Meditation

Meditation Alters Gut Microbes for Better Health

psyjdc Leave a comment

Meditation Alters Gut Microbes for Better Health

 

By John M. de Castro, Ph.D.

 

“In calming your stress response, meditation can help prevent the slowed digestion speed, altered gene expression, intestinal permeability, and disruptive changes to gut microbes caused by stress.” – Crystal Star

 

Functional Gastrointestinal Disorders are the most common disorders of the gastrointestinal tract in the general population. The most common disorder in this group is Irritable Bowel Syndrome (IBS). Functional Gastrointestinal Disorders can involve the esophagus, stomach and/or intestines and are disorders of function (how these structures work), not structural or biochemical abnormalities. Estimates vary, but about 25% of people in the United States have one of these disorders. The conditions account for about 40% of GI problems seen by doctors and therapists.

 

The cause(s) of Functional Gastrointestinal Disorders are not known. But emotion dysregulation is suspected to be involved. It is clear that psychological stress exacerbates the illnesses and anxiety amplifies the symptoms. This suggests that mindfulness or the lack thereof may be involved as mindfulness is known to be helpful in reducing the psychological and physical responses to stress and mindfulness is known to improve emotion regulation. In addition, contemplative practice has been shown to improve the symptoms of Irritable Bowel Syndrome.

 

The GI tract contains intestinal micro-organisms, flora, bacteria, that have major effects throughout the body through the bacteria-intestinal-brain axis. This can affect overall health. So, it would make sense to investigate the relationship of meditation practice with intestinal micro-organisms.

 

In today’s Research News article “Long-Term Vegan Meditation Improved Human Gut Microbiota.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358775/ ) Jia and colleagues recruited healthy long-term (over 3 years) vegan meditators and a group of omnivore nonmeditators. The groups were equivalent in gender, age, BMI, and most of the blood biochemical and blood routine indicators. Fecal samples were collected and subjected to 16S rDNA sequencing which measures bacteria present.

 

They found that the two groups were equivalent in fecal microbial diversity. The majority of the bacterial fell into 4 divisions, Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria. Of those divisions the vegan meditators had significantly higher levels of Firmicutes and significantly lower levels of Actinobacteria, and Proteobacteria. They further found that there were 14 bacteria types that distinguished the groups with the vegan meditators having significantly higher levels. These bacteria types are associated with improved immunity, reduced inflammatory responses, changed intestinal endocrine activity, improved colon health, and reduced likelihood of colon cancer.

 

It should be kept in mind that the groups were naturally occurring groups and there was no random assignment. So, the groups might differ for reasons other than meditation and diet. In addition, the groups differed in both meditation and type of diet. It cannot be determined whether meditation or the vegan diet or the combination of both was responsible for the differences in intestinal bacteria. Nevertheless, the results suggest that a vegan diet and meditation may alter the intestinal flora to improve health.

 

So, meditation alters gut microbes for better health.

 

“During stress, an altered gut microbial population affects the regulation of neurotransmitters mediated by the microbiome and gut barrier function. Meditation helps regulate the stress response, thereby suppressing chronic inflammation states and maintaining a healthy gut-barrier function.” – Ayman Mukerji Househam

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Jia, W., Zhen, J., Liu, A., Yuan, J., Wu, X., Zhao, P., Zhao, L., Li, X., Liu, Q., Huang, G., & Xu, A. (2020). Long-Term Vegan Meditation Improved Human Gut Microbiota. Evidence-based complementary and alternative medicine : eCAM, 2020, 9517897. https://doi.org/10.1155/2020/9517897

 

Abstract

Objective

Meditation has been widely used for the treatment of a variety of psychological, cardiovascular, and digestive diseases as well as chronic pain. Vegetarian diets can effectively prevent hypertension, metabolic diseases such as diabetes and obesity, and certain cancers. Meditation and vegetarian diets have been recognized as components of a healthy lifestyle and have therefore attracted more people around the world. Meditation can help regulate overall health through the neural-endocrine-immune network. Changes in dietary habits can affect the composition of the intestinal flora, which in turn affects human physiology, metabolism, nutrition, and immune function through the bacteria-intestine-brain axis. Here, we aimed to investigate the effect of long-term meditation and vegan diet on human intestinal flora.

Materials and Methods

The present study used 16S rDNA sequencing technology to detect the differences in intestinal flora between 12 healthy vegan subjects receiving long-term meditation training and 12 healthy omnivorous subjects who never received any meditation training.

Results

The results showed that, compared with the subjects in the omnivorous healthy control group who had never received any meditation training, the intestinal flora structure in the people who followed the long-term vegan meditation practices changed significantly. The intersection set between the results of the LEfSe analysis and the Wilcoxon rank sum test includes 14 bacterial genera. These 14 genera are defined as the dominant genera, and the AUC value was 0.92 in the ROC curve, which demonstrates that the 14 genera can be used as a biomarker to distinguish the two groups. Three beneficial bacteria genera (Bifidobacterium, Roseburia, and Subdoligranulum) were significantly enriched in the meditation group with a threshold of 4, according to the LDAs. The functional prediction of differentially enriched intestinal flora showed that the metabolism of tyrosine, propionate, niacin, and nicotinamide in the intestinal micro-organisms in the meditation group was significantly reduced compared with those in the control group, while the biosynthesis of flavones, flavone alcohols, butosin, and neomycin; flavonoid-mediated oocyte maturation; cytoskeleton protein pathways; and antigen processing and presentation were significantly enhanced.

Conclusions

These results indicate that long-term vegan meditation plays a positive role in improving the body’s immunity and adjusting endocrine and metabolic levels, enabling the body to be in a state of good health.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358775/

 

Improve Mindfulness and Emotion Regulation with Meditation

psyjdc Leave a comment

Improve Mindfulness and Emotion Regulation with Meditation

 

By John M. de Castro, Ph.D.

 

“By way of mindfulness meditation, individuals can learn how to regulate their emotions in a way that aversive stimuli will be viewed objectively; thus, the person can be free of attachment from said negative feelings.” – Thomas M Jones

 

Mindfulness practice has been shown to improve emotion regulation. Practitioners demonstrate the ability to fully sense and experience emotions, but respond to them in more appropriate and adaptive ways. In other words, mindful people are better able to experience yet control their responses to emotions. This is a very important consequence of mindfulness. Humans are very emotional creatures and these emotions can be very pleasant, providing the spice of life. But when they get extreme, they can produce misery and even mental illness. The ability of mindfulness training to improve emotion regulation is thought to be the basis for a wide variety of benefits that mindfulness provides to mental health and the treatment of mental illness especially depression and anxiety disorders.

 

In today’s Research News article “Short-Term Meditation Training Fosters Mindfulness and Emotion Regulation: A Pilot Study.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2020.558803/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1473550_69_Psycho_20201103_arts_A ) Fazia and colleagues conducted a pilot study in which they recruited healthy college students and provided them with meditation training in 5 1-hour weekly sessions. They were measured before and after training for well-being, problems/symptoms, life functioning, mindfulness, emotion regulation, and spirituality.

 

They found that in comparison to baseline, after meditation training there were significant increases in mindfulness, especially the acting with awareness and non-judging facets, and the cognitive reappraisal facet of emotion regulation. Hence, in this pilot study, meditation training appeared to improve mindfulness and the ability to regulate emotions.

 

This study lacks a comparison, control, condition and as a result is open to a wide variety of confounding influences. So, no definitive conclusions can be reached. But prior research in highly controlled studies have shown repeatedly that meditation training improves mindfulness and emotion regulation. So, the present results likely represent causal effects of meditation on the psychological functioning of the participants.

 

So, improve mindfulness and emotion regulation with meditation.

 

“mindfulness can help patients view their emotions from a more detached perspective. . .This means that patients may be able to think more clearly and generate new strategies to resolve their issues without emotional interference.” – NICABM

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Fazia T, Bubbico F, Iliakis I, Salvato G, Berzuini G, Bruno S and Bernardinelli L (2020) Short-Term Meditation Training Fosters Mindfulness and Emotion Regulation: A Pilot Study. Front. Psychol. 11:558803. doi: 10.3389/fpsyg.2020.558803

 

ABSTRACT

The practice of meditation has been historically linked to beneficial effects, not only in terms of spirituality but also in terms of well-being, general improvement of psychophysiological conditions and quality of life. The present study aims to assess the beneficial effects of a short-term intervention (a combination of 12 practical 1-h sessions of meditation, called Integral Meditation, and lectures on neuroscience of meditation) on psychological indicators of well-being in subjects from the general population. We used a one-group pretest-posttest quasi-experimental design, in which all participants (n = 41, 17 men and 24 women, with a mean age of 41.1 years) underwent the same intervention. Out of these, 24 had already experienced meditation practice, but only 12 in a continuative way. Effects were assessed by the standardized Italian version of three self-report questionnaires: Core Outcome in Routine Evaluation-Outcome Measure (CORE-OM), Five-Facet Mindfulness Questionnaire (FFMQ), and Emotion Regulation Questionnaire (ERQ). The questionnaires were filled in at baseline and immediately after the last meditation session. Linear mixed effect models were used to evaluate pre-post treatment changes on each outcome. Participants showed a general, close to a statistically significant threshold, improvement in the total score of CORE-OM and its different domains. The total score of FFMQ (β = 0.154, p = 0.012) indicates a statistically significant increase in the level of mindfulness as well as in the domains acting with awareness (β = 0.212, p = 0.024), and non-judging of inner experiences (β = 0.384, p < 0.0001). Lastly, we observed a statistically significant improvement in the cognitive reappraisal ERQ domain (β = 0.541, p = 0.0003). Despite some limitations (i.e., small sample size, lack of a randomised control group and sole use of “soft” measurements, such as self-report questionnaires), this study offers promising results regarding the within-subject effectiveness of our intervention that includes a meditation practice on psychological indicators, thus providing interesting preliminary results.

https://www.frontiersin.org/articles/10.3389/fpsyg.2020.558803/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1473550_69_Psycho_20201103_arts_A

 

Unique Brain Activity Registers Internal Attentional States During Meditation

psyjdc Leave a comment

Unique Brain Activity Registers Internal Attentional States During Meditation

 

By John M. de Castro, Ph.D.

 

“Your brain is actually shaped by your thoughts and your behaviors. . . meditation can help boost attention and keep the brain sharp. . .  mindful breath awareness may improve attention and help curb impulsive behavior” – Grace Bullock

 

There has accumulated a large amount of research demonstrating that mindfulness has significant benefits for psychological, physical, and spiritual wellbeing. It even improves high level thinking known as executive function and emotion regulation and compassion. One of the primary effects of mindfulness training is an improvement in the ability to pay attention to the task at hand and ignore interfering stimuli. This is an important consequence of mindfulness training and produces improvements in thinking, reasoning, and creativity. The importance of heightened attentional ability to the individual’s ability to navigate the demands of complex modern life cannot be overstated. It helps in school, at work, in relationships, or simply driving a car. As important as attention is, it’s surprising that little is known about the mechanisms by which mindfulness improves attention.

 

There is evidence that mindfulness training improves attention by altering the brain. It appears That mindfulness training increases the size, connectivity, and activity of areas of the brain that are involved in paying attention. But there are various states of attention including meditation-related states: breath attention, mind wandering, and self-referential processing, and control states e.g. attention to feet and listening to ambient sounds. It is not known what changes occur in the brain during these five different modes and if they can be used to better discriminate the nature of attentional changes during meditation.

 

In today’s Research News article “Focus on the Breath: Brain Decoding Reveals Internal States of Attention During Meditation.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483757/ ) Weng and colleagues recruited healthy adult meditators (at least 5 years of experience) and non-meditators. They were given a series of tasks while having their brains scanned with functional Magnetic Resonance Imaging (fMRI). They were asked for 16-50 seconds to 1) pay attention to their breath, 2) let the mind wander, 3) think about past events, 4) pay attention to their feet, and 5) pay attention to ambient sounds. The 5 conditions were repeated multiple times in random orders. They then performed a 10-minute breath following meditation followed by a repeat of the premeditation tasks. Artificial intelligence was employed to determine unique neural activity associated with each of the 5 mental states for each participant.

 

They found unique individual brain activity patterns for each participant and could reliably distinguish different individual patterns for the 5 mental states. They then used these individualized patterns in an attempt to determine mental state during the breath focused meditation. They found that the individualized patterns identified for following the breath were present a greater percentage of time than the mind wandering or self-referential states when engaging in breath focused meditation. Further they found that the greater the amount of time for each participant in the breath following brain pattern the larger the rating by the participant of their engagement with breath following.

 

This was a proof of concept study. But it successfully demonstrated that unique individual patterns of brain activity can be identified for 5 mental states. These could be reliably differentiated. It also showed that these patterns could be used to identify breath following during breath following meditation. This suggests that this method may be used to identify mental states during ongoing meditation sessions. This could be a powerful research tool for future investigations of the mental states occurring during meditation.

 

So, unique brain activity registers internal attentional states during meditation.

 

“Mindfulness training can help change patterns of brain activity because the synapses within these attentional networks can strengthen or weaken with use. So, join a mindful meditation class or download a mindful meditation app and train your brain to get out of the default mode network and be present!” – Mclean Bolton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

Weng, H. Y., Lewis-Peacock, J. A., Hecht, F. M., Uncapher, M. R., Ziegler, D. A., Farb, N., Goldman, V., Skinner, S., Duncan, L. G., Chao, M. T., & Gazzaley, A. (2020). Focus on the Breath: Brain Decoding Reveals Internal States of Attention During Meditation. Frontiers in Human Neuroscience, 14, 336. https://doi.org/10.3389/fnhum.2020.00336

Abstract

Meditation practices are often used to cultivate interoception or internally-oriented attention to bodily sensations, which may improve health via cognitive and emotional regulation of bodily signals. However, it remains unclear how meditation impacts internal attention (IA) states due to lack of measurement tools that can objectively assess mental states during meditation practice itself, and produce time estimates of internal focus at individual or group levels. To address these measurement gaps, we tested the feasibility of applying multi-voxel pattern analysis (MVPA) to single-subject fMRI data to: (1) learn and recognize internal attentional states relevant for meditation during a directed IA task; and (2) decode or estimate the presence of those IA states during an independent meditation session. Within a mixed sample of experienced meditators and novice controls (N = 16), we first used MVPA to develop single-subject brain classifiers for five modes of attention during an IA task in which subjects were specifically instructed to engage in one of five states [i.e., meditation-related states: breath attention, mind wandering (MW), and self-referential processing, and control states: attention to feet and sounds]. Using standard cross-validation procedures, MVPA classifiers were trained in five of six IA blocks for each subject, and predictive accuracy was tested on the independent sixth block (iterated until all volumes were tested, N = 2,160). Across participants, all five IA states were significantly recognized well above chance (>41% vs. 20% chance). At the individual level, IA states were recognized in most participants (87.5%), suggesting that recognition of IA neural patterns may be generalizable for most participants, particularly experienced meditators. Next, for those who showed accurate IA neural patterns, the originally trained classifiers were applied to a separate meditation run (10-min) to make an inference about the percentage time engaged in each IA state (breath attention, MW, or self-referential processing). Preliminary group-level analyses demonstrated that during meditation practice, participants spent more time attending to breath compared to MW or self-referential processing. This paradigm established the feasibility of using MVPA classifiers to objectively assess mental states during meditation at the participant level, which holds promise for improved measurement of internal attention states cultivated by meditation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483757/

 

Magnetic Resonance Imaging (MRI) Procedure can Alter Meditation and its Effects on the Brain

psyjdc Leave a comment

Magnetic Resonance Imaging (MRI) Procedure can Alter Meditation and its Effects on the Brain

 

By John M. de Castro, Ph.D.

 

“The nature of the high noise levels present during fMRI makes total elimination of imager noise perceived by subjects impractical at this time.” – Michael Ravicz

 

Meditation training has been shown to improve health and well-being. It has also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. There are a number of ways that meditation practices produce these benefits, including changes to the brain and physiology.

 

The premiere way of measuring brain size and function is Magnetic Resonance Imaging (MRI). But the recording of the MRI can be difficult for the participant as they are confined in a narrow tube for an extended period of time with very high noise levels. There are attempts to mitigate the effects of this recording environment but even at best it is noxious for the participant. It is not known how this environment of MRI recording may affect the results of studies of meditation effects on the brain.

 

In today’s Research News article “Does the MRI/fMRI Procedure Itself Confound the Results of Meditation Research? An Evaluation of Subjective and Neurophysiological Measures of TM Practitioners in a Simulated MRI Environment.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198852/ ) Travis and colleagues recruited experienced meditators and recorded their brain activity with electroencephalogram during a single session while they had their eyes closed and then meditated for 7 minutes. This sequence was repeated in counterbalanced order for sitting, lying down in the quiet, and lying down in a simulated MRI tube with 110db recording of the noise sound level of an MRI machine. The participants then completed a questionnaire about the depth of their meditation and their subjective experiences.

 

They found that the participants rated their depth of meditation and experiences of pure consciousness significantly lower and interference and distraction/agitation significantly higher during the simulated MRI condition. The power in most frequency bands significantly decreased in the EEG from sitting to lying positions and further significantly decreased during the simulated MRI condition. In addition, during the simulated MRI condition, there was a significant increase in activation of the precuneus area of the brain, a major component of the default mode network.

 

These findings are interesting and important for the interpretation of meditation research employing MRI to investigate its effects on the brain. The results suggest that the conditions of MRI recording, including confinement and loud noise levels alters the nature of the meditation and the brain’s responses to the meditation. This environment appears to interfere with the depth of the meditation and inserts greater distractions producing agitation. The MRI environment also appears to decrease the power of various waveforms in the EEG and activate the default mode network of the brain.

 

This represents a problem for interpreting MRI data recorded during meditation. Of course, the effects of the MRI recording environment would be the same during different conditions. So, differences between MRI data recorded during meditation and during other mental states should not be due to the recording environment. In addition, the disruption of the meditation produced by the environment would likely make it more difficult to detect changes produced by meditation. So, the actual observed brain changes during meditation in the MRI environment may underestimate the true effects of meditation practice on the brain.

 

So, Magnetic Resonance Imaging (MRI) procedure can alter meditation and its effects on the brain.

 

“claustrophobia is common in the world of MRI. It’s so common that asking questions about it is standard in the pre-appointment screening call. “Four out of ten patients that we call will mention something about claustrophobia,” – Desiree Rckovich

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Travis, F., Nash, J., Parim, N., & Cohen, B. H. (2020). Does the MRI/fMRI Procedure Itself Confound the Results of Meditation Research? An Evaluation of Subjective and Neurophysiological Measures of TM Practitioners in a Simulated MRI Environment. Frontiers in psychology, 11, 728. https://doi.org/10.3389/fpsyg.2020.00728

 

Abstract

Early research into meditation, including Transcendental Meditation (TM), relied exclusively on EEG to measure brain activity during meditation practice. Since the advent of neural imaging, MRI, and later fMRI, have dominated this field. Unfortunately, the use of this technology rests on the questionable assumption that lying down in a confining tube while exposed to very loud sounds would not interfere with the meditation practice. The present study was designed to assess the effects of the fMRI procedure on both the subjective and neurophysiological responses of short and long-term TM practitioners. Twenty-three TM practitioners volunteered to participate in this study: 11 short-term meditators, averaging 2.2 years practice, and 12 long-term meditators, averaging 34.8 years. The repeated-measures design included two activities for each participant, eyes-closed rest, and TM practice, in each of three conditions: sitting quietly in an upright position (normal TM practice); lying quietly in a supine position; and lying, with earplugs, inside a simulated fMRI tube (simMRI), while exposed to 110 dB recordings of an actual fMRI machine. Subjective experiences were collected after each activity in each condition. Physiological arousal was recorded using skin conductance levels. Scalp EEG was averaged into eight frequency bands within frontal and parietal leads; eLORETA software was used to explore the 3-D cortical distribution of EEG sources. During the simMRI condition, participants reported having more shallow meditation experiences, and greater agitation/distraction. Skin conductance levels paralleled self-reports, decreasing least during the simMRI condition. Frontal and parietal power decreased from sitting to simMRI in the alpha2 through gamma bands. Parietal power was higher during rest compared to TM in the alpha1 through beta2 bands. Frontal and parietal alpha1 coherence were highest during the simMRI condition. The eLORETA analysis revealed that the default mode network was more active during TM when sitting compared to the simMRI condition. The responses to the supine condition were generally between sitting and simMRI, with some significant exceptions. In conclusion, these data indicate that the fMRI procedure itself (high dB noise; lying down) strongly influences subjective and neurophysiological responses during meditation practice, and may therefore confound the interpretation of results from fMRI studies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198852/

Improve Attention and Memory with Closed-Loop Digital Meditation

psyjdc Leave a comment

Improve Attention and Memory with Closed-Loop Digital Meditation

 

By John M. de Castro, Ph.D.

 

“The good news is that its possible to train your attention and gain the associated benefits, and practicing mindfulness offers one of the most accessible and effective approaches.” – Deborah Schoeberlein David

 

There has accumulated a large amount of research demonstrating that mindfulness has significant benefits for psychological, physical, and spiritual wellbeing. It even improves high level thinking known as executive function and emotion regulation and compassion. One of the primary effects of mindfulness training is an improvement in the ability to pay attention to the task at hand and ignore interfering stimuli. This is an important consequence of mindfulness training and produces improvements in thinking, reasoning, and creativity. The importance of heightened attentional ability to the individual’s ability to navigate the demands of complex modern life cannot be overstated. It helps in school, at work, in relationships, or simply driving a car. As important as attention is, it’s surprising that little is known about the mechanisms by which mindfulness improves attention.

 

There is evidence that mindfulness training improves attention by altering the brain. It appears That mindfulness training increases the size, connectivity, and activity of areas of the brain that are involved in paying attention. One way to observe the effects of meditation is to measure changes in the electroencephalogram (EEG), the rhythmic electrical activity that can be recorded from the scalp. The recorded activity can be separated into frequency bands. Theta activity consists of oscillations in the 4-8 cycles per second band and it thought to measure attention. Another method to observe attentional processing in the brain is to measure the changes in the electrical activity that occur in response to paying attention. These are called event-related potentials or ERPs. The signal following a stimulus changes over time. The fluctuations of the signal after specific periods of time are thought to measure different aspects of the nervous system’s processing of the stimulus. The P300 response in the evoked potential (ERP) is a positive going electrical response occurring between a 1.5 to 5.0 tenths of a second following the target stimulus presentation. The P300 component is thought to reflect attentional processes.

 

In today’s Research News article “Closed-loop digital meditation improves sustained attention in young adults.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534732/ ) Ziegler and colleagues recruited meditation-naïve young adults and randomly assigned them to a placebo control group or to receive 6 weeks of daily online breath following focused meditation training. Initially they meditated for 20 minutes but as they reported greater and greater ability to pay attention to their breath the duration of the meditation increased up to 30 minutes. The placebo control condition was engagement with an online app that was judged by participants to produce expectations equivalent to the meditation app for improvements in sustained attention and working memory. Three online aps were identified and self-selected by the participants of foreign language learning, Tai Chi practice, or logic games. The participants were measured before and after training for sustained attention, distraction filtering, working memory, and accuracy of working memory. They also recoded the electroencephalogram (EEG) during the sustained attention task and recorded the theta rhythm and the P300 evoked potentials to the attention stimuli.

 

They found that in comparison to the placebo group the meditation group had significant increases in sustained attention, distraction filtering, and working memory. In addition, they found that the greater the duration of the meditation practice achieved the greater the improvement in sustained attention. In the EEG they found that the meditation group had significant increases in attention-related EEG measures. In particular, they had increased frontal midline theta rhythm and earlier parietal P300 latencies in the evoked potentials.

 

Previous studies have shown that mindfulness practices produce improvements in attention and memory. An interesting and important difference between this research and prior research is that they employed a control condition that was demonstrated to produce the same degree of expectation in the participants for improvement in attention and memory. In other words. they controlled for participant expectancy, placebo, effects that were not controlled in the prior work. So, the improvements in attention and working memory were likely due to the meditation practice itself. Another interesting difference was that the present results were both in behavioral and brain activity measures. This demonstrates that the effects can be seen in objective, EEG and evoked potential data, and not just in behavioral responses that are more susceptible to bias.

 

So, improve attention and memory with closed-loop digital meditation.

 

“mindful attention improves attention regulation, benefits physical and mental health, reduces stress, facilitates emotion regulation, and helps you remove those extra pounds!” – Gavin Khoury

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Ziegler, D. A., Simon, A. J., Gallen, C. L., Skinner, S., Janowich, J. R., Volponi, J. J., Rolle, C. E., Mishra, J., Kornfield, J., Anguera, J. A., & Gazzaley, A. (2019). Closed-loop digital meditation improves sustained attention in young adults. Nature human behaviour, 3(7), 746–757. https://doi.org/10.1038/s41562-019-0611-9

 

Abstract

Attention is a fundamental cognitive process that is critical for essentially all aspects of higher-order cognition and real-world activities. Younger generations have deeply embraced information technology and multitasking in their personal lives, school, and the workplace, creating myriad challenges to their attention. While improving sustained attention in healthy young adults would be beneficial, enhancing this ability has proven notoriously difficult in this age group. Here we show that six-weeks of engagement with a meditation-inspired, closed-loop software program (MediTrain) delivered on mobile devices led to gains in both sustained attention and working memory in healthy young adults (n = 22). These improvements were associated with positive changes in key neural signatures of attentional control (frontal theta inter-trial coherence and parietal P3b latency), as measured by electroencephalography. Our findings suggest the utility of delivering aspects of the ancient practice of focused-attention meditation in a modern, technology-based approach and its benefits on enhancing sustained attention.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534732/

 

Change the Brain for Greater Happiness with Meditation

psyjdc Leave a comment

Change the Brain for Greater Happiness with Meditation

 

By John M. de Castro, Ph.D.

 

“meditation. . . appears to have an amazing variety of neurological benefits – from changes in grey matter volume to reduced activity in the “me” centers of the brain to enhanced connectivity between brain regions.” – Alice Walton

 

There has accumulated a large amount of research demonstrating that meditation practice has significant benefits for psychological, physical, and spiritual wellbeing. It has been shown to improve emotions and their regulation. It also increases happiness levels in practitioners. One way that meditation practices may produce these benefits is by altering the brain. The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity. Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread areas. In other words, meditation practice appears to mold and change the brain, producing greater happiness.

 

In today’s Research News article “Rajyoga meditation induces grey matter volume changes in regions that process reward and happiness.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528075/ ) Babu and colleagues recruited participants who practiced Rajyoga meditation and a group of non-meditators matched for age, gender, and handedness. Rajyoga meditation is an eyes-open focused meditation practice focusing on a point of light. They completed a measure of happiness and had their brains scanned with Magnetic Resonance Imaging (MRI).

 

They found that the Rajyoga meditators were significantly happier than the non-meditators and that the greater the number of hours of practice the greater the levels of happiness. The MRI scans revealed that the Rajyoga meditators had significantly great gray matter volume in the superior frontal gyrus, inferior orbitofrontal cortex, and precuneus. They also found that the greater the gray matter volume in the superior frontal gyrus, orbitofrontal cortex, insula, and anterior cingulate cortex the greater the levels of reported happiness.

 

The results of the present study need to be interpreted with caution as the groups were determined by whether they engaged in meditation or not. It is possible that people who choose to meditate are significantly different and have significantly different brains than those who do not. Nevertheless, the results suggest that Rajyoga meditators are happier and have greater amounts of brain matter in specific regions of the brain than non-meditators and that these changes are correlated with happiness. The brain areas with greater volume in the meditators are thought to process information regarding rewards and happiness. So, it is hypothesized that the meditation alters these brain regions that results in greater happiness.

 

So, change the brain for greater happiness with meditation.

 

“meditation physically impacts the extraordinarily complex organ between our ears. Recent scientific evidence confirms that meditation nurtures the parts of the brain that contribute to well-being. Furthermore, it seems that a regular practice deprives the stress and anxiety-related parts of the brain of their nourishment.“ – Mindworks

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Babu, M., Kadavigere, R., Koteshwara, P., Sathian, B., & Rai, K. S. (2020). Rajyoga meditation induces grey matter volume changes in regions that process reward and happiness. Scientific reports, 10(1), 16177. https://doi.org/10.1038/s41598-020-73221-x

 

Abstract

Studies provide evidence that practicing meditation enhances neural plasticity in reward processing areas of brain. No studies till date, provide evidence of such changes in Rajyoga meditation (RM) practitioners. The present study aimed to identify grey matter volume (GMV) changes in reward processing areas of brain and its association with happiness scores in RM practitioners compared to non-meditators. Structural MRI of selected participants matched for age, gender and handedness (n = 40/group) were analyzed using voxel-based morphometric method and Oxford Happiness Questionnaire (OHQ) scores were correlated. Significant increase in OHQ happiness scores were observed in RM practitioners compared to non-meditators. Whereas, a trend towards significance was observed in more experienced RM practitioners, on correlating OHQ scores with hours of meditation experience. Additionally, in RM practitioners, higher GMV were observed in reward processing centers—right superior frontal gyrus, left inferior orbitofrontal cortex (OFC) and bilateral precuneus. Multiple regression analysis showed significant association between OHQ scores of RM practitioners and reward processing regions right superior frontal gyrus, left middle OFC, right insula and left anterior cingulate cortex. Further, with increasing hours of RM practice, a significant positive association was observed in bilateral ventral pallidum. These findings indicate that RM practice enhances GMV in reward processing regions associated with happiness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528075/

 

Increase Brain-Derived Neurotrophic Factor (BDNF) with Mindfulness

psyjdc Leave a comment

Increase Brain-Derived Neurotrophic Factor (BDNF) with Mindfulness

 

By John M. de Castro, Ph.D.

 

“BDNF is a key neurotrophin that promotes development, survival and plasticity of neurons in the central and peripheral nervous systems.” – B. Rael Cahn

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity.  Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread area. and have found that meditation practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. These brain changes with mindfulness practice are important and need to be further investigates.

 

Brain-Derived Neurotrophic Factor (BDNF) is a key molecule circulating in the blood that promotes neural, neuronal survival and regeneration which produces neuroplasticity. There have been a number of studies performed on the ability of Mindfulness practices to affect the levels of BDNF found in the blood. It makes sense, then to review what has been learned.

 

In today’s Research News article “The Effect of Mindfulness-Based Intervention on Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-Analysis of Controlled Trials.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2020.02209/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1437459_69_Psycho_20200922_arts_A ) Gomutbutra and colleagues review, summarize, and perform a meta-analysis of the effects of mindfulness practices on the circulating levels of Brain-Derived Neurotrophic Factor (BDNF). They identified 11 published randomized controlled trials.

 

They report that the published research studies found that mindfulness training either by meditation or yoga practice produced a significant increase in circulating levels of Brain-Derived Neurotrophic Factor (BDNF). Hence the published research suggests that meditation and yoga practice produce increased levels of BDNF in the blood. Since BDNF promotes neuroplasticity, this may be the mechanism by which mindfulness practices change the brain and thereby improve health and well-being. Of course, much more research is needed but this is a promising potential mechanism whereby mindfulness produces its benefits.

 

So, Increase Brain-Derived Neurotrophic Factor (BDNF) with Mindfulness.

 

“mindfulness meditation and mind-body exercise (e.g. yoga and tai chi) increase circulating BDNF concentrations in healthy and diseased individuals.” – Tongjian You

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Gomutbutra P, Yingchankul N, Chattipakorn N, Chattipakorn S and Srisurapanont M (2020) The Effect of Mindfulness-Based Intervention on Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-Analysis of Controlled Trials. Front. Psychol. 11:2209. doi: 10.3389/fpsyg.2020.02209

 

Background: This systematic review aims to answer three questions. First, how much do mindfulness-based interventions (MBIs) affect peripheral brain-derived neurotrophic factor (BDNF)? Second, do mindfulness exercise–based interventions (exercise-MBIs) and mindfulness meditation–based interventions (meditation-MBIs) affect peripheral BDNF differently? Third, does the age of participants and the accumulative hours of MBI practice affect peripheral BDNF?

Methods: We included randomized controlled trials comparing MBI and no intervention in adults (age >18 years) who reported peripheral BDNF. Database searches included PubMed, CINAHL, CENTRAL, PsyInfo, and Scopus. Two reviewers independently selected the studies and assessed the trial quality. We used the standardized mean difference (SMD) as the effect size index and conducted moderator analyses.

Results: Eleven studies are included in this systematic review. Five studies applying exercise-MBI and three studies applying meditation-MBI are included in the meta-analysis (N = 479). The pooled effect size shows a significantly greater increase of peripheral BDNF in MBI groups compared to the control groups (k = 8, N = 479, SMD = 0.72, 95% CI 0.31–1.14, I2= 78%). Significantly more increases of BDNF in the MBI groups are found in both subgroups of exercise-MBI and meditation-MBI. The effect sizes of both subgroups are not significantly different between subgroups (χ2 = 0.02, p = 0.88). We find no significant correlation between the effect sizes and the age of participants (r = −0.0095, p = 0.45) or accumulative hours of MBI practice (r = 0.0021, p = 0.57).

Conclusion: The heterogeneous data of this small sample-size meta-analysis suggests that MBI can increase peripheral BDNF. Either exercise-MBI or meditation-MBI can increase peripheral BDNF.

https://www.frontiersin.org/articles/10.3389/fpsyg.2020.02209/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1437459_69_Psycho_20200922_arts_A

 

Characteristics of the Oneness Experience in Experienced Meditators

psyjdc Leave a comment

Characteristics of the Oneness Experience in Experienced Meditators

 

By John M. de Castro, Ph.D.

 

“Imagine there is no past or future, only now. Imagine there is no space or time, just an unbounded eternity. Imagine endless peace, harmony, and unconditional love. Imagine no fear and equality in all things. This is Oneness.” – Roger Gabriel

 

Millions of people worldwide seek out transcendent experiences by engaging in practices, such as meditation, yoga, and prayer. Others use drugs such as peyote, mescaline, LSD, ayahuasca and psilocybin to induce these experiences. Transcendent experiences have many characteristics which are unique to the experiencer, their religious context, and their present situation. But, the common, central feature of transcendence is a sense of oneness, that all things are contained in a single thing, a sense of union with the universe and/or God and everything in existence. This includes a loss of the personal self. What they used to refer to as the self is experienced as just a part of an integrated whole. People who have had these experiences report feeling interconnected with everything else in a sense of oneness with all things. Although transcendent experiences can vary widely, they all contain this experience of oneness.

 

Unfortunately, there is very little systematic research on the oneness experience. In today’s Research News article “Understanding the Nature of Oneness Experience in Meditators Using Collective Intelligence Methods.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2020.02092/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1437459_69_Psycho_20200922_arts_A ) Van Lente and colleagues recruited participants who had meditated for at least 5 years and who had experienced “oneness”. They met in groups on 5 occasions of about 3 hours each and discussed the nature of the “oneness” experience employing a structured technique called Interactive Management (IM).

 

The participants first individually generated ideas about the “oneness” experience. They then reviewed as a group the ideas generated and clarified and categorized the ideas. They then voted individually on the 5 best ideas of “oneness self-perceptions they believed most characterized their experience both during meditation and in their everyday experience in the world”. Finally, they investigated the relationships among the ideas regarding the “oneness” experience.

 

The participants generated 130 ideas about the “oneness” experience. These were analyzed and summarized into categories. From this analysis they concluded that “oneness” experiences involved perception, affect, cognition, motivation, action, and interpersonal relations. The most influential categories of oneness experience were unboundedness, identity–perception change, time–perception change, wholeness, and changes in action orientation.

 

Unboundedness referred to the perception that there were no boundaries between objects as they were seen as all together in a single entity. The idea of identity–perception change identified the self as also unbounded and not separate from everything else, but part of the whole. The idea of time–perception change was that there was only a timeless present moment. In the “oneness” experience there is no past or future, only now. The idea of wholeness involves seeing everything as part of a greater whole that is unbounded, integrated, and singular. Finally, the idea of changes in action orientation indicates a flow to experienced reality such that experiences flow seamlessly and all together. All of this led to the affective experience of total well-being.

 

These are interesting results produced by a structured process to determine the nature of “oneness” experiences that occurred in experienced meditators. In essence, in these experiences, they perceived a totality of experience occurring only in the present moment that involved everything integrated together, including the individuals themselves, and flowing seamlessly together. The ideas generated were very similar to ideas generated by individual anecdotes of “oneness” experiences or psychometric analysis.

 

It should be mentioned that the “oneness” experience is just that, an experience, and like all experiences cannot be adequately captured by words and concepts. The present analysis does the best it can at producing a conceptual analysis of the “oneness” experience. But inevitably it falls short of capturing the actual experiences of the individuals. In the literature on the “oneness” experience, it is referred to an ineffable, unable to be described adequately in words. To truly know the “oneness” experience it must be experienced.

 

“Oneness is an experience that transcends the mind. When we experience oneness, we feel a connection with everything in existence on every level. In other words, we feel ‘at one’ with all things.” –  Mateo Sol

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Van Lente E and Hogan MJ (2020) Understanding the Nature of Oneness Experience in Meditators Using Collective Intelligence Methods. Front. Psychol. 11:2092. doi: 10.3389/fpsyg.2020.02092

 

Research on meditation and mindfulness practice has flourished in recent years. While much of this research has focused on well-being outcomes associated with mindfulness practice, less research has focused on how perception of self may change as a result of mindfulness practice, or whether these changes in self-perception may be mechanisms of mindfulness in action. This is somewhat surprising given that mindfulness derives from traditions often described as guiding people to realize and experience the non-separation of self from the world or its “oneness” with the whole of reality. The current study used a collective intelligence methodology, Interactive Management (IM), to explore the nature of oneness experiences. Five IM sessions were conducted with five separate groups of experienced meditators. Participants generated, clarified, and selected oneness self-perceptions they believed most characterized their experience both during meditation and in their everyday experience in the world. Each group also developed structural models describing how highly ranked aspects of oneness self-perceptions are interrelated in a system. Consistent themes and categories of oneness experience appeared across the five IM sessions, with changes in the sense of space (unboundedness), time, identity, wholeness, and flow highlighted as most influential. Results are discussed in light of emerging theory and research on oneness self-perception and non-dual awareness.

https://www.frontiersin.org/articles/10.3389/fpsyg.2020.02092/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1437459_69_Psycho_20200922_arts_A

 

Meditation Changes the Brain Differently in Adolescents

psyjdc Leave a comment

Meditation Changes the Brain Differently in Adolescents

 

By John M. de Castro, Ph.D.

 

“The benefits of meditation are many with few, if any, drawbacks. If your teen is struggling, it’d be worth it to give it a try.” – Tyler Jacobson

 

There has accumulated a large amount of research demonstrating that mindfulness has significant benefits for psychological, physical, and spiritual wellbeing. It even improves high level thinking known as executive function. Its positive effects are so widespread that it is difficult to find any other treatment of any kind with such broad beneficial effects on everything from thinking to mood and happiness to severe mental and physical illnesses. This raises the question of how mindfulness training could produce such widespread and varied benefits. One possibility is that mindfulness practice results in beneficial changes in the nervous system.

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity. Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread areas. In other words, mindfulness practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. The brains of adolescents are different from fully mature adult brains. They are dynamically growing and changing. It is unclear how mindfulness affects their maturing brains.

 

In today’s Research News article “Gray Matter Changes in Adolescents Participating in a Meditation Training.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456888/ ) Yuan and colleagues recruited adolescents aged 14 to 19 years and provided them with a 12 week training in mindfulness meditation. They and a control sample of adolescents underwent Magnetic Resonance Imaging (MRI) of their brains before and after training.

 

They found that after training there was a significant reduction in the volume of gray matter in the left thalamus, left putamen, and left posterior insula. There was no significant influence of age on the decreased volumes. Also, there were no significant increases in gray matter volume were found anywhere in the adolescents’ brains.

 

These results are very surprising. In adults, mindfulness training has been repeatedly shown to increase gray matter volume, not decrease it. The insula, in particular, has been shown to increase in volume after mindfulness training in adults. The insula is thought to underlie awareness of the internal state of the body. Since, mindfulness training usually increases this awareness, the increase in insula volume makes sense, but that it would decrease in volume in the adolescents does not.

 

During adolescents the brain is actively growing and changing. It is possible that mindfulness training affects the growing brain differently than after maturation in adulthood. This suggests that mindfulness may have different effects in adolescents than in adults. But this has not been shown to be the case. In fact, mindfulness training appears to have the same effects in adolescents as in adults. More research is needed to further investigate this phenomenon.

 

So, it would appear that meditation changes the brain differently in adolescents.

 

“It is well-documented that mindfulness helps to relieve depression and anxiety in adults.  A small but growing body of research shows that it may also improve adolescent resilience to stress through improved cognitive performance and emotional regulation.” – Malka Main

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Justin P. Yuan, Colm G. Connolly, Eva Henje, Leo P. Sugrue, Tony T. Yang, Duan Xu, Olga Tymofiyeva. Gray Matter Changes in Adolescents Participating in a Meditation Training. Front Hum Neurosci. 2020; 14: 319. Published online 2020 Aug 14. doi: 10.3389/fnhum.2020.00319

 

Abstract

Meditation has shown to benefit a wide range of conditions and symptoms, but the neural mechanisms underlying the practice remain unclear. Magnetic resonance imaging (MRI) studies have investigated the structural brain changes due to the practice by examining volume, density, or cortical thickness changes. However, these studies have focused on adults; meditation’s structural effects on the adolescent brain remain understudied. In this study, we investigated how meditation training affects the structure of the adolescent brain by scanning a group of 38 adolescents (16.48 ± 1.29 years) before and after participating in a 12-week meditation training. Subjects underwent Training for Awareness, Resilience, and Action (TARA), a program that mainly incorporates elements from mindfulness meditation and yoga-based practices. A subset of the adolescents also received an additional control scan 12 weeks before TARA. We conducted voxel-based morphometry (VBM) to assess gray matter volume changes pre- to post-training and during the control period. Subjects showed significant gray matter (GM) volume decreases in the left posterior insula and to a lesser extent in the left thalamus and left putamen after meditation training. There were no significant changes during the control period. Our results support previous findings that meditation affects regions associated with physical and emotional awareness. However, our results are different from previous morphometric studies in which meditation was associated with structural increases. We posit that this discrepancy may be due to the differences between the adolescent brain and the adult brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456888/

 

Meditation Improves Health and Well-Being Through Epigenetic Mechanisms

psyjdc Leave a comment

Meditation Improves Health and Well-Being Through Epigenetic Mechanisms

 

By John M. de Castro, Ph.D.

 

“It seems unusual that something as simple and easy as meditating could improve your health, but these studies demonstrate an epigenetic link between meditation and its potential disease-reducing benefits.” – Bailey Kirkpatrick

 

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

 

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. There have been a number of research studies of the of the epigenetic effects of mindfulness practices. So, it makes sense to summarize what has been learned regarding the epigenetic alterations in gene expressions produced by mindfulness practices to determine if these effects are the intermediary between meditation and health.

 

In today’s Research News article “Molecules of Silence: Effects of Meditation on Gene Expression and Epigenetics.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431950/) Venditti and colleagues review and summarize the published research studies of the effects of mindfulness on gene expression.

 

They report that the published research found that sitting and walking meditation, Tai Chi, and Yoga produce wide-ranging changes in gene expression including slowing of the age-related methylation of the genes. They report that the epigenetic changes seen alter genes involved in metabolism, inflammatory processes, oxidative stress, and DNA damage response. In fact, they report that mindfulness practices produce epigenetic changes that are the opposite to those produced by stress.

 

These findings are important for understanding the ability of mindfulness practices to promote health and slow the aging process. By reversing the changes that stress produces in gene expression, mindfulness practices can prevent or reverse the harmful consequences of stress on the body. This may well be one of the mechanisms that underlie the health benefits of mindfulness practices.

 

So, meditation improves health and well-being through epigenetic mechanisms.

 

“a single 8-hour mindfulness meditation retreat can rapidly alter methylation levels that affect epigenetic expression in genes among experienced meditators. Involved genes include those that regulate inflammation, immune cell metabolism, DNA repair, cellular aging, RNA metabolism, protein translation, cell adhesion, and neurotransmission.” – AMRA

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Venditti, S., Verdone, L., Reale, A., Vetriani, V., Caserta, M., & Zampieri, M. (2020). Molecules of Silence: Effects of Meditation on Gene Expression and Epigenetics. Frontiers in psychology, 11, 1767. https://doi.org/10.3389/fpsyg.2020.01767

 

Abstract

Many studies have consistently demonstrated an epigenetic link between environmental stimuli and physiological as well as cognitive responses. Epigenetic mechanisms represent a way to regulate gene activity in real time without modifying the DNA sequence, thus allowing the genome to adapt its functions to changing environmental contexts. Factors such as lifestyle, behavior, and the practice of sitting and moving mindful activities have been shown to be important means of environmental enrichment. Such practices, which include mindfulness meditation, Vipassana, Yoga, Tai Chi, and Quadrato Motor Training, have been reported to positively impact well-being. In fact, they can be considered emotional and attentional regulatory activities, which, by inducing a state of greater inner silence, allow the development of increased self-awareness. Inner silence can therefore be considered a powerful tool to counteract the negative effects of overabundant environmental noise, thanks to its power to relieve stress-related symptoms. Since all these positive outcomes rely on physiological and biochemical activities, the molecular and epigenetic mechanisms influenced by different mindful practices have recently started to be investigated. Here, we review some of the findings that could allow us to uncover the mechanisms by which specific practices influence well-being.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431950/