Improve Bipolar Disorder with Few Adverse Complications with Mindfulness

April 21, 2022 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“[Mindfulness-Based Cognitive Therapy] in [bipolar disorder] is associated with improvements in cognitive functioning and emotional regulation, reduction in symptoms of anxiety depression and mania symptoms.” – Sanja Bojic

Bipolar disorder, also known as manic depressive disorder, is a mood disorder characterized by alternating states of extreme depression, relative normalcy, and extreme euphoria (mania). The symptoms of depression and mania are so severe that the individual is debilitated and unable to conduct their normal daily lives. The depression is so severe that suicide occurs in about 1% of cases of bipolar disorder. There are great individual differences in bipolar disorder. The extreme mood swings can last for a few days to months and can occur only once or reoccur frequently.

Bipolar disorder affects about 1% of the population throughout the world at any time. But about 3% to 10% of the population may experience it sometime during their lives. It is usually treated with drugs. But these medications are not always effective and can have difficult side effects. This disorder has generally been found to be very difficult to treat with psychotherapy. Hence, there is a great need for alternative treatments.

Mindfulness practices and treatments have been shown to be effective for major mental disorders, including depression and anxiety disorders and to improve the regulation of emotions. Mindfulness-Based Cognitive Therapy (MBCT) was specifically developed to treat depression. MBCT involves mindfulness training, containing sitting, walking and body scan meditations, and cognitive therapy that attempts to teach patients to distinguish between thoughts, emotions, physical sensations, and behaviors, and to recognize irrational thinking styles and how they affect behavior. But whether MBCT may produce adverse events that may worsen bipolar disorder has not been well investigated.

In today’s Research News article “Adverse or therapeutic? A mixed-methods study investigating adverse effects of Mindfulness-Based Cognitive Therapy in bipolar disorder.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568103/ ) Hanssen and colleagues recruited patients who were diagnosed with bipolar disorder and provided them with 8 weekly 2.5-hour group sessions of Mindfulness-Based Cognitive Therapy (MBCT) along with home practice. The patients completed weekly self-reports of adverse events; “any meditation related-effects that occurred during the course of MBCT, which patients indicated as having a negative valence or negative impact on daily functioning”. Patients who reported adverse events received structured interviews regarding the events.

They found that 38% of the patients reported at least one adverse event. These included in order of frequency reported self-related doubts, depression, anxiety, agitation, re-experiencing of traumatic affect, derealization, distrust, mania, depersonalization, unusual bodily sensations, and visual hallucinations. Over the course of Mindfulness-Based Cognitive Therapy (MBCT) treatment the number of patients reporting adverse events declined and the number of adverse events per patient declined. There were no serious adverse events leading to hospitalization or permanent damage. More than half of the patients found the adverse events challenging but thought that they were actually a beneficial part of their therapeutic process and the development of mindfulness skills.

This is important research as adverse events during mindfulness training even in normal individuals can produce adverse events. In seriously mentally ill individuals like those with bipolar disorder adverse event are quite common. So, understanding the nature and consequences of these events is important in calculating the risk-reward of engaging in therapy. It appears that even in these seriously mentally ill patients that the adverse events are generally mild and perceived as aiding in the therapeutic process. This suggests that the risks of therapy for these patients are small and the potential rewards great.

So, improve bipolar disorder with few adverse complications with mindfulness.

“medication can help people with bipolar disorder in the short term, and that meditation is helpful in promoting a more balanced mood over a longer period of time.” – Anthony Watt

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

Study Summary

Hanssen, I., Scheepbouwer, V., Huijbers, M., Regeer, E., Lochmann van Bennekom, M., Kupka, R., & Speckens, A. (2021). Adverse or therapeutic? A mixed-methods study investigating adverse effects of Mindfulness-Based Cognitive Therapy in bipolar disorder. PloS one, 16(11), e0259167. https://doi.org/10.1371/journal.pone.0259167

Abstract

Background

Mindfulness-Based Interventions (MBIs) are widely used in clinical and non-clinical populations, but little attention has been given to potential adverse effects (AEs).

Aims

This study aimed to gain insight in the prevalence and course of AEs during Mindfulness-Based Cognitive Therapy (MBCT) for patients with bipolar disorder (BD).

Method

The current mixed-methods study was conducted as part of a RCT on (cost-) effectiveness of MBCT in 144 patients with BD (Trial registered on 25th of April 2018, ClinicalTrials.gov, NCT03507647). During MBCT, occurrence of AEs was monitored prospectively, systematically, and actively (n = 72). Patients who reported AEs were invited for semi-structured interviews after completing MBCT (n = 29). Interviews were analysed with directed content analysis, using an existing framework by Lindahl et al.

Results

AEs were reported by 29 patients, in seven of whom the experiences could not be attributed to MBCT during the interview. AEs were reported most frequently up to week 3 and declined afterwards. Baseline anxiety appeared to be a risk factor for developing AEs. Seven existing domains of AEs were observed: cognitive, perceptual, affective, somatic, conative, sense of self, and social. Influencing factors were subdivided into predisposing, precipitating, perpetuating, and mitigating factors. With hindsight, more than half of patients considered the reported AEs as therapeutic rather than harmful.

Conclusions

Although the occurrence of AEs in MBCT for patients with BD is not rare, even in this population with severe mental illness they were not serious or had lasting bad effects. In fact, most of them were seen by the patients as being part of a therapeutic process, although some patients only experienced AEs as negative.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568103/

Improve Neuropsychological Disorders with Yoga

February 14, 2022 psyjdc Leave a comment

Improve Neuropsychological Disorders with Yoga

By John M. de Castro, Ph.D.

“yoga might be considered as an effective adjuvant for the patients with various neurological disorders including stroke, Parkinson’s disease, multiple sclerosis, epilepsy, Alzheimer’s disease, dementia, headache, myelopathy, neuropathies.” – A.Mooventhan

Mindfulness training and yoga practices have been shown to improve health and well-being in healthy individuals. They have also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. There has accumulated a large amount of research on the effectiveness of yoga practice for the treatment of a variety of physical and mental issues. Hence, it would be useful to summarize what has been learned.

In today’s Research News article “Therapeutic role of yoga in neuropsychological disorders.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546763/ ) Nourollahimoghadam and colleagues review and summarize the published research regarding the effectiveness of yoga practice for the treatment of a variety of neuropsychological disorders.

They report that the published research found that yoga practice produced significant improvements in physical illnesses including migraine headaches, Alzheimer’s Disease, epilepsy, multiple sclerosis, Parkinson’s Disease, and neuropathy. Yoga practice also produced significant improvements in psychological well-being including anxiety, stress, depression, bipolar disorder, schizophrenia, somatoform disorders, obsessive-compulsive disorder, and burnout. They further report that yoga may produce its beneficial effects by altering the chemistry, electrical activity, structures, and connectivity within the brain.

Hence Yoga practice appears to have a myriad of positive physical and psychological benefits. The authors, however, point to weaknesses in the research including small sample sizes, short-term follow-up, confounding variables, and lack of appropriate controls. So, more and better controlled studies are needed to verify the benefits of yoga practice. Hence, the present state of knowledge supports the engagement in yoga practice to advance the physical and mental well-being of both ill and healthy individuals.

So, improve neuropsychological disorders with yoga.

“Yoga can be a helpful practice of self-care for people with multiple sclerosis (MS) and other neurological conditions (such as stroke, traumatic brain injury, Parkinson’s disease, Lyme’s disease, Lou Gehrig’s disease).” – Mary Hilliker

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on on Twitter @MindfulResearch

Study Summary

Nourollahimoghadam, E., Gorji, S., Gorji, A., & Khaleghi Ghadiri, M. (2021). Therapeutic role of yoga in neuropsychological disorders. World journal of psychiatry, 11(10), 754–773. https://doi.org/10.5498/wjp.v11.i10.754

Abstract

Yoga is considered a widely-used approach for health conservation and can be adopted as a treatment modality for a plethora of medical conditions, including neurological and psychological disorders. Hence, we reviewed relevant articles entailing various neurological and psychological disorders and gathered data on how yoga exerts positive impacts on patients with a diverse range of disorders, including its modulatory effects on brain bioelectrical activities, neurotransmitters, and synaptic plasticity. The role of yoga practice as an element of the treatment of several neuropsychological diseases was evaluated based on these findings.

Core Tip: A multitude of beneficial effects of yoga practice and the underlying mechanisms of action have been reported and point out its role as an influential element in the integrative therapy of various neuropsychological disorders. In the planning of further investigations, studies should be designed to achieve more accuracy and precision in the heterogeneous field of yoga practices and potential fields of application.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546763/

Improve Anxiety Disorders in Children and Adolescents with Mindfulness

July 9, 2021 psyjdc Leave a comment

Improve Anxiety Disorders in Children and Adolescents with Mindfulness

By John M. de Castro, Ph.D.

“The more present you are in life, the more you realize you make better decisions, manage your emotions, and are fully engaged in life.” – Stephanie Gutzmer

A characterizing feature of anxiety disorders is recurring thoughts, such as impending disaster, that they may realize are unreasonable, but are unable to shake. Anxiety often co-occurs with depression or is a precursor to bipolar disorder. Anxiety disorders and depression have generally been treated with drugs. But there are considerable side effects and these drugs are often abused. In addition, drugs can be problematic for the developing brain. So, there is a need to develop alternative treatments particularly for children and adolescents. Mindfulness practices have been shown to be quite effective in relieving anxiety.

Mindfulness-Based Cognitive Therapy (MBCT) involves mindfulness training, containing sitting, walking and body scan meditations, and cognitive therapy That is designed to alter how the patient relates to the thought processes that often underlie and exacerbate psychological symptoms. MBCT has been shown to reduce anxiety. It has been proposed that intervening early may tend to mitigate or prevent future disorders So, it makes sense to examine the ability of MBCT to treat anxiety disorders in children and adolescents.

In today’s Research News article “Mindfulness-based cognitive therapy for children and adolescents with anxiety disorders at-risk for bipolar disorder: A psychoeducation waitlist controlled pilot trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307795/ ) Cotton and colleagues recruited youths aged 9-18 years diagnosed with anxiety disorder and who had at least one parent diagnosed with bipolar disorder. They were assigned in an age balanced way to either a wait-list control condition or to receive 12 weekly, 75-minute Mindfulness-Based Cognitive Therapy for Children (MBCT-C) group sessions. They were measured before and after training and weekly for anxiety, clinician-rated anxiety and anxiety-related functional impairment, emotion regulation, mindfulness, and clinician-rated illness severity.

They found that in comparison to baseline and the wait-list control group after Mindfulness-Based Cognitive Therapy for Children (MBCT-C) there was a significant reduction in clinician-rated illness severity. They also found that during the 12 weeks of treatment, the MBCT-C group had significant reductions in anxiety. In addition, the greater the increase in mindfulness the greater the reduction in anxiety and the greater the increase in emotion regulation.

These are interesting results that suggest that Mindfulness-Based Cognitive Therapy (MBCT) may be effective in reducing anxiety and illness severity in children and adolescents with anxiety disorders at-risk for bipolar disorder. In some ways these results are not surprising in that MBCT has been shown to reduce anxiety in adults and mindfulness has been found to be associated with reduced anxiety and improved emotion regulation. But MBCT might be considered as too sophisticated for children and adolescents. So, it is significant that it can be successfully applied to children and adolescents. It can relieve their anxiety and decrease the intensity of their disorder.

So, improve anxiety disorders in children and adolescents with mindfulness.

“Being mindful means paying attention to the present moment, exactly as it is. It is really hard to be anxious if you are completely focused on the present moment – what you are sensing and doing RIGHT NOW … and NOW … and NOW.” – Anxiety Canada

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Cotton, S., Kraemer, K. M., Sears, R. W., Strawn, J. R., Wasson, R. S., McCune, N., Welge, J., Blom, T. J., Durling, M., & Delbello, M. P. (2020). Mindfulness-based cognitive therapy for children and adolescents with anxiety disorders at-risk for bipolar disorder: A psychoeducation waitlist controlled pilot trial. Early intervention in psychiatry, 14(2), 211–219. https://doi.org/10.1111/eip.12848

Abstract

Aim.

Previous studies suggest that Mindfulness-Based Cognitive Therapy for Children (MBCT-C) is feasible and may improve anxiety and emotion regulation in youth with anxiety disorders at-risk for bipolar disorder. However, controlled studies are warranted to replicate and extend these findings.

Methods.

In the current study, 24 youth with anxiety disorders who have at least one parent with bipolar disorder participated in a MBCT-C treatment period (n = 24; Mage = 13.6, 75% girls, 79% White) with a subset also participating in a prior psychoeducation waitlist control period (n = 19 Mage = 13.8, 68% girls, 84% White). Participants in both the waitlist and MBCT-C periods completed independently-rated symptom scales at each time point. Participants in the waitlist period received educational materials 12 weeks prior to the beginning of MBCT-C.

Results.

There were significantly greater improvements in overall clinical severity in the MBCT-C period compared to the waitlist period, but not in clinician- and child-rated anxiety, emotion regulation or mindfulness. However, increases in mindfulness were associated with improvements in anxiety and emotion regulation in the MBCT-C period, but not the waitlist period.

Conclusions.

Findings suggest that MBCT-C may be effective for improving overall clinical severity in youth with anxiety disorders who are at-risk for bipolar disorder. However, waitlist controlled designs may inflate effect sizes so interpret with caution. Larger studies utilizing prospective randomized controlled designs are warranted.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307795/

Improve Bipolar Disorder with Mindfulness-Based Cognitive Therapy

November 13, 2020 psyjdc Leave a comment

Improve Bipolar Disorder with Mindfulness-Based Cognitive Therapy

By John M. de Castro, Ph.D.

“Bipolar disorder can be complicated by stress, and having bipolar disorder is stressful in itself. Relaxation techniques such as meditation can reduce the stress you experience from bipolar disorder, which can help you keep your mood in check.” – Timothy Legg

Bipolar Disorder, also known as Manic Depressive Disorder, is a mood disorder characterized by alternating states of extreme depression, relative normalcy, and extreme euphoria (mania). The symptoms of depression and mania are so severe that the individual is debilitated and unable to conduct their normal daily lives. The depression is so severe that suicide occurs in about 1% of cases of Bipolar Disorder. There are great individual differences in Bipolar Disorder. The extreme mood swings can last for a few days to months and can occur only once or reoccur frequently.

It would seem appropriate to summarize what has been learned about the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) for the treatment of bipolar disorder. In today’s Research News article “Mindfulness-based cognitive therapy for bipolar disorder: A systematic review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448295/) Lovas and colleagues review and summarize the published research studies of the effectiveness of MBCT for the treatment of bipolar disorder. They identified 13 published research studies.

They report that the published research studies found that Mindfulness-Based Cognitive Therapy (MBCT) significantly reduced depressive symptoms of patients with bipolar disorder while not eliciting symptoms of mania. MBCT appears to also reduce anxiety and suicidality. It appears to reduce depressive symptoms and improve mood by decreasing rumination, repetitive negative thoughts. It also appeared to improve attentional control, broadening present moment awareness from a focus on negative thoughts. In addition, it appears to create reappraisal, such that the patients were able to reappraise their negative thoughts as just thoughts and not facts. The improvements in depressive symptoms were found to be related to the amount of home practice during MBCT training.

These are promising results suggesting that Mindfulness-Based Cognitive Therapy (MBCT) is a safe and effective treatment for the depressive symptoms of bipolar disorder. But the authors report that the published research studies were generally of low research quality and underpowered to discern statistically significant effects. So, better designed and larger studies need to be conducted before firm conclusions regarding benefits can be reached.

So, improve bipolar disorder with Mindfulness-Based Cognitive Therapy.

“mindfulness-based cognitive therapy (MBCT) may help individuals with bipolar disorder prevent depressive episodes and has lasting benefits to the brain and cognition.” – BP Magazine

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Lovas, D. A., & Schuman-Olivier, Z. (2018). Mindfulness-based cognitive therapy for bipolar disorder: A systematic review. Journal of affective disorders, 240, 247–261. https://doi.org/10.1016/j.jad.2018.06.017

Abstract

Background:

Persisting high levels of relapse, morbidity and mortality in bipolar disorder (BD) in spite of first-line, evidence-based psychopharmacology has spurred development and research on adjunctive psychotherapies. Mindfulness-based cognitive therapy (MBCT) is an emerging psychotherapy that has shown benefit in related and comorbid conditions such as major depressive, anxiety, and substance disorders. Furthermore, neurocognitive studies of MBCT suggest that that may have effects on some of the theorized pathophysiological processes in BD.

Methods:

We conducted a systematic literature review using PsychINFO and PubMed databases to identify studies reporting clinical and/or neurocognitive findings for MBCT for BD.

Results:

This search revealed 13 articles. There was a wide range in methodological quality and most studies were underpowered or did not present power calculations. However, MBCT did not appear to precipitate mania, and there is preliminary evidence to support a positive effect on anxiety, residual depression, mood regulation, and broad attentional and frontal-executive control.

Limitations:

As meta-analysis is not yet possible due to study heterogeneity and quality, the current review is a narrative synthesis, and therefore net effects cannot be estimated.

Conclusions:

MBCT for BD holds promise, but more high-quality studies are needed in order to ascertain its clinical efficacy. Recommendations to address the limitations of the current research are made.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448295/

Improve Bipolar Disorder with a Mindfulness-Based Therapy (Dialectical Behavioral Therapy, DBT)

January 7, 2020 psyjdc Leave a comment

Improve Bipolar Disorder with a Mindfulness-Based Therapy (Dialectical Behavioral Therapy, DBT)

By John M. de Castro, Ph.D.

“The skills training and treatment model of DBT is applicable to people living with a range of mental health conditions. Practicing mindfulness helps people with and without mental health conditions to improve well-being, attention to the present moment, and increasing positive emotional experiences while decreasing negative emotions and distress. This is why people with depression, bipolar, anxiety, eating disorders, and other mental health conditions may benefit from mindfulness practice and the other skills that form dialectical behavior therapy.” – Jeremy Schwartz

Bipolar Disorder affects about 1% of the population throughout the world at any time. But about 3% to 10% of the population may experience it sometime during their lives. It is usually treated with drugs. But these medications are not always effective and can have difficult side effects. Hence, there is a great need for alternative treatments. Mindfulness practices and treatments have been shown to be effective for major mental disorders, including depression and anxiety disorders and to improve the regulation of emotions.

Dialectical Behavior Therapy (DBT) is a mindfulness-based therapy targeted at changing the problem behaviors. Behavior change is accomplished through focusing on changing the thoughts and emotions that precede problem behaviors, as well as by solving the problems faced by individuals that contribute to problematic thoughts, feelings and behaviors. In DBT five core skills are practiced; mindfulness, distress tolerance, emotion regulation, the middle path, and interpersonal effectiveness. So, it makes sense to further study the ability of DBT to treat the symptoms of Bipolar Disorder.

In today’s Research News article “Effectiveness of Dialectical Behavioral Therapy on Executive Function, Emotional Control and Severity of Symptoms in Patients with Bipolar I Disorder.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796294/), Zagar and colleagues recruited patients with Bipolar Disorder Type 1, aged 20-45 years, and were randomly assigned to receive either Dialectical Behavior Therapy (DBT) or no additional treatment. All participants maintained their prescribed drug regimen. DBT was delivered in 12 weekly, 1.5 hour sessions. They were measured before and after treatment and 3 months later for mania, depression, emotional control, and cognitive executive function.

They found that the group receiving Dialectical Behavior Therapy (DBT) had significant reductions in mania and depressed mood following the treatment. These results suggest that DBT is a safe and effective treatment for Bipolar Disorder when provided in addition to drug therapy. No 3-month follow-up measures were reported. Hence, it is not known whether these improvements are lasting. Further research is warranted.

So, improve Bipolar Disorder with a mindfulness-based therapy (Dialectical Behavioral Therapy, DBT).

“DBT helps people learn and implement four skills to create what they determine to be a life worth living: mindfulness, the ability to tolerate distress, the ability to regulate emotions, and healthy communication skills.” – Robin Flanigan

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Zargar, F., Haghshenas, N., Rajabi, F., & Tarrahi, M. J. (2019). Effectiveness of Dialectical Behavioral Therapy on Executive Function, Emotional Control and Severity of Symptoms in Patients with Bipolar I Disorder. Advanced biomedical research, 8, 59. doi:10.4103/abr.abr_42_19

Abstract

Background:

Bipolar disorder is a disabling illness characterized by recurrent episodes of mania, hypomania, and depression. The dialectical behaviour therapy (DBT) is basically designed to help regulate excitement, tolerance of discomfort, mindfulness and interpersonal relationships. This study aimed to determine the effectiveness of DBT on executive function, emotional control and symptom relief in patients with type 1 bipolar disorder.

Materials and Methods:

This clinical trial was conducted on 50 patients with type 1 bipolar disorder. These patients were divided into two 25 populated groups of controls and intervention. The control group did not receive any other alternative therapy apart from routine medications, but in the intervention group, in addition to routine medications, DBT treatment was also done as complementary therapy in 12 sessions based on Dick’s protocol. Then, Mania severity, emotional control and their executive functions were evaluated before and after the intervention and compared in two groups.

Results:

After the intervention, the scores of mania and depression mood with the mean of 2.12 ± 3.09 and 31.08 ± 8.98 respectively in intervention group were significantly lower than control group with the mean of 4.24 ± 4.11 and 39.92 ± 9.05 respectively (P < 0.05). Depression and executive function of the patients had no significant difference between the two groups in the post-intervention period and had a modest and non-significant change.

Conclusion:

DBT has been effective in decreasing the intensity of mania, but, it cannot be used to reduce the emotional instability and impulsivity of these patients along with drug therapy although it has improved the executive functions and depression of the patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796294/

Improve Psychopathology with Meditation

August 26, 2019 psyjdc Leave a comment

Improve Psychopathology with Meditation

By John M. de Castro, Ph.D.

“The research is strong for mindfulness’ positive impact in certain areas of mental health, including stress reduction, emotion and attention regulation, reduced rumination, for reducing mild to moderate depression and anxiety, and preventing depressive relapse.” – Kelle Walsh

There are vast numbers of people who suffer with mental illnesses; psychopathology. In the United states it has been estimated that in any given year 1 in 5 people will experience a mental illness. Many are treated with drugs. But drug treatment can produce unwanted side effects, don’t work for many patients, and often can lose effectiveness over time. Mindfulness practices provide a safe alternative treatment. They have been found to be helpful with coping with these illnesses and in many cases reducing the symptoms of the diseases. Hence, it appears that mindfulness practices are safe and effective treatments for a variety of psychiatric conditions including anxiety, depression, psychoses, addictions, etc.. Since there has accumulated a large amount of research, it makes sense to step back and summarize what has been discovered.

In today’s Research News article “Mindfulness Meditation and Psychopathology.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597263/), Wielgosz and colleagues review and summarize the published research studies investigating the efficacy of mindfulness meditation practices for the treatment of a variety of psychopathologies.

They report that mindfulness meditation produces significant improvements in depression and in anxiety disorders in comparison to inactive and active control conditions. Efficacy is equivalent to that of other evidence-based treatments. The research suggests that meditation reduces depression by decreasing rumination and anxiety by reducing repetitive negative thinking. Hence, meditation training is an excellent safe and effective treatment for these prevalent mental illnesses.

They also report that mindfulness meditation produces significant improvements in chronic pain intensity and unpleasantness in comparison to inactive but not active control conditions. Efficacy is equivalent to that of other evidence-based treatments. This is true for chronic low back pain fibromyalgia, migraine, and chronic pelvic pain. Meditation also appears to improve the quality of life of chronic pain patients. The research suggests that meditation reduces chronic pain by decreasing negative emotional reactivity. Such reactivity appears to intensify pain and meditation reduces this reactivity and thereby reduces pain.

They report that mindfulness meditation produces significant improvements in substance abuse disorders in comparison to inactive and active control conditions and even in comparison to other evidence-based treatments. It appears to reduce substance use frequency, use-related problems, and craving. This is important as addictions are very difficult to treat and frequently relapse.

There is evidence that mindfulness meditation is effective in the treatment of attention deficit hyperactivity disorder (ADHD) both in children and adults and also post-traumatic stress disorder (PTSD). But there are currently no comparisons to the effects of other active or evidence-based treatments. It will be important to have randomized controlled trials with active controls to better assess the efficacy of meditation for the treatment of ADHD and PTSD.

There is emerging evidence that mindfulness meditation may be effective for eating disorders, and major mental illnesses such as bipolar disorder, major depression, and psychosis. But there is a need for more, better controlled research.

Hence, this comprehensive review suggests that mindfulness meditation is a useful treatment for a variety of types of psychopathology. It is amazing that such a simple practice as meditation can have such wide-ranging benefits for such diverse mental illnesses. Meditation appears to act indirectly by strengthening cognitive, emotional, and stress related process that in turn have beneficial effects on the psychopathologies. Hence, it is clear that mindfulness meditation is a safe and effective treatment for psychopathologies that can be used alone or in combination with other treatments.

So, improve psychopathology with meditation.

“When they’re depressed, people are locked in the past. They’re ruminating about something that happened that they can’t let go of. When they’re anxious, they’re ruminating about the future — it’s that anticipation of what they can’t control. In contrast, when we are mindful, we are focused on the here and now. Mindfulness trains individuals to turn their attention to what is happening in the present moment.” – Carolyn Gregoire

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Wielgosz, J., Goldberg, S. B., Kral, T., Dunne, J. D., & Davidson, R. J. (2019). Mindfulness Meditation and Psychopathology. Annual review of clinical psychology, 15, 285–316. doi:10.1146/annurev-clinpsy-021815-093423

Abstract

Mindfulness meditation is increasingly incorporated into mental health interventions, and theoretical concepts associated with it have influenced basic research on psychopathology. Here, we review the current understanding of mindfulness meditation through the lens of clinical neuroscience, outlining the core capacities targeted by mindfulness meditation and mapping them onto cognitive and affective constructs of the Research Domain Criteria matrix proposed by the National Institute of Mental Health. We review efficacious applications of mindfulness meditation to specific domains of psychopathology including depression, anxiety, chronic pain, and substance abuse, as well as emerging efforts related to attention disorders, traumatic stress, dysregulated eating, and serious mental illness. Priorities for future research include pinpointing mechanisms, refining methodology, and improving implementation. Mindfulness meditation is a promising basis for interventions, with particular potential relevance to psychiatric comorbidity. The successes and challenges of mindfulness meditation research are instructive for broader interactions between contemplative traditions and clinical psychological science.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597263/

Improve Major Mental Illnesses with Mindfulness and Yoga

June 17, 2019 psyjdc Leave a comment

Improve Major Mental Illnesses with Mindfulness and Yoga

By John M. de Castro, Ph.D.

“for many patients dealing with depression, anxiety, or stress, yoga may be a very appealing way to better manage symptoms. Indeed, the scientific study of yoga demonstrates that mental and physical health are not just closely allied, but are essentially equivalent. The evidence is growing that yoga practice is a relatively low-risk, high-yield approach to improving overall health.” – Harvard Health

There are vast numbers of people who suffer with mental illnesses. In the United states it has been estimated that in any given year 1 in 5 people will experience a mental illness. Many are treated with drugs. But drug treatment can produce unwanted side effects, don’t work for many patients, and often can lose effectiveness over time. Mindfulness practices provide a safe alternative treatment. They have been found to be helpful with coping with these illnesses and in many cases reducing the symptoms of the diseases. Hence, it appears that mindfulness practices are safe and effective treatments for a variety of psychiatric conditions including anxiety, depression, psychoses, addictions, etc..

Yoga practice is a mindfulness practice that includes beneficial exercise. There is accumulating research that mindfulness and yoga practices may be beneficial for patients with major mental illnesses. Hence it makes sense to step back and summarize what has been learned regarding the effectiveness of yoga practice for major mental illnesses.

In today’s Research News article “Role of Yoga and Mindfulness in Severe Mental Illnesses: A Narrative Review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329226/), Sathyanarayanan and colleagues reviewed and summarized published research studies of the effects of mindfulness and yoga practices for the treatment of major mental illnesses including schizophrenia, psychosis, major depression, and bipolar disorder. They identified 49 published studies.

They report that the research finds that yoga practice is effective in improving the symptoms of schizophrenia including reducing emotional and social withdrawal, and improving flat emotions, rapport, spontaneity, and cognitive functions, including attention and cognitive flexibility. There were also significant improvements in social and occupational functioning, quality of life, achieving functional remission, subjective well-being, personal hygiene, life skills, interpersonal activities, and communication. Mindfulness-Based treatments were also effective in improving the symptoms of schizophrenia including stress, anxiety, depression, obsession, anger, impulsivity, lack of concentration, agoraphobic symptoms, awareness of the psychotic experiences and helps individuals to articulate their distress.

Yoga and mindfulness practices have been shown to significantly improve bipolar disorder including improvements in cognitive, emotional, and physical domains. Yoga and mindfulness practices have also been shown to improve the symptoms of major depressive disorder, including significant reductions in depression and anxiety and increases in activation. They have also been shown to reduce depression in Post-Traumatic Stress Disorder (PTSD).

In most of the reviewed studies the patients continued drug treatments and yoga and mindfulness trainings were provided in addition to the drug treatments. This suggests that both yoga and mindfulness practices are safe and effective adjunctive treatment for major mental illnesses. This is particularly significant as these illnesses are particularly difficult to treat. Hence, the additional benefits of yoga and mindfulness practices are very important and welcome in the treatment of these debilitating conditions.

So, improve major mental illnesses with mindfulness and yoga.

“Yoga is incredible in terms of stress management. It brings a person back to homeostasis [or equilibrium]. For people who have anxieties of many kinds, yoga helps lower their basic physiological arousal level.” – Eleanor Criswell

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Sathyanarayanan, G., Vengadavaradan, A., & Bharadwaj, B. (2019). Role of Yoga and Mindfulness in Severe Mental Illnesses: A Narrative Review. International journal of yoga, 12(1), 3–28. doi:10.4103/ijoy.IJOY_65_17

Abstract

Background:

Yoga has its origin from the ancient times. It is an integration of mind, body, and soul. Besides, mindfulness emphasizes focused awareness and accepting the internal experiences without being judgemental. These techniques offer a trending new dimension of treatment in various psychiatric disorders.

Aims:

We aimed to review the studies on the efficacy of yoga and mindfulness as a treatment modality in severe mental illnesses (SMIs). SMI includes schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD).

Methods:

We conducted a literature search using PubMed, Google Scholar, and Cochrane Library with the search terms “yoga,” “meditation,” “breathing exercises,” “mindfulness,” “schizophrenia spectrum and other psychotic disorders,” “depressive disorder,” and “bipolar disorder” for the last 10-year period. We also included relevant articles from the cross-references.

Results:

We found that asanas and pranayama are the most commonly studied forms of yoga for schizophrenia. These studies found a reduction in general psychopathology ratings and an improvement in cognition and functioning. Some studies also found modest benefits in negative and positive symptoms. Mindfulness has not been extensively tried, but the available evidence has shown benefits in improving psychotic symptoms, improving level of functioning, and affect regulation. In MDD, both yoga and mindfulness have demonstrated significant benefit in reducing the severity of depressive symptoms. There is very sparse data with respect to BD.

Conclusion:

Both yoga and mindfulness interventions appear to be useful as an adjunct in the treatment of SMI. Studies have shown improvement in the psychopathology, anxiety, cognition, and functioning of patients with schizophrenia. Similarly, both the techniques have been established as an effective adjuvant in MDD. However, more rigorously designed and larger trials may be necessary, specifically for BD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329226/

Improve Severe Mental Illness with Yoga and Mindfulness

March 25, 2019 psyjdc Leave a comment

Improve Severe Mental Illness with Yoga and Mindfulness

By John M. de Castro, Ph.D.

“yoga does in fact have positive effects on mild depression and sleep problems, and it improves the symptoms of psychiatric disorders like schizophrenia and ADHD among patients using medication.” – Alexandra Sifferin

Psychoses are mental health problems that cause people to perceive or interpret things differently from those around them. This might involve hallucinations; seeing and, in some cases, feeling, smelling or tasting things that aren’t objectively there, or delusions; unshakable beliefs that, when examined rationally, are obviously untrue. The combination of hallucinations and delusional thinking can often severely disrupt perception, thinking, emotion, and behavior, making it difficult if not impossible to function in society without treatment. Psychoses appear to be highly heritable and involves changes in the brain. Psychoses are very difficult to treat with psychotherapy and are usually treated with antipsychotic drugs. These drugs, however, are not always effective, sometimes lose effectiveness, and can have some difficult side effects. Hence, there is a need for safe and effective alternative treatments for psychosis.

Clinically diagnosed depression is the most common mental illness, affecting over 6% of the population. Major depression can be quite debilitating. It is also generally episodic, coming and going. Some people only have a single episode but most have multiple reoccurrences of depression. Depression can be difficult to treat. It is usually treated with antidepressant medication. But, of patients treated initially with drugs only about a third attained remission of the depression. After repeated and varied treatments including drugs, therapy, exercise etc. only about two thirds of patients attained remission. But drugs often have troubling side effects and can lose effectiveness over time.

Clearly, there is a need for treatment alternatives that can be effective alone or in combination with drugs. Both mindfulness and yoga training has been shown to be beneficial for patients with psychosis and with major depression. It is important at this point to step back and review the published studies of the application of mindfulness and yoga practices for the treatment of severe mental illnesses, In today’s Research News article “Role of Yoga and Mindfulness in Severe Mental Illnesses: A Narrative Review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329226/ ), Sathyanarayanan and colleagues review and summarize 49 published research studies on the effectiveness of mindfulness and yoga practices for the treatment of severe mental illnesses.

They report that the research finds that both mindfulness practices and yoga practice in combination with antipsychotic medications significantly reduces both the positive and negative symptoms of schizophrenia and other psychotic disorders, improves the patient’s ability to effectively engage in everyday activities and also improves higher level thought processes, cognition. With Bipolar Disorder they report that there are only a very small number of studies that suggest improvements but more research is needed. With Major Depressive Disorders both mindfulness and yoga practices have been shown to produce significant reductions in depression alone or in combination with anti-depressive medications.

Hence, they find that the current published research supports the use of either mindfulness or yoga practices for the treatment of severe mental illnesses. There is clearly a need for more research, but the studies to date are very encouraging. They suggest that these practices are safe and effective whether used alone or in combination with drugs and may then be a needed alternative treatment to drugs.

So, improve severe mental illness with yoga and mindfulness.

“Yoga can be an incredible tool for self-growth, empowerment, healing, and health for those with mental disorders.” – Zoie Kanakis

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Sathyanarayanan, G., Vengadavaradan, A., & Bharadwaj, B. (2019). Role of Yoga and Mindfulness in Severe Mental Illnesses: A Narrative Review. International journal of yoga, 12(1), 3-28.

Abstract

Background:

Aims:

Methods:

Results:

Conclusion:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329226/

Improve Bipolar Disorders in Low and Middle Income Countries with Mindfulness

February 18, 2019 psyjdc Leave a comment

Improve Bipolar Disorders in Low and Middle Income Countries with Mindfulness

By John M. de Castro, Ph.D.

“Mindfulness-based cognitive therapy appears to have lasting benefits for people with bipolar disorder, , , incorporating mindfulness practices and mindful breathing into daily life on a regular basis was associated with better prevention of depressive relapse.” – Mahesh Agrawal

There are a number of alternative treatments including mindfulness that have been shown to be effective for bipolar disorder in developed affluent countries. But bipolar disorder knows no borders. Countries with less affluent citizens are just as likely to suffer from bipolar disorder but may react differently to these treatments. Hence, there is a need to assesses the effectiveness of these alternative treatments on bipolar disorder in middle and low income countries.

In today’s Research News article “Psychological interventions for bipolar disorder in low- and middle-income countries: systematic review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127962/ ), Demissie and colleagues review and summarize the published research literature on the effectiveness of alternative treatments for bipolar disorder in countries with middle to low general income levels. They examined randomized controlled research studies that employed “any psychological intervention delivered either face to face (individual or group format) or online.” These included psychoeducation, family therapy, Cognitive Behavioral Therapy (CBT), or Mindfulness-Based Cognitive Therapy (MBCT).

They identified 18 studies 15 of which included psychoeducation, 2 CBT and 1 MBCT. They report that psychoeducation was effective in preventing relapse and improving treatment adherence while CBT was effective in prolonging the period of remission. All three intervention types were effective in reducing psychiatric symptoms and MBCT was also effective in promoting emotion regulation and mindfulness.

These studies suggest that alternative treatments are effective in treating bipolar disorder in middle and low income countries as they are in affluent countries. Psychoeducation appears well studied and effective. There were, however, only 2 studies with CBT and only 1 with MBCT. They suggest efficacy. But much more research is needed particularly comparing the different adjunctive treatments to determine which produce the greatest improvements alone or in combination with drugs.

So, improve bipolar disorders in low and middle income countries with psychoeducation, cognitive therapy, or mindfulness.

“Even though it’s not a cure for bipolar disorder, meditation can help you relax and reduce stress. It can also help you disengage from stressful or anxious thoughts, and better control your mood.” – Anthony Watt

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Demissie, M., Hanlon, C., Birhane, R., Ng, L., Medhin, G., & Fekadu, A. (2018). Psychological interventions for bipolar disorder in low- and middle-income countries: systematic review. BJPsych open, 4(5), 375-384. doi:10.1192/bjo.2018.46

Abstract

Background

Adjunctive psychological interventions for bipolar disorder have demonstrated better efficacy in preventing or delaying relapse and improving outcomes compared with pharmacotherapy alone.

Aims

To evaluate the efficacy of psychological interventions for bipolar disorder in low- and middle-income countries.

Method

A systematic review was conducted using PubMed, PsycINFO, Medline, EMBASE, Cochrane database for systematic review, Cochrane central register of controlled trials, Latin America and Caribbean Center on Health Science Literature and African Journals Online databases with no restriction of language or year of publication. Methodological heterogeneity of studies precluded meta-analysis.

Results

A total of 18 adjunctive studies were identified: psychoeducation (n = 14), family intervention (n = 1), group cognitive–behavioural therapy (CBT) (n = 2) and group mindfulness-based cognitive therapy (MBCT) (n = 1). In total, 16 of the 18 studies were from upper-middle-income countries and none from low-income countries. All used mental health specialists or experienced therapists to deliver the intervention. Most of the studies have moderately high risk of bias. Psychoeducation improved treatment adherence, knowledge of and attitudes towards bipolar disorder and quality of life, and led to decreased relapse rates and hospital admissions. Family psychoeducation prevented relapse, decreased hospital admissions and improved medication adherence. CBT reduced both depressive and manic symptoms. MBCT reduced emotional dysregulation.

Conclusions

Adjunctive psychological interventions alongside pharmacotherapy appear to improve the clinical outcome and quality of life of people with bipolar disorder in middle-income countries. Further studies are required to investigate contextual adaptation and the role of non-specialists in the provision of psychological interventions to ensure scalability and the efficacy of these interventions in low-income country settings.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127962/

Improve Mental Health with Mindfulness

May 31, 2018 psyjdc Leave a comment

Improve Mental Health with Mindfulness

By John M. de Castro, Ph.D.

“While mindfulness will not solve all of our problems, it is a powerful tool with great potential to help us all transform our relationship with our problems when it is not possible, or desirable, to eliminate them.” – Elana Miller

Mindfulness training has been shown to be effective in improving physical and psychological health and particularly with the physical and psychological reactions to stress. Techniques such as Mindfulness Training, Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT) as well as Yoga practice and Tai Chi or Qigong practice have been demonstrated to be effective. This has led to an increasing adoption of these mindfulness techniques for the physical and psychological health and well-being of both healthy and ill individuals.

In today’s Research News article “Mindfulness-Based Interventions in Psychiatry.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870875/ ), Shapero and colleagues review and summarize the published research literature on the application of mindfulness techniques to the treatment of mental illnesses.

They report that the most commonly used mindfulness technique for the treatment of mental illness is Mindfulness-Based Cognitive Therapy (MBCT) particularly for the treatment of major depressive disorder. MBCT has been shown to be as effective as antidepressant drugs in relieving the symptoms of depression and preventing depression reoccurrence and relapse. In addition, it appears to be effective as either a supplement to or a replacement for these drugs.

Mindfulness-based interventions (MBIs) have also been found to improve mood and relieve anxiety in patients suffering from anxiety and mood disorders and treat the symptoms of Bipolar Disorder, Obsessive Compulsive Disorder, Generalized Anxiety Disorder, and eating disorders. They have also been found to reduce drug cravings and use as well as reduce substance abuse relapse after treatment.

They further report that the research suggests that Mindfulness-based interventions (MBIs) produce these benefits by focusing on the present moment in a non-reactive and non-judgmental way and improving emotion regulation and thereby decreasing negative thought patterns, emotional reactivity, rumination, and worry, and increasing self-compassion. In the cognitive realm, MBIs appear to produce a different relationship with the thoughts of the individuals by noticing them and developing different ways of relating and reacting to them.

One way that MBIs appear to have their effects is by altering the nervous system in a process known as neuroplasticity. These include changes to eight brain regions, including areas associated with meta-awareness (frontopolar cortex), exteroceptive and interoceptive body awareness (sensory cortices and insula), memory consolidation and reconsolidation (hippocampus), self and emotion regulation (anterior and mid cingulate; orbitofrontal cortex), and intra- and interhemispheric communication (superior longitudinal fasciculus; corpus callosum).

These are striking findings that strongly suggest that Mindfulness-based interventions (MBIs) are safe and very effective treatments for a wide array of psychiatric disorders. They appear to work by altering thought processes, emotion regulation, and focus on the present moment. They appear to alter the brain to produce these benefits. This suggests that MBIs should be widely prescribed to relieve the symptoms and suffering produced by mental illness.

So, improve mental health with Mindfulness.

“Mindfulness and the traditional way psychiatry is practiced are really more divergent than anything else. Psychiatry is about removing emotional pain, whereas mindfulness teaches us the value of being present with our pain. It was through the practice of mindfulness that I started to learn this new perspective and started to relate to my own pain differently. Instead of running away from it, I was taught to welcome it; to befriend it and thus convert it into a source for my own emotional and spiritual growth.” – Russel Razzaque

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Shapero, B. G., Greenberg, J., Pedrelli, P., de Jong, M., & Desbordes, G. (2018). Mindfulness-Based Interventions in Psychiatry. Focus (American Psychiatric Publishing), 16(1), 32–39. http://doi.org/10.1176/appi.focus.20170039

Abstract

Mindfulness meditation has a longstanding history in eastern practices that has received considerable public interest in recent decades. Indeed, the science, practice, and implementation of Mindfulness Based Interventions (MBIs) have dramatically increased in recent years. At its base, mindfulness is a natural human state in which an individual experiences and attends to the present moment. Interventions have been developed to train individuals how to incorporate this practice into daily life. The current article will discuss the concept of mindfulness and describe its implementation in the treatment of psychiatric disorders. We further identify for whom MBIs have been shown to be efficacious and provide an up-to-date summary of how these interventions work. This includes research support for the cognitive, psychological, and neural mechanisms that lead to psychiatric improvements. This review provides a basis for incorporating these interventions into treatment.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870875/