Improve Doctors’ Empathy and Communication Skills with Loving-Kindness Meditation

November 8, 2021 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“Medicine and meditation, etymologically, come from the same root: to consider, advise, reflect, to take appropriate measures,” – Ronald Epstein

Stress is epidemic in the western workplace with almost two thirds of workers reporting high levels of stress at work. In high stress occupations, like healthcare, the stress can produce fatigue, cynicism, emotional exhaustion, sleep disruption, and professional inefficacy. This not only affects the healthcare providers personally, but also the patients, as it produces a loss of empathy and compassion.

Loving Kindness Meditation is designed to develop kindness and compassion to oneself and others. The individual systematically pictures different individuals from self, to close friends, to enemies and wishes them happiness, well-being, safety, peace, and ease of well-being. It is possible that Loving Kindness Meditation can help to reverse the effects of stress on medical providers and increase their levels of empathy and compassion for their patients and improve their communications with their patients.

In today’s Research News article “Effects of Loving-Kindness Meditation on Doctors’ Mindfulness, Empathy, and Communication Skills.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069630/ ) Chen and colleagues recruited doctors at a hospital in China who had practiced for at least 3 years and randomly assigned them to receive either a 90-minute Loving Kindness Meditation practice 3 times per week for 8 weeks or to be in a wait-list control condition. They were measured before and after training for mindfulness, empathy, and communication skills.

They found that in comparison to baseline and the wait-list control group, the doctors who received Loving Kindness Meditation had significant increases in empathy and communications skills, but not mindfulness. These results replicate previous findings that Loving Kindness Meditation produces significant improvements in empathy.

This study used a passive control condition (wait-list) which makes the interpretation of results subject to possible confounding explanations such as placebo effects, experimenter bias, Hawthorne effects, etc. Future studies should include an active control condition, e.g. exercise. Nevertheless, the results suggest that practicing Loving Kindness Meditation may improve a physicians ability to understand the emotions of their patients and be better able to communicate with them. This would make them much better doctors and improve patient care and clinical outcomes. It remains for future research to examine if this outcome occurs in actual clinical practice.

So, improve doctors’ empathy and communication skills with Loving-Kindness Meditation.

“Clear communication from doctors may have a healing effect. Studies on pain perception find that, similar to the placebo effect, thoughtfully walking a patient through a procedure that is being administered, or one that will occur in the future, can make them less anxious and more optimistic, leading to less pain.” – Deborah Wip

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Chen, H., Liu, C., Cao, X., Hong, B., Huang, D. H., Liu, C. Y., & Chiou, W. K. (2021). Effects of Loving-Kindness Meditation on Doctors’ Mindfulness, Empathy, and Communication Skills. International journal of environmental research and public health, 18(8), 4033. https://doi.org/10.3390/ijerph18084033

Abstract

Background: In the context of increasing doctor–patient tensions in China, the objective of this study was to explore and examine the effects of loving-kindness meditation (LKM) on doctors’ mindfulness, empathy, and communication skills. Methods: A total of 106 doctors were recruited from a hospital in China, and randomly divided into an LKM training group (n = 53) and waiting control group (n = 53). The LKM training group received 8 weeks of LKM training intervention, whereas the control group received no intervention. Three major variables (mindfulness, empathy, and communication skills) were measured before (pre-test) and after (post-test) the LKM training intervention. Results: The empathy and communication skills of the LKM group were significantly improved compared with those of the control group, but the level of mindfulness did not significantly change. Conclusions: The results suggested that LKM may contribute to improving physicians’ empathy and communication skills. However, the mechanisms that underlie the effects of the LKM on mindfulness, empathy, and communication skills and other psychological constructs needs further elucidation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069630/

wkchiu@mail.cgu.edu.tw

Alter the Genes for Better Health with Meditation

November 6, 2021 psyjdc Leave a comment

Alter the Genes for Better Health with Meditation

By John M. de Castro, Ph.D.

“meditation practices seem . . . promote endocrinal, neuronal, and behavioral functions. This suggests that the achievement of a state of inner silence through the practice of meditation can prevent or reverse the detrimental effects of a stressful environment.“ – Sabrina Venditti

Over the last several decades, research and anecdotal experiences have accumulated an impressive evidential case that the development of mindfulness has positive benefits for the individual’s mental, physical, and spiritual life. Mindfulness appears to be beneficial both for healthy people and for people suffering from a myriad of illnesses. It appears to be beneficial across ages, from children to the elderly. And it appears to be beneficial across genders, personalities, race, and ethnicity. The breadth and depth of benefits is unprecedented.

Meditation practice has been shown to improve health and longevity. One way it appears to act is by altering the genes which govern cellular processes in our bodies. The genes dictate all of the chemical processes in our bodies including immune and inflammatory responses. The ability of outside influences to affect gene expression is known as epigenetics. Hence, it is important to study the epigenetic alterations in gene expressions produced by meditation practice to determine if these effects are the intermediary between meditation and health.

In today’s Research News article “Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/ ) Wenuganen and colleagues recruited older (> 60 years of age) healthy adult experienced practitioners of Transcendental Meditation and matched non-practitioners. Blood was drawn and analyzed for gene expression with microarrays and polymerase chain reaction.

They found that the genes of the Transcendental Meditation practitioners were in general significantly downregulated (lower expression) than the non-practitioners. “Sixty-two genes were related to hematologic diseases, 26 to coronary artery disease, 34 to diabetes complications, 49 to inflammation, and 64 to CVD. All these disease-related genes were downregulated in the TM group relative to the control group.” The genes found to have lower expression in the Transcendental Meditation practitioners were related to inflammatory responses and suppressed energy efficiency, while those upregulated (higher expression) were related to immune system function.

These epigenetic findings suggest that Transcendental Meditation practice over years of practice improve the immune system and energy efficiency while reducing inflammation in older individuals. These epigenetic changes suggest that Transcendental Meditation practice improves the physiology’s ability to maintain health by being better prepared to respond to disease and stress. This suggests a mechanism by which meditation practice improves health and longevity.

So, alter the genes for better health with meditation.

“meditation, yoga, and Tai Chi . . . all seem to have a beneficial effect on the expression of a slew of different genes. And, as you might expect, the affected genes are generally those involved in stress and inflammation.” – Alice Walton

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are a

Alter the Genes for Better Health with Meditation

By John M. de Castro, Ph.D.

So, alter the genes for better health with meditation.

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are available at the Contemplative Studies Blog http://contemplative-studies.org/wp/

They are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Wenuganen, S., Walton, K. G., Katta, S., Dalgard, C. L., Sukumar, G., Starr, J., Travis, F. T., Wallace, R. K., Morehead, P., Lonsdorf, N. K., Srivastava, M., & Fagan, J. (2021). Transcriptomics of Long-Term Meditation Practice: Evidence for Prevention or Reversal of Stress Effects Harmful to Health. Medicina (Kaunas, Lithuania), 57(3), 218. https://doi.org/10.3390/medicina57030218

Abstract

Background and Objectives: Stress can overload adaptive mechanisms, leading to epigenetic effects harmful to health. Research on the reversal of these effects is in its infancy. Early results suggest some meditation techniques have health benefits that grow with repeated practice. This study focused on possible transcriptomic effects of 38 years of twice-daily Transcendental Meditation® (TM®) practice. Materials and Methods: First, using Illumina® BeadChip microarray technology, differences in global gene expression in peripheral blood mononuclear cells (PBMCs) were sought between healthy practitioners and tightly matched controls (n = 12, age 65). Second, these microarray results were verified on a subset of genes using quantitative polymerase chain reaction (qPCR) and were validated using qPCR in larger TM and control groups (n = 45, age 63). Bioinformatics investigation employed Ingenuity® Pathway Analysis (IPA®), DAVID, Genomatix, and R packages. Results: The 200 genes and loci found to meet strict criteria for differential expression in the microarray experiment showed contrasting patterns of expression that distinguished the two groups. Differential expression relating to immune function and energy efficiency were most apparent. In the TM group, relative to the control, all 49 genes associated with inflammation were downregulated, while genes associated with antiviral and antibody components of the defense response were upregulated. The largest expression differences were shown by six genes related to erythrocyte function that appeared to reflect a condition of lower energy efficiency in the control group. Results supporting these gene expression differences were obtained with qPCR-measured expression both in the well-matched microarray groups and in the larger, less well-matched groups. Conclusions: These findings are consistent with predictions based on results from earlier randomized trials of meditation and may provide evidence for stress-related molecular mechanisms underlying reductions in anxiety, post-traumatic stress disorder (PTSD), cardiovascular disease (CVD), and other chronic disorders and diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

re also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Abstract

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001870/

Meditation Strengthens Brain Attentional Networks

November 5, 2021 psyjdc Leave a comment

Meditation Strengthens Brain Attentional Networks

By John M. de Castro, Ph.D.

“meditation practice appears to positively impact attentional functions by improving resource allocation processes. As a result, attentional resources are allocated more fully during early processing phases which subsequently enhance further processing.” – Peter Malinowski

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity. Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread area. and have found that meditation practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. These brain changes with mindfulness practice are important and need to be further investigates.

Meditation practice results in a shift in mental processing. It produces a reduction of mind wandering and self-referential thinking and an increase in attention and higher-level thinking. The neural system that underlies mind wandering is termed the Default Mode Network (DMN) and consists in a set of brain structures including medial prefrontal cortex, posterior cingulate, lateral temporal cortex and the hippocampus. The neural system that underlies attention and is termed the Dorsal Attentional Network (DAN). and includes the frontal eye fields and the areas around the precentral sulcus and intraparietal sulcus. It is possible, then, that meditation over time produces changes in these brain areas improving attentional ability.

In today’s Research News article “Attention and Default Mode Network Assessments of Meditation Experience during Active Cognition and Rest.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144977/ ) Devaney and colleagues recruited experienced meditators (average of 7 years of practice) and non-meditators matched on demographic variables. The participants performed attention tasks (multiple object tracking, a sustained attention task, and oddball tasks, a sustained spatial attention task) while having their brains scanned with functional Magnetic Resonance Imaging (fMRI).

There were no significant differences between the experienced meditators and the matched controls in their performance of the attention tasks. But during the sustained attention task the meditators in comparison to the controls had increases in activation of the brain’s Dorsal Attentional Network at the same time as a significant decrease in the brain’s Default Mode Network. In addition, during the sustained attention task the meditators had significantly greater anticorrelations of activity between the two networks indicating higher levels of inhibitory activity between networks.

The Dorsal Attentional Network has been shown to be involved in focused attention. Hence, the results suggest that experience in meditation improves the response of the brain areas responsible for focused attention when needed. Alternatively, the Default Mode Network has been shown to be involved in mind wandering. Hence, the results suggest that experience in meditation reduces the response of the brain areas responsible a loss of focused attention and mind wandering when needed. Further, the results suggest that experience in meditation leads to a greater ability of the brain to focus attention while preventing mind wandering.

The fact that experienced meditators did not differ from controls in attentional task performance is a bit disappointing. But on average the meditators performed better but because of a small number of participants, the differences were not statistically significant. Perhaps with larger groups differences would be found. But the lack of statistical power makes the significant brain activation differences observed during sustained attention even more striking. This all suggests that meditation practice shapes the brain for better attentional ability.

So, meditation strengthens brain attentional network.

“Meditation is an important form of self-control and a healthy practice. It augments focus and attention and could be used to enhance empathy and all attentional capacities.” – Gabriel José Corrêa Mograbi

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Devaney, K.J.; Levin, E.J.; Tripathi, V.; Higgins, J.P.; Lazar, S.W.; Somers, D.C. Attention and Default Mode Network Assessments of Meditation Experience during Active Cognition and Rest. Brain Sci. 2021, 11, 566. https://doi.org/10.3390/ brainsci11050566

Abstract: Meditation experience has previously been shown to improve performance on behavioral assessments of attention, but the neural bases of this improvement are unknown. Two prominent, strongly competing networks exist in the human cortex: a dorsal attention network, that is activated during focused attention, and a default mode network, that is suppressed during attentionally demanding tasks. Prior studies suggest that strong anti-correlations between these networks indicate good brain health. In addition, a third network, a ventral attention network, serves as a “circuit-breaker” that transiently disrupts and redirects focused attention to permit salient stimuli to capture attention. Here, we used functional magnetic resonance imaging to contrast cortical network activation between experienced focused attention Vipassana meditators and matched controls. Participants performed two attention tasks during scanning: a sustained attention task and an attention-capture task. Meditators demonstrated increased magnitude of differential activation in the dorsal attention vs. default mode network in a sustained attention task, relative to controls. In contrast, there were no evident attention network differences between meditators and controls in an attentional reorienting paradigm. A resting state functional connectivity analysis revealed a greater magnitude of anticorrelation between dorsal attention and default mode networks in the meditators as compared to both our local control group and a n = 168 Human Connectome Project dataset. These results demonstrate, with both task- and rest-based fMRI data, increased stability in sustained attention processes without an associated attentional capture cost in meditators. Task and resting-state results, which revealed stronger anticorrelations between dorsal attention and default mode networks in experienced mediators than in controls, are consistent with a brain health benefit of long-term meditation practice.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144977/

Better Mental Health During the Covid-19 Pandemic is Associated with Exercise and Meditation

November 4, 2021 psyjdc Leave a comment

Better Mental Health During the Covid-19 Pandemic is Associated with Exercise and Meditation

By John M. de Castro, Ph.D.

“Introducing a mindfulness and meditation practice during this pandemic has the potential to complement treatment and is a low-cost beneficial method of providing support with anxiety for all.” C. Behan

Mindfulness training has been shown to improve health and well-being in healthy individuals. It has also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. The COVID-19 pandemic has challenged the mental and physical health of the population. It has created intense stress both for frontline workers but also for people simply isolating at home. Mindfulness is known to decrease the psychological and physical responses to stress. So, meditation may be helpful in coping with the mental and physical challenges resulting from the COVID-19 pandemic.

In today’s Research News article “The Effect of Meditation and Physical Activity on the Mental Health Impact of COVID-19-Related Stress and Attention to News Among Mobile App Users in the United States: Cross-sectional Survey.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045775/ ) Green and colleagues recruited adult participants online who used the meditation app “Calm” and had them complete a questionnaire measuring worry regarding Covid-19, meditation, exercise, and health related behaviors. They also had them complete measures of habits, perceived stress, anxiety, depression, and PTSD symptoms.

There were 8,392 responses. They reported a significant increase in meditation and exercise during Covid-19. But the greater the worry about Covid-19, the lower the levels of meditation and exercise and the greater the levels of perceived stress and PTSD symptoms. They found that the Covid-19 worry was associated with lower the levels of meditation and exercise and these decreases were in turn associated with higher levels of perceived stress, PTSD symptoms, anxiety and depression. Hence, worry about Covid-19 appears to be detrimental to mental health as a result of decreases meditation and exercise.

These results are correlational, and caution must be exercised in concluding causation. In addition, the sample was composed of users of a meditation app and thus the results may not be predictive of the responses of non-meditators. But the associations are clear. Worry about the pandemic is associated with decreases in meditation and exercise which are in turn associated with poorer mental health.

This suggests that methods to support continued meditation practice and exercise during the pandemic may be helpful in improving mental health during the pandemic. They may mitigate the detrimental effects of worry about the pandemic. Indeed, previous research has found that mindfulness training improves mental health during the Covid-19 pandemic.

So, better mental health during the covid-19 pandemic is associated with exercise and meditation.

“certain meditation, yoga asana (postures), and pranayama (breathing) practices may possibly be effective adjunctive means of treating and/or preventing SARS-CoV-2 infection” – William Bushell

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Green, J., Huberty, J., Puzia, M., & Stecher, C. (2021). The Effect of Meditation and Physical Activity on the Mental Health Impact of COVID-19-Related Stress and Attention to News Among Mobile App Users in the United States: Cross-sectional Survey. JMIR mental health, 8(4), e28479. https://doi.org/10.2196/28479

Abstract

Background

The COVID-19 pandemic has been declared an international public health emergency, and it may have long-lasting effects on people’s mental health. There is a need to identify effective health behaviors to mitigate the negative mental health impact of COVID-19.

Objective

The objectives of this study were to (1) examine the regional differences in mental health and COVID-19–related worry, attention to news, and stress, in light of the state-level prevalence of COVID-19 cases; (2) estimate the associations between mental health and COVID-19–related worry, attention to news, and stress and health behavior engagement (ie, physical activity, mindfulness meditation); and (3) explore the mediating effect of health behavior engagement on the associations between mental health and COVID-19–related worry, attention to news, and stress.

Methods

A cross-sectional survey was distributed to a sample of US adult paying subscribers to the Calm app (data were collected from April 22 to June 3, 2020). The survey assessed COVID-19–related worry, attention to news, and stress; health behavior engagement; and mental health (ie, perceived stress, posttraumatic stress disorder, and anxiety and depression). Statistical analyses were performed using R software. Differences in COVID-19–related worry, attention to news, and stress and mental health by location were assessed using t tests and chi-square tests. Logistic and ordinary least squares models were used to regress mental health and health behavior on COVID-19–related worry, attention to news, and stress; moreover, causal mediation analysis was used to estimate the significance of the mediation effects.

Results

The median age of the respondents (N=8392) was 47 years (SD 13.8). Participants in the Mid-Atlantic region (New Jersey, New York, and Pennsylvania) reported higher levels of stress, more severe depression symptoms, greater worry about COVID-19, paying more attention to COVID-19–related news, and more stress related to social distancing recommendations than participants living in other regions. The association between worry about COVID-19 and perceived stress was significantly mediated by changes in physical activity (P<.001), strength of meditation habit (P<.001), and stopping meditation (P=.046). The association between worry about COVID-19 and posttraumatic stress disorder symptoms was significantly mediated by changes in physical activity (P<.001) and strength of meditation habit (P<.001).

Conclusions

Our findings describe the mental health impact of COVID-19 and outline how continued participation in health behaviors such as physical activity and mindfulness meditation reduce worsening of mental health due to the COVID-19 pandemic. These data have important implications for public health agencies and health organizations to promote the maintenance of health habits to reduce the residual mental health burden of the COVID-19 pandemic.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045775/

Improve Military-Related Post Traumatic Stress Disorder (PTSD) with Mindfulness

November 3, 2021 psyjdc Leave a comment

Improve Military-Related Post Traumatic Stress Disorder (PTSD) with Mindfulness

By John M. de Castro, Ph.D.

“mindfulness may help to mitigate the relationship between maladaptive thinking and posttraumatic distress.” – Matthew Tull

Experiencing trauma is quite common. It has been estimated that 60% of men and 50% of women will experience a significant traumatic event during their lifetime. But only a fraction will develop Post-Traumatic Stress Disorder (PTSD). But this still results in a frightening number of people with 7%-8% of the population developing PTSD at some point in their life. For military personnel, it’s much more likely for PTSD to develop with about 11%-20% of those who have served in a war zone developing PTSD.

PTSD involves a number of troubling symptoms including reliving the event with the same fear and horror in nightmares or with a flashback. PTSD sufferers avoid situations that remind them of the event this may include crowds, driving, movies, etc. and may avoid seeking help because it keeps them from having to think or talk about the event. They often experience negative changes in beliefs and feelings including difficulty experiencing positive or loving feelings toward other people, avoiding relationships, memory difficulties, or see the world as dangerous and no one can be trusted. Sufferers may feel hyperarousal, feeling keyed up and jittery, or always alert and on the lookout for danger. They may experience sudden anger or irritability, may have a hard time sleeping or concentrating, may be startled by a loud noise or surprise.

Obviously, these are troubling symptoms that need to be addressed. There are a number of therapies that have been developed to treat Post-Traumatic Stress Disorder (PTSD). Mindfulness-based therapies have been shown to be particularly effective in treating PTSD. There has accumulated a considerable amount of research. So, it is important to step back and summarize what has been learned.

In today’s Research News article “Military-related posttraumatic stress disorder and mindfulness meditation: A systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344114/ ) Sun and colleagues review summarize and perform a meta-analysis of the published randomized controlled trials on the effectiveness of mindfulness practice to improve the symptoms of PTSD.

They identified 19 published randomized controlled trials with a total of 1326 participants, 15 of which employed an active control condition. They report that the published research found that mindfulness meditation practices produced a significant reduction in the symptoms of military-related Post-Traumatic Stress Disorder (PTSD). This improvement was present regardless of the nature of the control condition, whether the treatment was provided individually or in a group, or the duration of the therapy. Hence, the published research studies support the conclusion that mindfulness meditation practice is a safe and effective treatment for the symptoms of PTSD in military personnel.

So, improve military-related Post Traumatic Stress Disorder (PTSD) with mindfulness.

CMCS – Center for Mindfulness and Contemplative Studies

“research has shown mindfulness to be helpful with other anxiety problems. It has also been shown to help with symptoms of PTSD, such as avoidance and hyperarousal.” – National Center for PTSD

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Sun, L. N., Gu, J. W., Huang, L. J., Shang, Z. L., Zhou, Y. G., Wu, L. L., Jia, Y. P., Liu, N. Q., & Liu, W. Z. (2021). Military-related posttraumatic stress disorder and mindfulness meditation: A systematic review and meta-analysis. Chinese journal of traumatology = Zhonghua chuang shang za zhi, 24(4), 221–230. https://doi.org/10.1016/j.cjtee.2021.05.003

Abstract

Purpose

Posttraumatic stress disorder (PTSD) is a significant global mental health concern, especially in the military. This study aims to estimate the efficacy of mindfulness meditation in the treatment of military-related PTSD, by synthesizing evidences from randomized controlled trials.

Methods

Five electronic databases (Pubmed, EBSCO Medline, Embase, PsychINFO and Cochrane Library) were searched for randomized controlled trials focusing on the treatment effect of mindfulness meditation on military-related PTSD. The selection of eligible studies was based on identical inclusion and exclusion criteria. Information about study characteristics, participant characteristics, intervention details, PTSD outcomes, as well as potential adverse effects was extracted from the included studies. Risk of bias of all the included studies was critically assessed using the Cochrane Collaboration’s tool. R Statistical software was performed for data analysis.

Results

A total of 1902 records were initially identified and screened. After duplicates removal and title & abstract review, finally, 19 articles in English language with 1326 participants were included through strict inclusion and exclusion criteria. The results revealed that mindfulness meditation had a significantly larger effect on alleviating military-related PTSD symptoms compared with control conditions, such as treatment as usual, present-centered group therapy and PTSD health education (standardized mean difference (SMD) = −0.33; 95% CI [−0.45, −0.21]; p < 0.0001). Mindfulness interventions with different control conditions (active or non-active control, SMD = −0.33, 95% CI [−0.46, −0.19]; SMD = −0.49, 95% CI [−0.88, −0.10], respectively), formats of delivery (group-based or individual-based, SMD = −0.30, 95% CI [−0.42, −0.17], SMD = −0.49, 95% CI [−0.90, −0.08], respectively) and intervention durations (short-term or standard duration, SMD = −0.27, 95% CI [−0.46, −0.08], SMD = −0.40, 95% CI [−0.58, −0.21], respectively) were equally effective in improving military-related PTSD symptoms.

Conclusion

Findings from this meta-analysis consolidate the efficacy and feasibility of mindfulness meditation in the treatment of military-related PTSD. Further evidence with higher quality and more rigorous design is needed in the future.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344114/

Reduce Oxidative Stress with Tai Chi

November 2, 2021 psyjdc Leave a comment

Reduce Oxidative Stress with Tai Chi

By John M. de Castro, Ph.D.

“Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. Oxidative stress occurs naturally and plays a role in the aging process.” – Jamie Eske

Free radicals are oxidants that need to be balanced with antioxidants. If there is an imbalance in the cells and the blood it produces a condition known as oxidative stress that has been associated with neurodegenerative diseases, gene mutations and cancers, chronic fatigue syndrome, fragile X syndrome, heart and blood vessel disorders, atherosclerosis, heart failure, heart attack and inflammatory diseases. So, there is a need for treatments to reduce oxidative stress. Yoga practice is an exercise and a mindfulness practice that produces a significant increase in blood antioxidants, reducing oxidative stress. Mindful movement practices such as Tai Chi and Qigong are also exercises and mindfulness practices. It is interesting to investigate whether these practices are also effective in reducing oxidative stress.

In today’s Research News article “Effect of Tai Chi on Markers of Oxidative Stress: Systematic Review and Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037964/ ) Rosado-Pérez and colleagues review, summarize, and perform a meta-analysis of the published research studies of the effects of Tai Chi practice on oxidative stress.

They identified 10 published research studies 5 of which were randomized controlled trials. They contained a total of 621 participants. Oxidative stress involves a number of markers in the blood. They report that the published studies found that Tai Chi practice resulted in a significant increase in antioxidant enzymes superoxide dismutase and catalase, and a significant decrease in the levels of lipoperoxides. So, Tai Chi practice reduced oxidative stress.

Tai Chi practice is both a mindfulness training and an exercise. The published studies did not compare Tai Chi to other exercises. So, it cannot be determined if the observed reduction in oxidative stress markers produced by Tai Chi practice was due to which component or both. Regardless, it is clear that Tai Chi practice reduces oxidative stress. This may be one of the underlying mechanisms by which Tai Chi improves the health and well-being of practitioners.

So, reduce oxidative stress with Tai Chi.

CMCS – Center for Mindfulness and Contemplative Studies

“One year of Tai Chi training has been reported to promote superoxide dismutase activity and lessen lipid peroxidation.” – Chitrawina Mahagita

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Rosado-Pérez, J., Castelán-Martínez, O. D., Mújica-Calderón, A. J., Sánchez-Rodríguez, M. A., & Mendoza-Núñez, V. M. (2021). Effect of Tai Chi on Markers of Oxidative Stress: Systematic Review and Meta-Analysis. International journal of environmental research and public health, 18(7), 3458. https://doi.org/10.3390/ijerph18073458

Abstract

Background: This study aimed to synthesize the evidence of the effect of practicing Tai Chi on oxidative stress markers (OxSM). Methods: This systematic review and meta-analysis was conducting using the MEDLINE, Cochrane Library, ScienceDirect, Scopus, Epistemonikos, Lilacs, and Ovid databases to identify randomized (RCT) and non-randomized (NRCT) clinical trials that evaluated the Tai Chi effect on OxSM compared to sedentary behavior, walking or yoga. Pooled mean differences (MDs) with 95% confidence intervals (95%CI) were estimated using the inverse variance method to determine the effect of Tai Chi on OxSM. PROSPERO register: CRD42019138362. Results: Five RCT and five NRCT were included. Compared to sedentary behavior, regular Tai Chi practice increases the levels of the enzymes superoxide dismutase (MD = 34.97 U/mL, (95%CI, 9.45 to 60.48), 344 participants) and catalase (MD = 15.63 U/mL, (95%CI, 4.05 to 27.22), 110 participants), as well as reducing the levels of lipoperoxides (MD = −0.02 µmol/L, (95%CI, −0.04 to −0.00), 234 participants). For comparisons with walking or yoga, only one study per activity was identified comparing the effect on OxSM. Conclusions: Regular Tai Chi practice increases the levels of superoxide dismutase and catalase, as well as reducing the levels of lipoperoxides. More studies are necessary to determine the effect of Tai Chi on OxSM when compared to other physical activities.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037964/

Reduce Self-Harm and Suicidality in Adolescents with Mindfulness

November 1, 2021 psyjdc Leave a comment

Reduce Self-Harm and Suicidality in Adolescents with Mindfulness

By John M. de Castro, Ph.D.

“growing evidence supports DBT-A as a likely viable treatment intervention for adolescents who self-harm.” – Kimberly R. Freeman

Around 43,000 people take their own lives each year in the US. The problem is far worse than these statistics suggest as it has been estimated that for every completed suicide there were 12 unsuccessful attempts. In other words, about a half a million people in the U.S. attempt suicide each year. Indeed, suicide is the second leading cause of death in adolescents.

Self-injury is a disturbing phenomenon occurring worldwide, especially in developed countries, such as the U.S. and those in western Europe. Approximately two million cases are reported annually in the U.S. Each year, 1 in 5 females and 1 in 7 males engage in self-injury usually starting in the teen years.

One of the few treatments that appears to be Dialectical Behavior Therapy (DBT). It is targeted at changing the problem behaviors characteristic including self-injury. Behavior change is accomplished through focusing on changing the thoughts and emotions that precede problem behaviors, as well as by solving the problems faced by individuals that contribute to problematic thoughts, feelings and behaviors. In DBT five core skills are practiced; mindfulness, distress tolerance, emotion regulation, the middle path, and interpersonal effectiveness. DBT has been found to reduce self-injurious behaviors. The data is accumulating so there is a need to review and summarize what has been found.

In today’s Research News article “Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188531/ ) Kothgassner and colleagues review, summarize, and perform a meta-analysis of the published research literature on the effectiveness of Dialectical Behavior Therapy (DBT) for the treatment of self-harm and suicidality in adolescents.

They identified 21 published research studies encompassing 1673 adolescents. They report that the published research found that Dialectical Behavior Therapy (DBT) resulted in significant reductions in self-harm and suicide ideation in the adolescents. They further found that the longer the duration of DBT treatment the greater the reductions in suicidal ideation.

This summary of the published research studies suggests that Dialectical Behavior Therapy (DBT) is a safe and effective treatment for the reduction of self-harm and suicidal thoughts in adolescents. Since, suicide is the second leading cause of death in adolescents and has increased substantially over the last decade, a treatment that can help reduce these rates is needed. The present results suggest that DBT with its associated training in mindfulness may be able to address this need.

So, reduce self-harm and suicidality in adolescents with mindfulness.

“the DBT-A group experienced fewer episodes of self-harm. . . as well as statistically significant reductions in suicidal ideation and depression (both of which are risk factors for suicide).” – Suicide Prevention Resource Center

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Kothgassner, O. D., Goreis, A., Robinson, K., Huscsava, M. M., Schmahl, C., & Plener, P. L. (2021). Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis. Psychological medicine, 51(7), 1057–1067. https://doi.org/10.1017/S0033291721001355

Abstract

Background

Given the widespread nature and clinical consequences of self-harm and suicidal ideation among adolescents, establishing the efficacy of developmentally appropriate treatments that reduce both self-harm and suicidal ideation in the context of broader adolescent psychopathology is critical.

Methods

We conducted a systematic review and meta-analysis of the Dialectical Behaviour Therapy for Adolescents (DBT-A) literature on treating self-injury in adolescents (12–19 years). We searched for eligible trials and treatment evaluations published prior to July 2020 in MEDLINE/PubMed, Scopus, Google Scholar, EMBASE, and the Cochrane Library databases for clinical trials. Twenty-one studies were identified [five randomized-controlled trials (RCTs), three controlled clinical trials (CCTs), and 13 pre-post evaluations]. We extracted data for predefined primary (self-harm, suicidal ideation) and secondary outcomes (borderline personality symptoms; BPD) and calculated treatment effects for RCTs/CCTs and pre-post evaluations. This meta-analysis was pre-registered with OSF: osf.io/v83e7.

Results

Overall, the studies comprised 1673 adolescents. Compared to control groups, DBT-A showed small to moderate effects for reducing self-harm (g = −0.44; 95% CI −0.81 to −0.07) and suicidal ideation (g = −0.31, 95% CI −0.52 to −0.09). Pre-post evaluations suggested large effects for all outcomes (self-harm: g = −0.98, 95% CI −1.15 to −0.81; suicidal ideation: g = −1.16, 95% CI −1.51 to −0.80; BPD symptoms: g = −0.97, 95% CI −1.31 to −0.63).

Conclusions

DBT-A appears to be a valuable treatment in reducing both adolescent self-harm and suicidal ideation. However, evidence that DBT-A reduces BPD symptoms was only found in pre-post evaluations.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188531/

Improve the Well-Being of Children with Special Health Care Needs and Their Parents with Mindfulness

October 29, 2021 psyjdc Leave a comment

Improve the Well-Being of Children with Special Health Care Needs and Their Parents with Mindfulness

By John M. de Castro, Ph.D.

“mindfulness-based parenting program can be an effective intervention for reducing the stress experienced by parents of children with special needs.” – Elizabeth J. Shaffer

There is a tremendous demand for caregiving in the US. It is estimated that over 65 million (29% of the adult population) provides care to someone who is ill, disabled, or aged, averaging 20 hours per week spent caring for their loved ones. Children with special health care needs include a variety of conditions from psychological such as anxiety disorders or depression to chronic conditions such as asthma or diabetes or chronic pain, to developmental issues such as autism. They place considerable burdens on their caregivers. Mindfulness practice for caregivers has been shown to help them cope with the physical and psychological demands of caregiving.

A therapeutic technique that contains mindfulness training and Cognitive Behavioral Therapy (CBT) is Acceptance and Commitment Therapy (ACT). It focuses on the individual’s thoughts, feelings, and behavior and how they interact to impact their psychological and physical well-being. It then works to change thinking to alter the interaction and produce greater life satisfaction. ACT employs mindfulness practices to increase awareness and develop an attitude of acceptance and compassion in the presence of painful thoughts and feelings. ACT teaches individuals to “just notice”, accept and embrace private experiences and focus on behavioral responses that produce more desirable outcomes.

There has been accumulating research on the application of Acceptance and Commitment Therapy (ACT) for the treatment of children with special health care needs and their caregivers and there is a need to review and summarize the findings. In today’s Research News article “Acceptance and Commitment Therapy for Children with Special Health Care Needs and Their Parents: A Systematic Review and Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345967/ ) Parmar and colleagues review, summarize, and perform a meta-analysis of the published research studies on the effectiveness of Acceptance and Commitment Therapy (ACT) for the treatment of children with special health care needs and their caregivers.

They identified 10 published research studies. They report that the published research finds that Acceptance and Commitment Therapy (ACT) produces significant reductions in depression and perceived stress, and increases in psychological flexibility in the children. On the other hand, the parents did not show similar improvements except for a small improvement in psychological flexibility.

The published research, then, suggests that Acceptance and Commitment Therapy (ACT) is effective for children with special health care needs in reducing mental distress and increasing their flexibility in dealing with it. ACT also produce small improvements in their caregivers. This suggests that ACT should be recommended to increase mindfulness in children with special health care needs to improve their psychological well-being.

CMCS – Center for Mindfulness and Contemplative Studies

“cultivating a more mindful way of parenting is associated with reduced stress, anxiety, and depression. Parents experienced increased mindful awareness and improved psychological well-being, and they were more accepting of their children. Their children also had fewer behavior problems and enhanced positive interaction with their parents.” – Manika Petcharat

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Parmar, A., Esser, K., Barreira, L., Miller, D., Morinis, L., Chong, Y. Y., Smith, W., Major, N., Church, P., Cohen, E., & Orkin, J. (2021). Acceptance and Commitment Therapy for Children with Special Health Care Needs and Their Parents: A Systematic Review and Meta-Analysis. International journal of environmental research and public health, 18(15), 8205. https://doi.org/10.3390/ijerph18158205

Abstract

Context: Acceptance and Commitment Therapy (ACT) is an emerging treatment for improving psychological well-being. Objective: To summarize research evaluating the effects of ACT on psychological well-being in children with special health care needs (SHCN) and their parents. Data Sources: An electronic literature search was conducted in PubMed, Web of Science, Ovid/EMBASE and PsycINFO (January 2000–April 2021). Study Selection: Included were studies that assessed ACT in children with SHCN (ages 0–17y) and/or parents of children with SHCN and had a comparator group. Data Extraction: Descriptive data were synthesized and presented in a tabular format, and data on relevant outcomes (e.g., depressive symptoms, stress, avoidance and fusion) were used in the meta-analyses to explore the effectiveness of ACT (administered independently with no other psychological therapy) compared to no treatment. Results: Ten studies were identified (child (7) and parent (3)). In children with SHCN, ACT was more effective than no treatment at helping depressive symptoms (standardized mean difference [SMD] = −4.27, 95% CI: −5.20, −3.34; p < 0.001) and avoidance and fusion (SMD = −1.64, 95% CI: −3.24, −0.03; p = 0.05), but not stress. In parents of children with SHCN, ACT may help psychological inflexibility (SMD = −0.77, 95% CI: −1.07, −0.47; p < 0.01). Limitations: There was considerable statistical heterogeneity in three of the six meta-analyses. Conclusions: There is some evidence that ACT may help with depressive symptoms in children with SHCN and psychological inflexibility in their parents. Research on the efficacy of ACT for a variety of children with SHCN and their parents is especially limited, and future research is needed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345967/

Improve Posttraumatic Stress Disorder (PTSD) with Mindfulness

October 28, 2021 psyjdc Leave a comment

Improve Posttraumatic Stress Disorder (PTSD) with Mindfulness

By John M. de Castro, Ph.D.

“As a clinical psychologist working at the VA, I found that veterans who also had a practice, whether it be meditation or mindful movement, had better outcomes,” – Dan Libby

Obviously, these are troubling symptoms that need to be addressed. There are a number of therapies that have been developed to treat PTSD. One of which, mindfulness training has been found to be particularly effective. The Mindfulness-based Stress reduction (MBSR) program involves meditation, yoga, body scan and group discussion. It has been found to improve the symptoms of PTSD.

In today’s Research News article “A Multisite Randomized Controlled Trial of Mindfulness-Based Stress Reduction in the Treatment of Posttraumatic Stress Disorder.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189576/ ) Davis and colleagues recruited veterans who were diagnosed with Post-Traumatic Stress Disorder (PTSD) and randomly assigned them to receive 8 weeks of Mindfulness-based Stress reduction (MBSR) or Present-Centered Group Therapy (PCGT). PCGT was a control condition that contained many of the non-specific, social effects and expectations contained in MBSR, but discussions were on current events and everyday problems but not trauma. They were measured before and after treatment and 7 weeks later for PTSD symptoms, mindfulness, and health.

They found that at the 7-week follow up assessment both groups had significant reductions in PTSD severity as assessed in a clinical interview and increases in mindfulness and did not statistically differ. For both groups the greater the increase in mindfulness that occurred over treatment the greater the reductions in clinically assessed PTSD severity. On the other hand, there were significantly greater reductions in self-reported PTSD symptoms in the MBSR group.

It is surprising that Present-Centered Group Therapy (PCGT) produced such significant improvements. This demonstrates the power of non-specific factors in therapy. Factors such as “decreased isolation, shared support, shared positive experiences with other veterans with similar symptoms, experience of an atmosphere of safety, and awareness and objectivity of how PTSD affects one’s daily life” produce major improvements in PTSD. In most research the control condition doesn’t contain these components and as a result the intervention effects appear quite large.

But even with the strong control condition employed here, Mindfulness-based Stress reduction (MBSR) produced significantly greater improvements in the veterans self-assessments of their symptoms. One of the reasons that Present-Centered Group Therapy (PCGT) produced significant improvements is that it increased mindfulness. It has been previously found that increases in mindfulness produces improvements in the symptoms of PTSD. So, increasing mindfulness, no matter what technique accomplishes it, may be the key to improving the symptoms of PTSD.

So, improve Posttraumatic Stress Disorder (PTSD) with mindfulness.

“Both MBSR and present-centered group therapy appear to have beneficial effects in treating PTSD in veterans, with greater improvement observed in self-reported PTSD symptoms among the MBSR group.” – Mitch Mirkin

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Davis, L. L., Whetsell, C., Hamner, M. B., Carmody, J., Rothbaum, B. O., Allen, R. S., Al Bartolucci, A., Southwick, S. M., & Bremner, J. D. (2019). A Multisite Randomized Controlled Trial of Mindfulness-Based Stress Reduction in the Treatment of Posttraumatic Stress Disorder. Psychiatric research and clinical practice, 1(2), 39–48. https://doi.org/10.1176/appi.prcp.20180002

Abstract

Objective:

Posttraumatic stress disorder (PTSD) is often difficult to treat, and many patients do not achieve full remission. Complementary and integrative health approaches, such as mindfulness meditation, are intended to be integrated with evidence-based treatment. This study examined the efficacy of mindfulness-based stress reduction (MBSR) in the treatment of PTSD in U.S. military veterans.

Methods:

Veterans with a diagnosis of PTSD (N=214) were randomly assigned to either 90-minute group MBSR or present-centered group therapy (PCGT) for eight weeks. Follow-up assessments were obtained at baseline and weeks 3, 6, 9 (primary endpoint), and 16.

Results:

Both the MBSR and PCGT groups achieved significant improvement in PTSD as measured by the Clinician-Administered PTSD Scale for DSM-IV (CAPS-IV), with no statistically significant differences between groups. However, compared with PCGT, the MBSR group showed a statistically significant improvement in PTSD on the self-reported PTSD Checklist for DSM-IV over the nine weeks. This difference was not maintained posttreatment, at week 16. Strengths of the study include its large sample size, multisite design, active control group, single-blind outcome ratings, fidelity monitoring, large minority representation, and randomized approach. The study was limited by its high attrition rate and low representation of women.

Conclusion:

Both MBSR and PCGT appear to have beneficial effects in treating PTSD in veterans, with greater improvement observed in self-reported PTSD symptoms in the MBSR group. No differences between groups were observed on the CAPS-IV scale.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8189576/

Improve Lipid Metabolism in Diabetes with Yoga

October 27, 2021 psyjdc Leave a comment

Improve Lipid Metabolism in Diabetes with Yoga

By John M. de Castro, Ph.D.

“Yoga, being a lifestyle incorporating exercise and stress management training, targets the elevated lipid levels in patients with diabetes.” – Nisha Shantakumari

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes and the numbers are growing. Type II Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

Type 2 diabetes is a common and increasingly prevalent illness that is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary lifestyle. Unlike Type I Diabetes, Type II does not require insulin injections. Instead, the treatment and prevention of Type 2 Diabetes focuses on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. A mindfulness practice that combines mindfulness with exercise is yoga and it has been shown to be helpful in the treatment of Type II Diabetes.

In today’s Research News article “Effectiveness of Yoga Lifestyle on Lipid Metabolism in a Vulnerable Population-A Community Based Multicenter Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303653/ ) Nagarathna and colleagues recruited a large nationwide rural and urban based sample of adults with no diabetes, prediabetes (high risk for development of Type 2 diabetes), or type 2 diabetes and randomly assigned them to receive either standard lifestyle treatment with lectures on diet, exercise, sleep and stress management or the same lifestyle treatment plus 3 months of daily, 60 minute, yoga practice consisting of postures, breathing practices, relaxation, pranayama, meditation. Blood was drawn before and after treatment and assayed for lipids.

They found that in comparison to baseline and the control group, the yoga group after training had significantly lower levels of blood total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein. This was true particularly for participants with high baseline blood lipid levels. These improvements were present for both males and females, for urban and rural participants, and for younger (<40 years of age) and older (>40) praticipants.

This study examined a very large nationwide community sample (>10,000) participants and is thus highly generalizable. It replicates previous research demonstrating the ability of yoga practice reduce blood fat levels and to improves patients with diabetes. But yoga is both a contemplative practice and an exercise. The control condition in this study did not contain exercise. So, it is impossible to tell if the improvements occurred due to yoga practice or to the exercise provided in the practice. Future studies should contain an alternative exercise control condition.

Regardless, it is clear that yoga practice improves blood lipid profiles in prediabetic and diabetic adults. This should help to restrain or delay the secondary health problems that are associated with diabetes. This should improve the quality of life, health, and well-being of the individuals.

So, improve lipid metabolism in diabetes with yoga.

“Yoga can do more than just relax your body in mind — especially if you’re living with diabetes. Certain poses may help lower blood pressure and blood sugar levels while also improving circulation, leading many experts to recommend yoga for diabetes management.” – Emily Cronkleton

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Nagarathna, R., Kumar, S., Anand, A., Acharya, I. N., Singh, A. K., Patil, S. S., Latha, R. H., Datey, P., & Nagendra, H. R. (2021). Effectiveness of Yoga Lifestyle on Lipid Metabolism in a Vulnerable Population-A Community Based Multicenter Randomized Controlled Trial. Medicines (Basel, Switzerland), 8(7), 37. https://doi.org/10.3390/medicines8070037

Abstract

Background: Dyslipidemia poses a high risk for cardiovascular disease and stroke in Type 2 diabetes (T2DM). There are no studies on the impact of a validated integrated yoga lifestyle protocol on lipid profiles in a high-risk diabetes population. Methods: Here, we report the results of lipid profile values of 11,254 (yoga 5932 and control 5322) adults (20–70 years) of both genders with high risk (≥60 on Indian diabetes risk score) for diabetes from a nationwide rural and urban community-based two group (yoga and conventional management) cluster randomized controlled trial. The yoga group practiced a validated integrated yoga lifestyle protocol (DYP) in nine day camps followed by daily one-hour practice. Biochemical profiling included glycated hemoglobin and lipid profiles before and after three months. Results: There was a significant difference between groups (p < 0.001 ANCOVA) with improved serum total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein in the yoga group compared to the control group. Further, the regulatory effect of yoga was noted with a significant decrease or increase in those with high or low values of lipids, respectively, with marginal or no change in those within the normal range. Conclusion: Yoga lifestyle improves and regulates (lowered if high, increased if low) the blood lipid levels in both genders of prediabetic and diabetic individuals in both rural and urban Indian communities.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303653/