Improve Neuropsychological Disorders with Yoga

Improve Neuropsychological Disorders with Yoga

 

By John M. de Castro, Ph.D.

 

“yoga might be considered as an effective adjuvant for the patients with various neurological disorders including stroke, Parkinson’s disease, multiple sclerosis, epilepsy, Alzheimer’s disease, dementia, headache, myelopathy, neuropathies.” – A.Mooventhan

 

Mindfulness training and yoga practices have been shown to improve health and well-being in healthy individuals. They have also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. There has accumulated a large amount of research on the effectiveness of yoga practice for the treatment of a variety of physical and mental issues. Hence, it would be useful to summarize what has been learned.

 

In today’s Research News article “Therapeutic role of yoga in neuropsychological disorders.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546763/ ) Nourollahimoghadam and colleagues review and summarize the published research regarding the effectiveness of yoga practice for the treatment of a variety of neuropsychological disorders.

 

They report that the published research found that yoga practice produced significant improvements in physical illnesses including migraine headaches, Alzheimer’s Disease, epilepsy, multiple sclerosis, Parkinson’s Disease, and neuropathy. Yoga practice also produced significant improvements in psychological well-being including anxiety, stress, depression, bipolar disorder, schizophrenia, somatoform disorders, obsessive-compulsive disorder, and burnout. They further report that yoga may produce its beneficial effects by altering the chemistry, electrical activity, structures, and connectivity within the brain.

 

Hence Yoga practice appears to have a myriad of positive physical and psychological benefits. The authors, however, point to weaknesses in the research including small sample sizes, short-term follow-up, confounding variables, and lack of appropriate controls. So, more and better controlled studies are needed to verify the benefits of yoga practice. Hence, the present state of knowledge supports the engagement in yoga practice to advance the physical and mental well-being of both ill and healthy individuals.

 

So, improve neuropsychological disorders with yoga.

 

Yoga can be a helpful practice of self-care for people with multiple sclerosis (MS) and other neurological conditions (such as stroke, traumatic brain injury, Parkinson’s disease, Lyme’s disease, Lou Gehrig’s disease).” – Mary Hilliker

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on on Twitter @MindfulResearch

 

Study Summary

 

Nourollahimoghadam, E., Gorji, S., Gorji, A., & Khaleghi Ghadiri, M. (2021). Therapeutic role of yoga in neuropsychological disorders. World journal of psychiatry, 11(10), 754–773. https://doi.org/10.5498/wjp.v11.i10.754

 

Abstract

Yoga is considered a widely-used approach for health conservation and can be adopted as a treatment modality for a plethora of medical conditions, including neurological and psychological disorders. Hence, we reviewed relevant articles entailing various neurological and psychological disorders and gathered data on how yoga exerts positive impacts on patients with a diverse range of disorders, including its modulatory effects on brain bioelectrical activities, neurotransmitters, and synaptic plasticity. The role of yoga practice as an element of the treatment of several neuropsychological diseases was evaluated based on these findings.

Core Tip: A multitude of beneficial effects of yoga practice and the underlying mechanisms of action have been reported and point out its role as an influential element in the integrative therapy of various neuropsychological disorders. In the planning of further investigations, studies should be designed to achieve more accuracy and precision in the heterogeneous field of yoga practices and potential fields of application.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546763/

 

Reduce Fatigue and Depression in Patients with Multiple Sclerosis with Mindfulness

Reduce Fatigue and Depression in Patients with Multiple Sclerosis with Mindfulness

 

By John M. de Castro, Ph.D.

 

the pragmatic resiliency skills of mindfulness training may be beneficial in helping to mitigate unpleasant and unpredictable mental and physical symptoms that are associated with an MS diagnosis.” – Rachel M. Gilbertson

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years. Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms. But MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis.

 

In today’s Research News article “Mindfulness training during brief periods of hospitalization in multiple sclerosis (MS): beneficial alterations in fatigue and the mediating role of depression.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499486/ ) Sauder and colleagues recruited patients diagnosed with Multiple Sclerosis (MS) who also had symptoms of fatigue and depression during a brief (>5-day) hospital stay. During their hospital stay the patients were administered daily 45-minute mindfulness training based upon Mindfulness-Based Cognitive Therapy (MBCT). They were measured before and after the hospital stay for depression, fatigue, rumination, mindfulness, cognition, and attention.

 

They found that in comparison to baseline after training there were significant increases in mindfulness and distraction techniques to cope with a negative mood and significant decreases in depression, general fatigue, and physical fatigue. Further, they found that the greater the increases in mindfulness the greater the reductions in fatigue and depression. A mediation analysis revealed that mindfulness decreased fatigue indirectly by reducing depression that in turn reduced fatigue.

 

The study lacked a control, comparison, condition and as such caution must be exercised in interpreting the results. But mindfulness has been previously demonstrated in controlled studies to reduce fatigue and depression in a wide variety of people. So, the effects of mindfulness reported here were probably due to mindfulness causing the improvements. What is new here is that mindfulness reduces depression and in turn fatigue in patients with Multiple Sclerosis (MS). The patients also had a significant increase in the coping strategy of using distraction during negative mood states. This suggests that mindfulness training helps them to learn to distract themselves from depression and this may be the mechanism whereby mindfulness reduces depression.

 

Depression and fatigue greatly reduce the patients’ ability to conduct their lives, reducing their quality of life, So, improving depression and fatigue can be very beneficial to these patients. This suggests that mindfulness training should be recommended for patients with Multiple Sclerosis (MS).

 

So, reduce fatigue and depression in patients with multiple sclerosis with mindfulness.

 

Mindfulness practice appears to be a safe, drug-free approach to coping with stress and anxiety, which may in turn help reduce your MS symptoms.” – Amit Sood

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Sauder, T., Hansen, S., Bauswein, C., Müller, R., Jaruszowic, S., Keune, J., Schenk, T., Oschmann, P., & Keune, P. M. (2021). Mindfulness training during brief periods of hospitalization in multiple sclerosis (MS): beneficial alterations in fatigue and the mediating role of depression. BMC neurology, 21(1), 390. https://doi.org/10.1186/s12883-021-02390-7

 

Abstract

Objectives

Persons with MS (PwMS) are frequently affected by fatigue and depression. Mindfulness-based interventions may reduce these symptoms in PwMS and consequently their application has been extended to various settings. Only few efforts have been made to explore effects of short-term mindfulness training during brief periods of hospitalization. In the current study, the feasibility and potential effects of short-term mindfulness training on depression, fatigue, rumination and cognition were explored in PwMS in an acute-care hospital setting. Based on previous work, it was further examined whether the relation between trait mindfulness and fatigue prior to and following the intervention was mediated by depression and whether a mediation effect was also observable throughout the intervention.

Methods

A short-term mindfulness training protocol was developed, tailored to the requirements of the acute-care setting. Subsequently, 30 PwMS were recruited sequentially and received mindfulness training during the routine clinical process (median duration in hospital: eight days, number of sessions: four). Participants completed relevant self-report measures (depression, fatigue, rumination) and a neuropsychological assessment before and after training.

Results

Participants reported significantly increased trait mindfulness and decreased depression and fatigue following the intervention. Respective change scores were highly correlated so that increased trait mindfulness was associated with decreased symptoms. In the rumination domain, patients reported a tendency for an increased adaptive ability to engage in distractive behavior during arising negative mood. Other measures of trait rumination and cognition remained relatively stable. Results of the mediation analyses indicated that depression mediated the negative relationship between trait mindfulness and fatigue symptoms at pre and post assessments. With regards to the change scores, an association between mindfulness and cognitive fatigue ceased to be significant when depression was controlled, albeit in this case, the mediation effect did not reach significance.

Conclusion

Results of the current study indicate that short-term mindfulness training during brief periods of hospitalization may be beneficial for PwMS. They further complement previous work by identifying depression as a potential mediator of the antagonistic relationship between mindfulness and fatigue. Based on the current exploratory study, future trials are warranted to address this mechanism of mindfulness training in more detail.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499486/

 

Mindfulness is Associated with Reduced Depression and Fatigue in Patients with Multiple Sclerosis

Mindfulness is Associated with Reduced Depression and Fatigue in Patients with Multiple Sclerosis

 

By John M. de Castro, Ph.D.

 

Mindfulness can help people with MS learn to distinguish between actual physical discomfort and the stories they tell themselves about the pain (like “I’ll never feel better). Mindfulness can also help improve the anxiety and depression people with the disease may experience.” – Meryl Davids Landau

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.

 

Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms. But MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis.

 

In today’s Research News article “Trait mindfulness is primarily associated with depression and not with fatigue in multiple sclerosis (MS): implications for mindfulness-based interventions.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962308/ ) Sauder and colleagues recruited adult patients diagnosed with multiple sclerosis and had them complete measures of depression, fatigue, and mindfulness.

 

They found that the higher the reported levels of mindfulness, the lower the levels of depression, physical fatigue, and cognitive fatigue. A mediation analysis indicated that depression entirely mediated the relationship between mindfulness and fatigue such that mindfulness was associated with depression and depression was in turn associated with both cognitive and physical fatigue. So, the entire relationship between mindfulness and fatigue resulted from the relationship of mindfulness with depression.

 

These results are correlational and as such causation cannot be determined. Previous research, however, has demonstrated that mindfulness reduces depression and fatigue. So, the current relationships are likely due to causal relationships. Hence, mindful patients with multiple sclerosis are less depressed and this makes them less fatigued. The reason that these patients experience fatigue appears to be due to their depression and mindfulness reduces this depression. This suggests that mindfulness training may be useful in improving the psychological well-being of patients with multiple sclerosis.

 

So, mindfulness is associated with reduced depression and fatigue in patients with Multiple Sclerosis.

 

One of the reasons that mindfulness training is so promising is because it is an easily accessible treatment for all patients. Anyone can use mindfulness — even individuals with limited mobility, who often find other training techniques, like exercise training, to be more challenging,” – Science Daily

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Sauder, T., Keune, P. M., Müller, R., Schenk, T., Oschmann, P., & Hansen, S. (2021). Trait mindfulness is primarily associated with depression and not with fatigue in multiple sclerosis (MS): implications for mindfulness-based interventions. BMC neurology, 21(1), 115. https://doi.org/10.1186/s12883-021-02120-z

 

Abstract

Objectives

Persons with MS (PwMS) often display symptoms of depression and fatigue. Mindfulness-based interventions are known to counteract these symptoms. However, to-date the exact relations between trait mindfulness, depression and fatigue remain to be examined. Fatigue is generally regarded as a symptom immanent to the disease and as a direct neurobiological consequence of increased cytokine levels and cortical atrophy. In depression on the other hand, psychosocial factors in the context of adaptation difficulties are probably of higher relevance. Hence, one may argue that mindfulness, as a trait that promotes successful adaption, may show a strong negative association with depression and a relatively minor negative association with fatigue in PwMS.

Methods

In the current study, the association between self-reported trait mindfulness, fatigue and depression was examined in a sample of 69 PwMS.

Results

Trait mindfulness showed highly significant negative correlations with both, depression and fatigue. Mediation analyses however, revealed that depression mediated the relation between mindfulness and fatigue.

Conclusion

It may be concluded that in PwMS, trait mindfulness shows a genuine negative association with depression, but that it is only secondarily associated with fatigue. Implications for mindfulness-based interventions in MS are discussed. Based on the results of the current study, it may be feasible to promote the acceptance of default fatigue symptoms, instead of an actual reduction of fatigue symptoms.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962308/

 

Movement-Based Therapies are Affective for Rehabilitation from Disease

Movement-Based Therapies are Affective for Rehabilitation from Disease

 

By John M. de Castro, Ph.D.

 

Tai chi is often described as “meditation in motion,” but it might well be called “medication in motion.” There is growing evidence that this mind-body practice, which originated in China as a martial art, has value in treating or preventing many health problems.” – Havard Health

 

Mindful movement practices such as yoga and Tai Chi and Qigong have been used for centuries to improve the physical and mental health and well-being of practitioners. But only recently has the effects of these practices come under scientific scrutiny. This research has been accumulating. So, it makes sense to pause and examine what has been learned about the effectiveness of these practice for rehabilitation from disease.

 

In today’s Research News article “Movement-Based Therapies in Rehabilitation.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476461/ ) Phuphanich and colleagues review and summarize the published research studies of the effects of mindful movement practices on rehabilitation from disease.

 

They report that published research has found that yoga practice reduces fatigue, sleep disturbances, depression, and anxiety and improves the immune system in cancer patients. Yoga has been found to be an effective treatment for mental health issues such as anxiety, depression, and post-traumatic stress disorder (PTSD). Yoga has been found to reduce pain levels, fear avoidance, stress, and sleep disturbance and increases self-efficacy and quality of life in chronic pain patients. Yoga has been found to improve the symptoms of traumatic brain injury, stroke, spinal cord injury, Parkinson disease, dementia, multiple sclerosis, epilepsy, and neuropathies. In addition, yoga has been found to improve systolic and diastolic blood pressures, heart rate, respiratory rate, waist circumference, waist/hip ratio, cholesterol, triglycerides, hemoglobin A1c, and insulin resistance in cardiopulmonary diseases.

 

They report that the published research has found that Tai Chi and Qigong practices reduce falls in the elderly. Tai Chi and Qigong has been found to reduce pain levels and increase quality of life in chronic pain patients. In addition, there is evidence that Tai Chi and Qigong practices improves depression, anxiety, posttraumatic stress disorder, sleep disturbance, schizophrenia, rheumatoid arthritis, spinal cord injury, traumatic brain injury, and immune disorders.

 

These are remarkable findings. The range of disorders that are positively affected by yoga, Tai Chi, and Qigong practices is breathtaking. These practices are also safe and can be widely implemented at relatively low cost and can be performed alone or in groups and at home or in a therapeutic setting. This suggests that these practices should be routinely implemented for rehabilitation from disease.

 

So,  movement-based therapies are affective for rehabilitation from disease.

 

Being mindful through any physical activity can not only improve performance in the activity such as yoga, tennis, swimming, etc, but it can also increase flexibility, confidence in movement and generate a sense of body and mind connection that has the potential for improving your overall sense of well-being.“- Anupama Kommu

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Phuphanich, M. E., Droessler, J., Altman, L., & Eapen, B. C. (2020). Movement-Based Therapies in Rehabilitation. Physical medicine and rehabilitation clinics of North America, 31(4), 577–591. https://doi.org/10.1016/j.pmr.2020.07.002

 

Abstract

Movement therapy refers to a broad range of Eastern and Western mindful movement-based practices used to treat the mind, body, and spirit concurrently. Forms of movement practice are universal across human culture and exist in ancient history. Research demonstrates forms of movement therapy, such as dance, existed in the common ancestor shared by humans and chimpanzees, approximately 6 million years ago. Movement-based therapies innately promote health and wellness by encouraging proactive participation in one’s own health, creating community support and accountability, and so building a foundation for successful, permanent, positive change.

Key Points – Movement-based therapies

  • Decrease fear avoidance and empower individuals to take a proactive role in their own health and wellness.
  • Can benefit patients of any ability; practices are customizable to the individual’s needs and health.
  • Are safe, cost-effective, and potent adjunct treatments used to supplement (not replace) standard care.
  • Deliver patient-centered, integrative care that accounts for the physical, psychological, social, and spiritual aspects of health and illness.
  • Have diverse, evidence-based benefits, including reduction in pain, stress, and debility, and improvements in range of motion, strength, balance, coordination, cardiovascular health, physical fitness, mood, and cognition.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476461/

 

Improve the Quality of Life of Multiple Sclerosis Patients with Mindfulness

Improve the Quality of Life of Multiple Sclerosis Patients with Mindfulness

 

By John M. de Castro, Ph.D.

 

mindfulness can improve quality of life and help people cope better with their MS. Various studies found that mindfulness decreased pain, stress, anxiety and depression.” – MS Trust

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis.  Mindfulness-Based Stress Reduction (MBSR) is a mindfulness training program that involves meditation, yoga, body scan, discussion. and daily practice at home.

 

In today’s Research News article “The Effect of Mindfulness-Based Stress Reduction (MBSR) Therapy on Quality of Life in Women with Multiple Sclerosis, Ahvaz, Iran.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942645/), Kolahkaj and colleagues examine the ability of MBSR training to improve the quality of life of women with Multiple Sclerosis (MS). They recruited women with Multiple Sclerosis and randomly assigned them to receive either a 2-hour, once a week, for 8 weeks program of Mindfulness-Based Stress Reduction (MBSR) or treatment as usual. They were measured before and after treatment and 2 months later for quality of life, pain, physical function, and mental and physical health.

 

They found that in comparison to baseline and the treatment as usual group, the patients who received Mindfulness-Based Stress Reduction (MBSR) practice had significantly better general health, physical function, vitality, mental health, physical, social, and emotional quality of life, and bodily pain.

 

These results are quite striking and corroborate previous findings that mindfulness training can significantly improve the mental health and quality of life of patients with Multiple Sclerosis. Future research should include an active comparison condition such as exercise to eliminate potential bias effects. Nevertheless, the results clearly demonstrate that mindfulness training markedly improvove the physical and mental condition of women with Multiple Sclerosis.

 

So, improve the quality of life of Multiple Sclerosis patients with mindfulness.

 

Mindfulness helped them begin to let go of the frustration that they can’t control [the disease],” They were able to accept their MS, reduce their stress, and hopefully, improve the quality of their lives.” – Ed Tobias

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kolahkaj, B., Zargar, F., & Majdinasab, N. (2018). The Effect of Mindfulness-Based Stress Reduction (MBSR) Therapy on Quality of Life in Women with Multiple Sclerosis, Ahvaz, Iran. Journal of caring sciences, 8(4), 213–217. https://doi.org/10.15171/jcs.2019.030

 

Abstract

Introduction: Low quality of life is one of the most common symptoms of Multiple Sclerosis (MS) which can reduce satisfaction with life, as well as increase death ratio and neuro-mental problems. The present study aimed to determine the effect of Mindfulness-Based Stress Reduction (MBSR) therapy on the quality of life in women with Multiple sclerosis in the city of Ahvaz.

Methods: Forty eight patients who had referred to neurologists were selected by convenient sampling and were assigned into two groups (MBSR and control) randomly. The participants of the two groups answered the 36-item quality of life questionnaire. The experimental group was under treatment for 8 sessions while the control group did not receive any psychological treatment. Data were analyzed, using SPSSver.13 software by repeated measures analysis of variance.

Results: In the MBSR group, the mean subscales of QOL had more significant reduction compare to control group. Also the improvement of all subscales of mental and physical QOL continued after two months later in follow up stage.

Conclusion: The findings suggest that MBSR is useful for improving the quality of life in patients with MS.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942645/

 

Improve the Well-Being of Patients with Multiple Sclerosis with Mindfulness

Improve the Well-Being of Patients with Multiple Sclerosis with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Studies in MS have shown that mindfulness can improve quality of life and help people cope better with their MS. Various studies found that mindfulness decreased pain, stress, anxiety and depression. People undergoing mindfulness training also reported better sleep.” – MS Trust

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis. But mindfulness training is complex as there are a wide variety of different programs and practices and it is not known how long the effects of mindfulness training last with MS patients.

 

In today’s Research News article “Longitudinal associations between mindfulness and well-being in people with multiple sclerosis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300715/ ), Pagnini and colleagues recruited adult patients with Multiple Sclerosis (MS) that had been stable for at least 3 months and randomly assigned them to receive an 8-week program of either Mindfulness-Based Stress Reduction (MBSR) or psychoeducation. MBSR consisted of once a week trainings of 2.5 hours, including meditation, body scan, and yoga practices and discussion and home practice. Psychoeducation consisted of “online videos and home exercises that dealt with stress management, relaxation training, sleep hygiene, fatigue, and social relationships.” The participants were measured before and after training and 6 months later for mindfulness, Multiple Sclerosis quality of life, anxiety, depression, fatigue, and sleep quality.

 

They found that MBSR produced significantly higher quality of life at the end of treatment but this was not maintained 6 months later. They did not find any further significant differences between groups but found overall and 6 months after treatment that the higher the patients’ levels of mindfulness the lower the levels of depression, anxiety, fatigue, and sleep problems and the higher the quality of life.

 

The fact that MBSR did not produce superior benefits to psychoeducation is disappointing as previous studies have shown that mindfulness training is effective in relieving the symptoms of Multiple Sclerosis. It has been previously shown with a variety of healthy and ill individuals that mindfulness can improve depression, anxiety, fatigue, and sleep quality. So, the present findings further extend these findings to patients with MS.

 

Living with Multiple Sclerosis can produce lower levels of well-being and quality of life. Since these patients will be spending the rest of their lives with the disease it is important to implement treatments that can improve their well-being and quality of life. Mindfulness appears to be just such treatment.

 

So, improve the well-being of patients with Multiple Sclerosis with mindfulness.

 

I think it’s important that one of the underpinning attitudes of being more mindful is that of non-striving, which is sometimes described as “trying less and being more”; this notion of acceptance can be a useful message for anyone with MS. This disease brings about some inevitable changes to how we live our lives, how we work, how we parent and so on. This particular aspect of mindfulness can help us to reclaim our lives by responding to the here-and-now present moment.” – MS Trust

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Pagnini, F., Cavalera, C., Rovaris, M., Mendozzi, L., Molinari, E., Phillips, D., & Langer, E. (2018). Longitudinal associations between mindfulness and well-being in people with multiple sclerosis. International journal of clinical and health psychology : IJCHP, 19(1), 22-30.

 

Abstract

Background/Objective: Depression, anxiety, fatigue, and sleep problems are typical conditions reported in people with multiple sclerosis (MS), often resulting in a reduction of their quality of life (QOL) and well-being. Mindfulness is a multifaceted and complex construct that has been increasingly explored for its correlated to well-being. Despite preliminary evidence, longitudinal data about the impact of mindfulness on QOL in MS remain limited. In addition, Langerian mindfulness, one of the prominent approaches to mindfulness, is yet unexplored in this field. The study aims to examine the longitudinal relationships between two forms of mindfulness (Langerian and contemplative) and QOL, anxiety, depression, fatigue, and sleep. Method: Within a larger randomized controlled trial of an online mindfulness-based stress reduction intervention, a cohort of 156 people with MS was recruited and assessed for both mindfulness constructs, QOL, anxiety, depression, fatigue, and sleep problems. Assessments were repeated after 2 and after another 6 months. Results: Both mindfulness constructs were highly correlated with all investigated outcomes. Both Langerian and contemplative mindfulness predicted higher QOL, lower anxiety, depression, fatigue, and sleep, over time. Conclusions: In both approaches dispositional mindfulness is a protective factor against depression, anxiety, fatigue, and sleep in people with MS.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300715/

 

Improve the Psychological Well-Being of Patients with Multiple Sclerosis with Meditation

Improve the Psychological Well-Being of Patients with Multiple Sclerosis with Meditation

 

By John M. de Castro, Ph.D.

 

“Meditation has been shown to decrease cortisol levels and improve sleep in both beginning and experienced meditation practitioners. Since stress has been linked to MS relapses, and meditation has been shown to relieve biological markers of stress, it could help slow MS progression by regulating the body’s stress response.” – Maria Joao Almeida

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis. But it is not known what changes in the patients that mindfulness produces that are responsible for the improvements. One possibility is that mindfulness practice may fundamentally alter the enduring personality characteristics of the patients allowing them to better cope with stress and their disease.

 

In today’s Research News article “Effect of Mindfulness Meditation on Personality and Psychological Well-being in Patients with Multiple Sclerosis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991502/ ), Crescentini and colleagues recruited adults with Multiple Sclerosis forming a meditation group and a treat-as-usual control group. Meditation training occurred in 8-weekly 2-hour sessions containing training, 30 minutes of meditation followed by discussion. Patients were also asked to meditate daily for 30 minutes at home. The patients were measured before and after training for the Big 5 personality characteristics of neuroticism, conscientiousness, agreeableness, extraversion, and openness and also for self-directedness, cooperativeness, self-transcendence, anxiety, depression, and mindfulness.

 

They found that following meditation practice but not treatment-as-usual, there were significant increases in mindfulness and self-maturity as reflected by the self-directedness, cooperativeness, and conscientiousness and a significant decrease in anxiety levels. Mindfulness training has been previously routinely shown to reduce anxiety levels. The changes in personality characteristics produced by meditation in multiple sclerosis patients are interesting and have not been previously reported.

 

The changes in the personality characteristics reflect an increased self-maturity in the patients. The increased conscientiousness, self-directedness, cooperativeness suggests that the meditation practice improves the patients’ ability to take control of their situation and feelings. These appear to result from the increases in thoughtfulness, impulse control, goal-directed behaviors, organization, and mindfulness of details. This greater self-maturity would allow them to better cope with their disease. This is important for effectively living with this life-long disease.

 

So, improve the psychological well-being of patients with Multiple Sclerosis with meditation.

 

“Mindfulness practice appears to be a safe, drug-free approach to coping with stress and anxiety, which may in turn help reduce your MS symptoms.” – Amit Sood

“Mindfulness teaches important life lessons aside from helping you manage chronic symptoms. What you learn through meditation is that life is not perfect, but the journey is very interesting. Along the way, you’ll examine the roses and smell the flowers. You’ll look at that rainbow and say, ‘Wow, that’s incredible!’” – Ruth Geller

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Crescentini, C., Matiz, A., Cimenti, M., Pascoli, E., Eleopra, R., & Fabbro, F. (2018). Effect of Mindfulness Meditation on Personality and Psychological Well-being in Patients with Multiple Sclerosis. International Journal of MS Care, 20(3), 101–108. http://doi.org/10.7224/1537-2073.2016-093

 

PRACTICE POINTS

  • Personality changes, a common symptom in patients with MS, are often associated with poor coping and reduced quality of life.
  • We exposed patients with MS to an 8-week mindfulness-oriented meditation course and evaluated the effects on personality traits and anxiety and depression symptoms.
  • Mindfulness-oriented meditation led to changes in personality/character traits reflecting the maturity of the self at the intrapersonal and interpersonal levels and also led to decreases in trait anxiety.

Abstract

Background:

Varied evidence shows that mindfulness-oriented meditation improves individuals’ mental health, positively influencing practitioners’ personality profiles as well. A limited number of studies are beginning to show that this type of meditation may also be a helpful therapeutic option for persons with multiple sclerosis (MS).

Methods:

We evaluated the effects of an 8-week mindfulness-oriented meditation training on the personality profiles, anxiety and depression symptoms, and mindfulness skills of a group of patients with MS. A control group of patients with MS not enrolled in any training was also tested.

Results:

After mindfulness-oriented meditation training, participants in this group (n = 15) showed an increase in character traits reflecting the maturity of the self at the intrapersonal (self-directedness) and interpersonal (cooperativeness) levels. Moreover, increased mindfulness and conscientiousness and decreased trait anxiety were observed in participants after the training.

Conclusions:

These data support the utility for patients with MS of therapeutic interventions based on mindfulness meditation that may lead to enhanced character and self-maturity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991502/

 

Mindful Patients with Multiple Sclerosis Have Less Interference in Living from Pain

Mindful Patients with Multiple Sclerosis Have Less Interference in Living from Pain

 

By John M. de Castro, Ph.D.

 

“Mindfulness practice appears to be a safe, drug-free approach to coping with stress and anxiety, which may in turn help reduce your MS symptoms.” – Amit Sood

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. So, quality of life becomes a major issue. Quality of life with MS is affected by fatigue, cognitive decrements, physical impairment, depression, and poor sleep quality. For most MS patients pain accompanies the disease and in about a third of patients the pain is clinically significant. There is a thus a critical need for safe and effective methods to help relieve pain in MS sufferers. Mindfulness practices have been shown to relieve pain from a number of different conditions and also to improve the symptoms of multiple sclerosis. It has yet to be demonstrated that mindfulness can reduce the pain in MS patients.

 

In today’s Research News article “Association Between Pain and Mindfulness in Multiple Sclerosis: A Cross-sectional Survey.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825983/ ), Senders and colleagues examine the relationship between the mindfulness of patients with Multiple Sclerosis (MS) and the interference of the pain with daily activities (pain interference). They recruited adult MS patients with average age of 50 years. They measured them for the degree to which pain interfered with their everyday lives and also their levels of mindfulness.

 

They found that there was a highly significant negative relationship between the MS patients’ levels of pain interference and levels of mindfulness such that patients with high levels of mindfulness tended to have low levels of pain interference and patients with low levels of mindfulness tended to have high levels of pain interference. It should be noted that this finding is correlative and causation cannot be concluded. But in previous research mindfulness training has been shown to cause pain reduction in other disorders. This makes it highly likely that mindfulness reduced the pain interference for MS patients.

 

Mindfulness involves an appreciation of the sensations and feelings in the present moment without judging them. This appears to be important to reduce the tendency to magnify the pain by reacting negatively to it and allows the patient to function effectively even with pain. It remains to be shown that training mindfulness in MS patients will reduce their suffering and its interference with everyday living.

 

“Living with the pain, discomfort, and the uncertainties of MS can lead to feelings of frustration, anger, anxiety, and depression. . . By becoming mindful and aware of our thoughts, feelings, and body sensations, we can better control situations, and we have more choices. It also means that we are less likely to end up striving for too long toward goals that it might be wiser to let go. Mindful awareness helps us to become fully conscious of the world as it is, rather than how we wish it could be.” – Regina Boyle Wheeler

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Senders, A., Borgatti, A., Hanes, D., & Shinto, L. (2018). Association Between Pain and Mindfulness in Multiple Sclerosis: A Cross-sectional Survey. International Journal of MS Care, 20(1), 28–34. http://doi.org/10.7224/1537-2073.2016-076

 

Abstract

Background:

Chronic pain is a common symptom in people with multiple sclerosis (MS) and often requires a multimodal approach to care. The practice of mindfulness has been shown to decrease the experience of pain in other conditions, yet little is known about the relationship between mindfulness and pain in people with MS. The objective of this study was to evaluate the association between pain interference and trait mindfulness in people with MS.

Methods:

In this cross-sectional survey, 132 people with any type of MS completed the Patient-Reported Outcomes Measurement Information System Pain Interference scale and the Five Facet Mindfulness Questionnaire. Linear regression was used to test the association between pain and mindfulness while adjusting for demographic and MS-related characteristics.

Results:

The relationship between pain and mindfulness was clinically meaningful and highly significant (t = −5.52, P < .0001). For every 18-point increase in mindfulness scores, pain interference scores are expected to decrease by 3.96 (95% CI, −2.52 to −5.40) points (β = −0.22, P < .0001). The adjusted model, including age, type of MS, the interaction between mindfulness and age, and the interaction between mindfulness and MS type, explains 26% of the variability in pain interference scores (R2 = 0.26).

Conclusions:

These results suggest a clinically significant association between mindfulness and pain interference in MS and support further exploration of mindfulness-based interventions in the management of MS-related pain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825983/

 

Improve Multiple Sclerosis’ Psychological Symptoms with Mindfulness

Improve Multiple Sclerosis’ Psychological Symptoms with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Learning a mind-body technique called “mindfulness meditation” seems to help people with multiple sclerosis cope with the depression, fatigue, and anxiety associated with the disease” – WebMD

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. So, quality of life becomes a major issue. Quality of life with MS is affected by fatigue, cognitive decrements, physical impairment, depression, and poor sleep quality. Indeed, clinically significant depression is present in 15% to 47% of MS patients. There is a thus a critical need for safe and effective methods to help relieve the symptoms of MS, reduce depression and improve quality of life. Mindfulness practices have been previously shown to improve depressionsleep qualitycognitive impairmentsemotion regulation, and fatigue. It has also been shown to improve the symptoms of multiple sclerosis.  Yoga is a mindfulness practice that has the added feature of exercising and stretching the muscles.

 

In today’s Research News article “The Effectiveness of a Body-Affective Mindfulness Intervention for Multiple Sclerosis Patients with Depressive Symptoms: A Randomized Controlled Clinical Trial.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2017.02083/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_485496_69_Psycho_20171214_arts_A ), Tesio and colleagues examine the effectiveness of mindfulness training on the symptoms of Multiple Sclerosis (MS).

 

They recruited MS patients and randomly assigned them to receive either mindfulness training or psychoeducation. Mindfulness training consisted of 8 weekly 2.5-hour sessions of a modified Mindfulness-Based Stress Reduction (MBSR) program that included meditation, body scan, and yoga practices. It was modified with Sensorimotor psychotherapy that “emphasizes the use of somatic resources to attain and sustain a mindful disposition and integrates the concept of a stress response with the concept of a “window of tolerance.”  Psychoeducation occurred on a similar schedule and involved education on MS, stretching, and relaxation. Prior to and after the interventions and 6-months later the patients were measured for depression, anxiety, perceived stress, fatigue, illness perception, Functionality with MS, and neuropsychiatric symptoms.

 

They found that both mindfulness and psychoeducation programs produced significant decreases in depression, anxiety, and perceived stress, but the mindfulness treatment was significantly better at reducing depression (52% vs. 23% reductions in depression respectively). In addition, only mindfulness training produced a significant improvement in quality of life in the patients including improvements in contentment and thinking and fatigue. All of these effects were maintained and still significant at the 6-month follow-up, demonstrating that the interventions produced lasting positive effects.

 

These are interesting and important results that suggest the mindfulness training is a safe and effective treatment for the psychological suffering accompanying Multiple Sclerosis (MS), reducing anxiety, perceived stress and especially depression and improving the patients’ quality of life. Importantly, these effects endured for at least a half a year. The fact that the study contained an active control condition (psychoeducation) further strengthens the conclusions. Mindfulness training has been previously shown to reduce anxiety, perceived stress, and depression in a wide variety of healthy and sick individuals. So, it’s effectiveness with MS patients is not a surprise. But, it is important to make sure that any treatment is effective with each specific target group, and this study demonstrates that it is with MS patients.

 

So, improve multiple sclerosis’ psychological symptoms with mindfulness.

 

“MS is an unpredictable disease, People can go for months feeling great and then have an attack that may reduce their ability to work or take care of their family. Mindfulness training can help those with MS better to cope with these changes. Increased mindfulness in daily life may also contribute to a more realistic sense of control, as well as a greater appreciation of positive experiences that continue be part of life.” – Paul Grossman

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Carletto S, Tesio V, Borghi M, Francone D, Scavelli F, Bertino G, Malucchi S, Bertolotto A, Oliva F, Torta R and Ostacoli L (2017) The Effectiveness of a Body-Affective Mindfulness Intervention for Multiple Sclerosis Patients with Depressive Symptoms: A Randomized Controlled Clinical Trial. Front. Psychol. 8:2083. doi: 10.3389/fpsyg.2017.02083

 

Purpose: Mindfulness interventions have been shown to treat depressive symptoms and improve quality of life in patients with several chronic diseases, including multiple sclerosis, but to date most evaluation of the effectiveness of mindfulness interventions in multiple sclerosis have used patients receiving standard care as the control group. Hence we decided to evaluate the effectiveness of a group-based body-affective mindfulness intervention by comparing it with a psycho-educational intervention, by means of a randomized controlled clinical trial. The outcome variables (i.e., depression, anxiety, perceived stress, illness perception, fatigue and quality of life) were evaluated at the end of the interventions (T1) and after a further 6 months (T2).

Methods: Of 90 multiple sclerosis patients with depressive symptoms (Beck Depression Inventory-II score greater than 13) who were randomized, 71 completed the intervention (mindfulness group n = 36; psycho-educational group n = 35). The data were analyzed with GLM repeated-measures ANOVA followed by pairwise comparisons.

Results: Per-protocol analysis revealed a time by group interaction on Beck Depression Inventory-II score, with the mindfulness intervention producing a greater reduction in score than the psycho-educational intervention, both at T1 and at T2. Furthermore, the mindfulness intervention improved patients’ quality of life and illness perception at T1 relative to the baseline and these improvements were maintained at the follow-up assessment (T2). Lastly, both interventions were similarly effective in reducing anxiety and perceived stress; these reductions were maintained at T2. A whole-sample intention-to-treat (ITT) analysis broadly confirmed the effectiveness of the mindfulness intervention.

Conclusion: In conclusion, these results provide methodologically robust evidence that in multiple sclerosis patients with depressive symptoms mindfulness interventions improve symptoms of depression and anxiety and perceived stress, modulate illness representation and enhance quality of life and that the benefits are maintained for at least 6 months.

https://www.frontiersin.org/articles/10.3389/fpsyg.2017.02083/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_485496_69_Psycho_20171214_arts_A

Improve Multiple Sclerosis with Meditation and Yoga

Improve Multiple Sclerosis with Meditation and Yoga

 

By John M. de Castro, Ph.D.

 

“Studies show that for some people with MS, chronic exposure to stress is associated with worsening neurological symptoms and increased brain lesions. Researchers believe that mindfulness may help people better respond to stress by fostering healthier coping strategies. Mindfulness practice appears to be a safe, drug-free approach to coping with stress and anxiety, which may in turn help reduce your MS symptoms.” – Amit Sood

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years.  Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms.

 

Although there is a progressive deterioration, MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. So, quality of life becomes a major issue. Quality of life with MS is affected by fatigue, cognitive decrements, physical impairment, depression, and poor sleep quality. There is a thus a critical need for safe and effective methods to help relieve the symptoms of MS and improve quality of life.

 

Mindfulness practices have been previously shown to improve depressionsleep quality, cognitive impairmentsemotion regulation, and fatigue. It has also been shown to improve the symptoms of multiple sclerosis.  Yoga is a mindfulness practice that has the added feature of exercising and stretching the muscles. It would seem likely that yoga practice might be an ideal treatment for improving the quality of life and lessening symptoms in patients with multiple sclerosis.

 

In today’s Research News article “Mindfulness in Motion for People with Multiple Sclerosis: A Feasibility Study.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649345/, Gilbertson and Klatt examined the combination of meditation and chair yoga practice which in the treatment of multiple sclerosis. They called this program “Mindfulness in Motion.” In a pilot feasibility study, they recruited patients with multiple sclerosis and provided them with 8 weeks of the “Mindfulness in Motion” program. The program met once a week for one hour and participants were expected to practice at home for 20 minutes every day. Participants were measured before and after the 8 weeks of practice for mindfulness, fatigue, anxiety, depression, behavior control, and positive affect, physical functioning, role limitations due to physical problems, bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems, and mental health.

 

They found that compared to baseline after completing the “Mindfulness in Motion” program the participants showed significant improvements in physical functioning, role-physical, vitality, mental health, anxiety, depression, and positive affect and cognitive and psychosocial fatigue and mindfulness including observing, acting with awareness, nonjudgment, and nonreactivity. Hence, after the 8-week “Mindfulness in Motion” program the participants showed marked and significant improvements in the psychological symptoms of multiple sclerosis.

 

It needs to be kept in mind that this study was a pilot feasibility study that did not have an active control condition, so conclusions must be made carefully. But, this is an extremely encouraging first step that suggests that the combination of two practices which individually produce symptom relief, meditation and chair yoga practice, is a particularly effective treatment for the psychological symptoms of multiple sclerosis.

 

So, improve multiple sclerosis with meditation and yoga.

 

“Studies in multiple sclerosis, these have shown that mindfulness can improve quality of life and help people cope better with their MS. The studies also found that it decreased stress, anxiety and depression.” – MS Trust

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Rachel M. Gilbertson, Maryanna D. Klatt. Mindfulness in Motion for People with Multiple Sclerosis: A Feasibility Study. Int J MS Care. 2017 Sep-Oct; 19(5): 225–231. doi: 10.7224/1537-2073.2015-095

 

Abstract

Background:

Mindfulness in Motion is an 8-week mindfulness-based intervention that uses yoga movement, mindfulness meditation, and relaxing music. This study examined the feasibility of using Mindfulness in Motion in people with multiple sclerosis (MS) and the effect of this program on stress, anxiety, depression, fatigue, and quality of life in people with MS.

Methods:

Twenty-two people with MS completed the 8-week mindfulness program as well as assessments 1 week before and after the intervention.

Results:

Pre/post comparison of four self-reported questionnaires—the Mental Health Inventory, 36-item Short Form Health Status Survey, Modified Fatigue Impact Scale, and Five Facet Mindfulness Questionnaire—showed significant improvement in physical functioning, vitality, and mental health. Specifically, improvements were seen in anxiety, depression, and positive affect; cognitive, psychosocial, and overall functioning regarding fatigue; and mindfulness in the areas of observing, acting with awareness, nonjudgment, and nonreactivity.

Conclusions:

Due to the uncertainty in disease progression associated with MS, and the multiplicity of mental and physical symptoms associated with it, programming that addresses anxiety, depression, and fatigue is a key area of future research in MS disease management. Mindfulness in Motion proved to be a feasible program yielding positive results, supporting the need for research to determine the extent to which the program can improve quality-of-life outcomes for people with MS.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649345/