Pain

Improve Knee Pain with Tai Chi

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Tai chi may be as good as physical therapy for arthritis-related knee pain - Harvard Health

By John M. de Castro, Ph.D.

 

In today’s Research News article “The Effectiveness and Safety of Tai Chi on Knee Pain: A Systematic Review and Meta-Analysis” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12249842/) Lee and colleagues reviewed, summarized, and performed a meta-analysis of the published research studies investigating the effectiveness of Tai Chi practice for the relief of knee pain. They report that Tai Chi significantly reduced knee pain but not more so than physical therapy and resistance training.

 

Reduce knee pain with Tai Chi practice.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Lee H, Sung SH, Lee S. The Effectiveness and Safety of Tai Chi on Knee Pain: A Systematic Review and Meta-Analysis. Healthcare (Basel). 2025 Jul 6;13(13):1615. doi: 10.3390/healthcare13131615. PMID: 40648639; PMCID: PMC12249842.

 

Abstract

Background/Objectives: Although Tai Chi has shown potential benefits for managing chronic pain, its clinical effectiveness specifically for knee pain remains inconclusive. Methods: We systematically searched ten electronic databases for randomized controlled trials (RCTs) investigating the effects of Tai Chi on knee pain. Results: This systematic review and meta-analysis included 11 RCTs involving 706 participants; among them, three studies (n = 169) were eligible for meta-analysis. A comprehensive search of ten electronic databases was conducted up to March 2025. The included RCTs were conducted in the United States (n = 5), China (n = 3), South Korea (n = 2), and Turkey (n = 1). Compared to health education, Tai Chi significantly improved knee pain, as measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score (mean difference (MD) = −0.60; 95% CI: −6.52 to −3.28; p < 0.00001) and the Visual Analogue Scale (VAS) (MD = −1.44; 95% CI: −1.95 to −0.93; p < 0.00001). Tai Chi also significantly improved knee function compared to health education (WOMAC function score—MD = −13.49; 95% CI: −17.11 to −9.87; p < 0.00001). Four RCTs comparing Tai Chi with no intervention reported favorable effects on knee pain and function; however, a meta-analysis was not possible due to limited data. In contrast, two studies comparing Tai Chi with active controls, such as physical therapy and resistance training, found no significant differences in pain or functional outcomes. Two studies reported increased knee pain during initial Tai Chi sessions, but no adverse events occurred after postural corrections. Conclusions: While Tai Chi appears promising for knee pain management, further large-scale, high-quality RCTs with rigorous methodology are needed to establish definitive evidence.

 

Decrease Pain and Dysfunction with Chronic Non-Specific Low Back Pain with Qigong Practice

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integrated tai chi and qigong class

By John M. de Castro, Ph.D.

 

In today’s Research News article “Effect of qigong on pain and disability in patients with chronic non-specific low back pain: a systematic review and meta-analysis of randomized controlled trials” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11849339/)  Yu and colleagues reviewed and summarized the published randomized controlled research studies on the effectiveness of Qigong practice for the relief of Chronic non-specific low back pain. They report that the published research found that Qigong practice significantly decreased pain and the degree of dysfunction to a greater extent than control short-term or long-term interventions.

 

Qigong practice improves chronic non-specific low back pain.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Yu D, Wu M, Zhang J, Song W, Zhu L. Effect of qigong on pain and disability in patients with chronic non-specific low back pain: a systematic review and meta-analysis of randomized controlled trials. J Orthop Surg Res. 2025 Feb 24;20(1):194. doi: 10.1186/s13018-025-05576-8. PMID: 39994723; PMCID: PMC11849339.

 

Abstract

Background

Chronic non-specific low back pain (CNLBP) is a common health problem worldwide. Patients with CNLBP often suffer from persistent pain, with a few being disabled by their pain, affecting their daily functioning and social participation. This study aims to systematically evaluate the effects of pain and dysfunction in Qigong patients with chronic non-specific back pain through systematic evaluation and gathered analysis of random control test data.

Methods

We searched nine databases from their inception dates until April 2024. Relevant randomized controlled trials (RCTs) were included. Patients were assessed for pain using the Visual Analog Scale and Numeric Pain Rating Scale and for disability using the Oswestry Disability Index and Roland-Morris disability questionnaire. The risk of bias was assessed using the Cochrane Collaboration tool. CMA V3.0 was used to analyze data.

Results

Sixteen RCTs involving 1175 participants were included. These studies have different designs, and the participants are mainly around 60 years old. The results showed that the qigong practice improved pain significantly more than the control measures ([Mean Difference MD] = − 1.34, 95% confidence intervals [CI] − 1.76 to − 0.92, p < 0.001 Minimal Clinically Important Differences MCID = 1.5), and the efficacy of short-term interventions (MD = − 1.88, 95% CI − 2.87 to − 0.9, p < 0.001) was superior to that of long-term interventions (MD = − 1.07, 95% CI − 1.49 to − 0.65, p < 0.001). For improvement in the degree of dysfunction, qigong practice showed a higher effect size (MD = − 5.88, 95% CI − 7.98 to − 3.78, p < 0.001 MCID = 5) than that observed in the control group.

Conclusion

Qigong practice is effective in improving disability in patients with CNLBP, but has no significant effect on improving pain. However, due to the high heterogeneity, the results need to be interpreted with caution.

 

Qigong practice reduces the disability of chronic back pain patients

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Qigong: What You Need To Know | NCCIH

By John M. de Castro, Ph.D.

 

In today’s Research News article “Effect of qigong on pain and disability in patients with chronic non-specific low back pain: a systematic review and meta-analysis of randomized controlled trials.” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11849339/ ) Yu and colleagues review and summarize the published research on the effects of Qigong practice on the pain and disability of patients with chronic non-specific back pain. They report that the research indicates that Qigong practice produces a significant in the disability of the patients but no significant reduction in pain.

 

So, Qigong practice is beneficial for chronic back pain patients.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Yu D, Wu M, Zhang J, Song W, Zhu L. Effect of qigong on pain and disability in patients with chronic non-specific low back pain: a systematic review and meta-analysis of randomized controlled trials. J Orthop Surg Res. 2025 Feb 24;20(1):194. doi: 10.1186/s13018-025-05576-8. PMID: 39994723; PMCID: PMC11849339.

Abstract

Background

Chronic non-specific low back pain (CNLBP) is a common health problem worldwide. Patients with CNLBP often suffer from persistent pain, with a few being disabled by their pain, affecting their daily functioning and social participation. This study aims to systematically evaluate the effects of pain and dysfunction in Qigong patients with chronic non-specific back pain through systematic evaluation and gathered analysis of random control test data.

Methods

We searched nine databases from their inception dates until April 2024. Relevant randomized controlled trials (RCTs) were included. Patients were assessed for pain using the Visual Analog Scale and Numeric Pain Rating Scale and for disability using the Oswestry Disability Index and Roland-Morris disability questionnaire. The risk of bias was assessed using the Cochrane Collaboration tool. CMA V3.0 was used to analyze data.

Results

Sixteen RCTs involving 1175 participants were included. These studies have different designs, and the participants are mainly around 60 years old. The results showed that the qigong practice improved pain significantly more than the control measures ([Mean Difference MD] = − 1.34, 95% confidence intervals [CI] − 1.76 to − 0.92, p < 0.001 Minimal Clinically Important Differences MCID = 1.5), and the efficacy of short-term interventions (MD = − 1.88, 95% CI − 2.87 to − 0.9, p < 0.001) was superior to that of long-term interventions (MD = − 1.07, 95% CI − 1.49 to − 0.65, p < 0.001). For improvement in the degree of dysfunction, qigong practice showed a higher effect size (MD = − 5.88, 95% CI − 7.98 to − 3.78, p < 0.001 MCID = 5) than that observed in the control group.

Conclusion

Qigong practice is effective in improving disability in patients with CNLBP, but has no significant effect on improving pain. However, due to the high heterogeneity, the results need to be interpreted with caution.

 

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May be an image of 1 person and sleepwearMindfulness Meditation Reduces Pain.

 

By John M. de Castro, Ph.D.

 

In today’s Research News article “Mindfulness Meditation and Placebo Modulate Distinct Multivariate Neural Signatures to Reduce Pain” (See summary below) Riegner and colleagues demonstrate that mindfulness meditation reduces both subjective pain and the brain responses to pain to a greater extent than a placebo.

Hence, mindfulness meditation is an effective treatment for pain.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

Riegner G, Dean J, Wager TD, Zeidan F. Mindfulness Meditation and Placebo Modulate Distinct Multivariate Neural Signatures to Reduce Pain. Biol Psychiatry. 2025 Jan 1;97(1):81-88. doi: 10.1016/j.biopsych.2024.08.023. Epub 2024 Aug 30. PMID: 39216636; PMCID: PMC11608143.

Abstract

Background: Rather than a passive reflection of nociception, pain is shaped by the interplay between one’s experiences, current cognitive-affective states, and expectations. The placebo response, a paradoxical yet reliable phenomenon, is postulated to reduce pain by engaging mechanisms shared with active therapies. It has been assumed that mindfulness meditation, practiced by sustaining nonjudgmental awareness of arising sensory events, merely reflects mechanisms evoked by placebo. Recently, brain-based multivariate pattern analysis has been validated to successfully disentangle nociceptive-specific, negative affective, and placebo-based dimensions of the subjective pain experience.

Methods: To determine whether mindfulness meditation engages distinct brain mechanisms from placebo and sham mindfulness to reduce pain, multivariate pattern analysis pain signatures were applied across 2 randomized clinical trials that employed overlapping psychophysical pain testing procedures (49 °C noxious heat; visual analog pain scales) and distinct functional magnetic resonance imaging techniques (blood oxygen level-dependent; perfusion based). After baseline pain testing, 115 healthy participants were randomized into a 4-session mindfulness meditation (n = 37), placebo-cream conditioning (n = 19), sham mindfulness meditation (n = 20), or book-listening control (n = 39) intervention. After each intervention, noxious heat was administered during functional magnetic resonance imaging and each manipulation.

Results: A double dissociation in the multivariate pattern analysis signatures supporting pain regulation was revealed by mindfulness meditation compared with placebo cream. Mindfulness meditation produced significantly greater reductions in pain intensity and pain unpleasantness ratings and nociceptive-specific and negative affective pain signatures than placebo cream, sham mindfulness meditation, and control interventions. The placebo-cream group significantly lowered the placebo-based signature.

Conclusions: Mindfulness meditation and placebo engaged distinct and granular neural pain signatures to reduce pain.