Anxiety

Perfectionism is Lower in Mindful People Because of Lower Perfectionism and Anxiety

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Fig 2

By John M. de Castro, Ph.D.

 

In today’s Research News article “Maladaptive perfectionism can explain the inverse relationship between dispositional mindfulness and procrastination” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11819553/ ) Ibili and colleagues investigated the relationship between mindfulness and lower levels of procrastination. They report that mindfulness is associated with lower levels of procrastination as a result of being associated with lower levels of perfectionism and anxiety and these, in turn, are associated with lower levels of procrastination. Hence, procrastination is lower in mindful individuals because perfectionism and anxiety are lower on mindful individuals.

 

Being mindful is associated with lower anxiety and perfectionism that are associated with less procrastination.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Ibili G, Tree JJ, Gurluk YO. Maladaptive perfectionism can explain the inverse relationship between dispositional mindfulness and procrastination [published correction appears in PLoS One. 2025 Apr 4;20(4):e0322030. doi: 10.1371/journal.pone.0322030.]. PLoS One. 2025;20(2):e0318845. Published 2025 Feb 12. doi:10.1371/journal.pone.0318845

 

Abstract

Given the widespread occurrence of procrastination and its adverse association with well-being, investigating the individual variables that influence procrastination is a crucial matter. Previous research has identified dispositional mindfulness to be negatively associated with procrastination, but the underlying mechanisms driving this relationship remain unclear. In this study, the aim was to investigate whether the inverse relationship between dispositional mindfulness and procrastination could be explained by the mediating roles of trait anxiety and maladaptive perfectionism. In a cross-sectional survey, 126 participants (aged 18–33) completed the 15-Item Five-Facet Mindfulness Questionnaire, the State-Trait Anxiety Inventory-Trait Form, the Almost Perfect Scale-Revised, and the Pure Procrastination Scale. A parallel mediation model was tested to investigate the mediating role of self-reported maladaptive perfectionism and trait anxiety to explain the relationship between dispositional mindfulness and procrastination with a bootstrapped multivariate technique. The results revealed that maladaptive perfectionism significantly mediated the relationship between mindfulness and procrastination -indicating that dispositional mindfulness has a significant indirect effect on procrastination via decreased levels of maladaptive perfectionism. It was determined that 15% of the variance in procrastination was significantly explained by this model (R2 = .15, β =  −.39, B =  −.83, 95% CI =  [−1.18, −.48], p < .001]. As the study highlights the importance of maladaptive perfectionism to explain the link between mindfulness and procrastination, we suggest that future research could investigate the influence of mindfulness on procrastination via mindfulness-based interventions, and include measurements of both trait anxiety and maladaptive perfectionism across longitudinal or experimental designs to unpack causality with respect to our pattern of observed findings.

 

Improve Psychological Well-Being in Patients with Diabetes or Hypertension with Tai Chi and Qigong

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By John M. de Castro, Ph.D.

 

In today’s Research News article “Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12002851/ ) Santos and colleagues examined the psychological impact of Tai Chi and Qigong practice on patients with diabetes and/or hypertension. They found that the practices significantly reduced anxiety and stress in the patients.

 

Tai Chi and Qigong practice reduces anxiety and stress in patients with diabetes and/or hypertension.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Santos LRAC, Taíra A, Possobon RDF, et al. Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial. Einstein (Sao Paulo). 2025;23:eAO1076. Published 2025 Mar 17. doi:10.31744/einstein_journal/2025AO1076

 

In Brief

A 13-week Tai Chi/Qigong intervention reduced anxiety and stress in middle-aged and older Brazilian patients with diabetes and hypertension. With significant improvements in the State-Trait Anxiety Inventory and PSS14 scores, this practice shows potential as an effective adjunctive therapy in primary care.

ABSTRACT

Objective:

This study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and diabetic individuals assisted in a primary healthcare setting.

Methods:

Ninety-one patients with diabetes mellitus and/or hypertension diagnosed and followed up at a primary care center were randomized to the Tai Chi/Qigong intervention (n = 45) or waitlist (n = 46) group for 13 weeks. Outcome measures were collected at baseline and at 6 and 13 weeks for anxiety (State-Trait Anxiety Inventory [STAI]) and stress (Perceived Stress Scale – PSS14). The primary endpoint of the study was 13 weeks. We used a linear mixed-effects model to analyze the primary and secondary outcomes, considering the treatment group and time as covariates and treating the subject as a random effect.

Results:

Of the included 91 participants, 53 completed the 6-week assessment, and 42 completed the 13-week assessment. After 13 weeks, the Tai Chi/Qigong Group had lower scores for anxiety (STAI Estimate = -6.421; SD = 2.679; 95% confidence interval (95%CI) = [-11.615,-1.224]; p = 0.018) and stress (PSS14 Estimate = -9.290; SD= 2.262; 95%CI= [-13.678,-4.906]; p<0.001).

Conclusion:

A 13-week Tai Chi/Qigong intervention was efficacious in lowering anxiety and perceived stress scores in middle-aged and older patients with diabetes mellitus and hypertension and can potentially be used in primary care centers as an adjunct therapy.

 

Postpartum Depression is Improved With Virtual Reality Mindfulness and Yoga Training

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Fig. 1

By John M. de Castro, Ph.D.

 

In today’s Research News article “Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11973155/  ) Liu and colleagues examined the effectiveness of virtual reality (VR) enhanced mindfulness meditation and yoga training in comparison to traditional training and a no-training control on the symptoms of postpartum depression. They report that the VR enhanced training produced greater decreases in depression, anxiety, and stress and increases in cognitive control than the traditional training or no-treatment controls.

 

Improve postpartum depression symptoms with virtual reality mindfulness and yoga training.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu N, Deng J, Lu F, Xiao J. Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era. Sci Rep. 2025;15(1):11766. Published 2025 Apr 6. doi:10.1038/s41598-025-96165-6

Abstract

The postpartum period has witnessed increasing rates of depression and anxiety, particularly in the context of the COVID-19 pandemic, with these conditions often co-occurring and being exacerbated by the lingering effects of long COVID. Traditional interventions, such as mindfulness-based stress reduction (MBSR) and yoga, have demonstrated effectiveness in alleviating these symptoms. However, the limitations of in-person sessions, especially in the context of pandemic-related restrictions, highlight the need for accessible, innovative approaches. Integrating Virtual Reality (VR) technology with these traditional practices presents a novel solution, offering immersive, customizable environments that may enhance engagement and therapeutic outcomes. This study evaluates the effectiveness of a VR-enhanced mindfulness and yoga intervention in treating postpartum depression and anxiety in women affected by long COVID, with additional examination of underlying physiological stress markers and cognitive control mechanisms. In this randomized controlled trial, 111 postpartum women were randomly assigned to experimental (VR-enhanced intervention), control (traditional in-person sessions), or blank groups using computer-generated randomization. The 8-week intervention involved thrice-weekly 60-minute sessions. Outcomes were assessed at baseline, post-intervention, and 4-week follow-up using the Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder-7 (GAD-7) scale, salivary cortisol measurements, and an emotional Stroop task. The VR-enhanced intervention group demonstrated significant improvements in both depression (EPDS: P < 0.001, ηp2 = 0.18) and anxiety symptoms (GAD-7: P < 0.001, ηp2 = 0.17), with these therapeutic effects significantly greater than those observed in the control and blank groups (P < 0.001 for both comparisons). These improvements were strongly correlated (r = 0.68, P < 0.001). Supporting these primary outcomes, salivary cortisol levels showed a significant decrease (P < 0.001, ηp2 = 0.13), and cognitive control improved as evidenced by reduced emotional Stroop task conflict effect (P < 0.001, ηp2 = 0.37). Correlation analysis revealed robust associations between improvements in depression and anxiety symptoms and changes in physiological markers in both short-term and long-term outcomes. This study demonstrates that integrating VR technology with traditional mindfulness and yoga practices effectively reduces both postpartum depression and anxiety symptoms in the post-COVID era. The parallel improvements in physiological stress markers and cognitive control provide insight into potential mechanisms underlying these therapeutic effects. These findings underscore the value of immersive technology in enhancing traditional therapeutic approaches for addressing postpartum depression and anxiety in the post-pandemic context.

 

Yoga Meditation Improves Mental Health in Female College Students

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Why should college students go for Yoga & Meditation? - Blog | Graphic Era

By John M. de Castro, Ph.D.

 

In today’s Research News article “From contemplation to serenity: how yoga meditation improves the mental health of female college students” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11931514/ ) Liu and colleagues studied the effects of yoga meditation on the mental health of female college students. They report that yoga meditation improved the women’s mental health including significantly reduced anxiety, depression, and stress and increased emotional regulation and self-awareness.

 

Improve mental health with yoga meditation.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu L, Liu C, Tang L, Wang X, Feng Q. From contemplation to serenity: how yoga meditation improves the mental health of female college students?. Front Psychol. 2025;16:1545943. Published 2025 Mar 10. doi:10.3389/fpsyg.2025.1545943

Abstract

Objective

This study aims to investigate the impact of yoga meditation on the mental health of female college students, focusing on how meditation improves emotional regulation, alleviates stress and strengthens psychological resilience.

Methods

Employing a combination of quantitative assessment and qualitative analysis, the study measured participants’ emotional states, stress levels, and psychological resilience across multiple time points to track participants’ mental health changes dynamically. In-depth interviews and analysis of meditation journals were also conducted.

Results

Yoga meditation significantly reduced anxiety, depression, and perceived stress while enhancing emotional regulation and self-awareness. Meditation positively influenced neuroplasticity, inducing beneficial changes in brain regions associated with emotional control and cognitive flexibility. Additionally, improved autonomic nervous system function was observed, with increased parasympathetic activity and reduced sympathetic response. Meditation strengthened psychological resilience in female college students, improved stress-coping strategies, and sustained positive mental health benefits even after the intervention.

Conclusion

Yoga meditation is an effective mental health intervention, bolstering emotional regulation and reducing stress among female college students. Integrating yoga meditation into campus mental health programs is recommended to provide students with greater practice opportunities and personalized guidance.

Parkinson’s Disease Symptoms are Improved by Meditation or Yoga

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Parkinson's Disease | Contemplative Studies

By John M. de Castro, Ph.D.

 

In today’s Research News article “Effects of Meditation and Yoga on Anxiety, Depression and Chronic Inflammation in Patients with Parkinson’s Disease: A Randomized Clinical Trial” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11965853/ ) Kwok and colleagues studied the effects of meditation and yoga practice on the symptoms of Parkinson’s Disease. They found that these practices significantly relieved a wide variety of symptoms, including anxiety, depression, inflammation, movement problems, and improved quality of life.

 

Meditation and yoga relieve the symptoms of Parkinson’s disease.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Jojo Yan Yan Kwok, Lily Man Lee Chan, Charis Ann Lai, Philip Wing Lok Ho, Zoe Yuen-kiu Choi, Man Auyeung, Shirley Yin Yu Pang, Edmond Pui Hang Choi, Daniel Yee Tak Fong, Doris Sau Fung Yu, Chia-chin Lin, Richard Walker, Samuel Yeung Shan Wong, Rainbow Tin Hung Ho. Effects of Meditation and Yoga on Anxiety, Depression and Chronic Inflammation in Patients with Parkinson’s Disease: A Randomized Clinical Trial. Psychother Psychosom. 2025 Feb 28;94(2):101–118.

Abstract

Introduction

Clinical guidelines recommend a holistic approach to Parkinson’s disease (PD) care, yet randomized trials examining mindfulness-based interventions in this context are scarce. This study investigated the effects of two mindfulness practices – meditation and yoga – on biopsychosocial outcomes in PD patients, including anxiety symptoms, depressive symptoms, motor/nonmotor symptoms, health-related quality-of-life (HRQOL), mindfulness, and stress and inflammation biomarkers, compared to usual care.

Methods

159 participants with a clinical diagnosis of idiopathic PD and a Hoehn and Yahr stage of 1, 2, and 3, were randomized into meditation (n = 53), yoga (n = 52), and control (n = 54). Meditation and yoga were delivered in 90-min groups for 8 weeks. Primary outcomes included anxiety symptoms and depressive symptoms. Secondary outcomes included motor and nonmotor symptoms, HRQOL, mindfulness, and serum levels of interleukin-6, cortisol and TNF-alpha. Assessments were done at baseline (T0), 2 months (T1), and 6 months (T2). Linear mixed models were conducted following intention-to-treat principle.

Results

Compared to control, both meditation, and yoga groups had significant improvements in anxiety symptoms (meditation: mean difference [MD] = −1.36, 95% CI: −2.46 to−0.26; yoga: MD = −1.61, CI: −2.70 to −0.52), motor symptoms (meditation: MD = −5.35, CI: −8.61 to−2.09; yoga: MD = −6.59, CI: −9.82 to−3.36), HRQOL (meditation: MD = −2.01, CI: −3.41 to−0.62; yoga: MD = −1.45, CI: −2.83 to−0.08), and describing skills (meditation: MD = 0.97, CI: 0.04–1.89; yoga: MD = 0.92, CI: 0.01–1.84) at T1, and significant reductions in serum interleukin-6 levels (meditation: MD = −1.14, CI: −2.18 to−0.10; yoga: MD = −1.11, CI: −2.09 to−0.13) at T2. Only meditation significantly reduced depression (MD = −1.44, CI: −2.57 to−0.30) at T1 and sustained the motor and HRQOL improvements at T2.

Conclusion

Meditation and yoga significantly improved anxiety symptoms, chronic inflammation, motor symptoms, mindfulness-describing facet, and HRQOL in PD patients. Meditation provided additional benefits in reducing depressive symptoms and sustaining motor and HRQOL improvements.

 

Improve Mental Health with Mindfulness

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What Is Mindfulness-Based Cognitive Therapy (MBCT)?

By John M. de Castro, Ph.D.

 

In today’s Research News article “Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11900371/ ) Gkintoni and colleagues reviewed and summarized the published research studies of the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on mental health. They report that MBCT significantly reduced depression, anxiety, and stress and increased cognition and the regulation of emotions.

 

So, mindfulness-based therapy improves mental health.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Gkintoni E, Vassilopoulos SP, Nikolaou G. Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being. J Clin Med. 2025 Mar 3;14(5):1703. doi: 10.3390/jcm14051703. PMCID: PMC11900371.

Abstract

Background/Objectives: This systematic review outlines the neurocognitive outcomes and mechanisms of mindfulness-based cognitive therapy (MBCT) that influence subjective well-being. MBCT is a clinical intervention that integrates cognitive therapy with mindfulness practices to prevent depression relapses and improve mental health. Methods: The review focuses on the effects of MBCT on brain structure changes, cognitive processes, and emotional regulation, which are related to improvements in subjective well-being. A total of 87 studies were included in the review to assess the effectiveness of MBCT. Results: Evidence from the studies highlights the effectiveness of MBCT in reducing symptoms of depression, anxiety, and stress. MBCT was also shown to enhance cognitive functions and emotional regulation across diverse populations. These findings point to the potential for MBCT to induce neuroplastic changes in the brain and widen the applicability of the treatment for a variety of disorders, calling for further research into long-term benefits and underlying neurobiological mechanisms. Conclusions: The review emphasizes the potential of MBCT to bring about neuroplastic changes, calling for further research into its long-term benefits and the underlying neurobiological mechanisms. This study underlines the need to incorporate multidisciplinary measures by integrating psychology and neuroscience to comprehend comprehensively the effects of MBCT.

 

Online Yoga Improves the Psychological Health of Cancer Patients

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The pros and cons of online yoga - Ekhart Yoga

By John M. de Castro, Ph.D.

 

In today’s Research News article “The Effects of Online Yoga Practice on Cancer Patients: A Systematic Review” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11817149/ ) Gatti and colleagues reviewed and summarized the published research studies on the effectiveness of yoga practice presented online to alleviate the psychological sequala of a cancer diagnosis. They report that online yoga significantly increases sleep quality and quality of life and reduces stress, anxiety, depression, and fatigue in patients with a diagnosis of cancer.

 

Yoga practice improves the psychological health of cancer patients.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Gatti F, Perego G, Milano F, Calleri G, Giurioli B, Di Mattei VE. The Effects of Online Yoga Practice on Cancer Patients: A Systematic Review. Healthcare (Basel). 2025 Jan 23;13(3):225. doi: 10.3390/healthcare13030225. PMID: 39942415; PMCID: PMC11817149.

 

Abstract

Background: Cancer remains a leading cause of death, with 9.7 million deaths in 2022. Despite advancements in diagnosis and treatment, many cancer patients experience side effects that significantly impact their quality of life, including chronic pain, anxiety, depression, sleep disturbances, and cancer-related fatigue. Non-pharmacological interventions, such as yoga, have gained attention for their potential to reduce stress and improve overall well-being. However, barriers such as fatigue, pain, and transportation issues limit access to in-person yoga, leading to the growing adoption of online yoga as a viable alternative. Objective: This systematic review synthesizes research on the effectiveness of online yoga for cancer patients. A comprehensive search was conducted across Medline, PsycINFO, and Scopus databases on 24 October 2024. The methodological quality of the studies was assessed using the CASP Checklist. Of 6266 articles initially identified, 14 studies met the inclusion criteria, comprising qualitative (n = 4) and quantitative (n = 10) studies. Results: The results suggest that online yoga can improve stress and sleep quality, with moderate effects on anxiety, depression, and fatigue. However, variability in study designs and methodological limitations complicate the evaluation of its overall effectiveness. Conclusions: Online yoga offers a practical, accessible option for cancer patients unable to attend in-person sessions, showing the potential to enhance mental and physical health outcomes. Nevertheless, the variability in study methodologies highlights the need for more standardized research to establish its role as a supportive intervention in oncology care.

 

Mindfulness Training Promotes Perinatal Mental Health

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How New Moms Can Have a Positive, Mindful Postpartum JourneyBy John M. de Castro, Ph.D.

 

In today’s Research News article “Development and Evaluation of a Mindfulness-Based Mobile Intervention for Perinatal Mental Health: Randomized Controlled Trial” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11786135/ ) Park and colleagues performed a randomized clinical trial comparing the effectiveness of a 4-week smartphone-based mindfulness program to a wait-list control condition on the mental health of pregnant women. They found that mindfulness training produced significant reductions in anxiety and increases in emotional well-being, mindfulness, and maternal-fetal attachment.

 

So, mindfulness training improves the mental health of pregnant women.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Park S, Cho HY, Park JY, Chung K, Jhung K. Development and Evaluation of a Mindfulness-Based Mobile Intervention for Perinatal Mental Health: Randomized Controlled Trial. J Med Internet Res. 2025 Jan 17;27:e56601. doi: 10.2196/56601. PMID: 39823585; PMCID: PMC11786135.

 

Abstract

Background

Perinatal mental health problems, such as anxiety, stress, and depression, warrant particularly close monitoring and intervention, but they are often unaddressed in both obstetric and psychiatric clinics, with limited accessibility and treatment resources. Mobile health interventions may provide an effective and more accessible solution for addressing perinatal mental health. Development and evaluation of a mobile mental health intervention specifically for pregnant women are warranted.

Objective

This study aimed to evaluate the effectiveness of a 4-week, self-administered mobile mindfulness intervention in reducing anxiety, depression, and stress, and improving emotional well-being, maternal-fetal attachment, and mindfulness skills in a general population of pregnant women.

Methods

Pregnant women were recruited and randomized to an intervention or a wait-list control group. The intervention group participated in a self-administered 4-week smartphone-based mindfulness program. Anxiety, depression, and stress were assessed as primary outcomes at baseline and postintervention. Secondary outcomes were mental health well-being, maternal-fetal attachment, and skills of mindfulness. The usability of the mobile intervention was also evaluated.

Results

A total of 133 pregnant women were randomly assigned to the intervention (n=66) or the control group (n=67). The overall dropout rate was 30% (39/133). Anxiety scores of the intervention group significantly decreased from baseline to postintervention (P=.03, Wilcoxon Signed-Rank test), whereas no significant changes were observed in the control group. Depression and stress scores showed no significant changes. Emotional well-being significantly improved in the intervention group (P=.01). Improvements were observed in maternal-fetal attachment, particularly in attributing characteristics to the fetus (P=.003) and in differentiating the self from the fetus (P=.006). Mindfulness awareness also showed significant improvement (P=.008). Significant between-group effects were identified for mindfulness awareness (P=.006) and attributing characteristics to the fetus (P=.002). After applying the false discovery rate corrections, within-group improvements in emotional well-being, maternal-fetal attachment, and mindfulness awareness remained significant, while between-group differences for emotional well-being and differentiation were not significant.

Conclusions

A mobile mindfulness program effectively reduced anxiety and improved emotional well-being, maternal-fetal attachment, and mindfulness awareness in the general population of pregnant women. Mobile interventions may offer a cost-effective and feasible method for promoting perinatal mental health.

 

Mindfulness Reduces Stress in Heart Disease Patients

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By John M. de Castro, Ph.D.

 

In today’s Research News article “Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction: Results of a Multicenter Randomized Controlled Trial” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11786073/ ) Spruill and colleagues examined the effectiveness of mindfulness training (Mindfulness Based Cognitive Therapy – MBCT) on stress levels of women diagnosed with myocardial infarction. They found that in comparison to an active control condition (heart disease education) the women who received mindfulness training had significantly lower perceived stress levels and the more they practiced the greater the reductions in stress, anxiety, and depression.

 

Hence, mindfulness improves the mental health of women with heart disease.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Spruill TM, Park C, Kalinowski J, Arabadjian ME, Xia Y, Shallcross AJ, Visvanathan P, Smilowitz NR, Hausvater A, Bangalore S, Zhong H, Park K, Mehta PK, Thomas DK, Trost J, Bainey KR, Heydari B, Wei J, Dickson VV, Ogedegbe G, Berger JS, Hochman JS, Reynolds HR. Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction: Results of a Multicenter Randomized Controlled Trial. JACC Adv. 2025 Jan 16;4(2):101530. doi: 10.1016/j.jacadv.2024.101530. PMID: 39898341; PMCID: PMC11786073.

 

Abstract

Background

Elevated perceived stress is associated with adverse outcomes following myocardial infarction (MI) and may account for poorer recovery among women vs men.

Objectives

This randomized controlled trial tested effects of a mindfulness-based intervention on stress levels among women with MI.

Methods

Women with elevated stress (Perceived Stress Scale [PSS-4]≥6) at least 2 months after MI were enrolled from 12 hospitals in the United States and Canada and via community advertising. Participants were randomized to a remotely delivered mindfulness intervention (MBCT-Brief) or heart disease education, both 8 weeks long. Follow-up was 6 months. Changes in stress (PSS-10; primary outcome) and secondary outcomes (depressive symptoms, anxiety, quality of life, disease-specific health status, actigraphy-assessed sleep) were compared between groups.

Results

The sample included 130 women with MI (mean age 59.8 ± 12.8 years, 34% racial/ethnic minorities). In intention-to-treat analysis, PSS-10 scores declined in the MBCT-Brief arm (−0.52 [95% CI: −0.77 to −0.28]) but not the heart disease education arm (−0.19 [95% CI: −0.45 to 0.06]; group×time interaction P = 0.070). The effect was stronger in per-protocol analysis of participants who completed ≥4 intervention sessions (P = 0.049). There were no significant differences in secondary outcomes in intention-to-treat or per-protocol analyses. Within the MBCT-Brief arm, more frequent mindfulness practice was associated with greater reductions in stress (P = 0.007), depressive symptoms (P = 0.017), and anxiety (P = 0.036).

Conclusions

MBCT-Brief was associated with greater 6-month reductions in stress than an active control among adherent participants. More frequent mindfulness practice was associated with greater improvements in psychological outcomes. Strategies to engage women with MI in mindfulness training and support regular home practice may enhance these effects.

 

Improve the Cognitive, Social, and Psychological States of Mild Alzheimer’s Patients with Mindfulness

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Improve the Cognitive, Social, and Psychological States of Mild Alzheimer’s Patients with Mindfulness

 

By John M. de Castro, Ph.D.

 

“You have to be patient with Alzheimer’s. Once you understand that it’s a medical condition, you become a little more compassionate. You get less frustrated.” – Kim Campbell

 

The normal aging process involves a systematic progressive decline in every system in the body, the brain included. The elderly often have problems with attention, thinking, and memory, known as mild cognitive impairment. But sometimes the decline is rapid and results in dementia; a progressive loss of mental function produced by degenerative diseases of the brain. It is quite common with about 3% of adults ages 70 to 74, 22% of adults ages 85 to 89 and 33% of adults ages 90 and older. Between 60% to 80% of dementia cases are classified as Alzheimer’s Disease.

 

An encouraging new development is that mindfulness practices such as meditation training and mindful movement practices can significantly reduce these declines in cognitive ability. In addition, it has been found that mindfulness practices reduce the deterioration of the brain that occurs with aging restraining the loss of neural tissue. This suggests that mindfulness may help to relieve some of the symptoms and/or slow the progression of mild Alzheimer’s Disease.

 

In today’s Research News article “Effects of Mindfulness-Based Interventions (MBIs) in Patients with Early-Stage Alzheimer’s Disease: A Pilot Study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046197/ )  Giulietti and colleagues recruited elderly (>70 years old) patients suffering from mild Alzheimer’s disease. They were randomly assigned to either receive no treatment or a once a week for 6-month mindfulness-based intervention including stress management, relaxation, and 15-minute meditations once in treatment and twice at home per week. At baseline and after 6-months the patients were measured with the Mini Mental States Inventory, and for health-related quality of life, depression, spiritual well-being, social status, everyday cognition, and neuropsychiatric symptoms.

 

In comparison to baseline the patients that received the mindfulness-based intervention had significantly greater levels of everyday cognition, spiritual well-being, and social functioning, and lower levels of depression, agitation/aggression, anxiety, apathy, euphoria, sleep, apathy, and appetite. Whereas the control patients had significantly worsening Mini Mental States Inventory, apathy, appetite, and depression.

 

Caution should be exercised in interpreting these results as it was a relatively small pilot study without an active control condition.

 

But the results suggest that mindfulness training improved the cognitive, social, and psychological states of mild Alzheimer’s disease patients while the untreated patients showed a worsening of their cognitive and psychological states.

 

 “People do not realize that Alzheimer’s is not old age. It is a progressive and fatal disease and staggering amounts of people develop Alzheimer’s every day.” – Melina Kanakaredes

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Giulietti MV, Spatuzzi R, Fabbietti P, Vespa A. Effects of Mindfulness-Based Interventions (MBIs) in Patients with Early-Stage Alzheimer’s Disease: A Pilot Study. Brain Sci. 2023 Mar 13;13(3):484. doi: 10.3390/brainsci13030484. PMID: 36979294; PMCID: PMC10046197.

 

Abstract

Bachground In this study, we hypothesize that mindfulness-based interventions (MBIs) may improve well-being and the related outcomes in Alzheimer’s dementia patients (AD-P) at an early stage. MBIs consist of the practice of consciously observing the psychic contents in the present moment (thoughts, sensations, feelings, and other events). This attention allows one to become aware of the psychic contents and integrate them, thus favoring the quality of life and an increase in the mood of practitioners. Methods The randomized controlled study enrolled 22 AD-P at an early stage (age ≥ 60 years) treated with MBIs and 22 patients without treatment (six months of MBI training). Tests (T0–T1 six months): Mini-Mental State Examination (MMPI); Spiritual Well-Being (SWB); Beck Depression Inventory (BDI); SF36. Test-Caregiver: Everyday Cognition scales (ECOG). Results AD-P with mindfulness: Improvement of ECOG (p = 0.026), quality of life (p < 0.001), spiritual well-being (p < 0.001); decrease in depression BDI (p < 0.001). The MMSE remains unchanged. The control group of untreated patients showed a significant worsening in all these dimensions. Conclusions MBI training is effective in increasing quality of life and preventing worsening in patients with early-stage Alzheimer’s dementia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046197/