Mindfulness

Reduce the Depressive Effects of Adverse Childhood Experiences with Mindfulness

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Reduce the Depressive Effects of Adverse Childhood Experiences with Mindfulness

 

By John M. de Castro, Ph.D.

 

“mindfulness instruction may mitigate the negative effects of stress and trauma related to adverse childhood exposures, improving short- and long-term outcomes, and potentially reducing poor health outcomes in adulthood.” – Robin Ortiz

 

Childhood trauma can leave in its wake symptoms which can haunt the victims for the rest of their lives. These include persistent recurrent re-experiencing of the traumatic event, including flashbacks and nightmares, loss of interest in life, detachment from other people, increased depression, anxiety and emotional arousal, including outbursts of anger, difficulty concentration, and jumpiness, startling easily. Unfortunately, childhood maltreatment can continue to affect mental and physical health throughout the individual’s life. How individuals cope with childhood maltreatment helps determine the effects of the maltreatment on their mental health.

 

It has been found that experiencing the feelings and thoughts produced by trauma completely, allows for better coping. This can be provided by mindfulness. Indeed, mindfulness has been found to be effective for relieving trauma symptoms. But it is not known how mindfulness interacts with adverse childhood experiences to impact psychological well-being later on.

 

In today’s Research News article “Mindfulness as a mediator and moderator in the relationship between adverse childhood experiences and depression.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215089/ ) McKeen and colleagues recruited college students and had them complete measures of mindfulness, adverse childhood experiences, and depression. Adverse childhood experiences included instances of physical or emotional abuse and family dysfunction. Of the students 71% reported some form of adverse childhood experiences.

 

They found that the greater the adverse childhood experiences the higher the levels of depression and the lower the levels of mindfulness, especially the describing, acting with awareness, and non-judging facets. They also found that the higher the levels of mindfulness the lower the levels of depression. Further they found that mindfulness moderated the relationship of adverse childhood experiences with depression such that the greater the level of adverse childhood experiences the lower the levels of mindfulness and in turn the lower the levels of depression.

 

The results of the present study are correlational and so no conclusions can be reached regarding causation. Previous research by others, however, has demonstrated a causal connection between mindfulness and lower depression. So, the observed relationship here is likely due to mindfulness causing a reduction in depression.

 

It has also been previously observed that adverse childhood experiences are associated with lower mindfulness and well-being.  What is new here is the demonstration that adverse childhood experiences are linked to depression by reduced mindfulness. This suggests that mindfulness training may be a means to reduce depression caused by adverse childhood experiences.

 

So, reduce the depressive effects of adverse childhood experiences with mindfulness.

 

“Numerous studies support the use of mindfulness as an effective intervention for youth exposed to trauma.” – Jennifer Peterson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

 

Study Summary

 

McKeen, H., Hook, M., Podduturi, P., Beitzell, E., Jones, A., & Liss, M. (2021). Mindfulness as a mediator and moderator in the relationship between adverse childhood experiences and depression. Current psychology (New Brunswick, N.J.), 1–11. Advance online publication. https://doi.org/10.1007/s12144-021-02003-z

 

Abstract

Adverse childhood experiences (ACEs) have been associated with a variety of negative physical and psychological health outcomes. The mechanisms by which this occurs and potential protective factors present in this relationship are understudied. Mindfulness is a cognitive resource that may protect individuals against symptoms of psychological distress. It has five core facets and encourages a nonjudgmental acceptance of the present moment. The purpose of this study was to explore the role of mindfulness in the relationship between ACEs and depression, both as a mediator and as a moderator, or protective factor. We hypothesized that the aware, describe, and non-judgement facets of mindfulness would be key factors in both sets of analyses. Participants at a university (N = 279) were given the Five Factor Mindfulness Questionnaire (FFMQ), the Adverse Childhood Experiences Scale (ACES), and the Patient Health Questionnaire (PHQ-8) to measure depression. Results indicated that the describe CI [.02, .11], aware CI [.05, .17], and non-judgement CI [.06, .18] facets of mindfulness significantly mediated the relationship between ACEs and depression. Additionally, the aware facet of mindfulness was also a significant moderator in this relationship, [t (interaction) = −3.22, p < 0.01], such that individuals with a high level of awareness had no increase in depression even as the number of ACEs increased. Negative cognitions associated with ACEs may harm one’s ability to effectively describe their feelings and to be fully aware of the present moment, which may contribute to symptoms of depression. Implications for mindfulness-based interventions (MBIs) are discussed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215089/

 

Reduce Stress and Improve Well-Being in Nursing Students with Mindfulness

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Reduce Stress and Improve Well-Being in Nursing Students with Mindfulness

 

By John M. de Castro, Ph.D.

 

“mindfulness meditation has a positive impact on nurses’ and nursing students’ stress, anxiety, depression, burnout, sense of well-being and empathy.” – Pamela van der Riet

 

Stress is epidemic in the western workplace with almost two thirds of workers reporting high levels of stress at work. In high stress occupations, like healthcare, burnout is all too prevalent. It is estimated that over 45% of healthcare workers experience burnout. Burnout not only affects the healthcare providers personally, but also the patients, as it produces a loss of empathy and compassion. So, preventing burnout has to be a priority.

 

It is important that methods be found to reduce the individual’s responses to stress and to improve their resilience. Contemplative practices have been shown to reduce the psychological and physiological responses to stress. Indeed, mindfulness has been shown to be helpful in treating and preventing burnout, increasing resilience, and improving sleep. Developing mindfulness early in healthcare careers could work to prevent later burnout. There has been considerable research on this topic. So, it makes sense to summarize what has been learned regarding the effects of mindfulness training for nursing students.

 

In today’s Research News article “Mindfulness-Based Interventions for Undergraduate Nursing Students in a University Setting: A Narrative Review.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621067/ ) McVeigh and colleagues review and summarize the published research on the effectiveness of mindfulness training on the psychological well-being of nursing students. They identified 15 published research studies.

 

They report that the published research found that mindfulness training for nursing students resulted in significant decreases in anxiety, depression, perceived stress, and negative coping strategies, and significant increases in mindfulness, self-efficacy, emotion regulation, and self-awareness. These benefits accrued regardless of the type and form of mindfulness training from meditation, to Mindfulness-Based Stress Reduction (MBSR), to mindful movement practice.

 

These results are very promising. Mindfulness training of nursing students appears to markedly improve their psychological well-being. There was no long-term follow-up reported. So, it is not known whether the training has lasting effects and potentially improve resilience to later career stresses and reduce burnout. Future research needs to follow-up to identify whether the effects of this early intervention might assist the nurses in their later careers.

 

So, reduce stress and improve well-being in nursing students with mindfulness.

 

“Mindfulness practices have been found beneficial for nurses. The program has been found to increase self-compassion, serenity, and empathetic concern as well as decrease burnout and self-reported distress “ – Sandra Bernstein

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available at the Contemplative Studies Blog http://contemplative-studies.org/wp/ andon Twitter @MindfulResearch

 

Study Summary

 

McVeigh, C., Ace, L., Ski, C. F., Carswell, C., Burton, S., Rej, S., & Noble, H. (2021). Mindfulness-Based Interventions for Undergraduate Nursing Students in a University Setting: A Narrative Review. Healthcare, 9(11), 1493. https://doi.org/10.3390/healthcare9111493

 

Abstract

(1) Introduction: Undergraduate (UG) nursing students are vulnerable to stress throughout their education, known to result in burnout, with high attrition rates of up to 33%. There is a growing body of evidence to suggest that mindfulness-based interventions are effective for the management of anxiety, depression and wellbeing, thereby reducing stress in healthcare provider populations. The aim of this narrative review was to synthesize and provide a critical overview of the current evidence in relation to mindfulness-based interventions for UG nursing students in a university setting. (2) Methods: A review of the literature was conducted in March 2020 and updated in May 2021, utilising the databases CINAHL, Medline and PsycINFO. (3) Results: Fifteen studies were included in the review, with three common themes identified: (i) the positive impact of mindfulness on holistic wellbeing, (ii) mindfulness-based techniques as a positive coping mechanism within academic and clinical practice, and (iii) approaches to the delivery of mindfulness-based interventions. (4) Conclusions: Mindfulness-based interventions are effective strategies for the management of stress, development of self-awareness and enhanced academic and clinical performance in undergraduate nursing students. No ideal approach to delivery or duration of these interventions was evident from the literature. Best practice in relation to delivery of mindfulness-based interventions for nursing students is recommended for future studies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621067/

 

Improve Emotion Regulation and Well-Being During Covid-19 with Mindfulness

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Improve Emotion Regulation and Well-Being During Covid-19 with Mindfulness

 

By John M. de Castro, Ph.D.

 

“A mindfulness practice can help us connect with awareness and let things come and go without our attention getting stuck on it. It can also help us make better choices. Between the emotion and the action, there is a choice, so this can help you to respond rather than to react.” – Anne Dutton

 

Mindfulness training has been shown to improve health and well-being in healthy individuals. It has also been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. The COVID-19 pandemic has challenged the mental and physical health of the population. It has created intense stress both for frontline workers but also for people simply isolating at home. So, there is a need to find ways to improve psychological well-being during the pandemic.

 

Mindfulness is known to decrease the psychological and physical responses to stress. So, mindfulness training may be helpful in coping with the mental and physical challenges resulting from the COVID-19 pandemic. But exposure to others during a pandemic is very dangerous. So, providing mindfulness training online is a preferred method. Mindfulness-Based Stress Reduction (MBSR) is a well-established and heavily used mindfulness training technique that employs meditation, body scan, yoga, group discussion and homework. It has been successfully implemented online. But it’s efficacy during a Covid-19 lockdown is not well established.

 

In today’s Research News article “Mindfulness-Based Stress Reduction Increases Mental Wellbeing and Emotion Regulation During the First Wave of the COVID-19 Pandemic: A Synchronous Online Intervention Study.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.720965/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1778822_a0P58000000G0YfEAK_Psycho_20211123_arts_A ) Sanilevici and colleagues during the first wave Covid-19 lockdown recruited adult participants who enrolled in an online Mindfulness-Based Stress Reduction (MBSR) course and a control group who expressed interest in the online program but who were unable to participate. MBSR was administered in 8 weekly, 2.5 hour online meetings along with 30 minutes of daily home practice. The groups were measured before and after MBSR and 1 month later for mindfulness, anxiety, perceived stress, emotion regulation, intolerance of uncertainty, and loneliness.

 

At baseline they found that the higher the levels of mindfulness the lower the levels of anxiety, perceived stress, intolerance of uncertainty, and loneliness and the higher the levels of emotion regulation. They also found that in comparison to baseline and the control group, the group that completed the online Mindfulness-Based Stress Reduction (MBSR) course had significantly lower levels of anxiety and perceived stress and significantly higher levels of emotion regulation. Finally, they found that MBSR lowered anxiety and perceived stress directly and also indirectly by increasing emotion regulation which in turn lowered anxiety and perceived stress. These benefits were still significant one month after the completion of MBSR.

 

Previous research by others has established that mindfulness training reduces anxiety and perceived stress and improves emotion regulation. The present findings suggest that a Mindfulness-Based Stress Reduction (MBSR) course can be successfully implemented online, improving the psychological well-being of individuals during an extremely stressful time. They further demonstrate that MBSR improved psychological well-being directly and through improving emotion regulation. These findings are important as during a pandemic it is not feasible to provide mindfulness-based therapy in person. So, the findings that mindfulness training can be implemented successfully online improving the psychological well-being of individuals in the real world provides a means to help individuals cope with the pandemic and the lockdown.

 

So, improve emotion regulation and well-being during Covid-19 with mindfulness.

 

“Mindfulness practice . . . can bring about an understanding and acceptance of transient and ever-changing nature of all our experiences, whether mental (thoughts, emotions, body sensations) or physical (events, things, relationships). This experiential understanding of all phenomena as being “impermanent” might prove to be an important mechanism for promoting positive adaptation to a highly unpredictable and constantly changing landscape of COVID-19 pandemic.” – Elena Antonova

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

 

Study Summary

 

Sanilevici M, Reuveni O, Lev-Ari S, Golland Y and Levit-Binnun N (2021) Mindfulness-Based Stress Reduction Increases Mental Wellbeing and Emotion Regulation During the First Wave of the COVID-19 Pandemic: A Synchronous Online Intervention Study. Front. Psychol. 12:720965. doi: 10.3389/fpsyg.2021.720965

 

The COVID-19 pandemic imposed extreme living conditions of social distancing, which triggered negative mental health problems and created challenges in seeking mental health support. Mindfulness-based interventions (MBIs) have been found to enhance wellbeing and mental health by reducing stress and anxiety and improving emotion regulation. Preliminary evidence suggests that online, synchronous MBIs may produce beneficial effects similar to face-to-face programs. However, the effectiveness of such online-MBIs to support mental health in highly stressful times, such as a global pandemic, requires further study. To this end, we investigated the effect of an online 8-week Mindfulness-Based Stress Reduction (MBSR) program on aspects of mental health during the first wave of the COVID-19 pandemic. Participants (N=92) who expressed interest in discounted online-MBSR programs were recruited for the study. The division into experimental and control groups was based on actual enrollment to the courses. Those who enrolled in a program were assigned to the experimental condition and those who decided not to enroll served as controls. Participants were assessed pre-intervention, post-intervention, and 1-month post-intervention for levels of mindfulness, perceived stress, anxiety, emotion regulation, and intolerance of uncertainty. Differences between the groups were tested using the general linear mixed effects model (GLMM) and Individual Growth Curve Models (IGCM) in intent to treat analysis. The findings indicated that, relative to the control group, MBSR improved mindfulness abilities (p <0.001), decreased anxiety (p <0.001), and stress (p <0.001) and increased emotion regulation (p <0.001). These effects were found to persist 1 month after the end of the program, despite the increased governmental public-health restrictions due to COVID-19 at that time. The ability to tolerate uncertainty, a central characteristic of the pandemic, was not found to be affected by the program. A mediation analysis revealed that the effect of the intervention on mental health improvement was partially mediated by the improvement in emotion regulation. Overall, the findings provide positive evidence for the feasibility of an online-MBSR program to support the mental health of individuals from the general population through the mediation of emotion regulation in challenging times, such as a global pandemic.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.720965/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1778822_a0P58000000G0YfEAK_Psycho_20211123_arts_A

 

Improve Cognitive and Socio-Emotional Skills in Children with Mindfulness

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Improve Cognitive and Socio-Emotional Skills in Children with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Teaching mindfulness to kids can also help shape three critical skills developed in early childhood: paying attention and remembering information, shifting back and forth between tasks, and behaving appropriately with others.” – Christopher Willard

 

Childhood is a miraculous period during which the child is dynamically absorbing information from every aspect of its environment. This is particularly evident during the elementary school years. Mindfulness training in school has been shown to have very positive effects. These include improvements in the cognitive, psychological, emotional and social domains. Importantly, mindfulness training in school appears to improve attentional ability which is fundamental to success in all aspects of academic performance. The research evidence has been accumulating. So, there is a need to summarize what has been learned.

 

In today’s Research News article “Exploring the Effects of Meditation Techniques Used by Mindfulness-Based Programs on the Cognitive, Social-Emotional, and Academic Skills of Children: A Systematic Review.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.660650/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1778822_a0P58000000G0YfEAK_Psycho_20211123_arts_A ) Filipe and colleagues review and summarize the published controlled research studies on the effects of mindfulness training on 6-12 year old children. They found 29 published research articles.

 

They report that the published research found that mindfulness training produced significant improvements in the children’s cognitive skills, including overall executive functions, attention, concentration, inhibitory control, cognitive flexibility, and immediate auditory-verbal memory. They also found that there were significant improvements in socio-emotional skills, including stress, wellbeing, mindfulness, self-esteem, resilience, psychological happiness, empathy, perspective-taking, emotional control, optimism, depression, internalizing problems, peer aggression, prosocial behavior, peer acceptance, anxiety, self-control, self-regulation, mental health problems, quality of life, self-compassion, acceptance, relaxation, happiness, aggressive behaviors, and social competence. But only one of the 29 studies reported improvements in academic skills.

 

The published research makes a strong case for the effectiveness of mindfulness training to improve the cognitive and socio-emotional skills on children. But there is little evidence for improvement in academic performance. Unfortunately, only 9 of the 29 studies employed strong research designs (randomized controlled trails). So, there is a need for further research with high quality research designs. Nevertheless, the consistency and magnitude of the findings suggest robust positive effects of mindfulness trainings on a myriad of cognitive, social, and emotional skills in children. These are important benefits for these developing humans that may have important contributions to their growth and well-being, perhaps eventually making them better adults. As such, mindfulness training should be incorporated into the school curriculum.

 

So, improve cognitive and socio-emotional skills in children with mindfulness.

 

“For children, mindfulness can offer relief from whatever difficulties they might be encountering in life. It also gives them the beauty of being in the present moment.” – Annaka Harris

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

 

Study Summary

 

Filipe MG, Magalhães S, Veloso AS, Costa AF, Ribeiro L, Araújo P, Castro SL and Limpo T (2021) Exploring the Effects of Meditation Techniques Used by Mindfulness-Based Programs on the Cognitive, Social-Emotional, and Academic Skills of Children: A Systematic Review. Front. Psychol. 12:660650. doi: 10.3389/fpsyg.2021.660650

 

There is evidence for the positive impact of mindfulness in children. However, little is known about the techniques through which mindfulness practice results in differential outcomes. Therefore, this study intended to systematically review the available evidence about the efficacy of meditation techniques used by mindfulness-based programs on cognitive, socio-emotional, and academic skills of children from 6 to 12 years of age. The review was registered on the PROSPERO database, and the literature search was conducted according to PICO criteria and PRISMA guidelines. The EBSCO databases were searched, and 29 studies were eligible: nine randomized controlled trials and 20 quasi-experimental studies. All the included randomized controlled trials were rated as having a high risk of bias. Overall, the evidence for mindfulness techniques improving cognitive and socio-emotional skills was reasonably strong. Specifically, for cognitive skills, results showed that all the interventions used “body-centered meditations” and “mindful observations.” Regarding socio-emotional skills, although all the studies applied “body-centered meditations” and “mindful observations,” “affect-centered meditations” were also frequent. For academic skills, just one quasi-experimental trial found improvements, thus making it difficult to draw conclusions. Further research is crucial to evaluate the unique effects of different meditation techniques on the cognitive, social-emotional, and academic skills of children.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.660650/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1778822_a0P58000000G0YfEAK_Psycho_20211123_arts_A

Increase Brain Grey Matter with Mindfulness

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Increase Brain Grey Matter with Mindfulness

 

By John M. de Castro, Ph.D.

 

“meditating can give you the brain of a 25-year-old. Too bad it can’t also give you the body of one.” – Melanie Curtain

 

Mindfulness training has been shown through extensive research to be effective in improving physical and psychological health and particularly with reducing the physical and psychological reactions to stress. There are a number of ways that meditation practices produce these benefits, including changes to the brain and physiology. The nervous system changes in response to how it is used and how it is stimulated in a process called neuroplasticity. Highly used areas grow in size, metabolism, and connectivity. Mindfulness practices in general are known to produce these kinds of changes in the structure and activity of the brain. The research has been accumulating and there is a need to summarize what has been learned.

 

In today’s Research News article “Mindfulness related changes in grey matter: a systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500886/ ) Pernet and colleagues review, summarize, and perform a meta-analysis of the published research on the effects of mindfulness practices on the amount of grey matter in the brain and brain structures.

 

They identified 25 published research studies that included a total of 1406 participants. They report that the published research found that meditation practice produced an enlargement of the insular cortex. There was also increased functional connectivity between the insular cortex and the cingulate cortex and the paracingulate gyrus. They note that there was great variation in the studies in terms of other structures showing increases in size and connectivity but little commonality. The studies, however, very greatly in procedure, meditation practice and experience, participant types, and numbers, etc. So, they recommend that future studies be more standardized and with larger numbers of participants.

 

With this heterogeneity of studies, finding that the insular cortex is expanded in most highlights its importance in meditation effects on the brain. The insular cortex is a highly connected structure of the brain that is so interconnected with multiple other brain areas that it has been thought of as a hub. It has been implicated in interoception, multimodal sensory processing, autonomic control, perceptual self-awareness, and emotional guidance of social behavior. This makes sense as meditation practice involves the perception of the internal state derived from multiple sensory experiences and, of course, self-awareness. The research findings suggest that meditation produces neuroplastic changes in the brain that are reflective of the mental states occurring in meditation. This, in turn, likely makes the practitioner more sensitive to these mental states.

 

So, increase brain grey matter with mindfulness.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

 

“mindfulness meditation induces gray matter plasticity, suggesting that structural changes in ventral PCC—a key hub associated with self-awareness, emotion, cognition, and aging—may have important implications for protecting against mood-related disorders and aging-related cognitive declines.” – Rongxiang Tang,

 

Study Summary

 

Pernet, C. R., Belov, N., Delorme, A., & Zammit, A. (2021). Mindfulness related changes in grey matter: a systematic review and meta-analysis. Brain imaging and behavior, 15(5), 2720–2730. https://doi.org/10.1007/s11682-021-00453-4

 

Abstract

Knowing target regions undergoing strfuncti changes caused by behavioural interventions is paramount in evaluating the effectiveness of such practices. Here, using a systematic review approach, we identified 25 peer-reviewed magnetic resonance imaging (MRI) studies demonstrating grey matter changes related to mindfulness meditation. An activation likelihood estimation (ALE) analysis (n = 16) revealed the right anterior ventral insula as the only significant region with consistent effect across studies, whilst an additional functional connectivity analysis indicates that both left and right insulae, and the anterior cingulate gyrus with adjacent paracingulate gyri should also be considered in future studies. Statistical meta-analyses suggest medium to strong effect sizes from Cohen’s d ~ 0.8 in the right insula to ~ 1 using maxima across the whole brain. The systematic review revealed design issues with selection, information, attrition and confirmation biases, in addition to weak statistical power. In conclusion, our analyses show that mindfulness meditation practice does induce grey matter changes but also that improvements in methodology are needed to establish mindfulness as a therapeutic intervention.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500886/

Mindfulness is Associated with a Reduced Tendency to Ostracize

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Mindfulness is Associated with a Reduced Tendency to Ostracize

 

By John M. de Castro, Ph.D.

 

“adults scoring higher on trait mindfulness reported ostracizing coworkers less [and] demonstrated greater inclusion of a fellow group member being ostracized by others in the group.“ – Eric Jones

 

Humans are social animals. This is a great asset for the species as the effort of the individual is amplified by cooperation. In primitive times, this cooperation was essential for survival. But in modern times it is also essential, not for survival but rather for making a living and for the happiness of the individual. This deep need for positive social interactions heightens the pain of social rejection and ostracism. “Ostracism, or being excluded and ignored, is a detrimental experience for the target of ostracism because it harms the target’s relational needs of belonging, self-esteem, meaningful existence, and control, along with worsening the target’s mood.”

 

Mindfulness has been found to increase prosocial behaviors such as altruism, compassion and empathy and reduce antisocial behaviors such as violence and aggression. So, it is likely that mindfulness may affect the individual’s tendency to reject and ostracize others.

 

In today’s Research News article “Who Is Less Likely to Ostracize? Higher Trait Mindfulness Predicts More Inclusionary Behavior.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277536/ ) Jones and colleagues studied the relationship of mindfulness to ostracism in 3 studies. For all studies they recruited healthy adult workers online.

 

In the first study they had them complete measures of mindfulness, perceived ostracism, perceived stress, and instigation of ostracism. They found that the higher the levels of mindfulness the lower the levels of perceived ostracism, perceived stress, and instigation of ostracism. So, mindful workers are more sensitive to ostracism in the workplace and less likely to be involved in ostracism.

 

In the second study they had the participants play a simulated ball tossing game, Cyberball, where they tossed a ball to 3 other participants who were simulated did not exist other than in the program. In one condition the ball was tossed to all participants equally and in the ostracism condition one simulated participant had the ball tossed to them initially but then never again from anyone except the real participant who could toss the ball to the ostracized participant if they chose. They found that the higher the level of participant mindfulness the greater the proportion of simulated ball tosses were directed to the simulated “ostracized” participant. Neither empathy, personal distress, nor the other motives were found to mediate the effects of mindfulness.

 

In the third study they again had the participants play Cyberball with an ostracized simulated participant. There were 2 conditions in that the participants were either instructed at the beginning to pay attention to the other players or did not receive the attention instruction. They found that the attention instruction increased the percentage of tosses directed to the simulated “ostracized” participant. In the attention instruction condition the effects of mindfulness disappeared.

 

The results suggest that high trait mindfulness is associated with less ostracizing of others in their work environments. The simulated ball tossing results suggested that mindfulness is also associated with lower ostracizing in artificial simulated conditions. But when an attention instruction is included the association with mindfulness goes away. This suggests that mindfulness results in a participant paying more attention to others around them and this produces a lowered tendency to ostracize others.

 

Ostracism is extremely harmful to individuals. So, methods to reduce ostracism are socially important. The results suggest that mindfulness may be an effective tool in countering ostracism by making individuals more attentive to others. It remains for future research to determine if training in mindfulness can reduce ostracism.

 

So, mindfulness is associated with a reduced tendency to ostracize.

 

“dispositional mindfulness predicted greater empathic concern for, and more helping behavior toward, an ostracized stranger [and] also promoted prosocial responsiveness to an ostracized stranger.“ – Daniel Berry

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Jones, E. E., Wirth, J. H., Ramsey, A. T., & Wynsma, R. L. (2019). Who Is Less Likely to Ostracize? Higher Trait Mindfulness Predicts More Inclusionary Behavior. Personality & social psychology bulletin, 45(1), 105–119. https://doi.org/10.1177/0146167218780698

 

Abstract

Despite the pain ostracism (being excluded and ignored) causes, researchers have minimally investigated factors related to reducing its occurrence. We investigated the association between higher trait mindfulness (the tendency to be attentive to the present moment) and lower engagement in ostracism. In Study 1, employed adults scoring higher on trait mindfulness reported ostracizing coworkers less. In Study 2, participants possessing higher levels of trait mindfulness demonstrated greater inclusion of a fellow group member being ostracized by others in the group. Results suggested that attention, rather than empathy, was the psychological process responsible for greater inclusion of an ostracized group member by mindful individuals. Study 3 supported this conclusion, because participants responded similarly to those high in trait mindfulness when they were instructed to pay attention and ensure all players were included equally. Overall, we found that people with higher levels of trait mindfulness are more attentive to targets of ostracism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277536/

 

Improve Teachers’ Physiological and Psychological Well-Being with Mindfulness

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Improve Teachers’ Physiological and Psychological Well-Being with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness-based training can effectively reduce stress and burnout as well as symptoms of anxiety and depression at follow-up; it also shows promise in improving emotional regulation among teachers.” – Xiaolan Song

 

Stress is epidemic in the workplace with almost two thirds of workers reporting high levels of stress at work. This often produces burnout; fatigue, cynicism, emotional exhaustion, and professional inefficacy. In a school setting, this burnout and exhaustion not only affects teachers personally, but also the students and schools, as it produces a loss of enthusiasm, empathy, and compassion. Hence, there is a need to identify methods of reducing stress and improving teachers’ psychological health. Mindfulness has been demonstrated to be helpful in reducing the psychological and physiological responses to stress and for treating and preventing burnout. This suggests that mindfulness would improve the psychological and physiological well-being of teachers,

 

In today’s Research News article “Mindfulness meditation training effects on quality of life, immune function and glutathione metabolism in service healthy female teachers: A randomized pilot clinical trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566766/ ) Rodrigues de Oliveira and colleagues recruited healthy teachers and randomly assigned them to receive 8 weekly 2-hour sessions of either mindfulness training or lectures on applied neuroscience for educators. Mindfulness training included “mindful breathing, compassionate communication, loving-kindness, self-compassion, mindful listening, dealing with difficulties, the 3 step meditation, walking meditation, body scan with progressive relaxation, thoughts, emotions, gratitude, sounds and breathing” and home practice. The teachers were measured before and after training and 12 months later for quality of life, perceived stress, resilience, and positive and negative emotions. In addition, blood was drawn and assayed for cytokine levels, homocysteine, cysteine, and glutathione.

 

They found that in comparison to baseline and the lecture group, the group that received mindfulness training had significantly greater increases in physical, psychological, social, and environmental quality of life, resilience, positive emotions, cysteine, and glutathione and a significantly greater decrease in perceived stress, negative emotions, and the cytokines of IL-6 and IL-8.

 

These results suggest that mindfulness training improves teacher’s quality of life, and psychological well-being. Physically, it also reduced markers of inflammation and improved antioxidant systems. This suggests that mindfulness training makes teachers healthier and happier. Although not measures, this surely will help to reduce the likelihood of burnout and improve the quality of the teacher’s work in the classroom.

 

So, improve teachers’ physiological and psychological well-being with mindfulness.

 

“Teachers can use mindfulness as a resource to self-regulate emotions resulting from job stress, thereby increasing their ability to focus on the students and their performances in the classrooms.” – Kelsey Milne

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Twitter @MindfulResearch

 

Study Summary

 

Rodrigues de Oliveira, D., Wilson, D., Palace-Berl, F., de Mello Ponteciano, B., Fungaro Rissatti, L., Sardela de Miranda, F., Piassa Pollizi, V., Fuscella, J. C., Mourão Terzi, A., Lepique, A. P., D’Almeida, V., & Demarzo, M. (2021). Mindfulness meditation training effects on quality of life, immune function and glutathione metabolism in service healthy female teachers: A randomized pilot clinical trial. Brain, behavior, & immunity – health, 18, 100372. https://doi.org/10.1016/j.bbih.2021.100372

 

Abstract

Background

Despite the crucial role of educators in encourage students’ academic learning, addressing educator stress inside the classroom remains a significant challenge in the educational context. Mindfulness Meditation training (MM) has been recommended as an environmental enrichment strategy in schools to help teachers cope with stress and cultivating a state of awareness in daily life. Although studies have shown that MM can improve immune system dynamics the biological mechanism underlying glutathione metabolism in a healthy human is unclear

Objective

The purpose of this study was to determine whether MM training benefits psychological and behavioral response, immunological functions and glutathione metabolism in service healthy female teachers from public schools

Methods

We randomly assigned 76 teachers to an 8-week Mindfulness-Based Health Program for Educators (MBHPEduca) or Neuroscience for Education program (Neuro-Educa; active control group). Using the quality of life as our primary outcome, perceived stress, negative affectivity, and resilience as our secondary outcome, and pro-inflammatory cytokines and glutathione levels as our third outcome at baseline and post-intervention that occurred in public schools. Blood samples were collected for the measurement of three proinflammatory markers, including interleukin-1β (IL-1β), interleukin-6 (IL-6), and interleukin-8 (IL-8) and three GSH metabolism, including Cysteine (Cys), Homocysteine (HCys) and GSH were conducted at pre-and post-intervention, with selfreported assessments over time. Treatment effects were analyzed using generalized estimating equations (GEE) with to intention to treat

Results

We observed statistically significant improvements to the MBHP-Educa group compared to active control in perceived stress, resilience, positive and negative affect, and quality of life after 8-weeks MM (p ​< ​0.0001). Further, the MBHP-Educa group exhibited lower circulating IL-6 production accompanied by high circulating GSH, and Cys (p ​< ​0.0001). Additional analyses indicated that enhancing quality of life through mindfulness meditation training was mediated by reducing perceived stress and serum levels of IL- 6 and increasing resilience and teachers ‘plasma GSH levels

Conclusions

The present study is a pilot trial with low-power and provides preliminary evidence that mindfulness meditation training help teachers to cope with stress in the school environment with an impact on the quality of life, immune function, and glutathione metabolism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566766/

 

Improve the Psychological Well-Being of Parents of Children with Autism Spectrum Disorder with Mindfulness

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Improve the Psychological Well-Being of Parents of Children with Autism Spectrum Disorder with Mindfulness

 

By John M. de Castro, Ph.D.

 

“mindfulness instruction may help to ease the stress of parenting young children with autism.” – B. Grace Bullock

 

Providing care for children with autism spectrum disorder (ASD) can be particularly challenging. These children’s behavior is characterized, in varying degrees, by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviors. These make it difficult to relate to the child and receive the kind of positive feelings that often help to support caregiving. The challenges of caring for a child with ASD require that the parent be able to deal with stress, to regulate their own emotions, and to be sensitive and attentive to their child. These skills are exactly those that are developed in mindfulness training. It improves the psychological and physiological responses to stress. It improves emotion regulation. And it improves the ability to maintain attention and focus in the face of high levels of distraction.

 

A therapeutic technique that contains mindfulness training and Cognitive Behavioral Therapy (CBT) is Acceptance and Commitment Therapy (ACT). It focuses on the individual’s thoughts, feelings, and behavior and how they interact to impact their psychological and physical well-being. It then works to change thinking to alter the interaction and produce greater life satisfaction. ACT employs mindfulness practices to increase awareness and develop an attitude of acceptance and compassion in the presence of painful thoughts and feelings. ACT teaches individuals to “just notice”, accept and embrace private experiences and focus on behavioral responses that produce more desirable outcomes. It is not known whether ACT can improve the psychological well-being of parents of children with autism spectrum disorder. 

 

In today’s Research News article “The Effect of Acceptance and Commitment Therapy for Improving Psychological Well-Being in Parents of Individuals with Autism Spectrum Disorders: A Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892587/ ) Marino and colleagues recruited families with children between the ages of 4-10 and diagnosed with autism spectrum disorder and randomly assigned them to receive 24 weekly 90-minute sessions of either Acceptance and Commitment Therapy (ACT) or positive parent training to teach behavioral management skills to the children. The parents were measured before and after training for psychological flexibility, their emotions, the severity of disruptive and non-compliant behaviors in the children, behavior congruent with values, mindfulness, parental distress, parent-child dysfunction, and difficult child measures.

 

They found that in comparison to baseline and the positive parent training group, the group that received either Acceptance and Commitment Therapy (ACT) had significantly greater improvements in psychological flexibility, their emotions, the severity of disruptive and non-compliant behaviors in the children, behavior congruent with values, mindfulness, and parental distress.

 

The results are exciting particularly because of the strength of the research design. The control condition was an alternative therapy that met similarly over a similar period of time. This controls for most sources of research confounding which greatly improves the strength of the conclusions. These results suggest that Acceptance and Commitment Therapy (ACT) is a safe and effective treatment for parents of children with autism spectrum disorder improving the parent’s psychological well-being and also the children’s’ behavior.. One of the key differences between ACT and positive parent training is the training in mindfulness. This suggests that mindfulness may be the key training for the benefits to the parents.

 

So, improve the psychological well-being of parents of children with autism spectrum disorder with mindfulness.

 

“mindfulness means that parents are developing more compassion for themselves instead of feeling like it’s the end of the world when they do yell. Instead, they can mindfully reflect, repair if needed, and try again.” Katy Oberle

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Marino, F., Failla, C., Chilà, P., Minutoli, R., Puglisi, A., Arnao, A. A., Pignolo, L., Presti, G., Pergolizzi, F., Moderato, P., Tartarisco, G., Ruta, L., Vagni, D., Cerasa, A., & Pioggia, G. (2021). The Effect of Acceptance and Commitment Therapy for Improving Psychological Well-Being in Parents of Individuals with Autism Spectrum Disorders: A Randomized Controlled Trial. Brain sciences, 11(7), 880. https://doi.org/10.3390/brainsci11070880

 

Abstract

Background: Acceptance and Commitment Therapy (ACT) has been demonstrated as effective in improving psychological well-being in several clinical domains, but there is no evidence regarding the parents of children with Autism Spectrum Disorder (ASD). Methods: In this randomized controlled trial, we evaluated the efficacy of the ACT matrix behavioral protocol in comparison to the Parent Training (PT) program, measuring several primary and secondary outcomes prior to and following treatments. Twelve parents were randomly and equally assigned to two demographically matched groups wherein individuals underwent 24 weekly meetings of ACT protocol (experimental group) or conventional PT (control group). Results: Parents enrolled in the ACT protocol demonstrated significant improvement in psychological flexibility, awareness states, personal values in everyday life, and parental stress, whereas reduced scores were elicited in parents’ perceptions of their child’s disruptive behaviors. Conclusions: The results of this randomized controlled trial, if repeated with a large number of subjects, could open the way to include ACT protocols in daily practice to support the development of new parenting skills.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301771/

 

Improve Worker Well-Being in Spite of Work-Life Conflicts with Mindfulness

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Improve Worker Well-Being in Spite of Work-Life Conflicts with Mindfulness

 

By John M. de Castro, Ph.D.

 

“For many busy professionals, the phrase “work-life balance” can seem like an oxymoron. In today’s world of multi-tasking and 24/7 connectivity, work can seem omnipresent and overwhelming. How can you possibly maintain your competitive edge at work while also nurturing a healthy personal life? . . . Mindfulness can bring us back into balance by acting as a bridge between work and life.” – Dorsey Standish

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. Indeed, the work environment has even become an important part of our social lives, with friendships and leisure time activities often attached to the people we work with. But work-related stress is epidemic in the western workplace. Almost two thirds of workers reporting high levels of stress at work. This stress can result in impaired health and can result in burnout; producing fatigue, cynicism, and professional inefficacy. To help overcome unhappiness, stress, and burnout, mindfulness practices have been implemented in the workplace. These mindfulness practices have been shown to markedly reduce the physiological and psychological responses to stress.

 

One of the stresses produced by the modern work environments results from work conflicting with the rest of the workers’ lives harming their well-being and mental health. But there is little understanding regarding how these conflicts affect the worker and what practices might help to mitigate the effects of work-life conflicts. Mindfulness helps to prevent the harmful effects of conflicts. So, it may help to blunt the effects of work-life conflict on the individual’s well-being.

 

In today’s Research News article “When Work Conflicts With Personal Projects: The Association of Work-Life Conflict With Worker Wellbeing and the Mediating Role of Mindfulness.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.539582/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1771688_a0P58000000G0YfEAK_Psycho_20211111_arts_A ) Pacheco and colleagues recruited adult workers and had them complete a questionnaire measuring mindfulness, positive mental health, well-being in the workplace, personality, and work-life conflict, including time-based conflict and strain-based conflict..

 

They report that the higher the levels of mindfulness the higher the levels of positive mental health and well-being in the workplace and the lower the levels of time-based conflict and strain-based conflict. They also found that the higher the levels of both time-based conflict and strain-based conflict the lower the levels of positive mental health and well-being in the workplace.

 

Using linear structural modelling to assess the interrelationships between the variables they found that both time-based conflict and strain-based conflict were associated with lower well-being in the workplace directly and also indirectly by being associated with lower mindfulness which was associated with lower well-being in the workplace. They also found that both time-based conflict and strain-based conflict were associated with lower positive mental health only indirectly by being associated with lower mindfulness which was associated with lower positive mental health.

 

These findings are correlational. So, no conclusions regarding causation can be reached. But in previous controlled research mindfulness training has been shown to improve mental health and well-being. So, the relationships with mindfulness observed here are likely due to causal connections. The findings, then, suggest that the conflicts between work and life in general are factors in lowering workers’ mental health and well-being at work. The findings further suggest that mindfulness is an important intermediary where mindfulness is a promoter of positive mental health and well-being at work, but work-life conflicts reduce mindfulness. Future research should attempt to train mindfulness to observe whether it can mitigate the negative effects of work-life conflicts.

 

So, improve worker well-being in spite of work-life conflicts with mindfulness.

 

“[mindfulness] is effective for encouraging work–life balance and improve well-being.” – Sarah Elena Althammer

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Pacheco T, Coulombe S and Meunier S (2021) When Work Conflicts With Personal Projects: The Association of Work-Life Conflict With Worker Wellbeing and the Mediating Role of Mindfulness. Front. Psychol. 12:539582. doi: 10.3389/fpsyg.2021.539582

 

The negative emotional and health effects of work-life conflict (WLC) have been demonstrated in numerous studies regarding organizational psychology and occupational health. However, little is known about WLC’s relationship with positive wellbeing outcomes, including emotional, psychological, and social aspects of workers’ thriving. Furthermore, the mediating processes underlying the effects of WLC remain mostly unknown. The current study investigated the associations of perceived time- and strain-based WLC with positive mental health and thriving at work, as well as the mediating role of mindfulness in these associations. It is argued that WLC causes reduced mindfulness capacities among workers, which is in turn associated with lower positive wellbeing given the importance of mindfulness in emotion regulation. A sample of 330 workers based in Québec, Canada, completed an online survey including a measure of strain- and time-based interference with personal projects (i.e., the goals and activities that define the daily life of an individual) and validated scales of wellbeing outcomes and mindfulness. Results of structural equation modeling revealed negative associations between time- and strain-based WLC with positive mental health and thriving at work. Work-life conflict was related to lower mindfulness, which played a mediating role in the associations between time-based WLC with positive mental health and thriving at work, as well as strain-based WLC with positive mental health. The mediation was complete for the time-based WLC and positive mental health association, but partial for the other mediated pathways, highlighting the need for more research to identify additional mediators. These results highlight that beyond resulting in negative emotional/health outcomes often studied in previous research, WLC may be associated with workers’ reduced potential to live a fulfilling life, in general and in the workplace. Recommendations (e.g., mindfulness intervention to promote emotional regulation, personal project intervention) for workplace policymakers and practitioners are identified.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.539582/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1771688_a0P58000000G0YfEAK_Psycho_20211111_arts_A

 

Psychedelic Drug Experiences Produce Long-Term Improvements in Psychological Well-Being

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Psychedelic Drug Experiences Produce Long-Term Improvements in Psychological Well-Being

 

By John M. de Castro, Ph.D.

 

“Awe may be a critically important emotional experience during psychedelic treatment in generating compassion, empathy, and overall well-being” – Eve Ekman

 

Psychedelic substances such as peyote, mescaline, LSD, Bufotoxin, ayahuasca and psilocybin have been used almost since the beginning of recorded history to alter consciousness and produce spiritually meaningful experiences. People find these experiences extremely pleasant. eye opening, and even transformative. They often report that the experiences changed them forever. Psychedelics have also been found to be clinically useful as they markedly improve mood, increase energy and enthusiasm and greatly improve clinical depression. Even though the effects of psychedelic substances have been experienced and reported on for centuries, only very recently have these effects come under rigorous scientific scrutiny.

 

In today’s Research News article “Sustained, Multifaceted Improvements in Mental Well-Being Following Psychedelic Experiences in a Prospective Opportunity Sample.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277190/ ) Mans and colleagues recruited adults who were planning on having a psychedelic experience and had them complete a questionnaire before and after the experience and 2 weeks, 4 weeks, and 2 years after measuring well-being, depression, self-esteem, life orientation, emotional stability, meaning in life, acceptance, resilience, mindfulness, social connectedness, gratitude, spiritual transcendence, Spiritual and Religious Attitudes in Dealing with Illness, trust, and compassion and after the experience only Challenging Experience Questionnaire (CEQ), the Mystical Experience Questionnaire (MEQ), and the Emotional Breakthrough.

 

They found that in comparison to baseline after the psychedelic experiences there were significant improvements in all measures except spirituality that were maintained over follow-up. Factor analysis revealed three clusters of measures labelled as being well, staying well, and spirituality. They found that after the psychedelic experiences there were large significant improvements in being and staying well that were still present 2 years later.

 

It should be noted that there wasn’t a comparison, control, condition present and that the participants self-selected to engage in psychedelic experiences. Hence, a myriad of confounding alternative explanations for the findings abound, particularly participant expectancy effects (placebo effects). So, great caution must be exercised in drawing conclusions regarding the effects of psychedelic drugs. But placebo effects are generally transitory and don’t last over substantial periods of time and the present improvements lasted for at least 2 years, making it unlikely that confounding variable explanations are viable.

 

It is interesting that spirituality was not affected as psychedelic drugs have been employed throughout history as a part of spiritual development. It is possible that the context of spiritual ceremony is essential for the effects of psychedelic drugs being interpreted as spiritual effects.

 

The results of the present study suggest that people who engage in psychedelic experiences have profound improvements in their well-being that are sustained for at least 2 years. The magnitude and duration of the effects may explain why psychedelics have such profound effects on people with mental illnesses producing relief of symptoms and appear to be safe and effective treatments for mental illnesses.

 

So, psychedelic drug experiences produce long-term improvements in psychological well-being.

 

“use of psychedelic substances in a naturalistic setting is associated with experiences of personal transformation, a sense of altered moral values, increased feelings of social connectedness, and a more positive mood.” – Matthias Forstmann

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Mans, K., Kettner, H., Erritzoe, D., Haijen, E., Kaelen, M., & Carhart-Harris, R. L. (2021). Sustained, Multifaceted Improvements in Mental Well-Being Following Psychedelic Experiences in a Prospective Opportunity Sample. Frontiers in psychiatry, 12, 647909. https://doi.org/10.3389/fpsyt.2021.647909

 

Abstract

In the last 15 years, psychedelic substances, such as LSD and psilocybin, have regained legitimacy in clinical research. In the general population as well as across various psychiatric populations, mental well-being has been found to significantly improve after a psychedelic experience. Mental well-being has large socioeconomic relevance, but it is a complex, multifaceted construct. In this naturalistic observational study, a comprehensive approach was taken to assessing well-being before and after a taking a psychedelic compound to induce a “psychedelic experience.” Fourteen measures of well-being related constructs were included in order to examine the breadth and specificity of change in well-being. This change was then analysed to examine clusters of measures changing together. Survey data was collected from volunteers that intended to take a psychedelic. Four key time points were analysed: 1 week before and 2 weeks, 4 weeks, and 2 years after the experience (N = 654, N = 315, N = 212, and N = 64, respectively). Change on the included measures was found to cluster into three factors which we labelled: 1) “Being well”, 2) “Staying well,” and 3) “Spirituality.” Repeated Measures Multivariate Analysis of Variance revealed all but the spirituality factor to be improved in the weeks following the psychedelic experience. Additional Mixed model analyses revealed selective increases in Being Well and Staying Well (but not Spirituality) that remained statistically significant up to 2 years post-experience, albeit with high attrition rates. Post-hoc examination suggested that attrition was not due to differential acute experiences or mental-health changes in those who dropped out vs. those who did not. These findings suggest that psychedelics can have a broad, robust and sustained positive impact on mental well-being in those that have a prior intention to use a psychedelic compound. Public policy implications are discussed.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277190/