Aging

Alter the Genes for Better Health with Meditation

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Alter the Genes for Better Health with Meditation

 

By John M. de Castro, Ph.D.

 

“meditation practices seem . . . promote endocrinal, neuronal, and behavioral functions. This suggests that the achievement of a state of inner silence through the practice of meditation can prevent or reverse the detrimental effects of a stressful environment.“ – Sabrina Venditti

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

 

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. Hence, it is important to study the epigenetic alterations in gene expressions produced by meditation practice to determine if these effects are the intermediary between meditation and health.

 

In today’s Research News article “Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/ ) Wenuganen and colleagues recruited older (> 60 years of age) healthy adult experienced practitioners of Transcendental Meditation and matched non-practitioners. Blood was drawn and analyzed for gene expression with microarrays and polymerase chain reaction.

 

They found that the genes of the Transcendental Meditation practitioners were in general significantly downregulated (lower expression) than the non-practitioners. “Sixty-two genes were related to hematologic diseases, 26 to coronary artery disease, 34 to diabetes complications, 49 to inflammation, and 64 to CVD. All these disease-related genes were downregulated in the TM group relative to the control group.” The genes found to have lower expression in the Transcendental Meditation practitioners were related to inflammatory responses and suppressed energy efficiency, while those upregulated (higher expression) were related to immune system function.

 

These epigenetic findings suggest that Transcendental Meditation practice over years of practice improve the immune system and energy efficiency while reducing inflammation in older individuals. These epigenetic changes suggest that Transcendental Meditation practice improves the physiology’s ability to maintain health by being better prepared to respond to disease and stress. This suggests a mechanism by which meditation practice improves health and longevity.

 

So, alter the genes for better health with meditation.

 

“meditation, yoga, and Tai Chi . . . all seem to have a beneficial effect on the expression of a slew of different genes. And, as you might expect, the affected genes are generally those involved in stress and inflammation.” – Alice Walton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are a

Alter the Genes for Better Health with Meditation

 

By John M. de Castro, Ph.D.

 

“meditation practices seem . . . promote endocrinal, neuronal, and behavioral functions. This suggests that the achievement of a state of inner silence through the practice of meditation can prevent or reverse the detrimental effects of a stressful environment.“ – Sabrina Venditti

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

 

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. Hence, it is important to study the epigenetic alterations in gene expressions produced by meditation practice to determine if these effects are the intermediary between meditation and health.

 

In today’s Research News article “Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/ ) Wenuganen and colleagues recruited older (> 60 years of age) healthy adult experienced practitioners of Transcendental Meditation and matched non-practitioners. Blood was drawn and analyzed for gene expression with microarrays and polymerase chain reaction.

 

They found that the genes of the Transcendental Meditation practitioners were in general significantly downregulated (lower expression) than the non-practitioners. “Sixty-two genes were related to hematologic diseases, 26 to coronary artery disease, 34 to diabetes complications, 49 to inflammation, and 64 to CVD. All these disease-related genes were downregulated in the TM group relative to the control group.” The genes found to have lower expression in the Transcendental Meditation practitioners were related to inflammatory responses and suppressed energy efficiency, while those upregulated (higher expression) were related to immune system function.

 

These epigenetic findings suggest that Transcendental Meditation practice over years of practice improve the immune system and energy efficiency while reducing inflammation in older individuals. These epigenetic changes suggest that Transcendental Meditation practice improves the physiology’s ability to maintain health by being better prepared to respond to disease and stress. This suggests a mechanism by which meditation practice improves health and longevity.

 

So, alter the genes for better health with meditation.

 

“meditation, yoga, and Tai Chi . . . all seem to have a beneficial effect on the expression of a slew of different genes. And, as you might expect, the affected genes are generally those involved in stress and inflammation.” – Alice Walton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available at the Contemplative Studies Blog http://contemplative-studies.org/wp/

They are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wenuganen, S., Walton, K. G., Katta, S., Dalgard, C. L., Sukumar, G., Starr, J., Travis, F. T., Wallace, R. K., Morehead, P., Lonsdorf, N. K., Srivastava, M., & Fagan, J. (2021). Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health. Medicina (Kaunas, Lithuania), 57(3), 218. https://doi.org/10.3390/medicina57030218

 

Abstract

Background and Objectives: Stress can overload adaptive mechanisms, leading to epigenetic effects harmful to health. Research on the reversal of these effects is in its infancy. Early results suggest some meditation techniques have health benefits that grow with repeated practice. This study focused on possible transcriptomic effects of 38 years of twice-daily Transcendental Meditation® (TM®) practice. Materials and Methods: First, using Illumina® BeadChip microarray technology, differences in global gene expression in peripheral blood mononuclear cells (PBMCs) were sought between healthy practitioners and tightly matched controls (n = 12, age 65). Second, these microarray results were verified on a subset of genes using quantitative polymerase chain reaction (qPCR) and were validated using qPCR in larger TM and control groups (n = 45, age 63). Bioinformatics investigation employed Ingenuity® Pathway Analysis (IPA®), DAVID, Genomatix, and R packages. Results: The 200 genes and loci found to meet strict criteria for differential expression in the microarray experiment showed contrasting patterns of expression that distinguished the two groups. Differential expression relating to immune function and energy efficiency were most apparent. In the TM group, relative to the control, all 49 genes associated with inflammation were downregulated, while genes associated with antiviral and antibody components of the defense response were upregulated. The largest expression differences were shown by six genes related to erythrocyte function that appeared to reflect a condition of lower energy efficiency in the control group. Results supporting these gene expression differences were obtained with qPCR-measured expression both in the well-matched microarray groups and in the larger, less well-matched groups. Conclusions: These findings are consistent with predictions based on results from earlier randomized trials of meditation and may provide evidence for stress-related molecular mechanisms underlying reductions in anxiety, post-traumatic stress disorder (PTSD), cardiovascular disease (CVD), and other chronic disorders and diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

 

re also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wenuganen, S., Walton, K. G., Katta, S., Dalgard, C. L., Sukumar, G., Starr, J., Travis, F. T., Wallace, R. K., Morehead, P., Lonsdorf, N. K., Srivastava, M., & Fagan, J. (2021). Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health. Medicina (Kaunas, Lithuania), 57(3), 218. https://doi.org/10.3390/medicina57030218

 

Abstract

Background and Objectives: Stress can overload adaptive mechanisms, leading to epigenetic effects harmful to health. Research on the reversal of these effects is in its infancy. Early results suggest some meditation techniques have health benefits that grow with repeated practice. This study focused on possible transcriptomic effects of 38 years of twice-daily Transcendental Meditation® (TM®) practice. Materials and Methods: First, using Illumina® BeadChip microarray technology, differences in global gene expression in peripheral blood mononuclear cells (PBMCs) were sought between healthy practitioners and tightly matched controls (n = 12, age 65). Second, these microarray results were verified on a subset of genes using quantitative polymerase chain reaction (qPCR) and were validated using qPCR in larger TM and control groups (n = 45, age 63). Bioinformatics investigation employed Ingenuity® Pathway Analysis (IPA®), DAVID, Genomatix, and R packages. Results: The 200 genes and loci found to meet strict criteria for differential expression in the microarray experiment showed contrasting patterns of expression that distinguished the two groups. Differential expression relating to immune function and energy efficiency were most apparent. In the TM group, relative to the control, all 49 genes associated with inflammation were downregulated, while genes associated with antiviral and antibody components of the defense response were upregulated. The largest expression differences were shown by six genes related to erythrocyte function that appeared to reflect a condition of lower energy efficiency in the control group. Results supporting these gene expression differences were obtained with qPCR-measured expression both in the well-matched microarray groups and in the larger, less well-matched groups. Conclusions: These findings are consistent with predictions based on results from earlier randomized trials of meditation and may provide evidence for stress-related molecular mechanisms underlying reductions in anxiety, post-traumatic stress disorder (PTSD), cardiovascular disease (CVD), and other chronic disorders and diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

 

Improve Diabetes in Older and Elderly Patients with Tai Chi

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Improve Diabetes in Older and Elderly Patients with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Tai Chi exercises can improve blood glucose levels and improve the control of type 2 diabetes and immune system response.” – Medical News Today

 

Diabetes is a major health issue. It is estimated that 30 million people in the United States have diabetes and the numbers are growing. Type 2 Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is the 7th leading cause of death in the United States. In addition, diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

 

Type 2 diabetes is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary lifestyle. Current treatments for Type 2 Diabetes focus on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. Tai Chi is mindfulness practice and a gentle exercise that has been found to improve the symptoms of Type 2 Diabetes. The research is accumulating. So, it is reasonable to examine what has been learned.

 

In today’s Research News article “A Meta-Analysis of the Effects of Tai Chi on Glucose and Lipid Metabolism in Middle-Aged and Elderly Diabetic Patients: Evidence from Randomized Controlled Trials.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007338/ ) Liu and colleagues review, summarize, and perform a meta-analysis of the published randomized controlled studies of the effectiveness of Tai Chi practice in the treatment of Type 2 Diabetes in older and elderly patients. They identified 14 published studies.

 

They report that the published studies found that Tai Chi practice produced significant reductions in fasting blood glucose levels, glycated hemoglobin, cholesterol, triglycerides, and low density lipoproteins, and significantly increased the levels of high density lipoproteins. They report that these improvements occurred predominantly in studies where Tai Chi was practiced for at least 50 minutes per day, for at least 12 weeks.

 

The findings of this meta-analysis suggests that Tai Chi practice is a safe and effective treatment for older and elderly patients with Type 2 Diabetes improving blood glucose and lipid profiles. It is important to note that Tai Chi practice is gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. Hence, Tai Chi practice is an almost ideal treatment for Type 2 Diabetes

 

So, improve diabetes in older and elderly patients with Tai Chi.

 

”Stress stands in the way of controlling diabetes. Since tai chi encourages mental relaxation and reduces stress, it follows that Tai Chi can improve the control of diabetes.” – Paul Lam

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Liu, Y. N., Wang, L., Fan, X., Liu, S., Wu, Q., & Qian, Y. L. (2021). A Meta-Analysis of the Effects of Tai Chi on Glucose and Lipid Metabolism in Middle-Aged and Elderly Diabetic Patients: Evidence from Randomized Controlled Trials. Evidence-based complementary and alternative medicine : eCAM, 2021, 6699935. https://doi.org/10.1155/2021/6699935

 

Abstract

This research review aimed to evaluate the effect of practicing Tai Chi on glucose and lipid metabolism in middle-aged and elderly diabetic patients. Furthermore, it aimed to provide a theoretical basis for the practice of Tai Chi as a way to improve glucose and lipid metabolism in middle-aged and elderly diabetic patients. Therefore, we searched for randomized controlled trials on the practice of Tai Chi in middle-aged and elderly diabetic patients in Chinese- and English-language electronic databases, such as Web of Science, PubMed, the Cochrane Library, EMBASE, Google Scholar, CNKI, Wanfang Database, and Weipu. We collected articles published no later than August 1, 2020. The methodological quality of the included studies was evaluated according to the standards of the Cochrane Collaboration System Evaluation Manual (version 5.1.0). Finally, 14 articles were included, showing an average Physiotherapy Evidence Database scale score of 6.57. The articles were meta-analyzed using Stata 14.0 software, showing that practicing Tai Chi improved middle-aged and elderly diabetic patients’ fasting blood glucose (WMD = −0.60, 95% CI [−1.08, −0.12], p=0.015), glycosylated hemoglobin (WMD = −0.87, 95% CI [−1.60, −0.14], p=0.019), total cholesterol (WMD = −0.48, 95% CI [−0.83, −0.14], p=0.006), triglycerides (WMD = −0.21, 95% CI [−0.37, −0.04], p=0.014), and low-density lipoprotein cholesterol level significantly (WMD = −0.32, 95% CI [−0.63,−0.00], p=0.050). Conversely, patients’ high-density lipoprotein cholesterol levels (WMD = 0.09, 95% CI [−0.01, 0.17], p=0.136) showed no obvious improvement. In conclusion, practicing Tai Chi in sessions lasting longer than 50 minutes (at least three times per week, for at least 12 weeks) can effectively improve glucose and lipid metabolism in middle-aged and elderly diabetic patients. However, several other factors affect glucose and lipid metabolism; therefore, further high-quality research is needed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007338/

 

Produce Lasting Improvements in Resilience and Well-Being in Pre-Retirement Employees with Mindfulness

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Produce Lasting Improvements in Resilience and Well-Being in Pre-Retirement Employees with Mindfulness

 

By John M. de Castro, Ph.D.

 

“workers who took the mindfulness class reported feeling much better. They had less prolonged fatigue — that feeling of exhaustion that doesn’t go away even after having a chance to rest. They also felt less stressed, reported reduced anxiety and depression, and had fewer sleep difficulties, aches and pains, and problems getting along with others.” – Ronald Siegel

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. How we spend that time is immensely important for our psychological, social, and physical health. But nearly 2/3 of employees worldwide are unhappy at work. This is partially due to work-related stress which is epidemic in the western workplace. Almost two thirds of workers reporting high levels of stress at work. This stress can result in impaired health and can result in burnout; producing fatigue, cynicism, and professional inefficacy. This can lead to early retirement.

 

To help overcome unhappiness, stress, and burnout, mindfulness practices have been implemented in the workplace. Indeed, mindfulness practices have been shown to markedly reduce the physiological and psychological responses to stress. As a result, it has become very trendy for business to incorporate meditation into the workday to help improve employee well-being, health, and productivity. These programs attempt to increase the employees’ mindfulness at work and thereby reduce stress. It is not known whether mindfulness will be similarly effective for older employees who are approaching retirement.

 

In today’s Research News article “Pre-retirement Employees Experience Lasting Improvements in Resilience and Well-Being After Mindfulness-Based Stress Reduction.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.699088/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1684212_a0P58000000G0YfEAK_Psycho_20210720_arts_A ) Diachenko and colleagues recruited active employees between the ages of 60-65 years and randomly assigned them to either receive an 8-week program of Mindfulness-Based Stress reduction (MBSR) or to a wait-list control condition. MBSR was delivered in weekly 2.5-hour sessions consisting of meditation, body scan, and yoga along with group discussion and daily 45 minute home practice. After training the participants received monthly 2-hour booster sessions delivered online. They were measured before and after training and 12 months later for perceived stress, resilience, well-being, distress, anxiety, depression, satisfaction with life, quality of thoughts and feelings at rest, and prior experience with yoga and meditation.

 

They found that in comparison to baseline and the wait-list controls, the participants who received Mindfulness-Based Stress reduction (MBSR) had significantly higher levels of resilience, well-being, and comfort in their thoughts at rest, and lower levels of sleepiness that were still significant 12 months later. These findings suggest that MBSR training improves the psychological health of older employees nearing retirement.

 

Mindfulness training has been shown in past research to improve resilience, well-being, and sleep. So, these findings are not surprising. What is new here is that these improvements in psychological health occurred in individuals approaching retirement and these improvements lasted for at least a year after training. It is possible, but not measured, that these improvements may lead to the employees staying in their jobs longer before retirement.

 

So, produce lasting improvements in resilience and well-being in pre-retirement employees with mindfulness.

 

“The most vital parts of mindfulness come not from positive thinking and meditation alone but the business’s approach to its employees.” – Forbes

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Diachenko M, Smith KK, Fjorback L, Hansen NV, Linkenkaer-Hansen K and Pallesen KJ (2021) Pre-retirement Employees Experience Lasting Improvements in Resilience and Well-Being After Mindfulness-Based Stress Reduction. Front. Psychol. 12:699088. doi: 10.3389/fpsyg.2021.699088

 

The socio-economic benefits of interventions to prevent stress and related mental health problems are enormous. In the labor market, it is becoming desirable to keep employees for as long as possible. Since aging implies additional stressors such as increased risk of illness, and added pressure by professional tasks such as transferring knowledge, or learning new technologies, it is of particular relevance to offer stress-reduction to pre-retirement employees. Here, we report the effects of an eight-week Mindfulness-Based Stress Reduction (MBSR) intervention on mental well-being in 60–65-year-old work-active Danish employees, compared to a waiting-list control group. We observed improvements in resilience (Brief Resilience Scale) and mental well-being (WHO-5) not only at the end of the intervention, but also at the 12-month follow-up measurement that was preceded by monthly booster sessions. Interestingly, whereas well-being usually refers to experiences in the past weeks or months, we observed increasing Comfort in the MBSR-intervention group during a 5-minute eyes-closed rest session suggesting that this therapeutic effect of MBSR is measurable in how we feel even during short periods of time. We argue that MBSR is a cost-effective intervention suited for pre-retirement employees to cultivate resilience to prevent stress, feel more comfortable with themselves, maintain a healthy work-life in the last years before retirement, and, potentially, stay in their work-life a few more years than originally planned.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.699088/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1684212_a0P58000000G0YfEAK_Psycho_20210720_arts_A

 

Improve Cognitive Function in Older Adults with Tai Chi Practice

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Improve Cognitive Function in Older Adults with Tai Chi Practice

 

By John M. de Castro, Ph.D.

 

“The practice of Tai Chi promotes the preservation of cognitive abilities including global cognitive functions, semantic memory, verbal learning/memory, self-perception of memory, and visuospatial skills in the elderly.” – Karine Huy-Leng Lim

 

The aging process involves a systematic progressive decline of the body and the brain. Every system in the body deteriorates including cognitive function (thinking ability) and motor function with a decline in strength, flexibility, and balance. There is some hope as there is evidence that these declines can be slowed. For example, a healthy diet and a regular program of exercise can slow the physical and cognitive decline of the body with aging. Also, contemplative practices such as meditation, yoga, and tai chi or qigong have all been shown to be beneficial in slowing or delaying physical and mental decline.

 

Tai Chi has been practiced for thousands of years with benefits for health and longevity. Tai Chi training is designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Tai Chi is not strenuous, involving slow gentle movements, and is safe, having no appreciable side effects, it is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. Tai Chi has been shown to help the elderly improve attention, balance, reducing falls, arthritis, cognitive function, memory, and reduce age related deterioration of the brain. The research has been accumulating. So, it makes sense to step back and summarize what has been learned about the effectiveness of Tai Chi practice for cognition in older adults.

 

In today’s Research News article “Dose-Response Association of Tai Chi and Cognition among Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003349/ ) Chen and colleagues review, summarize, and perform a meta-analysis of the effects of Tai Chi practice on cognitive ability in older adults (55 years old and older) living in the community. They identified 16 published research studies.

 

They report that the published research studies found that Tai Chi practice produced significant improvements in cognitive function with moderate to large effect sizes. But there were no relationships between the amount of Tai Chi practice and the amount of improvement in cognitive function, including session duration, amount of practice per week, or amount of practice over the entire study.

 

These meta-analysis findings suggest that Tai Chi practice has large and significant effects on the high-level thinking ability of community dwelling older adults. It would appear that even the smallest dose of Tai Chi practice is capable of producing these improvements. These improvements in cognition may be important for preventing or mitigating cognitive decline with aging and prevent age related dementia. This makes the safe and fun Tai Chi practice and almost ideal practice for maintaining cognitive ability with aging.

 

So, improve cognitive function in older adults with Tai Chi practice.

 

“A regular tai chi exercise regimen enlarges the brain and enhances the cognitive abilities of the elderly.” – Hans Villarica

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Chen, M. L., Wotiz, S. B., Banks, S. M., Connors, S. A., & Shi, Y. (2021). Dose-Response Association of Tai Chi and Cognition among Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. International journal of environmental research and public health, 18(6), 3179. https://doi.org/10.3390/ijerph18063179

 

Abstract

Previous studies indicated that Tai Chi might be an effective way to improve or prevent cognitive impairments in older populations. However, existing research does not provide clear recommendations about the optimal dose of Tai Chi practice, which is the most effective in improving cognitive function in older adults. The purpose of this systematic review and meta-analysis was to investigate the dose–response relationship between Tai Chi and cognition in community-dwelling older adults. A total of 16 studies with 1121 subjects were included in this study. Meta-regression analyses of Tai Chi duration (Tai Chi session duration, Tai Chi practice duration per week, study duration, and Tai Chi practice duration for the entire study) on the study effect size (ES) were performed to examine the dose–response association of Tai Chi and cognition. The results showed that there was a positive effect of Tai Chi on cognitive function, but there were no statistically significant dose duration effects on cognition. The findings suggest that Tai Chi has beneficial effects on cognitive function, but a longer duration was not associated with larger effects. In order to establish evidence-based clinical interventions using Tai Chi, future research should clearly demonstrate intervention protocol, particularly the style and intensity of Tai Chi.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003349/

 

Improve the Mental, Physical, and Emotional Well-Being of Older Adults During Covid-19 Pandemic with Tai Chi

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Improve the Mental, Physical, and Emotional Well-Being of Older Adults During Covid-19 Pandemic with Tai Chi

 

By John M. de Castro, Ph.D.

 

“Tai Chi Chuan has a potential effect on the prevention, treatment and rehabilitation of COVID-19. Its potential mechanisms include reducing anxiety, relieving depression and stress, enhancing pulmonary and cardiovascular function, enhancing immunity and improving quality of life.” – Chen Xianjian

 

The COVID-19 pandemic has challenged the mental and physical health of the population. It has created intense stress on everyone but particularly the elderly isolating at home. Mindfulness is known to decrease the psychological and physical responses to stress. So, mindfulness training may be helpful in coping with the mental and physical challenges resulting from the COVID-19 pandemic. Tai Chi and Qigong are both mindfulness practices and gentle exercises. They have been shown to be beneficial for the health and well-being of individuals of a variety of ages, but particularly the elderly. So, it would seem reasonable to examine the ability of Tai Chi practice to improve the well-being of older adults during the Covid-19 pandemic.

 

In today’s Research News article “Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054611/ ) Solianik and colleagues recruited healthy sedentary older adults (over 60 years of age) during the Covid-19 pandemic and randomly assigned them to 10 weeks of twice a week for 60 minute Tai Chi practice or to a no treatment control condition. They were measured before and after training for heart rate, perceived stress, anxiety, depression cognitive performance, and motor performance. In addition, blood was drawn and assayed for brain-derived neurotrophic factor.

 

They found that in comparison to baseline and the control group, the older adults who practiced Tai Chi had significantly higher levels of brain-derived neurotrophic factor, high frequency power in the heart rate, visuospatial performance, response inhibition, and shifting mental set, and significantly lower reaction times, heart rate, perceived stress, and depression.

 

The results must be interpreted with the understanding that the control condition was no treatment in a sedentary group of older adults. So, it cannot be determined if the effects were due to Tai Chi itself or exercise in general. Nevertheless, Tai Chi practice resulted in significant improvements in cardiovascular fitness, brain development, cognitive performance, and psychological health.

 

Tai Chi practice is not strenuous, involves slow gentle movements, and is safe, having no appreciable side effects, it is appropriate the elderly. It can also be practiced without professional supervision and in groups making it inexpensive to deliver and fun to engage in. This suggests that during stressful times Tai Chi should be recommended for older adults for their mental, physical, and emotional well-being.

 

So, improve the mental, physical, and emotional well-being of older adults during Covid-19 pandemic with Tai Chi.

 

“Older people should exercise for the entire duration of self-isolation. One large systematic review of falls prevention exercises emphasised the importance of maintaining exercise over time – benefits from Tai Chi were found after 20 weeks.” –  Jamie Hartmann-Boyce

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Solianik, R., Mickevičienė, D., Žlibinaitė, L., & Čekanauskaitė, A. (2021). Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic. Experimental gerontology, 150, 111363. https://doi.org/10.1016/j.exger.2021.111363

 

Abstract

The aim of this study was to determine the effect of a 10-week tai chi intervention on psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic. Participants aged 60–78 years were randomized to either a control group (n = 15) or a tai chi group (n = 15) for a 10-week period. The tai chi group received two, 8-form tai chi classes of 60 min duration per week. Changes in psychoemotional state, cognition, and the learning of fast and accurate reaching movements were assessed. In addition, the potential roles of the autonomic nervous system and brain-derived neurotrophic factor (BDNF) were investigated. Tai chi practice decreased (P < 0.05) perceived stress, whereas no change in autonomic nervous system activity was observed. Improvements in mental switching correlated with decreased depressive symptoms and increased BDNF levels (P < 0.05), whereas improvements in inhibitory control tended to correlate with BDNF levels (P = 0.08). Improvements in visuospatial processing tended to correlate with decreased depressive symptoms (P = 0.07) while improved visuospatial processing correlated with improved motor planning during learning tasks (P < 0.05). This study suggests that tai chi is an effective intervention that can be delivered under pandemic conditions to improve mental and physical function in older adults.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054611/

 

Improve Cognitive Ability in Older Adults with Tai Chi and Qigong Practices

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Improve Cognitive Ability in Older Adults with Tai Chi and Qigong Practices

 

By John M. de Castro, Ph.D.

 

“Qigong exercise induced significant neurocognitive improvement in aging.” – Di Qi

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. The elderly frequently have problems with attention, thinking, and memory abilities, known as mild cognitive impairment. An encouraging new development is that mindfulness practices such as meditation training and mindful movement practices can significantly reduce these declines in cognitive ability.

 

Tai Chi and Qigong have been practiced for thousands of years with benefits for health and longevity. Tai Chi and Qigong trainings are designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Tai Chi and Qigong practice have been found to be effective for an array of physical and psychological issues. Tai Chi and Qigong have been shown to help the elderly improve attention, balance, reducing falls, arthritis, cognitive function, memory, and reduce age related deterioration of the brain. The research findings have been accumulating suggesting that a summarization of what has been learned about the effects of Tai Chi and Qigong practice on the cognitive ability of older adults is called for.

 

In today’s Research News article “Effects of Chinese Mind-Body Exercises on Executive Function in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.656141/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1645362_69_Psycho_20210525_arts_A ) Ren and colleagues review, summarize, and perform a meta-analysis of the published research on the effects of Tai Chi and Qigong practice on the cognitive ability of older adults. They identified 29 published randomized controlled trials employing participants over 50 years of age.

 

They report that the published research found that Tai Chi and Qigong practice produced significant increases in overall executive function including improvements in short-term memory and shifting, the ability to shift from attentional focus to attentional focus. They also found that when practice occurred 5 or more times per week, the effects doubled compared to practice less than 4 times per week.

 

The findings suggest that Tai Chi and Qigong practices are effective in improving thinking in older adults. Since cognitive abilities tend to decline with age, the results suggests that Tai Chi and Qigong practice may protect against age related cognitive decline. This is true especially when practice occurs 5 or more times per week.

 

Some advantages of Tai Chi and Qigong include the facts that they are not strenuous, involve slow gentle movements, are safe, having no appreciable side effects, and are appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It can also be practiced without professional supervision and in groups making it inexpensive to deliver and fun to engage in. This makes Tai Chi and Qigong practice excellent practices for protecting older individuals from age related cognitive decline.

 

So, improve cognitive ability in older adults with Tai Chi and Qigong practices.

 

“Tai chi appears to improve executive function—the ability to multitask, manage time, and make decisions—in people without any cognitive decline. In those with mild cognitive impairment, tai chi slowed the progression to dementia more than other types of exercise and improved their cognitive function in a comparable fashion to other types of exercise or cognitive training.” – Havard Health

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Ren F-F, Chen F-T, Zhou W-S, Cho Y-M, Ho T-J, Hung T-M and Chang Y-K (2021) Effects of Chinese Mind-Body Exercises on Executive Function in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis. Front. Psychol. 12:656141. doi: 10.3389/fpsyg.2021.656141

 

Chinese mind-body exercises (CMBEs) are positively associated with executive function (EF), but their effects on EF, from synthesized evidence using systematic and meta-analytic reviews, have not been conducted. Therefore, the present systematic review with meta-analysis attempted to determine whether CMBEs affect EF and its sub-domains, as well as how exercise, sample, and study characteristics moderate the causal relationship between CMBEs and EF in middle-aged and older adults. Seven electronic databases were searched for relevant studies published from the inception of each database through June 2020 (PubMed, Web of Science, Embase, Cochrane Controlled Trials Register, Wanfang, China National Knowledge Infrastructure, and Weipu). Randomized controlled trials with at least one outcome measure of CMBEs on EF in adults of mean age ≥ 50 years with intact cognition or mild cognitive impairment (MCI) and with or without chronic diseases were included. A total of 29 studies (N = 2,934) ultimately were included in this study. The results indicated that CMBEs improved overall EF (Standardized Mean Differences = 0.28, 95% CI 0.12, 0.44), as well as its sub-domains of working memory and shifting. The beneficial effects of CMBEs on EF occurred regardless of type (Tai Chi, Qigong), frequency of group classes (≤2 time, 3-4 time, ≥5 times), session time (≤45 min, 46-60 min), total training time (≥150 to ≤300 min, >300 min), and length of the CMBEs (4-12 week, 13-26 week, and >26 week), in addition to that more frequent participation in both group classes and home practice sessions (≥5 times per week) resulted in more beneficial effects. The positive effects of CMBEs on EF were also demonstrated, regardless of participants mean age (50-65 years old, >65 years old), sex (only female, both), and cognitive statuses (normal, MCI, not mentioned), health status (with chronic disease, without chronic disease), as well as training mode (group class, group class plus home practice) and study language (English, Chinese). This review thus suggests that CMBEs can be used as an effective method with small to moderate and positive effects in enhancing EF, and that more frequent group classes and home practice sessions may increase these effects. However, certain limitations, including strictly design studies, limited ES (effect size) samples for specific variables, and possible biased publications, required paying particular attention to, for further exploring the effects of CMBEs on EF.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.656141/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1645362_69_Psycho_20210525_arts_A

 

Improve Attention in Older Individuals with Exercise and Mindfulness

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Improve Attention in Older Individuals with Exercise and Mindfulness

 

By John M. de Castro, Ph.D.

 

“engaging in mindfulness meditation training improves the maintenance of goal-directed visuospatial attention and may be a useful strategy for counteracting cognitive decline associated with aging.” – Peter Malinowski

 

One of the primary effects of mindfulness training is an improvement in the ability to pay attention to the task at hand and ignore interfering stimuli. This is an important consequence of mindfulness training and produces improvements in thinking, reasoning, and creativity. The importance of heightened attentional ability to the individual’s ability to navigate the demands of complex modern life cannot be overstated. It helps in school, at work, in relationships, or simply driving a car. As important as attention is, it’s surprising that little is known about the mechanisms by which mindfulness improves attention

 

There is evidence that mindfulness training improves attention by altering the brain. It appears That mindfulness training increases the size, connectivity, and activity of areas of the brain that are involved in paying attention. A common method to study the activity of the nervous system is to measure the electrical signal at the scalp above brain regions. Changes in this activity are measurable with mindfulness training.

 

One method to observe attentional processing in the brain is to measure the changes in the electrical activity that occur in response to specific stimuli. These are called event-related, or evoked, potentials or ERPs. The signal following a stimulus changes over time. The fluctuations of the signal after specific periods of time are thought to measure different aspects of the nervous system’s processing of the stimulus. The N2 response in the evoked potential (ERP) is a negative going electrical response occurring between a 1 to 3 tenths of a second following the target stimulus presentation. The N2 component is thought to reflect cognitive control. The P3 response is a positive going electrical response occurring between a 3 to 6 tenths of a second following the target. The P3 component is thought to reflect attentional processing.

 

In today’s Research News article “Behavioral and ERP Correlates of Long-Term Physical and Mental Training on a Demanding Switch Task.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940199/ ) Burgos and colleagues recruited healthy adults aged 44-65 years. They were separated into groups of participants who practiced for at least 5 years either Tai Chi, Meditation, aerobic exercise, meditation and exercise, or were sedentary. The participants performed a visuospatial task switch test that required the participants to respond to the position of a dot on a screen with the same or opposite hand or to switch back and forth between the two after 2 trials. This measures executive attention. As they were performing the task the electroencephalogram (EEG) was recorded and the evoked potentials to the dot recorded.

 

They found that on the visuospatial task switch test the Tai Chi and Meditation plus exercise groups performed best, the aerobic exercise group intermediate, and the sedentary group worst. Performance was measured by the reaction times on the switch trials and also on the proportionate change in reaction times on switch trials. In the evoked potentials in the frontal and parietal cortical areas, the groups that had mental plus physical training (Tai Chi and Meditation plus exercise groups) had significantly larger N2 responses on switch trials than the meditation or exercise alone groups. They also found that the larger the N2 response the better the performance on the switch task.

 

These are interesting results. But the groups were composed of people who chose to engage in these differing activities and the groups may be composed of people who differ in other ways other than the chosen activity. It would be best in future research if random assignment and training were used. Nevertheless, the results suggest that executive attention is best in people who practice mental and physical exercises. These are superior to either alone and particularly superior to being sedentary.  It was not studied here, but the better performance in attentional ability would predict better overall performance in life and resistance to the mental decline with aging.

 

Both the performance on the task and the N2 responses reflect better executive control of attention. This means that the participants who performed both mindfulness and physical exercise improved their ability to control attention. Mindfulness practices such as Tai Chi and meditation are known to alter the brain and improve attention. But the reason why exercise supplements these benefits is unknown. It is possible that exercise isn’t responsible for improvement but that sedentariness is responsible for deterioration and exercise acts to prevent this deterioration. Nevertheless, the results are clear mindfulness plus physical activity alters the brain in such a way as to improve the individual’s ability to control attention.

 

So, improve attention in older individuals with exercise and mindfulness.

 

“mindfulness may be a way to improve our cognitive control as we age by teaching us to improve our ability to focus our attention on a particular task.” – Holy Tiret

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Burgos, P. I., Cruz, G., Hawkes, T., Rojas-Sepúlveda, I., & Woollacott, M. (2021). Behavioral and ERP Correlates of Long-Term Physical and Mental Training on a Demanding Switch Task. Frontiers in psychology, 12, 569025. https://doi.org/10.3389/fpsyg.2021.569025

 

Abstract

Physical and mental training are associated with positive effects on executive functions throughout the lifespan. However, evidence of the benefits of combined physical and mental regimes over a sedentary lifestyle remain sparse. The goal of this study was to investigate potential mechanisms, from a source-resolved event-related-potential perspective, that could explain how practicing long-term physical and mental exercise can benefit neural processing during the execution of an attention switching task. Fifty-three healthy community volunteers who self-reported long-term practice of Tai Chi (n = 10), meditation + exercise (n = 16), simple aerobics (n = 15), or a sedentary lifestyle (n = 12), aged 47.8 ± 14.6 (SD) were included in this analysis. All participants undertook high-density electroencephalography recording during a switch paradigm. Our results indicate that people who practice physical and mental exercise perform better in a task-switching paradigm. Our analysis revealed an additive effect of the combined practice of physical and mental exercise over physical exercise only. In addition, we confirmed the participation of frontal, parietal and cingulate areas as generators of event-related-potential components (N2-like and P3-like) commonly associated to the performance of switch tasks. Particularly, the N2-like component of the parietal and frontal domains showed significantly greater amplitudes in the exercise and mental training groups compared with aerobics and sedentary groups. Furthermore, we showed better performance associated with greater N2-like amplitudes. Our multivariate analysis revealed that activity type was the most relevant factor to explain the difference between groups, with an important influence of age, and body mass index, and with small effects of educational years, cardiovascular capacity, and sex. These results suggest that chronic combined physical and mental training may confer significant benefits to executive function in normally aging adults, probably through more efficient early attentional processing. Future experimental studies are needed to confirm our results and understand the mechanisms on parieto-frontal networks that contribute to the cognitive improvement associated with practicing combined mental and aerobic exercise, while carefully controlling confounding factors, such as age and body mass index.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940199/

 

 

Improve Physical and Mental Well-Being with Mindfulness Meditation-Based Interventions

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Improve Physical and Mental Well-Being with Mindfulness Meditation-Based Interventions

 

By John M. de Castro, Ph.D.

 

“mindfulness meditation is related to improved mental health across a variety of disorders, including different anxiety disorders, depression, eating disorders, substance abuse, and chronic pain symptom reduction.” – Jennifer Wolkin

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of mental and physical illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented. There is no other treatment or practice that has been shown to come anyway near the range of mindfulness’ positive benefits.

 

Over the last few decades, a vast amount of research has been published on the benefits of mindfulness practices on the mental and physical health of the practitioners. Many reviews, summarizations, and meta-analyses have been performed of these studies. So, it makes sense to step back and summarize what these meta-analyses have found.

 

In today’s Research News article “The empirical status of mindfulness-based interventions: A systematic review of 44 meta-analyses of randomized controlled trials.” (See summary below or view the full text of the study at: https://centerhealthyminds.org/assets/files-publications/Goldberg-the-empirical-status.pdf ) Goldberg and colleagues review, summarize, and perform a meta-analysis of previous meta-analyses of published randomized controlled studies on benefits of sustained meditation practices on mental and physical well-being. They identified 44 published meta-analyses, representing 336 randomized controlled trials, which included a total of 30,483 participants.

 

They report that the meta-analyses of published randomized controlled trials found that sustained mindfulness meditation practices in comparison to passive, no treatment, controls had a very wide range of beneficial effects across a wide range of participants from children to the elderly, over a variety of programs from Mindfulness-Based Stress Reduction (MBSR) to mobile health, over a variety of psychological issues from anxiety to psychoses, and over a wide range of diseases from chronic pain to cancer. These effects were present immediately post treatment and at later follow-ups (an average of 7 months after treatment).

 

Comparison of these mindfulness meditation practices to active control conditions such as attentional controls to evidence-based treatments, resulted in reduced effect sizes and many were non-significant. Mindfulness meditation practices had significantly superior effects than active controls for adults, children, employees, and health care professionals/trainees but not for students. They were superior for psychiatric disorders, substance use, smoking, and depression but not for physical health conditions, pain, weight/eating-related conditions, cancer, or anxiety. They were superior for stress, and psychiatric symptoms but not for sleep, physical health symptoms, objective measures, or physiological measures.

 

These findings are essentially summaries of summaries and are based upon a wide variety of different researchers, methodologies, cultures, and time frames. Yet, the results are fairly consistent. In comparison to doing nothing, passive controls, mindfulness meditation practices are very beneficial for a wide range of physical and psychological issues over a wide range of ages. But these practices when compared to other types of treatments, are less effective and at times not superior. Nevertheless, this meta-analysis of meta-analyses paints a clear picture of the wide-ranging efficacy of mindfulness meditation practices for the relief of physical and psychological issues. These results verify the unprecedented depth and breadth of benefits of mindfulness meditation practices.

 

So, improve physical and mental well-being with mindfulness meditation-based interventions.

 

“Practicing mindfulness exercises can have many possible benefits, including: reduced stress, anxiety and depression, less negative thinking and distraction, and improved mood,” -Mayo Clinic

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Goldberg, S. B., Riordan, K., Sun, S., & Davidson, R. J. (2021). The empirical status of mindfulness-based interventions: A systematic review of 44 meta-analyses of randomized controlled trials. Perspectives on Psychological Science 1–23, DOI: 10.1177/1745691620968771

 

Abstract

In response to questions regarding the scientific basis for mindfulness-based interventions (MBIs), we evaluated their empirical status by systematically reviewing meta-analyses of randomized controlled trials (RCTs). We searched six databases for effect sizes based on ≥4 trials that did not combine passive and active controls. Heterogeneity, moderators, tests of publication bias, risk of bias, and adverse effects were also extracted. Representative effect sizes based on the largest number of studies were identified across a wide range of populations, problems, interventions, comparisons, and outcomes (PICOS). A total of 160 effect sizes were reported in 44 meta-analyses (k=336 RCTs, N=30,483 participants). MBIs showed superiority to passive controls across most PICOS (ds=0.10-0.89). Effects were typically smaller and less often statistically significant when compared to active controls. MBIs were similar or superior to specific active controls and evidence-based treatments. Heterogeneity was typically moderate. Few consistent moderators were found. Results were generally robust to publication bias, although other important sources of bias were identified. Reporting of adverse effects was inconsistent. Statistical power may be lacking in meta-analyses, particularly for comparisons with active controls. As MBIs show promise across some PICOS, future RCTs and meta-analyses should build upon identified strengths and limitations of this literature.

https://centerhealthyminds.org/assets/files-publications/Goldberg-the-empirical-status.pdf

 

Mindfulness is Associated with Medication Adherence in Older Adults

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Mindfulness is Associated with Medication Adherence in Older Adults

 

By John M. de Castro, Ph.D.

 

“Keep a watch…on the faults of the patients, which often make them lie about the taking of things prescribed. For through not taking disagreeable drinks, purgative or other, they sometimes die.” – Hippocrates, Decorum

 

“Integrating mindfulness into our practices may help foster the therapeutic alliance and ultimately medication adherence.” – Michael Ascher

 

In order for prescriptive medications to be effective in treating disease they must be taken. But about 50% of older patients do not take their medications as prescribed and many do not even fill their prescriptions. This is a shockingly high degree of non-compliance that can lead to poorer health and potentially death. Indeed, it has been stated that “increasing the effectiveness of adherence interventions may have a far greater impact on the health of the population than any improvement in specific medical treatments” (R. Brian Haynes). Mindfulness, on the other hand has been shown to be associated with better compliance with therapy and greater health related behaviors. So, it makes sense to study the role of mindfulness in medication adherence in older individuals.

 

In today’s Research News article “Selected psychological predictors of medication adherence in the older adults with chronic diseases.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729554/ ) Gruszczyńska and colleagues recruited older adults, over 60 year of age, who were diagnosed with a chronic disease. They completed measures of medication adherence, health locus of control, stress coping, and mindfulness.

 

They found that the higher the levels of medication adherence, the higher the levels of internal locus of control, influence of others locus of control, and mindfulness and the lower the levels of emotion-oriented coping and distraction seeking. Regression analysis revealed that the strongest positive predictors of medication adherence were influence of others locus of control, and mindfulness while the most powerful negative predictor was emotion-oriented coping.

 

It should be recognized that this study is correlational and as such causation cannot be determined. But these results make sense as ascribing the control of one’s health to other powerful people would suggest that the individual would be more likely to follow the direction of a physician and comply with the medicinal directions. That people who cope with stress emotionally would not adhere to medicinal directions also make sense as the invocation of strong emotions associated with the stress of the disease would be aversive and lead to avoidding or ignoring medicines associated with the source of stress.

 

Finally, mindfulness was found to be influential on medication adherence. Being more aware of and attentive to the needs of the body should lead to tending to those needs and taking prescribed medications to help. Indeed, mindfulness tends to promote health related behaviors in general. In other words, mindful people tend to do things that are beneficial for their health including taking prescribed medications as directed.

 

Since elderly people taking prescribed medications is one of the single most important contributors to their overall health and longevity, improving adherence is extremely important. Perhaps if training in mindfulness was prescribed along with medications, medication adherence may be improved leading to better health outcomes.

 

So, mindfulness is associated with medication adherence in older adults.

 

“Mindfulness interventions have been proven effective on several predictors of poor adherence (i.e., sleep, cognitive impairment, depression, and stress) and thus hold great potential to improve medication adherence.“ – Elena Salmoirago-Blotcher

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Gruszczyńska, M., Wyszomirska, J., Daniel-Sielańczyk, A., & Bąk-Sosnowska, M. (2020). Selected psychological predictors of medication adherence in the older adults with chronic diseases. Nursing open, 8(1), 317–326. https://doi.org/10.1002/nop2.632

 

Abstract

Aim

The main goal of the study was to assess the significance of selected psychological factors related to the adherence to medication recommendations among the older adults with chronic diseases.

Design

It was designed as a cross‐sectional study, aimed at assessing the importance of selected psychological factors in complying with medication recommendations among older adults.

Methods

The study involved 345 older adults with chronic diseases, assessed the importance of selected psychological factors, such as: health locus of control, stress coping and mindfulness in adhering to medication recommendations older persons. To answer the research questions, we performed frequency analyses, basic descriptive statistics analyses together with the Kolmogorov–Smirnov test, Student’s t tests for independent samples, monofactorial analysis of variance in the intergroup diagram, analysis correlation with the Pearson correlation coefficient, Spearman’s rank correlation ρ analysis and stepwise linear regression analysis.

Results

The study identified psychological predictors of medication adherence, which explained 12% of the variability. An emotion‐oriented coping proved to be the most important factor. Additionally, powerful other health locus of control and mindful attention were shown to have a positive effect.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729554/

 

Tai Chi Practice Changes the Brain Differently than Walking

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Tai Chi Practice Changes the Brain Differently than Walking

 

By John M. de Castro, Ph.D.

 

“tai chi appears to improve executive function—the ability to multitask, manage time, and make decisions—in people without any cognitive decline.” – Harvard Health

 

The aging process involves a systematic progressive decline in every system in the body, the brain included. The elderly frequently have problems with attention, thinking, and memory abilities, known as mild cognitive impairment. An encouraging new development is that mindfulness practices such as meditation training and mindful movement practices can significantly reduce these declines in cognitive ability. In addition, it has been found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. Indeed, the brains of practitioners of meditation,  yoga, and Tai Chi have been found to degenerate less with aging than non-practitioners.

 

Tai Chi has been practiced for thousands of years with benefits for health and longevity. Tai Chi training is designed to enhance function and regulate the activities of the body through regulated breathing, mindful concentration, and gentle movements. Tai Chi practice has been found to be effective for an array of physical and psychological issues. Tai Chi has been shown to help the elderly improve attention, balance, reducing falls, arthritis, cognitive function, memory, and reduce age related deterioration of the brain. So, it makes sense to further study the effects of Tai Chi training on the brains of older adults.

 

In today’s Research News article “Differential Effects of Tai Chi Chuan (Motor-Cognitive Training) and Walking on Brain Networks: A Resting-State fMRI Study in Chinese Women Aged 60.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151113/ ) Yue and colleagues recruited older women (over 60 years of age) who were long-term practitioners of Tai Chi or walking and scanned their brains with functional Magnetic Imaging (fMRI).

 

They examined 3 brain networks, the Default Mode Network, the Sensory Motor Network, and the Visual Network and found significant differences in the functional connectivity within these networks between the Tai Chi and walking groups. This suggests that the two exercises change the brains information processing in these women. They suggest that the brains of the older women went through neuroplastic changes as a result of their practices with different changes in different systems depending on the exercise.

 

There is evidence that physical fitness reduces the likelihood of dementia and Tai Chi practice has been shown to reduce the likelihood or severity of age-related cognitive decline. The observed changes, particularly in the Default Mode Network, which is known to be associated with memory and thinking, may underlie the effectiveness of these exercises in reducing the incidence of age-related cognitive decline and dementia. It remains for future research to determine which of the observed changes in the brains are responsible for retaining mental ability with aging.

 

Tai Chi practice is not strenuous, involves slow gentle movements, and is safe, having no appreciable side effects, it is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It can also be practiced without professional supervision and in groups making it inexpensive to deliver and fun to engage in. This makes Tai Chi practice an excellent means to maintain fitness with aging and help maintain a fit mind and body.

 

So, Tai Chi practice changes the brain differently than walking.

 

“Scientists . . . found increases in brain volume and improvements on tests of memory and thinking in Chinese seniors who practiced Tai Chi.” – ScienceDaily

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Yue, C., Zhang, Y., Jian, M., Herold, F., Yu, Q., Mueller, P., Lin, J., Wang, G., Tao, Y., Zhang, Z., & Zou, L. (2020). Differential Effects of Tai Chi Chuan (Motor-Cognitive Training) and Walking on Brain Networks: A Resting-State fMRI Study in Chinese Women Aged 60. Healthcare (Basel, Switzerland), 8(1), 67. https://doi.org/10.3390/healthcare8010067

 

Abstract

Background: This cross-sectional study aimed to investigate whether a long-term engagement in different types of physical exercise may influence resting-state brain networks differentially. In particular, we studied if there were differences in resting-state functional connectivity measures when comparing older women who are long-term practitioners of tai chi chuan or walking. Method: We recruited 20 older women who regularly practiced tai chi chuan (TCC group), and 22 older women who walked regularly (walking group). Both the TCC group and the walking group underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. The acquired rs-fMRI data of all participants were analyzed using independent component analysis. Age and years of education were added as co-variables. Results: There were significant differences in default network, sensory-motor network, and visual network of rs-fMRI between the TCC group and walking group (p < 0.05). Conclusions: The findings of the current study suggested that long-term practice of different types of physical exercises (TCC vs. walking) influenced brain functional networks and brain functional plasticity of elderly women differentially. Our findings encourage further research to investigate whether those differences in resting-state functional connectivity as a function of the type of physical exercise have implications for the prevention of neurological diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151113/