Mindfulness-Based Therapies Reduce Migraine Frequency and Disability

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How Can Mindfulness Meditation Help with Migraines? | The Mindfulness Meditation Institute

By John M. de Castro, Ph.D.

 

In today’s Research News article “Behavioral interventions for migraine prevention: A systematic review and meta-analysis” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11951403/ ) Treadwell and colleagues review, summarize, and perform a meta-analysis of the published research on the effectiveness of mindfulness-based therapies for the treatment of migraine headaches. They report that the research indicates that mindfulness-based therapies are effective in reducing the frequency of migraine headaches and the disability produced by the headaches.

 

Treat migraines with mindfulness.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Treadwell JR, Tsou AY, Rouse B, Ivlev I, Fricke J, Buse DC, Powers SW, Minen M, Szperka CL, Mull NK. Behavioral interventions for migraine prevention: A systematic review and meta-analysis. Headache. 2025 Apr;65(4):668-694. doi: 10.1111/head.14914. Epub 2025 Feb 19. PMID: 39968795; PMCID: PMC11951403.

Abstract

Objectives/Background

This study was undertaken to synthesize evidence on the benefits and harms of behavioral interventions for migraine prevention in children and adults. The efficacy and safety of behavioral interventions for migraine prevention have not been tested in recent systematic reviews.

Methods

An expert panel including clinical psychologists, neurologists, primary care physicians, researchers, funders, individuals with migraine, and their caregivers informed the scope and methods. We searched MEDLINE, Embase, PsycINFO, PubMed, the Cochrane Database of Systematic Reviews, clinicaltrials.gov, and gray literature for English‐language randomized trials (January 1, 1975 to August 24, 2023) of behavioral interventions for preventing migraine attacks. Primary outcomes were migraine/headache frequency, migraine disability, and migraine‐related quality of life. One reviewer extracted data and rated the risk of bias, and a second verified data for completeness and accuracy. Data were synthesized with meta‐analysis when deemed appropriate, and we rated the strength of evidence (SOE) using established methods.

Results

For adults, we included 50 trials (77 publications, N = 6024 adults). Most interventions were multicomponent (e.g., cognitive behavioral therapy [CBT], biofeedback, relaxation training, mindfulness‐based therapies, and/or education). Most trials were at high risk of bias, primarily due to possible measurement bias and incomplete data. For adults, we found that any of three components (CBT, relaxation training, mindfulness‐based therapies) may reduce migraine/headache attack frequency (SOE: low). Education alone that targets behavior may improve migraine‐related disability (SOE: low). For three other interventions (biofeedback, acceptance and commitment therapy, and hypnotherapy), evidence was insufficient to permit conclusions. We also found that mindfulness‐based therapies may reduce migraine disability more than education, and relaxation + education may improve migraine‐related quality of life more than propranolol (SOE: low). For children/adolescents, we included 13 trials (16 publications, N = 1444 children), but the evidence was only sufficient to conclude that CBT + biofeedback + relaxation training may reduce migraine attack frequency and disability more than education alone (SOE: low).

Conclusion

Results suggest that for adults, CBT, relaxation training, and mindfulness‐based therapies may each reduce the frequency of migraine/headache attacks, and education alone may reduce disability. For children/adolescents, CBT + biofeedback + relaxation training may reduce migraine attack frequency and disability more than education alone. Evidence consisted primarily of underpowered trials of multicomponent interventions compared with various types of control groups. Limitations include semantic inconsistencies in the literature since 1975, differential usage of treatment components, expectation effects for subjectively reported outcomes, incomplete data, and unclear dosing effects. Future research should enroll children and adolescents, standardize intervention components when possible to improve reproducibility, consider smart study designs and personalized therapies based on individual characteristics, use comparison groups that control for expectation, which is a known challenge in behavioral trials, enroll and retain larger samples, study emerging digital and telehealth modes of care delivery, improve the completeness of data collection, and establish or update clinical trial conduct and reporting guidelines that are appropriate for the conduct of studies of behavioral therapies.

 

Tai Chi and Qigong Improve COPD

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Tai Chi could improve quality of life for people living with COPD - European Lung Foundation

By John M. de Castro, Ph.D.

 

In today’s Research News article “Effect of Tai Ji and/or Qigong on patients with stable chronic obstructive pulmonary disease: A meta-analysis and systematic review” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11789891/ ) Liu and Cheng review and summarize the published research studies on the effectiveness of Tai Chi and Qigong practices for the treatment of Chronic obstructive pulmonary disease (COPD). They report that the published research found that these practices improve respiration in stable COPD patients and promote improves Quality of Life in these patients.

 

So, treat chronic obstructive pulmonary disease (COPD) with Tai Chi and Qigong.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu H, Cheng N. Effect of Tai Ji and/or Qigong on patients with stable chronic obstructive pulmonary disease: A meta-analysis and systematic review. Medicine (Baltimore). 2025 Jan 31;104(5):e41390. doi: 10.1097/MD.0000000000041390. PMID: 39889182; PMCID: PMC11789891.

 

Abstract

Background:

Chronic obstructive pulmonary disease (COPD) is a global health problem with high morbidity and mortality. Tai Ji and Qigong are traditional Chinese meditative movements, benefit COPD patient’s physical and mental health.

Methods:

We searched the following 7 databases Web of Science, EBSCO, Medline, PubMed, CINAHL, Cochrane Library online, and CNKI from inception to July 2023. Any RCTs managed with Tai Ji and/or Qigong on stable COPD were eligible without age, and comparison management restrict, however should be published in English. Outcome measures comprised pulmonary function, 6WMT, physical and/or cognitive function, and any assessment of people QoL.

Results:

Tai Ji and/or Qigong significant increased %PredFEV1 on stable COPD people (MD: 3.46, 95% CI: 1.69–5.23), and 6MWT (MD: 45.07, 95% CI: 31.16–58.97). 5/6 studies reported a meaningful change in CAT/SGRQ total (MD: −4.04, 95% CI: −7.76 to −0.32; MD: −11.95, 95% CI: −21.22 to −2.68). However, 6MWT, CAT and SGRO total were debated on high heterogeneity.

Conclusion:

Tai Ji and Qigong increase %PredFEV1 and promote QoL. However, the evidences are not sufficient, a proper subgroup analysis should be considered.

 

Spirituality of Science

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Fritjof Capra on Science and Spirituality

By John M. de Castro, Ph.D.

 

In today’s Research News article “Spirituality of Science: Implications for Meaning, Well-Being, and Learning” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11827284/ ) Preston and colleagues examined ‘spirituality of science: feelings of meaning, awe, and connection derived through scientific ideas.’ And found that it predicted meaning in life and emotional well-being even in atheists and agnostics.

 

Spirituality extends beyond religion.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Preston JL, Coleman TJ 3rd, Shin F. Spirituality of Science: Implications for Meaning, Well-Being, and Learning. Pers Soc Psychol Bull. 2025 Apr;51(4):632-643. doi: 10.1177/01461672231191356. Epub 2023 Aug 25. PMID: 37632126; PMCID: PMC11827284.

 

Abstract

Scientists often refer to spiritual experiences with science. This research addresses this unique component of science attitudes—spirituality of science: feelings of meaning, awe, and connection derived through scientific ideas. Three studies (N = 1,197) examined individual differences in Spirituality of Science (SoS) and its benefits for well-being, meaning, and learning. Spirituality of Science was related to belief in science, but unlike other science attitudes, spirituality of science was also associated with trait awe and general spirituality (Study 1). spirituality of science also predicted meaning in life and emotional well-being in a group of atheists and agnostics, showing that scientific sources of spirituality can provide similar psychological benefits as religious spirituality (Study 2). Finally, Spirituality of Science predicted stronger engagement and recall of scientific information (Study 3). Results provide support for an experience of spirituality related to science, with benefits for meaning, well-being, and learning.

 

Yoga is Associated with Lower Rates of Multimorbidity in Adults over 45

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Flexibility exercises, like yoga, can help maintain mobility as you age.

By John M. de Castro, Ph.D.

 

In today’s Research News article “Association between yoga and multimorbidity: a nationwide study of 279,885 middle-aged and older adults” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11884150/ ) Wang and colleagues examined practice of yoga and the likelihood of adults over 45 years of age having multiple diseases, including obesity, diabetes, hyperlipidemia, and hypertension. They found that the higher the duration and frequency of yoga practice the less the likelihood that the adult will have multiple diseases simultaneously.

 

Yoga practice is associated with lower risk of multimorbidity in older adults.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Wang K, Wang P, Li Y, Wang C, Veldheer S, Wang F, Na M, Sun L, Gao X. Association between yoga and multimorbidity: a nationwide study of 279,885 middle-aged and older adults. BMC Public Health. 2025 Mar 6;25(1):888. doi: 10.1186/s12889-025-22035-5. PMID: 40050815; PMCID: PMC11884150.

Abstract

Background

The health benefits of exercise have been well-established, but the specific role of yoga in multimorbidity was less understood. This study aimed to examine the association between yoga and multimorbidity in comparison with other exercises or non-exercise.

Methods

This cross-sectional study pooled nationally representative surveys from Behavioral Risk Factor Surveillance System (BRFSS) (2015, 2017, and 2019), and classified 279,885 participants aged 45 + years as yoga practitioners, other exercisers, and non-exercisers. Multinominal and binary logistic regressions were separately used for association of yoga with multimorbidity (coexistence of ≥ 2 conditions) and individual chronic conditions. Potential effect modification by age, sex, education level, and race/ethnicity was examined. We further assessed the dose-response association of duration and frequency of yoga practice with multimorbidity.

Results

The adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for yoga practitioners (n = 5081) vs. other exercisers (n = 192,718) were 0.69 (95% CI 0.55–0.86) for coexistence of two conditions, and 0.72 (95%CI 0.58–0.89) for coexistence of ≥ 3 conditions. The associations were stronger (ORs ranged from 0.43 to 0.52; P < 0.0001 for all) when comparing yoga practitioners with non-exercisers (n = 82,086), which were more pronounced in women relative to men (P-interaction < 0.05). Increased duration or frequency of yoga practice was associated with lower odds of multimorbidity in a dose-response manner (P for trend<0.0001 for all). Similar inverse associations were observed between yoga and individual chronic conditions.

Conclusion

Yoga was associated with lower odds of multimorbidity in middle-aged and older adults, relative to other exercises or non-exercise.

 

Mindfulness is Associated with Greater Subjective, and Psychological Well-Being

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What Is Subjective Well-Being? 8 Ways to Improve Yours

By John M. de Castro, Ph.D.

 

In today’s Research News article “Mindfulness, subjective, and psychological well-being: A comparative analysis of FFMQ and MAAS measures” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11914683/ )  Stuart-Edwards examined the relationships of mindfulness with subjective and psychological well-being. She found that mindfulness promoted subjective and psychological well-being by improving self‐efficacy, optimism, hope, and resiliency.

 

Improve well-being with mindfulness.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Stuart-Edwards A. Mindfulness, subjective, and psychological well-being: A comparative analysis of FFMQ and MAAS measures. Appl Psychol Health Well Being. 2025 May;17(2):e70019. doi: 10.1111/aphw.70019. PMID: 40098329; PMCID: PMC11914683.

 

Abstract

This study investigates the relationships of mindfulness with subjective well‐being and psychological well‐being through the mediating role of psychological capital. It also compares the Mindful Attention Awareness Scale (MAAS) and the Five Facet Mindfulness Questionnaire (FFMQ) in relation to these outcomes. Using a randomized controlled design, 185 participants from Prolific completed a brief two‐week mindfulness intervention, with one pre‐ and two post‐intervention measures. While the intervention effects were limited, the findings reveal that mindfulness is positively and similarly associated with both SWB and PWB, with stronger indirect links to PWB via PsyCap. While both measures of mindfulness had similar relationships with all outcomes, the multidimensional FFMQ offered additional insights, identifying the “describing” facet as particularly influential for both SWB and PWB, informing new potential paths for theorizing and practice.

Meditation Improves Attention

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How to Help Patients Improve Sustained Attention - HappyNeuron Pro - Blog

By John M. de Castro, Ph.D.

 

In today’s Research News article “The impact of meditation on sustained attention in nonclinical population: An extensive review” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11925505/ )  Roy and Subramanya review and summarize the published research on the impact of focused and open monitoring meditation on sustained attention. They report that the published research found that both meditation techniques significant improved sustained attention while focused meditation additionally significantly lowering perceived stress.

 

Improve attention with meditation.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Roy A, Subramanya P. The impact of meditation on sustained attention in nonclinical population: An extensive review. J Ayurveda Integr Med. 2025 Mar-Apr;16(2):101057. doi: 10.1016/j.jaim.2024.101057. Epub 2025 Mar 4. PMCID: PMC11925505.

 

Abstract

Background

Meditation, encompassing focussed attention (FA) and open monitoring (OM) approaches, is recognised for its potential to enhance cognitive functions. Sustained attention, a critical component of attentional processes, influences cognitive capacity and is linked to meditation benefits. However, a robust and extensive review analysis needs to address the specific relationship between meditation and sustained attention in nonclinical populations.

Methods

Following PRISMA guidelines, the authors reviewed English articles published from 2013 to 2023 in Q1 SCOPUS-indexed journals. Inclusion criteria comprised original research studies exploring the impact of meditation on sustained attention in healthy individuals. The modified Jadad Scale assessed methodological quality.

Results

12 studies (four RCTs, eight non-RCTs) with 1447 participants were included. Concentrative or FA meditation demonstrated consistent positive effects on sustained attention, including reduced perceived stress and increased focussed attention. OM meditation significantly improved sustained attention, as evidenced by reduced mind wandering and enhanced N2 responses. Meditators consistently outperformed non-meditators in sustained attention tasks, demonstrating faster reactions and lower error rates.

Discussion

This review explored the impact of meditation on sustained attention across diverse non-clinical populations through 12 investigations involving 1447 subjects with meditation interventions spanning from 21 days to 3 months. The study revealed that both FA and OM meditation approaches positively impact sustained attention, highlighting their potential role in enhancing cognitive function. Meditators consistently exhibited superior sustained attention abilities, suggesting the cognitive benefits of regular meditation practice. The findings of this study are consistent with prior research, contributing to the growing body of knowledge on the advantageous impacts of meditation on sustained attention. However, caution is needed in generalizing findings due to study limitations. Future research should use standardized methodologies and conduct longer-term follow-ups to better elucidate the effects of meditation interventions on sustained attention across diverse populations.

 

Mindfulness Reduces Binge Eating

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Let's Talk About Binge Eating Disorder (BED) - Behavioral Health Clinic | Counseling & Therapy Services

By John M. de Castro, Ph.D.

 

In today’s Research News article “Mindfulness-based interventions for binge eating: an updated systematic review and meta-analysis” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11893636/ ) Liu and colleagues review, summarize, and perform a meta-analysis on published research studies on the application of mindfulness therapies on binge eating. They report that the published research found that mindfulness therapies significantly reduced binge eating.

 

Use mindfulness therapies to treat binge eating.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu J, Tynan M, Mouangue A, Martin C, Manasse S, Godfrey K. Mindfulness-based interventions for binge eating: an updated systematic review and meta-analysis. J Behav Med. 2025 Feb;48(1):57-89. doi: 10.1007/s10865-025-00550-5. Epub 2025 Feb 20. PMID: 39979674; PMCID: PMC11893636.

 

Abstract

Mindfulness-based interventions (MBIs) have gained popularity in recent years in treating binge eating. Previous reviews and meta-analyses have found that MBIs demonstrated medium-large to large effects in reducing binge eating. However, as the literature on this topic has been growing rapidly, an updated review on MBIs’ effectiveness is much needed. This study is a 10-year update of the Godfrey, Gallo, & Afari (2015) systematic review and meta-analysis of MBIs for binge eating. PubMED, PsycINFO, and Web of Science were searched using keywords including binge eating, overeating, objective bulimic episodes, acceptance and commitment therapy, dialectical behavior therapy, mindfulness, meditation, and mindful eating. Results indicate there has been a large increase in the number of studies testing MBIs for binge eating in the past 10 years with 54 studies meeting inclusion criteria, compared to 19 ten years ago. The majority of the studies yielded large and medium effect sizes. The random effects meta-analysis of between-group effect sizes yielded medium-large effects for MBIs versus non-psychological intervention controls at post-treatment (mean Hedge’s g = − 0.65) and follow-up (mean Hedge’s g = − 0.71), and negligible effects for MBIs versus active psychological controls at post-treatment (mean Hedge’s g = − 0.05) and follow-up (mean Hedge’s g = 0.13). Of all MBIs, DBT had the most studies with large effects. More studies examined MBIs that directly targeted binge eating had larger effects than studies with MBIs targeting other health outcomes (with binge eating as a secondary outcome). New studies included in the current review were internationally-conducted, focused more on participants with overweight or obesity, involved more self-help and technology-based components, and had more novel and innovative interventions components. Future MBIs research should conduct more RCTs comparing MBIs with other psychological interventions, conduct meta-analyses to examine the effectiveness of different types of MBIs and intervention targets, and extend follow-up periods.

 

Relieve Acute Stress Responses to Traumatic Bone Fractures with Mindfulness

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Fracture Treatment for Most Common Types of Fractures - Propel Physiotherapy

By John M. de Castro, Ph.D.

 

In today’s Research News article “The Role of Mindfulness Decompression Therapy in Managing Acute Stress Disorder in Traumatic Fracture Patients” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11726210/ ) Chen and colleagues examined the effectiveness of Mindfulness-Based Stress Reduction (MBSR) therapy in alleviating the acute stress responses following traumatic bone fractures. These stress responses include traumatic experiences, persistent tension, irritability, and sleep disorders. They found that MBSR produced significant reductions in these acute stress response symptoms.

 

Treatment with Mindfulness-Based Stress Reduction (MBSR) alleviates the acute stress response as a result of traumatic bone fractures.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Chen X, Tian C, Zhang Y, Fu Y, Han W, Zhang R. The Role of Mindfulness Decompression Therapy in Managing Acute Stress Disorder in Traumatic Fracture Patients. Actas Esp Psiquiatr. 2025 Jan;53(1):71-79. doi: 10.62641/aep.v53i1.1668. PMID: 39801417; PMCID: PMC11726210.

Abstract

Background:

Traumatic fractures are common orthopedic injuries with higher incidence globally, leading to acute stress disorder (ASD). Therefore, this study aimed to analyze the clinical outcomes of mindfulness-based stress reduction (MBSR) therapy in patients with traumatic bone fractures suffering from ASD.

Methods:

This study included 135 patients who underwent trauma and fracture treatment at The 305th Hospital of the PLA between August 2021 and August 2023. Based on their participation in MBSR therapy, they were categorized into a conventional group (n = 62) and a combined group (n = 73). We comparatively analyzed the ASD Scale (ASDS), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Self-Rating Sleep Status Scale (SRSS), and World Health Organization Quality of Life (WHOQOL) measurement–BREF (WHOQOL–BREF) scores between these two experimental groups. Furthermore, we assessed the incidence of ASD after treatment between these two groups.

Results:

There were no significant differences in gender, age, body mass index, education, income, type of expense, trauma type, marital status, fracture site, diabetes status, hypertension status, and the pain visual analog scale (VAS) score, activities of daily living (i.e., modified Barthel index) score, and Social Support Rating Scale score between the two experimental groups (p > 0.05). Moreover, no significant differences were found in the prevalence of ASDS before treatment between these two groups (p > 0.05). However, after treatment, the ASDS score was significantly lower in the combined group than in the conventional group (p < 0.05). Furthermore, post-management analysis revealed that the incidence rate of ASD was 24.19% in the conventional group and 8.22% in the combined group. Moreover, the incidence of ASD was significantly lower in the combined group compared to the conventional group (p < 0.05). Before intervention, the difference in the SAS or SDS between patients was not statistically significant (p > 0.05). However, following treatment, the SAS and SDS scores of patients were significantly lower in the combined group than in the conventional group (p < 0.05). Similarly, after treatment, the SRSS scores of patients were substantially lower in the combined group than in the conventional group (p < 0.05). Furthermore, the WHOQOL–BREF score of patients was significantly greater in the combined group than in the conventional group (p < 0.05).

Conclusion:

MBSR therapy can significantly alleviate ASD in trauma and fracture patients. Furthermore, this approach can alleviate the incidence of ASD and reduce anxiety, depression, and negative emotions in patients. These positive effects collectively improve sleep quality and overall well-being of patients.

Change the Brain to Improve Personal Qualities with Loving Kindness Meditation

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Loving-Kindness Meditation – Teacher-Life-Coach

By John M. de Castro, Ph.D.

 

In today’s Research News article “Loving-Kindness Meditation: Systematic Review of Neuroimaging Correlates in Long-Term Practitioners and Clinical Implications.” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11870839/ ) Bashir and colleagues review and summarize the published research studies on changes in the brain resulting from long-term practice of Loving Kindness Meditation (LKM). They report that the brains of LKM practitioners have changes in the superior parietal lobe, inferior frontal gyrus, medial frontal lobe, and insular cortex. These areas are associated with self‐compassion, cognitive and affective empathy, and prosociality.

 

Long-term Loving Kindness Meditation changes brain structures responsible for the personal qualities produced by the practice.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Bashir K, Edstrom SB, Barlow SJ, Gainer D, Lewis JD. Loving-Kindness Meditation: Systematic Review of Neuroimaging Correlates in Long-Term Practitioners and Clinical Implications. Brain Behav. 2025 Mar;15(3):e70372. doi: 10.1002/brb3.70372. PMID: 40022190; PMCID: PMC11870839.

 

ABSTRACT

Introduction

Loving‐kindness meditation (LKM), a meditation type focused on nurturing love and compassion for oneself and others, has been shown to provide mental health benefits, and LKM interventions are being investigated for mental disorders. The benefits of long‐term practice, such as increased self‐compassion, greater cognitive and affective empathy, and prosocial behavior, are proposed to be due to neuroplastic changes that support well‐being. This systematic review aims to summarize the differences in brain structure and function in long‐term practitioners (LTPs) of LKM versus controls to identify possible underlying mechanisms that support mental health and drive treatment effect.

Methods

The literature search included Google Scholar, PubMed, and APA PsycINFO from inception through November 13, 2023.

Results

After review, five studies (64 LTPs and 67 controls total) were included. Brain regions with between‐group differences reported in at least two studies include the superior parietal lobe, inferior frontal gyrus, medial frontal lobe, and insular cortex.

Conclusion

These areas are responsible for self‐compassion, cognitive and affective empathy, and prosociality—personal qualities believed to be fostered through LKM practice. Longitudinal neuroimaging and neurophysiological studies incorporating LKM interventions for specific mental disorders are needed to further inform the biological basis of these treatments and may provide surrogate outcome measures for future clinical trials to refine this promising treatment modality.

 

Improve Mental Health with Mindfulness

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What Is Mindfulness-Based Cognitive Therapy (MBCT)?

By John M. de Castro, Ph.D.

 

In today’s Research News article “Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11900371/ ) Gkintoni and colleagues reviewed and summarized the published research studies of the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on mental health. They report that MBCT significantly reduced depression, anxiety, and stress and increased cognition and the regulation of emotions.

 

So, mindfulness-based therapy improves mental health.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Gkintoni E, Vassilopoulos SP, Nikolaou G. Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being. J Clin Med. 2025 Mar 3;14(5):1703. doi: 10.3390/jcm14051703. PMCID: PMC11900371.

Abstract

Background/Objectives: This systematic review outlines the neurocognitive outcomes and mechanisms of mindfulness-based cognitive therapy (MBCT) that influence subjective well-being. MBCT is a clinical intervention that integrates cognitive therapy with mindfulness practices to prevent depression relapses and improve mental health. Methods: The review focuses on the effects of MBCT on brain structure changes, cognitive processes, and emotional regulation, which are related to improvements in subjective well-being. A total of 87 studies were included in the review to assess the effectiveness of MBCT. Results: Evidence from the studies highlights the effectiveness of MBCT in reducing symptoms of depression, anxiety, and stress. MBCT was also shown to enhance cognitive functions and emotional regulation across diverse populations. These findings point to the potential for MBCT to induce neuroplastic changes in the brain and widen the applicability of the treatment for a variety of disorders, calling for further research into long-term benefits and underlying neurobiological mechanisms. Conclusions: The review emphasizes the potential of MBCT to bring about neuroplastic changes, calling for further research into its long-term benefits and the underlying neurobiological mechanisms. This study underlines the need to incorporate multidisciplinary measures by integrating psychology and neuroscience to comprehend comprehensively the effects of MBCT.