Yoga Practice Improves Mental Health in Patients with Type 2 Diabetes

24. Benefits Of Yoga For Type 2 Diabetes

By John M. de Castro, Ph.D.

 

In today’s Research News article “The Impact of Yoga Intervention on Physical and Mental Health of Adults with Type 2 Diabetes” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12068464/ )  Subramani and colleagues examined the effectiveness of yoga practice on the mental health of patients with Type 2 Diabetes. They found that yoga practice produced significant reductions in depression and stress and increases in cognitive function and mindfulness.

 

Yoga improves mental health in patients with Type 2 Diabetes.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Subramani P, Mohan AR, Satish L, Karthikeyan S, Ravi P, Ulagamathesan V, Kannikan V, Viswanathan M. The Impact of Yoga Intervention on Physical and Mental Health of Adults with Type 2 Diabetes. Int J Yoga. 2025 Jan-Apr;18(1):67-73. doi: 10.4103/ijoy.ijoy_219_24. Epub 2025 Apr 22. PMID: 40365367; PMCID: PMC12068464.

 

Abstract

Aim:

To assess the impact of a yoga intervention on the physical and mental health of adults with type 2 diabetes.

Methods:

This study was conducted at Madras Diabetes Research Foundation, Chennai, for 6 months. Participants aged 18–65 years, diagnosed with type 2 diabetes mellitus (T2DM), and glycated hemoglobin (HbA1c) levels ranging from ≥7.0% to ≤10.5% were recruited. One hundred and fifty-two participants were randomized in 1:1 ratio to either the intervention or control arm by simple random method. The intervention included structured yoga practice for 35 min, every 2 weeks for a period of 12 weeks, and followed up for 3 months. Participants in the control arm received the standard care for diabetes. Sociodemographic data, anthropometric measurements, and blood samples were collected at baseline and final visit. Standard questionnaires were administered for assessing mental health parameters.

Results:

53 of 76 (70%) participants from the intervention arm and 70 of 76 (92%) participants from the control arm completed the study. The mean age of the participants was 53 ± 7.5 years. The mean duration of diabetes of the participants was 10 ± 6.9 years. HbA1c showed reduction postintervention, but this was not statistically significant compared to control. The intervention group showed statistically significant improvements in depression, stress, cognitive function, and mindfulness compared to the control arm.

Conclusion:

Yoga is helpful in reducing depression and stress and enhancing mindfulness and cognitive function in patients with T2DM.

Decrease Stress, Anxiety, Burnout, and Depression with Yoga Practice

Zen lounges, yoga helping HCA Houston nurses relieve stress

By John M. de Castro, Ph.D.

 

In today’s Research News article “A Systematic Review of Yoga Interventions on the Mental Health of Nursing Professionals and Students” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12068460/ ) Arya and colleagues reviewed and summarized the published research studies on the effects of yoga on nursing professionals and students. They report that the research found that yoga practice significantly reduced stress, anxiety, burnout, and depression and increased mindfulness and sleep quality in the nurses.

 

Yoga reduces stress, anxiety, burnout, and depression in nurses and nursing students.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Arya RG, Srivastava D, Divya BR, Madhu, Bhargav H. A Systematic Review of Yoga Interventions on the Mental Health of Nursing Professionals and Students. Int J Yoga. 2025 Jan-Apr;18(1):13-26. doi: 10.4103/ijoy.ijoy_195_24. Epub 2025 Apr 22. PMID: 40365361; PMCID: PMC12068460.

 

Abstract

This systematic review aimed to evaluate the impact of yoga interventions on preventing and alleviating mental health issues, including stress, anxiety, burnout, depression, and other related factors among nursing professionals and students. The review adhered to the PRISMA guidelines and was registered in PROSPERO (CRD42024512366). A comprehensive literature search was conducted in Google Scholar and PubMed using keywords such as “nursing students,” “nursing professionals,” “yoga interventions,” and “mental health.” Eligible studies were randomized controlled trials (RCTs) published from 1st January 2014 to 31st December 2024, involving nursing population and yoga-based interventions targeting mental health outcomes. The risk of bias was assessed using the CASP tool. The search identified 14 RCTs (967 participants, predominantly female, age range – 18 to 69 years) that met the eligibility criteria. The yoga intervention varied in duration (10 minutes to 1 hour per session), frequency (once to five times weekly), and protocols (Laughter yoga being the most common). Mental health outcomes such as stress, anxiety, burnout, mindfulness, depression, quality of sleep, and life satisfaction were assessed. Most studies reported significant improvements in these outcomes in the yoga

Improve Mental Health and Well-Being with Yoga Practice

Zen lounges, yoga helping HCA Houston nurses relieve stress

By John M. de Castro, Ph.D.

 

In today’s Research News article “A Systematic Review of Yoga Interventions on the Mental Health of Nursing Professionals and Students” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12068460/ ) Arya and colleagues reviewed and summarized the published research studies on the effectiveness of yoga interventions on the mental health of nurses and nursing students. They report that the published studies found that yoga interventions significantly improved mental health including reductions in stress, depression, and burnout and significant increases in sleep quality, mindfulness, and life satisfaction.

 

Yoga is effective in improving mental health and well-being among nurses and students.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Arya RG, Srivastava D, Divya BR, Madhu, Bhargav H. A Systematic Review of Yoga Interventions on the Mental Health of Nursing Professionals and Students. Int J Yoga. 2025;18(1):13-26. doi:10.4103/ijoy.ijoy_195_24

 

Abstract

This systematic review aimed to evaluate the impact of yoga interventions on preventing and alleviating mental health issues, including stress, anxiety, burnout, depression, and other related factors among nursing professionals and students. The review adhered to the PRISMA guidelines and was registered in PROSPERO (CRD42024512366). A comprehensive literature search was conducted in Google Scholar and PubMed using keywords such as “nursing students,” “nursing professionals,” “yoga interventions,” and “mental health.” Eligible studies were randomized controlled trials (RCTs) published from 1st January 2014 to 31st December 2024, involving nursing population and yoga-based interventions targeting mental health outcomes. The risk of bias was assessed using the CASP tool. The search identified 14 RCTs (967 participants, predominantly female, age range – 18 to 69 years) that met the eligibility criteria. The yoga intervention varied in duration (10 minutes to 1 hour per session), frequency (once to five times weekly), and protocols (Laughter yoga being the most common). Mental health outcomes such as stress, anxiety, burnout, mindfulness, depression, quality of sleep, and life satisfaction were assessed. Most studies reported significant improvements in these outcomes in the yoga intervention groups compared to control groups. Nine studies showed a significant stress reduction, and 3 studies found a decrease in anxiety. No adverse effects were reported, and dropout rates varied between 0% to 52.1%. Yoga was found to be effective in improving mental health and well-being among nursing professionals and students. Yoga mainly reduced stress, anxiety, burnout, and depression, suggesting its potential as a low-cost, accessible intervention for mental health management in this population. Future studies should focus on refining protocols and exploring long-term effects to establish yoga as an integral part of mental health care for nursing professionals and students.

 

Improve Alzheimer’s Disease Symptoms with Yoga Practice

To reduce pre-Alzheimer's cognitive impairment, get to the yoga mat | UCLA

By John M. de Castro, Ph.D.

 

In today’s Research News article “Yoga an integrated mind body intervention for improvement in quality of life in individuals with Alzheimer’s disease and their caregivers” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11968721/) Kaushik and colleagues investigated the effects of a 12-week yoga practice intervention on depression, cognitive abilities and quality of life of patients with Alzheimer’s Disease and the difficulties of caregiving. They report that yoga practice significantly reduced depression and increased cognitive ability and quality of life in the patients and significantly reduced the burden of caregiving.

 

Yoga practice improves the symptoms of patients with Alzheimer’s disease and their caregivers difficulties.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Kaushik M, Yadav A, Upadhyay A, et al. Yoga an integrated mind body intervention for improvement in quality of life in individuals with Alzheimer’s disease and their caregivers. Front Aging. 2025;6:1449485. Published 2025 Mar 21. doi:10.3389/fragi.2025.1449485

 

Abstract

Background and objective

Alzheimer’s disease (AD) presents profound challenges, significantly impairing quality of life (QOL) for patients and increasing the burden on caregivers. This study aims to investigate the effectiveness of a tailored 12-week yoga intervention in improving the quality of life for individuals with mild to moderate AD and reducing caregiver burden (CB).

Methods

This is yoga interventional study with healthy controls enrolled 30 participants (18 males, 12 females) diagnosed with mild to moderate AD by an expert neurologist. Participants were aged 60 years or older and were recruited from an old age home. A 12-week yoga program, including specific postures (asanas), pranayama (breathing exercises), and meditation, was conducted for 1 hour daily, 6 days a week. Neurocognitive assessments were performed pre- and post-intervention using the Geriatric Depression Scale (GDS), Montreal Cognitive Assessment (MoCA), and Caregiver Burden (CB) Scale. MoCA scores were analyzed across specific domains, including language, memory, attention, visuospatial ability, delayed recall, abstraction, and orientation.

Results

The intervention led to significant improvements in quality-of-life measures. GDS scores decreased from 8.36 ± 2.79 to 5.13 ± 3.07 (P < 0.01; 95% CI: −3.98 to −2.31), while MoCA total scores improved from 18.23 ± 4.90 to 21.10 ± 5.09 (P < 0.01; 95% CI: 2.17–3.89). Domain-specific MoCA scores also showed significant enhancements, particularly in language, attention, and delayed recall. Caregiver burden, measured using the CB Scale, demonstrated notable reductions following the intervention (P < 0.01; 95% CI: −2.54 to −1.23).

Conclusion

This study underscores the significant improvements in depression and cognitive function, and overall quality of life in individuals with mild to moderate AD. Additionally, the intervention alleviated caregiver burden, highlighting its potential as an effective mind-body approach for AD management.

 

Postpartum Depression is Improved With Virtual Reality Mindfulness and Yoga Training

Fig. 1

By John M. de Castro, Ph.D.

 

In today’s Research News article “Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11973155/  ) Liu and colleagues examined the effectiveness of virtual reality (VR) enhanced mindfulness meditation and yoga training in comparison to traditional training and a no-training control on the symptoms of postpartum depression. They report that the VR enhanced training produced greater decreases in depression, anxiety, and stress and increases in cognitive control than the traditional training or no-treatment controls.

 

Improve postpartum depression symptoms with virtual reality mindfulness and yoga training.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu N, Deng J, Lu F, Xiao J. Virtual reality enhanced mindfulness and yoga intervention for postpartum depression and anxiety in the post COVID era. Sci Rep. 2025;15(1):11766. Published 2025 Apr 6. doi:10.1038/s41598-025-96165-6

Abstract

The postpartum period has witnessed increasing rates of depression and anxiety, particularly in the context of the COVID-19 pandemic, with these conditions often co-occurring and being exacerbated by the lingering effects of long COVID. Traditional interventions, such as mindfulness-based stress reduction (MBSR) and yoga, have demonstrated effectiveness in alleviating these symptoms. However, the limitations of in-person sessions, especially in the context of pandemic-related restrictions, highlight the need for accessible, innovative approaches. Integrating Virtual Reality (VR) technology with these traditional practices presents a novel solution, offering immersive, customizable environments that may enhance engagement and therapeutic outcomes. This study evaluates the effectiveness of a VR-enhanced mindfulness and yoga intervention in treating postpartum depression and anxiety in women affected by long COVID, with additional examination of underlying physiological stress markers and cognitive control mechanisms. In this randomized controlled trial, 111 postpartum women were randomly assigned to experimental (VR-enhanced intervention), control (traditional in-person sessions), or blank groups using computer-generated randomization. The 8-week intervention involved thrice-weekly 60-minute sessions. Outcomes were assessed at baseline, post-intervention, and 4-week follow-up using the Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder-7 (GAD-7) scale, salivary cortisol measurements, and an emotional Stroop task. The VR-enhanced intervention group demonstrated significant improvements in both depression (EPDS: P < 0.001, ηp2 = 0.18) and anxiety symptoms (GAD-7: P < 0.001, ηp2 = 0.17), with these therapeutic effects significantly greater than those observed in the control and blank groups (P < 0.001 for both comparisons). These improvements were strongly correlated (r = 0.68, P < 0.001). Supporting these primary outcomes, salivary cortisol levels showed a significant decrease (P < 0.001, ηp2 = 0.13), and cognitive control improved as evidenced by reduced emotional Stroop task conflict effect (P < 0.001, ηp2 = 0.37). Correlation analysis revealed robust associations between improvements in depression and anxiety symptoms and changes in physiological markers in both short-term and long-term outcomes. This study demonstrates that integrating VR technology with traditional mindfulness and yoga practices effectively reduces both postpartum depression and anxiety symptoms in the post-COVID era. The parallel improvements in physiological stress markers and cognitive control provide insight into potential mechanisms underlying these therapeutic effects. These findings underscore the value of immersive technology in enhancing traditional therapeutic approaches for addressing postpartum depression and anxiety in the post-pandemic context.

 

Yoga Meditation Improves Mental Health in Female College Students

Why should college students go for Yoga & Meditation? - Blog | Graphic Era

By John M. de Castro, Ph.D.

 

In today’s Research News article “From contemplation to serenity: how yoga meditation improves the mental health of female college students” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11931514/ ) Liu and colleagues studied the effects of yoga meditation on the mental health of female college students. They report that yoga meditation improved the women’s mental health including significantly reduced anxiety, depression, and stress and increased emotional regulation and self-awareness.

 

Improve mental health with yoga meditation.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Liu L, Liu C, Tang L, Wang X, Feng Q. From contemplation to serenity: how yoga meditation improves the mental health of female college students?. Front Psychol. 2025;16:1545943. Published 2025 Mar 10. doi:10.3389/fpsyg.2025.1545943

Abstract

Objective

This study aims to investigate the impact of yoga meditation on the mental health of female college students, focusing on how meditation improves emotional regulation, alleviates stress and strengthens psychological resilience.

Methods

Employing a combination of quantitative assessment and qualitative analysis, the study measured participants’ emotional states, stress levels, and psychological resilience across multiple time points to track participants’ mental health changes dynamically. In-depth interviews and analysis of meditation journals were also conducted.

Results

Yoga meditation significantly reduced anxiety, depression, and perceived stress while enhancing emotional regulation and self-awareness. Meditation positively influenced neuroplasticity, inducing beneficial changes in brain regions associated with emotional control and cognitive flexibility. Additionally, improved autonomic nervous system function was observed, with increased parasympathetic activity and reduced sympathetic response. Meditation strengthened psychological resilience in female college students, improved stress-coping strategies, and sustained positive mental health benefits even after the intervention.

Conclusion

Yoga meditation is an effective mental health intervention, bolstering emotional regulation and reducing stress among female college students. Integrating yoga meditation into campus mental health programs is recommended to provide students with greater practice opportunities and personalized guidance.

Parkinson’s Disease Symptoms are Improved by Meditation or Yoga

Parkinson's Disease | Contemplative Studies

By John M. de Castro, Ph.D.

 

In today’s Research News article “Effects of Meditation and Yoga on Anxiety, Depression and Chronic Inflammation in Patients with Parkinson’s Disease: A Randomized Clinical Trial” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11965853/ ) Kwok and colleagues studied the effects of meditation and yoga practice on the symptoms of Parkinson’s Disease. They found that these practices significantly relieved a wide variety of symptoms, including anxiety, depression, inflammation, movement problems, and improved quality of life.

 

Meditation and yoga relieve the symptoms of Parkinson’s disease.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Jojo Yan Yan Kwok, Lily Man Lee Chan, Charis Ann Lai, Philip Wing Lok Ho, Zoe Yuen-kiu Choi, Man Auyeung, Shirley Yin Yu Pang, Edmond Pui Hang Choi, Daniel Yee Tak Fong, Doris Sau Fung Yu, Chia-chin Lin, Richard Walker, Samuel Yeung Shan Wong, Rainbow Tin Hung Ho. Effects of Meditation and Yoga on Anxiety, Depression and Chronic Inflammation in Patients with Parkinson’s Disease: A Randomized Clinical Trial. Psychother Psychosom. 2025 Feb 28;94(2):101–118.

Abstract

Introduction

Clinical guidelines recommend a holistic approach to Parkinson’s disease (PD) care, yet randomized trials examining mindfulness-based interventions in this context are scarce. This study investigated the effects of two mindfulness practices – meditation and yoga – on biopsychosocial outcomes in PD patients, including anxiety symptoms, depressive symptoms, motor/nonmotor symptoms, health-related quality-of-life (HRQOL), mindfulness, and stress and inflammation biomarkers, compared to usual care.

Methods

159 participants with a clinical diagnosis of idiopathic PD and a Hoehn and Yahr stage of 1, 2, and 3, were randomized into meditation (n = 53), yoga (n = 52), and control (n = 54). Meditation and yoga were delivered in 90-min groups for 8 weeks. Primary outcomes included anxiety symptoms and depressive symptoms. Secondary outcomes included motor and nonmotor symptoms, HRQOL, mindfulness, and serum levels of interleukin-6, cortisol and TNF-alpha. Assessments were done at baseline (T0), 2 months (T1), and 6 months (T2). Linear mixed models were conducted following intention-to-treat principle.

Results

Compared to control, both meditation, and yoga groups had significant improvements in anxiety symptoms (meditation: mean difference [MD] = −1.36, 95% CI: −2.46 to−0.26; yoga: MD = −1.61, CI: −2.70 to −0.52), motor symptoms (meditation: MD = −5.35, CI: −8.61 to−2.09; yoga: MD = −6.59, CI: −9.82 to−3.36), HRQOL (meditation: MD = −2.01, CI: −3.41 to−0.62; yoga: MD = −1.45, CI: −2.83 to−0.08), and describing skills (meditation: MD = 0.97, CI: 0.04–1.89; yoga: MD = 0.92, CI: 0.01–1.84) at T1, and significant reductions in serum interleukin-6 levels (meditation: MD = −1.14, CI: −2.18 to−0.10; yoga: MD = −1.11, CI: −2.09 to−0.13) at T2. Only meditation significantly reduced depression (MD = −1.44, CI: −2.57 to−0.30) at T1 and sustained the motor and HRQOL improvements at T2.

Conclusion

Meditation and yoga significantly improved anxiety symptoms, chronic inflammation, motor symptoms, mindfulness-describing facet, and HRQOL in PD patients. Meditation provided additional benefits in reducing depressive symptoms and sustaining motor and HRQOL improvements.

 

Yoga is Associated with Lower Rates of Multimorbidity in Adults over 45

Flexibility exercises, like yoga, can help maintain mobility as you age.

By John M. de Castro, Ph.D.

 

In today’s Research News article “Association between yoga and multimorbidity: a nationwide study of 279,885 middle-aged and older adults” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11884150/ ) Wang and colleagues examined practice of yoga and the likelihood of adults over 45 years of age having multiple diseases, including obesity, diabetes, hyperlipidemia, and hypertension. They found that the higher the duration and frequency of yoga practice the less the likelihood that the adult will have multiple diseases simultaneously.

 

Yoga practice is associated with lower risk of multimorbidity in older adults.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Wang K, Wang P, Li Y, Wang C, Veldheer S, Wang F, Na M, Sun L, Gao X. Association between yoga and multimorbidity: a nationwide study of 279,885 middle-aged and older adults. BMC Public Health. 2025 Mar 6;25(1):888. doi: 10.1186/s12889-025-22035-5. PMID: 40050815; PMCID: PMC11884150.

Abstract

Background

The health benefits of exercise have been well-established, but the specific role of yoga in multimorbidity was less understood. This study aimed to examine the association between yoga and multimorbidity in comparison with other exercises or non-exercise.

Methods

This cross-sectional study pooled nationally representative surveys from Behavioral Risk Factor Surveillance System (BRFSS) (2015, 2017, and 2019), and classified 279,885 participants aged 45 + years as yoga practitioners, other exercisers, and non-exercisers. Multinominal and binary logistic regressions were separately used for association of yoga with multimorbidity (coexistence of ≥ 2 conditions) and individual chronic conditions. Potential effect modification by age, sex, education level, and race/ethnicity was examined. We further assessed the dose-response association of duration and frequency of yoga practice with multimorbidity.

Results

The adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for yoga practitioners (n = 5081) vs. other exercisers (n = 192,718) were 0.69 (95% CI 0.55–0.86) for coexistence of two conditions, and 0.72 (95%CI 0.58–0.89) for coexistence of ≥ 3 conditions. The associations were stronger (ORs ranged from 0.43 to 0.52; P < 0.0001 for all) when comparing yoga practitioners with non-exercisers (n = 82,086), which were more pronounced in women relative to men (P-interaction < 0.05). Increased duration or frequency of yoga practice was associated with lower odds of multimorbidity in a dose-response manner (P for trend<0.0001 for all). Similar inverse associations were observed between yoga and individual chronic conditions.

Conclusion

Yoga was associated with lower odds of multimorbidity in middle-aged and older adults, relative to other exercises or non-exercise.

 

Yoga improves physiological and psychological states

Yoga for Exercise - The Nutrition Source

By John M. de Castro, Ph.D.

 

In today’s Research News article “Long-term effects of yoga-based practices on neural, cognitive, psychological, and physiological outcomes in adults: a scoping review and evidence map.” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11884082/ ) Campelo and colleagues review and summarize the effects of long-term yoga practice on the physiological and psychological states of yoga practitioners. They report that yoga practice produces long-term changes in brain systems underlying sensorimotor, interoceptive, emotion regulation, and executive functions and in the periphery increases in parasympathetic-driven autonomic, hormonal and immune responses. Yoga practice also reduces negative emotions, psychopathology, and emotional reactivity as well as improved memory and cognition.

 

Long-term yoga practice positively alters the physiological and psychological state of the practitioners.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Campelo G, de Araújo JR, Aristizabal JP, de Souza W, de Castilho GM. Long-term effects of yoga-based practices on neural, cognitive, psychological, and physiological outcomes in adults: a scoping review and evidence map. BMC Complement Med Ther. 2025 Mar 6;25(1):92. doi: 10.1186/s12906-025-04825-x. PMID: 40050913; PMCID: PMC11884082.

 

Abstract

Background

Compared with short-term practices, long-term yoga might promote differential qualitative and quantitative outcomes. Following JBI’s and PRISMA-ScR guidelines, this scoping review followed an apriori and systematic protocol to document the long-term effects of yoga on neural, cognitive, psychological, and physiological outcomes, provide evidence maps for each yoga component, and summarize results identifying knowledge gaps and promising directions.

Methods

Four databases (PubMed, Cochrane, LILACS, and PubPsych) were last searched in March 2023. Studies were included if they evaluated adults with > 1 year of practice, specified yoga-based practice(s) of interest, measured neural, cognitive, psychological, and/or physiological outcomes, were written in English, Spanish, or Portuguese, presented original data, and mentioned search terms in the title/abstract. Evidence maps for each yoga component followed a 4-level structure of outcome category, method, study design and literature size. Qualitative summaries followed the same structure, to facilitate information retrieval.

Results

Out of 2270 screened studies, 65 were included (meditative studies = 36, predominantly postural studies = 25, breathing practice studies = 8). Physiologicaland neural outcomes were the most common, followed by psychological and cognitive outcomes. Although heterogeneous, neural results reveal structural and functional changes related to sensorimotor, interoceptive, emotion regulation, and executive functions. Physiologically, most studies have associated long-term practice with parasympathetic-driven autonomic, hormonal and immune responses, but some studies revealed sympathetic-driven or mixed responses, maybe due to the specific technique or individual differences. Psychological outcomes included lower levels of negative affect, psychopathological symptoms, and emotional reactivity. Cognitive measures have shown improved memory/cognition for older adults, but mixed or null effects for other constructs. Commonly, however, long-term practitioners demonstrated improved neural or physiological efficiency while performing cognitive tasks.

Conclusions

Future research should provide clear descriptions of the investigated yoga practice, employ more experimental paradigms, and refine statistical reports and models. We encourage researchers to work with specific overarching theoretical frameworks to refine research predictions, such as the neurovisceral integration model or predictive coding models; to consider motivational, cultural, and contextual factors that might influence long-term outcomes; and to develop systematic reviews and meta-analyses as next steps of evidence summary.

 

Yoga Reduces Inflammation in Breast Cancer Patients

Living Beyond Breast Cancer Yoga Series Part 1By John M. de Castro, Ph.D.

 

In today’s Research News article “Yoga Intervention and Inflammatory Homoeostasis in Breast Cancer Patients” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11866663/ ) Kaje and colleagues provided a 3-days yoga intervention to patients undergoing chemotherapy for breast cancer. They found that the yoga practice reduced the levels of inflammatory markers in the patients.

 

Yoga decreased inflammation in patients undergoing chemotherapy for breast cancer.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Kaje KC, Dsilva F, Shetty PK, Mohan R, Kumar S, Dsouza N, D’souza C, Kalladka SS, Alagundagi DB, Kalladka K. Yoga Intervention and Inflammatory Homoeostasis in Breast Cancer Patients. Indian J Palliat Care. 2025 Jan-Mar;31(1):1–7. doi: 10.25259/IJPC_181_2024. Epub 2025 Feb 15. PMCID: PMC11866663.

Abstract

Objectives:

Yoga, renowned for its ability to maintain physical, mental and spiritual well-being, has recently gained prominence as a supportive therapy during conventional breast cancer (BC) treatment. This paradigm shift reflects a growing trend of people embracing yoga to enhance their overall health and aid in managing BC. The objective of this study was to determine the yoga intervention and inflammatory homoeostasis in newly diagnosed BC patients.

Materials and Method:

This study recruited 44 newly diagnosed BC patients at stages II, III and IV (without distant metastasis or other inflammatory diseases), all admitted for neoadjuvant chemotherapy followed by surgery. A prospective non-randomised control design was employed. Baseline assessments were conducted before the first chemotherapy cycle, with follow-ups before the 2nd and 3rd chemotherapy cycles, before surgery, and 2 months post-surgery. The outcome was compared with the control group.

Results:

The study showed significant within-subject effects in the yoga intervention group on serum tumour necrosis factor-alpha, interleukin (IL)-1-beta and IL-6 levels, while no significant changes were observed in the control group. Although between groups did not show statistically significant, the mean values indicated a consistent downregulation of proinflammatory markers over time in the yoga group.

Conclusion:

Incorporating yoga as a complementary therapy alongside conventional BC treatment significantly improved the health outcomes of BC patients by modulating proinflammatory markers.