.3, p=0.0001) were significantly improved with Tai chi compared with education control. No adverse events were noted. Twelve weeks of Tai chi, practice twice weekly, provided worthwhile improvement in common FM symptoms including pain and physical function including mobility. Tai chi appears to be a safe and an acceptable exercise modality that may be useful as adjunctive therapy in the management of FM patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571653/