Lower Opioid Cravings are Associated with Lower Depression, Higher Self-Regulation, and Higher Mindfulness

Lower Opioid Cravings are Associated with Lower Depression, Higher Self-Regulation, and Higher Mindfulness

 

By John M. de Castro, Ph.D.

 

mindfulness-based interventions could help people dependent on opioids increase their self-awareness and self-control over cravings and be less reactive to emotional and physical pain.” – Science Daily

 

Substance abuse and addiction is a terrible problem, especially opioid pain relievers. Opioid addiction has become epidemic and is rapidly increasing affecting more than 2 million Americans and an estimated 15 million people worldwide. In the U.S more than 20,000 deaths yearly were attributed to an overdose of prescription opioids, and another 13,000 deaths from heroin overdose. These statistics, although startling are only the tip of the iceberg. Drug use is associated with suicide, homicide, motor-vehicle injury, HIV infection, pneumonia, violence, mental illness, and hepatitis. It can render the individual ineffective at work, it tears apart families, it makes the individual dangerous both driving and not.

 

An effective treatment for addiction has been elusive. Most programs and therapies to treat addictions have poor success rates. Recent research is indicating that mindfulness has been found to be effective in treating addictions. One way that mindfulness may produce these benefits is by reducing cravings for opioids. It may also do so by affecting the ability of the addict to regulate their emotions. Indeed, mindfulness has been shown to improve emotional regulation.

 

In today’s Research News article “Autonomic and affective mediators of the relationship between mindfulness and opioid craving among chronic pain patients. Experimental and clinical psychopharmacology.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355352/), Baker and Garland recruited non-cancer chronic pain patients who were taking opioid analgesics and had them complete self-report measures of mindfulness, opioid craving, and depression. They also measured their heart rates with an electrocardiogram (ECG) while looking at either neutral pictures or “opioid-related image (e.g., pills, pill bottles).” These data were analyzed to determine heart rate variability as a measure of the activity of the peripheral autonomic nervous system.

 

They found that the higher the levels of mindfulness the higher the levels of heart rate variability while looking at opioid-related pictures. And the lower the levels of depression and opioid cravings. Also, the higher the levels of depression, the higher the levels of opioid cravings. Employing a multivariate path analysis, they found that mindfulness was not associated with lower opioid cravings directly, but indirectly via mindfulness’ associations with heart rate variability and depression. That is, they found that mindfulness was associated with higher heart rate variability which was in turn associated with lower opioid cravings and also with lower depression which was in turn associated with lower opioid cravings.

 

Heart rate variability is thought to measure the nervous systems adjustments to the physiology involved in regulating its physical responses to stimuli. In other words, it’s a measure of self-regulation. The present results suggest that mindfulness is associated with greater self-regulation and this is associated with lower cravings for opioids. The results also suggest that depression is associated with higher cravings for opioids and that mindfulness interrupts this by being associated with lower depression.

 

These results are correlative and as such causation cannot be determined. Nevertheless, prior research has demonstrated causal links between mindfulness and lower cravings and depression. So, the present results likely result from causal connections. The findings also suggest the mechanism whereby mindfulness may lower cravings by contributing to the ability to regulate physical responses to opioid-related stimuli and by reducing depression. These results provide more support for the use of mindfulness training as a treatment for addictions.

 

So, lower opioid cravings are associated with lower depression, higher self-regulation, and higher mindfulness.

 

people suffering from opioid addiction and chronic pain may have fewer cravings and less pain when adding mindfulness to the traditional methadone treatment.” – Grace Bullock

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Baker, A. K., & Garland, E. L. (2019). Autonomic and affective mediators of the relationship between mindfulness and opioid craving among chronic pain patients. Experimental and clinical psychopharmacology, 27(1), 55–63. https://doi.org/10.1037/pha0000225

 

Abstract

Prescription opioid misuse among chronic pain patients is associated with self-regulatory deficits, affective distress and opioid cue reactivity. Dispositional mindfulness has been associated with enhanced self-regulation, lower distress, and adaptive autonomic responses following drug cue exposure. We hypothesized that dispositional mindfulness might serve as a protective factor among opioid-treated chronic pain patients. We examined heart rate variability (HRV) during exposure to opioid cues and depressed mood as mediators of the association between dispositional mindfulness and opioid craving. Data were obtained from a sample of chronic pain patients (N=115) receiving long-term opioid pharmacotherapy. Participants self-reported opioid craving and depression, and HRV was measured during an opioid-cue dot probe task. Dispositional mindfulness was significantly positively correlated with HRV, and HRV was significantly inversely associated with opioid craving. Dispositional mindfulness was significantly negatively correlated with depression, and depression was significantly positively correlated with opioid craving. Path analysis revealed significant indirect effects of dispositional mindfulness on craving through both HRV and depression. Dispositional mindfulness may buffer against opioid craving among chronic pain patients prescribed opioids; this buffering effect may be a function of improved autonomic and affective responses.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355352/

 

Online Mindfulness Training Improves Clinical Anxiety and Depression

Online Mindfulness Training Improves Clinical Anxiety and Depression

 

By John M. de Castro, Ph.D.

 

“adding MMB [mindfulness training] to depression care led to greater reductions in depressive and anxious symptoms, higher rates of remission and higher levels of quality of life compared to patients receiving conventional depression care alone.” – Traci Pederson

 

Mindfulness training has been shown through extensive research to be effective in improving physical and psychological health and particularly with the physical and psychological reactions to stress. They have been shown to be very helpful in treating anxiety and depression. The vast majority of the mindfulness training techniques, however, require a certified trained therapist. This results in costs that many clients can’t afford. In addition, the participants must be available to attend multiple sessions at particular scheduled times that may or may not be compatible with their busy schedules and at locations that may not be convenient.

 

As an alternative, mindfulness training programs have been developed to be implemented over the internet. These have tremendous advantages in decreasing costs, making training schedules much more flexible, and eliminating the need to go repeatedly to specific locations. But, the question arises as to which forms of online mindfulness trainings are most effective for inducing mindfulness and improving the treatment of anxiety and depression.

 

In today’s Research News article “Transdiagnostic internet-delivered CBT and mindfulness-based treatment for depression and anxiety: A randomised controlled trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044661/), Kladnitski and colleagues recruited online adults with a variety of either depression or anxiety disorders and randomly assigned them to receive either a 17-week internet-based cognitive behavioral therapy, mindfulness enhanced internet-based cognitive behavioral therapy, internet-based mindfulness training, or treatment-as-usual. “The programs consisted of six comic-style, story-based lessons, downloadable lesson summaries, reflective worksheets, and extra support materials including frequently asked questions and troubleshooting of common difficulties.” They were measured before, during, and after treatment and 3 months later for psychological illnesses, anxiety, depression, psychological distress, and functional impairment.

 

They found compared to baseline and the treatment-as-usual control group, there were large and highly significant decreases in anxiety, depression, functional impairment and psychological distress. These improvements were present both at the end of treatment and at the 3-month follow-up. There were no significant differences between the effectiveness of the 3 interventions. There were no adverse events reported. At the 3-month follow-up 60% to 73% of the treated participants improved to the point that they no longer met the criteria for a clinical diagnosis of an anxiety or depressive disorder.

 

It is interesting that the 3 different treatments did not differ in effectiveness. Each has been previously been demonstrated to be effective in treating anxiety and depressive disorders and it appears that their efficacy is almost equivalent. This suggests that patients can self-select the treatment that most appeals to them, improving completion rates, compliance, and perhaps effectiveness.

 

These are exciting and important findings. It has been previously demonstrated that mindfulness training can alleviate the symptoms of anxiety and depression. The advance here is in demonstrating that therapy delivered over the internet is safe, effective, and lasting in treating anxiety or depressive disorders. Internet delivery of treatment can be implemented conveniently, at low cost. and over wide areas making the therapy available to large numbers of patients who previously could not access treatment.

 

So, online mindfulness training improves clinical anxiety and depression.

 

Mindfulness and other meditations, particularly combined with cognitive therapy, work just as well for anxiety or depression as the medications do, but they don’t have those side effects,” – Daniel Goleman

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kladnitski, N., Smith, J., Uppal, S., James, M. A., Allen, A. R., Andrews, G., & Newby, J. M. (2020). Transdiagnostic internet-delivered CBT and mindfulness-based treatment for depression and anxiety: A randomised controlled trial. Internet Interventions, 20, 100310. https://doi.org/10.1016/j.invent.2020.100310

 

Abstract

Aim

To examine the efficacy of transdiagnostic internet-delivered cognitive behavioural therapy (iCBT), mindfulness-enhanced iCBT, and stand-alone online mindfulness training compared with a usual care control group (TAU) for clinical anxiety and depression.

Method

Individuals (N = 158) with a DSM-5 diagnosis of a depressive and/or anxiety disorder were randomised to one of the three clinician-guided online interventions, or TAU over a 14-week intervention period. The primary outcomes were self-reported depression (PHQ-9) and anxiety (GAD-7) severity at post-treatment. Secondary outcomes included adherence rates, functional impairment (WHODAS-II), general distress (K−10), and diagnostic status at the 3-month follow-up (intervention groups).

Results

All three programs achieved significant and large reductions in symptoms of depression (g = 0.89–1.53), anxiety (g = 1.04–1.40), and distress (g = 1.25–1.76); and medium to large reductions in functional impairment (g = 0.53–0.98) from baseline to post-treatment and 3-month follow-up. Intention-to-treat linear mixed models showed that all three online programs were superior to usual care at reducing symptoms of depression (g = 0.89–1.18) and anxiety (g = 1.00–1.23).

Conclusion

Transdiagnostic iCBT, mindfulness-enhanced iCBT and online mindfulness training are more efficacious for treating depression and anxiety disorders than usual care, and represent an accessible treatment option for these disorders.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044661/

 

Mindfulness Improves Depression in Real-World Healthcare Applications

Mindfulness Improves Depression in Real-World Healthcare Applications

 

By John M. de Castro, Ph.D.

 

Rather than try to avoid or eliminate sadness or other negative emotions, one learns to change their relationship with these emotions by practicing meditation and other mindfulness exercises.” – Psychology Today

 

Clinically diagnosed depression is the most common mental illness, affecting over 6% of the population. Major depression can be quite debilitating. Depression can be difficult to treat and is usually treated with anti-depressive medication. But, of patients treated initially with drugs only about a third attained remission of the depression. After repeated and varied treatments including drugs, therapy, exercise etc. only about two thirds of patients attained remission. But drugs often have troubling side effects and can lose effectiveness over time. In addition, many patients who achieve remission have relapses and recurrences of the depression. Even after remission some symptoms of depression may still be present (residual symptoms).

 

Being depressed and not responding to treatment or relapsing is a terribly difficult situation. The patients are suffering and nothing appears to work to relieve their intense depression. Suicide becomes a real possibility. So, it is imperative that other treatments be identified that can relieve the suffering. Mindfulness training is an alternative treatment for depression. It has been shown to be an effective treatment for depression and its recurrence and even in the cases where drugs failMindfulness-Based Cognitive Therapy (MBCT) was specifically developed to treat depression. MBCT involves mindfulness training, containing sitting, walking and body scan meditations, and cognitive therapy that attempts to teach patients to distinguish between thoughts, emotions, physical sensations, and behaviors, and to recognize irrational thinking styles and how they affect behavior.

 

There has been considerable research demonstrating that Mindfulness-Based Cognitive Therapy (MBCT) is effective in treating depression. Most of the work has been done in controlled research situations. At this point an examination is needed of how effective MBCT is when employed routinely in healthcare settings.

 

In today’s Research News article “The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995449/), Tickell and colleagues extracted the data from 1554 participants in group Mindfulness-Based Cognitive Therapy (MBCT) programs. They obtained data on the patients sociodemographic status, depression levels and attendance at MBCT sessions.

 

On average the patients attended 6.37 of the 8 MBCT sessions. They report that after the Mindfulness-Based Cognitive Therapy (MBCT) program there was significant reductions in depression with small to medium effect sizes. Of those participants who were clinically depressed 45% were recovered and 34% were reliably recovered after MBCT. There were no differences in improvement in depression for different ages or genders.

 

These results were not from highly controlled randomized clinical trials. Rather they were from real-world clinical applications of Mindfulness-Based Cognitive Therapy (MBCT) for the treatment of depression. There is ample evidence from controlled trials that mindfulness training and MBCT in particular are effective in reducing depression. The strength of the current study is that it demonstrates that when MBCT is implemented by clinicians in typical treatment settings it is also effective in reducing depression.

 

So, mindfulness improves depression in real-world healthcare applications.

 

Mindfulness and other meditations, particularly combined with cognitive therapy, work just as well for anxiety or depression as the medications do, but they don’t have those side effects,” – Daniel Goleman

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Tickell, A., Ball, S., Bernard, P., Kuyken, W., Marx, R., Pack, S., Strauss, C., Sweeney, T., & Crane, C. (2020). The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services. Mindfulness, 11(2), 279–290. https://doi.org/10.1007/s12671-018-1087-9

 

Abstract

Depression is common with a high risk of relapse/recurrence. There is evidence from multiple randomised controlled trials (RCTs) demonstrating the efficacy of mindfulness-based cognitive therapy (MBCT) for the prevention of depressive relapse/recurrence, and it is included in several national clinical guidelines for this purpose. However, little is known about whether MBCT is being delivered safely and effectively in real-world healthcare settings. In the present study, five mental health services from a range of regions in the UK contributed data (n = 1554) to examine the impact of MBCT on depression outcomes. Less than half the sample (n = 726, 47%) entered with Patient Health Questionnaire (PHQ-9) scores in the non-depressed range, the group for whom MBCT was originally intended. Of this group, 96% sustained their recovery (remained in the non-depressed range) across the treatment period. There was also a significant reduction in residual symptoms, consistent with a reduced risk of depressive relapse. The rest of the sample (n = 828, 53%) entered treatment with PHQ-9 scores in the depressed range. For this group, 45% recovered (PHQ-9 score entered the non-depressed range), and overall, there was a significant reduction in depression severity from pre-treatment to post-treatment. For both subgroups, the rate of reliable deterioration (3%) was comparable to other psychotherapeutic interventions delivered in similar settings. We conclude that MBCT is being delivered effectively and safely in routine clinical settings, although its use has broadened from its original target population to include people experiencing current depression. Implications for implementation are discussed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995449/

 

Improve Body Size, Endocrine Function, and Anxiety in Anxious Obese Children with Mindfulness

Improve Body Size, Endocrine Function, and Anxiety in Anxious Obese Children with Mindfulness

 

By John M. de Castro, Ph.D.

 

Mindfulness is a promising tool to be used as an adjunctive therapy for childhood obesity, either because of its potential to decrease stress or because it could counter act the stressful condition imposed by a restrictive dietary regimen,” – Mardia López-Alarcón

 

Obesity has become an epidemic in the industrialized world. In the U.S. the incidence of obesity, defined as a Body Mass Index (BMI) of 30 or above has more than doubled over the last 35 years to currently around 35% of the population, while two thirds of the population are considered overweight or obese (BMI > 25). Sadly, children and adolescents have not been spared with 1 in 5 school age children and young people (6 to 19 years) classified as obese.

 

Although the incidence rates have appeared to stabilize, the fact that over a third of the population is considered obese is very troubling. This is because of the health consequences of obesity. Obesity has been found to shorten life expectancy by eight years and extreme obesity by 14 years. This occurs because obesity is associated with cardiovascular problems such as coronary heart disease and hypertension, stroke, metabolic syndrome, diabetes, cancer, arthritis, and others.

 

Obviously, there is a need for effective treatments to prevent or treat obesity. But, despite copious research and a myriad of dietary and exercise programs, there still is no safe and effective treatment. Mindfulness is known to be associated with lower risk for obesityalter eating behavior and improve health in obesity. This suggests that mindfulness training may be an effective treatment for overeating and obesity in children alone or in combination with other therapies. It would seem reasonable to attack the problem early in life with the children and adolescents. Hence, the benefits of mindfulness practice for obese children should be investigated.

 

In today’s Research News article “Mindfulness affects stress, ghrelin, and BMI of obese children: a clinical trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040861/), López-Alarcón and colleagues recruited obese children and adolescents aged 10-17 years who scored high in anxiety levels and provided them with an 8-week, once a week for a half hour conventional nutritional intervention including recommendations for a 700 Kcal reduction in intake. They were then randomly assigned to receive either no further treatment or to receive an 8-week, once a week for 2 hours Mindfulness-Based Stress Reduction-Eat Mindful program based upon the Mindfulness-Based Stress Reduction (MBSR) program consisting on training in meditation, body scan, breathing exercises, mindful eating, and discussions of using mindfulness in everyday life. They were measured before and after the program and 8 weeks later for body size, perceived stress, and anxiety. Blood was drawn and assayed for insulin, cortisol, ghrelin, and leptin and a salivary sample was assayed for cortisol levels.

 

They found that in comparison to the baseline and the nutritional intervention only, the children and adolescents who received mindfulness training had significant reduction in anxiety levels of all forms, including phobias, generalized anxiety, obsessive-compulsive disorder, and separation anxiety. Also, there were significant reductions in body fat, cortisol, and ghrelin levels. In addition, at the 8- and 16-week follow-ups there were significant reductions in body size.

 

These are exciting results. Childhood obesity is major problem and the results of this study suggests that a mindfulness training program combined with a conventional nutritional intervention is safe and effective in improving the physical and psychological effects of obesity and in reducing body size. Mindfulness interventions have been shown to be effective in reducing anxiety in adults. But these programs have been found to have only small or mixed effectiveness in the treatment of adult obesity. But the present results suggest that mindfulness interventions may be particularly effective when applied to obese children and adolescents. A long-term follow up of these children is needed to determine the long-term effectiveness of mindfulness training.

 

So, improve body size, endocrine function, and anxiety in anxious obese children with mindfulness.

 

We think mindfulness could recalibrate the imbalance in the brain connections associated with childhood obesity,” – Ronald Cowan

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

López-Alarcón, M., Zurita-Cruz, J. N., Torres-Rodríguez, A., Bedia-Mejía, K., Pérez-Güemez, M., Jaramillo-Villanueva, L., Rendón-Macías, M. E., Fernández, J. R., & Martínez-Maroñas, P. (2020). Mindfulness affects stress, ghrelin, and BMI of obese children: a clinical trial. Endocrine connections, 9(2), 163–172. https://doi.org/10.1530/EC-19-0461

 

Abstract

Childhood obesity is associated with stress. However, most treatment strategies include only dietary and physical activity approaches. Mindfulness may assist in weight reduction, but its effectiveness is unclear. We assessed the effect of mindfulness on stress, appetite regulators, and weight of children with obesity and anxiety. A clinical study was conducted in a pediatric hospital. Eligible children were 10–14 years old, BMI ≥95th percentile, Spence anxiety score ≥55, and who were not taking any medication or supplementation. Participants were assigned to receive an 8-week conventional nutritional intervention (CNI) or an 8-week mindfulness-based intervention plus CNI (MND-CNI). Anthropometry, body composition, leptin, insulin, ghrelin, cortisol, and Spence scores were measured at baseline and at the end of the intervention. Anthropometry was analyzed again 8 weeks after concluding interventions. Log-transformed and delta values were calculated for analysis. Thirty-three MND-CNI and 12 CNI children finished interventions; 17 MND-CNI children accomplished 16 weeks. At the end of the intervention, significant reductions in anxiety score (−6.21 ± 1.10), BMI (−0.45 ± 1.2 kg/m2), body fat (−1.28 ± 0.25%), ghrelin (−0.71 ± 0.37 pg/mL), and serum cortisol (−1.42 ± 0.94 µg/dL) were observed in MND-CNI children. Changes in anxiety score, ghrelin, and cortisol were different between groups (P < 0.05). Children who completed 16 weeks decreased BMI after intervention (−0.944 ± 0.20 kg/m2, P < 0.001) and remained lower 8 weeks later (−0.706 ± 0.19 kg/m2, P = 0.001). We concluded that mindfulness is a promising tool as an adjunctive therapy for childhood obesity. However, our findings need confirmation in a larger sample population.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040861/

 

Mindful Nurses are Better Nurses

Mindful Nurses are Better Nurses

 

By John M. de Castro, Ph.D.

 

“Mindfulness practice helps nurses to be more fully present with their patients and themselves. The ability to pay attention to what is happening “right now,” in this room with this patient, and not be distracted by other demands and concerns, creates space to use your wisdom and knowledge effectively and with care for the dignity of each patient. Being more present to your own experience and habitual responses increases your ability to manage stress and enhances decision-making, well-being, and self-efficacy.” – Sandra Bernstein

 

In high stress occupations, like nursing, burnout is all too prevalent. Burnout is the fatigue, cynicism, emotional exhaustion, sleep disruption, and professional inefficacy that comes with work-related stress. It is estimated that over 45% of healthcare workers experience burnout. It not only affects the healthcare providers personally, but also the patients, as it produces a loss of empathy and compassion. Burnout, in fact, it is a threat to the entire healthcare system. Currently, over a third of healthcare workers report that they are looking for a new job. Hence, burnout contributes to the shortage of doctors and nurses.

 

It is beyond the ability of the individual to change the environment to reduce stress and prevent burnout. So, it is important that methods be found to reduce the individual’s responses to stress; to make the individual more resilient when high levels of stress occur and thereby make them better in their roles as healthcare providers. Mindfulness has been shown to reduce the psychological and physiological responses to stress and improve well-being. Indeed, mindfulness has been shown to be helpful in treating and preventing burnoutincreasing resilience, and improving sleep. Hence, mindfulness may be a means to reduce burnout and improve well-being, dedication, and compassion in nurses.

 

In today’s Research News article “The mediating role of cognitive and affective empathy in the relationship of mindfulness with engagement in nursing.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947930/), Pérez-Fuentes and colleagues recruited Spanish nurses and had them complete measures of mindfulness, empathy, including measures of cognitive and affective empathy, and work engagement including measures of vitality, dedication and absorption.

 

A correlational analysis revealed that the higher the level of mindfulness the higher the level of work engagement including vitality, dedication and absorption and cognitive empathy, and the lower the level of affective empathy. A mediation analysis of these data revealed that mindfulness had direct associations and also indirect associations via cognitive empathy with higher work engagement including vitality, dedication and absorption. That is that mindfulness was directly associated with work engagement and also indirectly associated as a result of mindfulness being associated with higher cognitive empathy that was, in turn, associated with higher work engagement.

 

These findings are correlational and as such causation cannot be established. Nevertheless, the findings suggest that mindful nurses have greater levels of energy (vigor), feel greater challenge and enthusiasm for their work (dedication), have greater attention to and concentration on their work (absorption), and have a better intellectual understanding of the feelings of others (cognitive empathy). In addition, mindful nurses, because they have higher levels of cognitive empathy, have additionally higher levels of work engagement.

 

These findings suggest that mindfulness is an important contributor to the work engagement, vigor, and absorption of nurses. This suggests that mindful nurses are better nurses. Future research should attempt to determine causation by training the nurses in mindfulness and observing whether work engagement increases and burnout decreases as a result of the training.

 

So, mindful nurses are better nurses.

 

Nursing is a high-stress profession that may be taking a toll on our nurses. Mindfulness-based programs can help nurses develop skills to manage clinical stress and improve their health; increase overall attention, empathy, and presence with patients and families; and experience work satisfaction, serenity, decreased incidental overtime, and reduced job burnout.” – Sue Penque

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Pérez-Fuentes, M., Gázquez Linares, J. J., Molero Jurado, M., Simón Márquez, M., & Martos Martínez, Á. (2020). The mediating role of cognitive and affective empathy in the relationship of mindfulness with engagement in nursing. BMC public health, 20(1), 16. https://doi.org/10.1186/s12889-019-8129-7

 

Abstract

Background

The work of health professionals is characterized by a high demand for psychological and emotional resources and high levels of stress. Therefore, the promotion of commitment and job well-being through strategies such as increased mindfulness, is important among nursing workers. Although mindfulness has shown positive effects in the health field, few studies have explored the mechanisms and processes underlying these results. We investigated the mediating role of empathy (cognitive/affective) in the effect of mindfulness on the dimensions of engagement in nursing professionals.

Methods

Sample was comprised of 1268 Spanish nurses between 22 and 62 years old, that completed the Utrecht Labor Engagement Scale and the adapted versions of Mindful Attention Awareness Scale and Basic Empathy Scale. The relationship between variables to be included in the regression analyses, bivariate correlations were carried out, and the descriptive statistics of these variables were also found. To estimate the mediation model was used, in this case for multiple mediation effects.

Results

Mindfulness is found to affect the Vigor and Dedication factors of engagement through cognitive empathy. While for the Absorption factor, the affective component of empathy also exerts a mediating role, although weaker than cognitive empathy. Cognitive empathy, as an individual factor, was shown to have a mediating effect between mindfulness and the factors of engagement in healthcare workers.

Conclusions

The level of mindfulness influences engagement of nursing professionals positively, and this result is mediated mainly by cognitive empathy. Both mindfulness and empathy are modifiable individual factors, so their intervention by designing and implementing specific programs, can increase the commitment and wellbeing of professionals generating benefits to workers and to their patients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947930/

 

Improve the Quality of Life of Multiple Sclerosis Patients with Mindfulness

Improve the Quality of Life of Multiple Sclerosis Patients with Mindfulness

 

By John M. de Castro, Ph.D.

 

mindfulness can improve quality of life and help people cope better with their MS. Various studies found that mindfulness decreased pain, stress, anxiety and depression.” – MS Trust

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis.  Mindfulness-Based Stress Reduction (MBSR) is a mindfulness training program that involves meditation, yoga, body scan, discussion. and daily practice at home.

 

In today’s Research News article “The Effect of Mindfulness-Based Stress Reduction (MBSR) Therapy on Quality of Life in Women with Multiple Sclerosis, Ahvaz, Iran.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942645/), Kolahkaj and colleagues examine the ability of MBSR training to improve the quality of life of women with Multiple Sclerosis (MS). They recruited women with Multiple Sclerosis and randomly assigned them to receive either a 2-hour, once a week, for 8 weeks program of Mindfulness-Based Stress Reduction (MBSR) or treatment as usual. They were measured before and after treatment and 2 months later for quality of life, pain, physical function, and mental and physical health.

 

They found that in comparison to baseline and the treatment as usual group, the patients who received Mindfulness-Based Stress Reduction (MBSR) practice had significantly better general health, physical function, vitality, mental health, physical, social, and emotional quality of life, and bodily pain.

 

These results are quite striking and corroborate previous findings that mindfulness training can significantly improve the mental health and quality of life of patients with Multiple Sclerosis. Future research should include an active comparison condition such as exercise to eliminate potential bias effects. Nevertheless, the results clearly demonstrate that mindfulness training markedly improvove the physical and mental condition of women with Multiple Sclerosis.

 

So, improve the quality of life of Multiple Sclerosis patients with mindfulness.

 

Mindfulness helped them begin to let go of the frustration that they can’t control [the disease],” They were able to accept their MS, reduce their stress, and hopefully, improve the quality of their lives.” – Ed Tobias

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kolahkaj, B., Zargar, F., & Majdinasab, N. (2018). The Effect of Mindfulness-Based Stress Reduction (MBSR) Therapy on Quality of Life in Women with Multiple Sclerosis, Ahvaz, Iran. Journal of caring sciences, 8(4), 213–217. https://doi.org/10.15171/jcs.2019.030

 

Abstract

Introduction: Low quality of life is one of the most common symptoms of Multiple Sclerosis (MS) which can reduce satisfaction with life, as well as increase death ratio and neuro-mental problems. The present study aimed to determine the effect of Mindfulness-Based Stress Reduction (MBSR) therapy on the quality of life in women with Multiple sclerosis in the city of Ahvaz.

Methods: Forty eight patients who had referred to neurologists were selected by convenient sampling and were assigned into two groups (MBSR and control) randomly. The participants of the two groups answered the 36-item quality of life questionnaire. The experimental group was under treatment for 8 sessions while the control group did not receive any psychological treatment. Data were analyzed, using SPSSver.13 software by repeated measures analysis of variance.

Results: In the MBSR group, the mean subscales of QOL had more significant reduction compare to control group. Also the improvement of all subscales of mental and physical QOL continued after two months later in follow up stage.

Conclusion: The findings suggest that MBSR is useful for improving the quality of life in patients with MS.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942645/

 

Improve Emotion Regulation and Attention with Zen Meditation

Improve Emotion Regulation and Attention with Zen Meditation

 

By John M. de Castro, Ph.D.

 

Meditation can give you a sense of calm, peace and balance that can benefit both your emotional well-being and your overall health. And these benefits don’t end when your meditation session ends. Meditation can help carry you more calmly through your day and may help you manage symptoms of certain medical conditions.” – Mayo Clinic

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of mental and physical illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented. There is no other treatment or practice that has been shown to come anyway near the range of mindfulness’ positive benefits.

 

There is a vast array of techniques for the development of mindfulness. They include a variety of forms of meditationyogamindful movementscontemplative prayer, and combinations of practices. Zen meditation has been practiced for centuries but has only recently been studied with empirical science.

 

In today’s Research News article “Zen meditation neutralizes emotional evaluation, but not implicit affective processing of words.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029852/), Lusnig and colleagues recruited adult experienced meditators and meditation naïve participants. The meditators engaged in a 90-minute Zen meditation session while the control group watched a neutral 90-minute documentary movie. They were measured before and after the session for attention, concentration, intelligence, and personality, and performed a lexical decision task to positive and negative emotion laden words, and neutral words varying in arousal level. They also reported the emotional valence of the words from -3 as very negative to +3 as very positive.

 

They found that in comparison to baseline and the comparison group after the single meditation session, the meditators rated the valence of the emotion laden words as more neutral and detected words significantly faster. The researchers interpreted these findings as indicative of meditation increasing attention (faster response times) and decreasing emotionality (neutralized valence ratings).

 

These findings are not surprising in that previous research has demonstrated that mindfulness practices improve attention and improve emotion regulation. They are surprising, however, in demonstrating that a single meditation session with experienced meditators is sufficient to activate these effects. It would have been interesting to also look at the effects of a meditation session on the meditation naïve participants to determine if the effects were due to meditation in general or to a difference in the effects of meditation on experienced versus naïve meditators.

 

So, improve emotion regulation and attention with Zen meditation.

 

mindfulness meditation preaches accepting and letting go of negative emotions. Practicing this sort of behavior, scientists say, seems to improve meditators’ ability to control their emotions even when they’re not meditating. It seems to give meditators more emotional ballast, making them less easily swept up in the ups and downs of the present.” – Joseph Stromberg

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Lusnig, L., Radach, R., Mueller, C. J., & Hofmann, M. J. (2020). Zen meditation neutralizes emotional evaluation, but not implicit affective processing of words. PloS one, 15(2), e0229310. https://doi.org/10.1371/journal.pone.0229310

 

Abstract

There is ample evidence that meditation can regulate emotions. It is questionable, however, whether meditation can down-regulate sensitivity to emotional experience in high-level cognitive representations such as words. The present study shows that adept Zen meditators rated the emotional valence of (low-arousal) positive and (high- and low-arousal) negative nouns significantly more neutral after a meditation session, while there was no change of valence ratings after a comparison intervention in the comparison group. Because the Zen group provided greater “openness to experience” and lower „need for achievement and performance” in the “Big Five” personality assessment, we used these scores as covariates for all analyses. We found no differential emotion effects of Zen meditation during lexical decision, but we replicated the slow-down of low-arousal negative words during lexical decision in both groups. Interestingly, Zen meditation elicited a global facilitation of all response times, which we discuss in terms of increased attentional resources after meditation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029852/

 

Improve Parkinson’s Disease Symptoms with Tai Chi

Improve Parkinson’s Disease Symptoms with Tai Chi

 

By John M. de Castro, Ph.D.

 

tai chi can be used as an add-on to current physical therapies and medications to ease some of the key problems faced by people with Parkinson’s disease.” – Peter Wayne

 

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

 

Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications which can reduce life expectancy, such as falls, choking, and cardiovascular problems. Parkinson’s Disease (PD) also has psychological effects, especially cognitive decline, anxiety, and depression. All of these symptoms result in a marked reduction in the quality of life.

 

There are no cures for Parkinson’s Disease or even treatments to slow its progression. There are only treatments that can produce symptomatic relief. So, there is a need to discover new and different treatments. Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients.  In addition, Tai Chi practice has been shown to improve the symptoms of Parkinson’s Disease. Hence, Tai Chi  may be an excellent treatment for the symptoms of Parkinson’s Disease.

 

In today’s Research News article “Tai Chi versus routine exercise in patients with early- or mild-stage Parkinson’s disease: a retrospective cohort analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013627/), Li and colleagues recruited adult patients with Parkinson’s Disease and randomly assigned them to receive either 90 minutes, 3 times per week for two months of routine exercise or of a 6-move Yang Tai Chi practice. They were measured before and after training for walking speed, up-and-go from chair, functional reach, functional activities, and falls over 6-month periods.

 

They found that both the exercise and Tai Chi practices produced significant improvements in walking speed, up-and-go from chair, and functional reach and significantly decreased numbers of falls over the 6-month period following treatment. But the Tai Chi group had superior outcomes compared to routine exercise.  In addition, a greater number of Tai Chi participants were able to withdraw from medication or reduce medication doses. No adverse events were recorded.

 

The results suggest that both exercise and Tai Chi practices produce significant improvements in the motor symptoms of Parkinson’s Disease but Tai Chi practice produces even greater improvements. The reduction in falls observed in the Tai Chi group are particularly important as falls are a significant contributor to injuries and mortality in Parkinson’s Disease patients.

 

It’s important to note that Tai Chi is a gentle and safe mindfulness practice. It is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It is inexpensive to administer, can be performed in groups or alone, at home or in a facility, and can be quickly learned. In addition, it can be practiced in social groups. This can make it fun, improving the likelihood of long-term engagement in the practice. Hence, Tai Chi practice would appear to be a superior practice to be added to routine treatment for the improvements of the symptoms of Parkinson’s Disease.

 

So, improve Parkinson’s Disease symptoms with Tai Chi.

 

Daily Tai Chi practice is extremely helpful to those with chronic ailments and illnesses like cancer, heart disease, stroke, Parkinson’s, Alzheimer’s, osteoporosis, peripheral neuropathy, respiratory problems and irritable bowel syndrome to name a few,”  – Mwezo Kujiweza

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Li, Q., Liu, J., Dai, F., & Dai, F. (2020). Tai Chi versus routine exercise in patients with early- or mild-stage Parkinson’s disease: a retrospective cohort analysis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 53(2), e9171. https://doi.org/10.1590/1414-431X20199171

 

Abstract

Parkinson’s disease cannot be cured but symptoms can be improved by making use of physical therapy. The objective of the study was to compare the effect of routine exercises and Tai Chi on physical and clinical performance in elderly people suffering from Parkinson’s disease. Data from interviews, physical and clinical performance, and levodopa consumption of 500 patients with confirmed Parkinson’s disease (severity level I to III) were collected and analyzed. Participants who received 80 min/day Tai Chi 3 times/week for 2 months were included in the Tai Chi (TC) group (n=250) and those who received 90 min/day routine exercise 3 times/week for 2 months were included in routine exercise (RE) group (n=250). Timed up-and-go, 50-foot speed walk, and functional reach were improved by Tai Chi and routine exercise (P<0.05 for all) but intensities of Tai Chi for improvement of such parameters was higher than routine exercise. Incidence of falls was decreased by both physical therapies (P<0.05 for all) but more for the TC group (P<0.0001, q=38.512). In the TC group, at the end of follow-up, 22 (9%) patients were successful in withdrawal of levodopa treatment. Also, the dose of levodopa was decreased in patients of the TC group who had to continue levodopa. Tai Chi had the potential to slow down the progression of symptoms of Parkinson’s disease and delayed the introduction of levodopa (level of evidence: III).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013627/

 

Improve Autonomic Nervous System Function with Yogic Breathing

Improve Autonomic Nervous System Function with Yogic Breathing

 

By John M. de Castro, Ph.D.

 

The Bhramari pranayama breathing practice . . . .. is beneficial and instantly calming down the mind. It is one of the best breathing exercises to free the mind of distress, anxiety, or frustration and get rid of anger to a great level.” – Alpesh Jain

 

Breathing is essential for life and generally occurs automatically. It’s easy to take for granted as it’s been there our entire lives. Nevertheless, we become more aware of it when it varies with circumstances, such as when we exercise and also in emotional states, especially fear and anxiety. But we rarely notice it during everyday ongoing life. Yet, its characteristics are associated with our state of well-being. Slow deep breathing is characteristic of a healthy relaxed state. Breathing exercises are common in yoga practices and have been found to have a number of beneficial effects. Bhramari pranayama (Bee breathing) is a yogic breathing practice that adopts simple regulation of voluntary breathing involving an exhalation that simulates the typical humming sound of a bee.

 

Adolescence is a time of mental, physical, social, and emotional growth. It is during this time that higher levels of thinking, sometimes called executive function, develops. But adolescence can be a difficult time, fraught with challenges. During this time the child transitions to young adulthood; including the development of intellectual, psychological, physical, and social abilities and characteristics. There are so many changes occurring during this time that the child can feel overwhelmed and unable to cope with all that is required. It is not known whether training in Bhramari pranayama can be beneficial for adolescents.

 

In today’s Research News article “Effects of yoga breathing practice on heart rate variability in healthy adolescents: a randomized controlled trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997567/), Kuppusamy and colleagues recruited healthy adolescents, 13-18 years of age, and randomly assigned them to either Bhramari pranayama (Bee breathing) or no treatment. Yogic breathing was practiced in the morning for 30 minutes, 5 days per week for 6 months. The participants electrocardiogram (ECG) was measured at rest before and after training.

 

With the ECG they found that in comparison to baseline and the no-treatment control participants, the adolescents who practiced yogic breathing had significantly lower heart rates and significantly higher time and frequency domains of heart rate variability. Increased heart rate variability indicates greater activity of the parasympathetic division of the autonomic nervous system that is active during relaxation. Hence, the findings suggest that practicing yogic breathing improves autonomic function.

 

Increased heart rate variability is associated with lower stress and greater health and longevity and psychological well-being. Hence, increased heart rate variability in the adolescents who practiced Bhramari pranayama (Bee breathing) is an indicator of improved autonomic function that underlies greater health and well-being. This suggests that practicing yogic breathing would improve the youth’s ability to develop healthily during the turbulent times of the teen years.

 

So, improve autonomic nervous system function with yogic breathing.

 

The noise of bhramari’s buzzing can drown out the endless mental tape loops that can fuel emotional suffering, making it a useful starting point for those whose minds are too “busy” to meditate.” – Timothy McCall

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kuppusamy, M., Kamaldeen, D., Pitani, R., Amaldas, J., Ramasamy, P., Shanmugam, P., & Vijayakumar, V. (2020). Effects of yoga breathing practice on heart rate variability in healthy adolescents: a randomized controlled trial. Integrative medicine research, 9(1), 28–32. https://doi.org/10.1016/j.imr.2020.01.006

 

Abstract

Background

This study was conducted among healthy adolescents to assess the effects of a yoga breathing practice (Bhramari pranayama, Bhr.P) towards cardiac autonomic function using heart rate variability (HRV) parameters.

Methods

Of the 730 eligible subjects screened, 520 healthy adolescents who met the inclusion and exclusion criteria were randomly assigned to either yoga breathing group (n = 260) or control group (n = 260). The yoga breathing group practiced Bhr.P. five days a week for a duration of six months while the control group continued with their daily routine without any intervention. Outcome measures were time and frequency domain of HRV in both groups which were assessed before and after the intervention using Lead II ECG. Linear models were used in the analysis of short term HRV.

Results

After 6 months of yoga breathing, the time domain parameters of short term HRV showed significant (P < 0.05) improvement towards the parasympathetic domain. Frequency domain parameters also showed the same direction of changes. In contrast, control group subjects showed a trend towards a sympathetic domain.

Conclusion

The present study showed a positive shift in cardiac autonomic modulation towards parasympathetic predominance after 6 months of yoga breathing practice among apparently healthy adolescents.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997567/

 

Content Free Awareness is Associated with Increased Brain Attentional Activity and Decreased Self-Awareness Activity

Content Free Awareness is Associated with Increased Brain Attentional Activity and Decreased Self-Awareness Activity

 

By John M. de Castro, Ph.D.

 

“While scientists do not yet fully understand the true origin of consciousness, many agree that it can be measured within the brainwave patterns of the individual.” – EOC Institute

 

In meditation there occurs a number of different states of consciousness. One of the highest levels achieved is content free awareness. In this state there is nothing that the meditator is aware of other than awareness. The meditator is aware and aware of being aware, but nothing else. Changes in awareness are associated with changes in the activity of the brain which can be seen in the Electroencephalogram (EEG) and also in functional Magnetic Resonance Imaging (fMRI). But content free awareness is elusive and what activity in the brain accompanies it is unknown.

 

In today’s Research News article “Content-Free Awareness: EEG-fcMRI Correlates of Consciousness as Such in an Expert Meditator.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2019.03064/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1254058_69_Psycho_20200225_arts_A), Winter and colleagues recruited an meditator with 40 years of experience and over 50,000 hours of formal meditation practice. They simultaneously recorded heart rate, respiration, and brain activity with an electroencephalogram (EEG) and functional Magnetic Resonance Imaging (fMRI) during rest, attention to external stimuli, attention to internal stimuli including memories, and during meditation in a state of content-minimized awareness. After the content free awareness “he reported that he had no awareness of any mental content or any sensory event, including the noise of the MRI scanner. Similarly, he reported having had no experience of self, time, or space of any kind whatsoever at this stage.”

 

They found that heart rate and respiration decreased over the various states reaching its lowest levels during content free awareness. They found that there was a sharp decrease in EEG alpha rhythm power and increase in theta rhythm power during content free awareness. Finally, they found a decrease in functional connectivity in the posterior default mode network and increase in the dorsal attention network during content free awareness.

 

These are interesting results but it must be kept in mind that this was from a single adept expert meditator. Nevertheless, they provide a glimpse at the state of the nervous system during the deepest mental state occurring during meditation. The default mode network is involved in mind wandering, daydreaming, and self-referential thought. The fact that the connectivity within this system was markedly reduced during content free awareness suggests that non-specific mental activity and the idea of self are greatly reduced if not eliminated. The fact that connectivity within the dorsal attentional network increased while there was no increase in the sensory areas of the brain suggests that during content free awareness there was a focused attention that was decoupled from sensory experience. Hence, the brain activity observed in this meditator markedly corresponds to the mental state achieved.

 

So, content free awareness is associated with increased brain attentional activity and decreased self-awareness activity.

 

“The higher state of consciousness is somewhere in between the waking, sleeping and dreaming states. Here, we know we “are” but we don’t know “where” we are. This knowledge that I “am,” but I don’t know “where” I am or “what” I am, is called Shiva.” – Ravi Shankar

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Winter U, LeVan P, Borghardt TL, Akin B, Wittmann M, Leyens Y and Schmidt S (2020) Content-Free Awareness: EEG-fcMRI Correlates of Consciousness as Such in an Expert Meditator. Front. Psychol. 10:3064. doi: 10.3389/fpsyg.2019.03064

 

The minimal neural correlate of the conscious state, regardless of the neural activity correlated with the ever-changing contents of experience, has still not been identified. Different attempts have been made, mainly by comparing the normal waking state to seemingly unconscious states, such as deep sleep or general anesthesia. A more direct approach would be the neuroscientific investigation of conscious states that are experienced as free of any specific phenomenal content. Here we present serendipitous data on content-free awareness (CFA) during an EEG-fMRI assessment reported by an extraordinarily qualified meditator with over 50,000 h of practice. We focused on two specific cortical networks related to external and internal awareness, i.e., the dorsal attention network (DAN) and the default mode network (DMN), to explore the neural correlates of this experience. The combination of high-resolution EEG and ultrafast fMRI enabled us to analyze the dynamic aspects of fMRI connectivity informed by EEG power analysis. The neural correlates of CFA were characterized by a sharp decrease in alpha power and an increase in theta power as well as increases in functional connectivity in the DAN and decreases in the posterior DMN. We interpret these findings as correlates of a top-down-initiated attentional state excluding external sensory stimuli and internal mentation from conscious experience. We conclude that the investigation of states of CFA could provide valuable input for new methodological and conceptual approaches in the search for the minimal neural correlate of consciousness.

https://www.frontiersin.org/articles/10.3389/fpsyg.2019.03064/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1254058_69_Psycho_20200225_arts_A