Reduce Fatigue and Depression in Patients with Multiple Sclerosis with Mindfulness

Reduce Fatigue and Depression in Patients with Multiple Sclerosis with Mindfulness

 

By John M. de Castro, Ph.D.

 

the pragmatic resiliency skills of mindfulness training may be beneficial in helping to mitigate unpleasant and unpredictable mental and physical symptoms that are associated with an MS diagnosis.” – Rachel M. Gilbertson

 

Multiple Sclerosis (MS) is a progressive demyelinating disease which attacks the coating on the neural axons which send messages throughout the body and nervous system. It affects about 2 million people worldwide and about 400,000 in the U.S. It is most commonly diagnosed in people between the ages of 20 and 50 years. Unfortunately, there is no cure for multiple sclerosis. There are a number of approved medications that are used to treat MS but are designed to lessen frequency of relapses and slow the progression of the disease, but they don’t address individual symptoms. But MS is not fatal with MS patients having about the same life expectancy as the general population. Hence, most MS sufferers have to live with the disease for many years. Mindfulness practices have been shown to improve the symptoms of multiple sclerosis.

 

In today’s Research News article “Mindfulness training during brief periods of hospitalization in multiple sclerosis (MS): beneficial alterations in fatigue and the mediating role of depression.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499486/ ) Sauder and colleagues recruited patients diagnosed with Multiple Sclerosis (MS) who also had symptoms of fatigue and depression during a brief (>5-day) hospital stay. During their hospital stay the patients were administered daily 45-minute mindfulness training based upon Mindfulness-Based Cognitive Therapy (MBCT). They were measured before and after the hospital stay for depression, fatigue, rumination, mindfulness, cognition, and attention.

 

They found that in comparison to baseline after training there were significant increases in mindfulness and distraction techniques to cope with a negative mood and significant decreases in depression, general fatigue, and physical fatigue. Further, they found that the greater the increases in mindfulness the greater the reductions in fatigue and depression. A mediation analysis revealed that mindfulness decreased fatigue indirectly by reducing depression that in turn reduced fatigue.

 

The study lacked a control, comparison, condition and as such caution must be exercised in interpreting the results. But mindfulness has been previously demonstrated in controlled studies to reduce fatigue and depression in a wide variety of people. So, the effects of mindfulness reported here were probably due to mindfulness causing the improvements. What is new here is that mindfulness reduces depression and in turn fatigue in patients with Multiple Sclerosis (MS). The patients also had a significant increase in the coping strategy of using distraction during negative mood states. This suggests that mindfulness training helps them to learn to distract themselves from depression and this may be the mechanism whereby mindfulness reduces depression.

 

Depression and fatigue greatly reduce the patients’ ability to conduct their lives, reducing their quality of life, So, improving depression and fatigue can be very beneficial to these patients. This suggests that mindfulness training should be recommended for patients with Multiple Sclerosis (MS).

 

So, reduce fatigue and depression in patients with multiple sclerosis with mindfulness.

 

Mindfulness practice appears to be a safe, drug-free approach to coping with stress and anxiety, which may in turn help reduce your MS symptoms.” – Amit Sood

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Sauder, T., Hansen, S., Bauswein, C., Müller, R., Jaruszowic, S., Keune, J., Schenk, T., Oschmann, P., & Keune, P. M. (2021). Mindfulness training during brief periods of hospitalization in multiple sclerosis (MS): beneficial alterations in fatigue and the mediating role of depression. BMC neurology, 21(1), 390. https://doi.org/10.1186/s12883-021-02390-7

 

Abstract

Objectives

Persons with MS (PwMS) are frequently affected by fatigue and depression. Mindfulness-based interventions may reduce these symptoms in PwMS and consequently their application has been extended to various settings. Only few efforts have been made to explore effects of short-term mindfulness training during brief periods of hospitalization. In the current study, the feasibility and potential effects of short-term mindfulness training on depression, fatigue, rumination and cognition were explored in PwMS in an acute-care hospital setting. Based on previous work, it was further examined whether the relation between trait mindfulness and fatigue prior to and following the intervention was mediated by depression and whether a mediation effect was also observable throughout the intervention.

Methods

A short-term mindfulness training protocol was developed, tailored to the requirements of the acute-care setting. Subsequently, 30 PwMS were recruited sequentially and received mindfulness training during the routine clinical process (median duration in hospital: eight days, number of sessions: four). Participants completed relevant self-report measures (depression, fatigue, rumination) and a neuropsychological assessment before and after training.

Results

Participants reported significantly increased trait mindfulness and decreased depression and fatigue following the intervention. Respective change scores were highly correlated so that increased trait mindfulness was associated with decreased symptoms. In the rumination domain, patients reported a tendency for an increased adaptive ability to engage in distractive behavior during arising negative mood. Other measures of trait rumination and cognition remained relatively stable. Results of the mediation analyses indicated that depression mediated the negative relationship between trait mindfulness and fatigue symptoms at pre and post assessments. With regards to the change scores, an association between mindfulness and cognitive fatigue ceased to be significant when depression was controlled, albeit in this case, the mediation effect did not reach significance.

Conclusion

Results of the current study indicate that short-term mindfulness training during brief periods of hospitalization may be beneficial for PwMS. They further complement previous work by identifying depression as a potential mediator of the antagonistic relationship between mindfulness and fatigue. Based on the current exploratory study, future trials are warranted to address this mechanism of mindfulness training in more detail.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499486/

 

Mindfulness Improves the Psychological Well-Being of Teachers in Non-Western Societies

Mindfulness Improves the Psychological Well-Being of Teachers in Non-Western Societies

 

By John M. de Castro, Ph.D.

 

Teachers who practice “mindfulness” are better able to reduce their own levels of stress and prevent burnout.” – Dee DiGioia

 

Stress is epidemic in the western workplace with almost two thirds of workers reporting high levels of stress at work. This often produces burnout; fatigue, cynicism, emotional exhaustion, and professional inefficacy. Teachers experience burnout at high rates. Roughly a half a million teachers out of a workforce of three million, leave the profession each year and the rate is almost double in poor schools compared to affluent schools. Indeed, nearly half of new teachers leave in their first five years.

 

Burnout frequently results from emotional exhaustion. This exhaustion not only affects the teachers personally, but also the students, as it produces a loss of enthusiasm, empathy, and compassion. Regardless of the reasons for burnout or its immediate presenting consequences, it is a threat to schools and their students. In fact, it is a threat to the entire educational systems as it contributes to the shortage of teachers. Hence, methods of reducing stress and improving teacher psychological health needs to be studied.

 

Mindfulness techniques are gaining increasing attention for the treatment of the symptoms of stress and burnout. They have been demonstrated to be helpful in reducing the psychological and physiological responses to stress and for treating and preventing burnout in a number of work environments including schools. But most of the research focuses on teachers in Western societies. There is a need to study if mindfulness is equally effective in Eastern societies.

 

In today’s Research News article “Effectiveness and Mechanisms of Mindfulness Training for School Teachers in Difficult Times: A Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443903/ ) Tsang and colleagues recruited elementary and secondary school teachers in Hong Kong and randomly assigned them to either a wait-list or to receive 8 weekly 90-minute sessions of mindfulness training along with home practice. The mindfulness training was based upon the Mindfulness-Based Stress Reduction (MBSR) and the Mindfulness-Based Cognitive Therapy (MBCT) programs. They were measured before and after training and two months later for mindfulness, general health, insomnia, stress, positive and negative emotions, life satisfaction, emotion regulation, and mindfulness in teaching.

 

They found that in comparison to baseline and the wait-list group, the teachers who had received mindfulness training had significantly higher levels of mindfulness, general health, positive emotions, life satisfaction, emotion regulation, and mindfulness in teaching and significantly lower levels of insomnia, stress, and negative emotions that were maintained at the 2-month follow-up measurement. In addition, a mediation analysis demonstrated that mindfulness was associated with well-being directly and indirectly via emotion regulation such that mindfulness was associated with increased emotion regulation that was in turn associated with increased well-being. Similarly, mindfulness was associated with mindfulness in teaching directly and indirectly via well-being such that mindfulness was associated with increased well-being that was in turn associated with increased mindfulness in teaching.

 

The present study had a passive control condition, wait-list, and this leaves a number of potential confounding explanations of the results such as placebo effects, attentional effects, and experimenter bias. But a large amount of previous controlled research has demonstrated that mindfulness training produces increases in health, positive emotions, emotion regulation, and life satisfaction, and decreases in insomnia, stress, and negative emotions. So, the present benefits are likely due to the mindfulness training.

 

The findings are important as they demonstrate that teachers in an Eastern society were benefited by mindfulness training to the same extent and in the same ways as teachers in Western societies. Thus, the effects of mindfulness training appear to be universal, regardless of culture. The findings also demonstrate that mindfulness training has direct and indirect effects on well-being that similarly effects mindfulness in teaching. All of this suggests that mindfulness training improves the psychological well-being of teachers which likely makes them happier and more effective teachers.

 

So, mindfulness improves the psychological well-being of teachers in non-western societies

 

Through yoga, mindfulness and social-emotional learning exercises, educators . . .  learned strategies to help reduce stress, prioritize self-care, cultivate resilience and enhance their well-being.” – Wendy McMahon

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Tsang, K., Shum, K. K., Chan, W., Li, S. X., Kwan, H. W., Su, M. R., Wong, B., & Lam, S. F. (2021). Effectiveness and Mechanisms of Mindfulness Training for School Teachers in Difficult Times: A Randomized Controlled Trial. Mindfulness, 1–12. Advance online publication. https://doi.org/10.1007/s12671-021-01750-1

 

Abstract

Objectives

Research in recent years has shown that mindfulness-based interventions can enhance teachers’ mental and physical health. However, the existing studies were predominantly conducted in Western, educated, industrialized, rich, and democratic (WEIRD) societies. As a randomized controlled trial in a non-WEIRD society, the present study examined the effectiveness and mechanisms of mindfulness training for Hong Kong teachers in difficult times.

Methods

Teachers from primary and secondary schools (n = 186) were randomly assigned to mindfulness training (eight-week .b Foundations) or waitlist control condition. They completed online self-report surveys on measures of well-being, emotion management, and mindfulness in teaching at baseline, post-intervention, and two-month follow-up.

Results

The intervention group reported significantly higher levels of life satisfaction, positive affect, general health, along with significantly lower levels of insomnia, stress, and negative affect than the control group at post-test and two-month follow-up. The effect sizes were medium to large (ηp2 = 0.06 to 0.14). More importantly, teachers’ baseline well-being had a significant moderating effect on the intervention effectiveness. Those with a lower baseline in well-being benefitted more than their counterparts with a higher baseline. In addition, teachers’ emotion management was found to be the mediator through which mindfulness training enhanced teachers’ well-being. Such improvement in well-being also predicted higher levels of mindfulness in teaching.

Conclusions

This study provides evidence on the efficacy of mindfulness training for teachers beyond WEIRD societies. It suggests the universality and practicality of mindfulness training in enhancing teachers’ well-being and reducing their distress in difficult times.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443903/

 

Improve Worker’s Psychological Wellbeing and Work Engagement and Performance with Mindfulness

Improve Worker’s Psychological Wellbeing and Work Engagement and Performance with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness impacts the individual holistically. This impact translates quickly into the workplace and appears as shifts in the approach to work, in changes in mindsets and in being present more, among others, opening the possibility for employees to impact the bottom line through these changes.” – Fabiola Fajardo

 

Work is very important for our health and well-being. We spend approximately 25% of our adult lives at work. How we spend that time is immensely important for our psychological, social, and physical health. But nearly 2/3 of employees worldwide are unhappy at work. This is partially due to work-related stress which is epidemic in the western workplace. Almost two thirds of workers report high levels of stress at work. This stress can result in impaired health and can result in burnout, producing fatigue, cynicism, and professional inefficacy.

 

To help overcome unhappiness, stress, and burnoutmindfulness practices have been implemented in the workplace. Indeed, mindfulness practices have been shown to markedly reduce the physiological and psychological responses to stress. As a result, it has become very trendy for business to incorporate meditation into the workday to help improve employee well-being, health, and productivity. These programs attempt to increase the employees’ mindfulness at work and thereby reduce stress.

 

In today’s Research News article “Differential Effects of Mindfulness-Based Intervention Programs at Work on Psychological Wellbeing and Work Engagement.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.715146/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1741394_a0P58000000G0YfEAK_Psycho_20210930_arts_A ) Calcagni and colleagues recruited “white collar” workers and randomly assigned them to receive either mindfulness training based upon the Mindfulness-Based Cognitive Therapy (MBCT) program or to a wait-list control condition. The mindfulness training occurred in either 6 weekly 2-hour sessions of 3 weekly 4-hour sessions along with daily home practice. They were measured before and 1-week after training for mindfulness, psychological well-being, work engagement, work performance, and perceived stress.

 

They found that in comparison to baseline and the wait-list control group, the mindfulness group had significantly lower levels of perceived stress and significantly higher levels of mindfulness, including the describe, acting with awareness, and no-reactivity subscales. They also had significantly higher levels of psychological well-being, including the positive relations, autonomy, and environmental mastery subscales. For work engagement they found significantly higher levels for the mindfulness group including the vigor and absorption subscales. Finally, after training the mindfulness group had significantly higher levels of work performance including the in-role and extra-role subscales.

 

It appears that mindfulness training of “white collar” workers produces improved psychological well-being, engagement with work and job performance. These results are similar to those observed in previous research in a wide variety of contexts and participants including improves well-being and work engagement and performance. So, mindfulness training is an effective method to improve the work and psychological health of “white collar” workers. These results suggest that mindfulness training would reduce the likelihood of burnout and improve retention of workers. This provides support for mindfulness training in work environments.

 

So, improve worker’s psychological wellbeing and work engagement and performance with mindfulness.

 

Mindfulness-based practices can improve workers’ health and reduce employers’ costs by ameliorating the negative effect of stress on workers’ health.” – Diana Kachan

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Calcagni CC, Salanova M, Llorens S, Bellosta-Batalla M, Martínez-Rubio D and Martínez Borrás R (2021) Differential Effects of Mindfulness-Based Intervention Programs at Work on Psychological Wellbeing and Work Engagement. Front. Psychol. 12:715146. doi: 10.3389/fpsyg.2021.715146

 

Two different mindfulness-based interventions were deployed in a sample of white-collar workers to explore the differential effects on different facets of mindfulness, dimensions of psychological wellbeing, work engagement, performance, and stress of a participant. A total of 28 participants completed one of the different programs, and their results were compared between groups and against 27 participants randomly allocated to a waiting list control group. Results suggest both mindfulness intervention programs were successful at increasing the levels of psychological wellbeing, work engagement, and performance of the participants, as well as decreasing their levels of stress. Significant differences were found between the two programs in all outcome variables. Results suggest that brief and customized mindfulness interventions at work are as successful as lengthier programs.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.715146/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1741394_a0P58000000G0YfEAK_Psycho_20210930_arts_A

 

Improve Well-Being of Healthy Individuals with Mindfulness

Improve Well-Being of Healthy Individuals with Mindfulness

 

By John M. de Castro, Ph.D.

 

“engaging in mindfulness meditation cultivates our ability to both focus and broaden our attention, which is a practical way to elicit psychological well-being.” – Jennifer Wolkin

 

The primary focus of the majority of research on mindfulness has been on its ability to treat mental illness and negative emotional states such as anxiety, depression, and perceived stress. As such, it has been found to be effective for a large array of medical and psychiatric conditions, either stand-alone or in combination with more traditional therapies. But mindfulness training has also been shown to improve health and well-being in healthy individuals.

 

The most commonly used mindfulness technique for the treatment of depression is Mindfulness-Based Cognitive Therapy (MBCT).  MBCT involves mindfulness training, containing sitting and walking meditation and body scan, and cognitive therapy to alter how the patient relates to the thought processes that often underlie and exacerbate psychological symptoms. MBCT was developed to treat mental illness. So, it is not known if it can improve the well-being of healthy individuals.

 

In today’s Research News article “Effectiveness of Mindfulness-Based Cognitive Therapy for Improving Subjective and Eudaimonic Well-Being in Healthy Individuals: A Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2021.700916/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1714167_a0P58000000G0YfEAK_Psycho_20210831_arts_A ) Kosugi and colleagues recruited healthy adults and randomly assigned them to either a wait-list control condition or to receive 8 weekly, 2-hour group sessions of Mindfulness-Based Cognitive Therapy (MBCT). They were measured before, during, and after training and 8 weeks later for satisfaction with life, flourishing, positive and negative experiences, self-esteem, mindfulness, self-compassion, resilience, anxiety, depression, perceived stress, presenteeism, interoceptive awareness, and quality of life.

 

They found that in comparison to baseline and the wait-list control group, the group that received Mindfulness-Based Cognitive Therapy (MBCT) had significant increases in satisfaction with life, interoceptive awareness, mindfulness, self-compassion, resilience, and work productivity that were maintained 8 weeks after the end of training. Hence, MBCT produced significant improvements in the psychological states of healthy adults. So, MBCT is not only effective in improving the mental health of individuals with mental problems but also can increase the positive psychological states in healthy individuals.

 

This study had a passive comparison (control) condition. This leaves open the possibility that the results were affected by participant expectancies (placebo), experimenter bias, or attentional (Hawthorne) effects. Future research should compare Mindfulness-Based Cognitive Therapy (MBCT) treatment to an active control condition, e.g. exercise to eliminate the possible confounding variables.

 

So, improve well-being of healthy individuals with mindfulness.

 

The practice of mindfulness is an effective means of enhancing and maintaining optimal mental health and overall well-being, and can be implemented in every aspect of daily living.” – Rezvan Ameli

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Kosugi T, Ninomiya A, Nagaoka M, Hashimoto Z, Sawada K, Park S, Fujisawa D, Mimura M and Sado M (2021) Effectiveness of Mindfulness-Based Cognitive Therapy for Improving Subjective and Eudaimonic Well-Being in Healthy Individuals: A Randomized Controlled Trial. Front. Psychol. 12:700916. doi: 10.3389/fpsyg.2021.700916

 

Objectives: Better subjective and eudaimonic well-being fosters better health conditions. Several studies have confirmed that mindfulness-based interventions are effective for improving well-being; however, the samples examined in these studies have been limited to specific populations, and the studies only measured certain aspects of well-being rather than the entire construct. Additionally, few studies have examined the effect of mindfulness-based cognitive therapy on well-being. The present study examines the feasibility of mindfulness-based cognitive therapy and its effectiveness for improving subjective and eudaimonic well-being among community residents.

Methods: The study design featured an 8-week randomized, waiting-list controlled, parallel-group study. 8 weekly mindfulness classes, followed by 2 monthly classes, were provided for healthy individuals aged 20–65 years who had a Satisfaction with Life Scale score of ≤ 24 indicating average to low cognitive aspect of subjective well-being. This trial was registered with the University Hospital Medical Information Network Clinical Trials Registry (ID: UMIN000031885, URL: https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000036376).

Results: The results showed that cognitive aspect of subjective well-being and mindfulness skills were significantly improved at 8 weeks, and this effect was enhanced up to the end of the follow-up period. Positive affective aspect of subjective and eudaimonic well-being were significantly improved at 16 weeks.

Conclusions: Eight weeks of mindfulness-based cognitive therapy with a 2-month follow-up period improves cognitive and affective aspects of subjective and eudaimonic well-being in healthy individuals. The order of improvement was cognitive, positive affective, and eudaimonic well-being. To verify these findings, multi-center randomized controlled trials with active control groups and longer follow-up periods are warranted.

https://www.frontiersin.org/articles/10.3389/fpsyg.2021.700916/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1714167_a0P58000000G0YfEAK_Psycho_20210831_arts_A

 

Relieve Insomnia in Older Adults with Tai Chi or Exercise

Relieve Insomnia in Older Adults with Tai Chi or Exercise

 

By John M. de Castro, Ph.D.

 

“Tai Chi significantly improved sleep quality in both healthy adults and patients with chronic health conditions, which suggests that Tai Chi may be considered as an alternative behavioral therapy in the treatment of insomnia.” – Gown Raman

 

Modern society has become more around-the-clock and more complex producing considerable pressure and stress on the individual. The advent of the internet and smart phones has exacerbated the problem. The resultant stress can impair sleep. Indeed, it is estimated that over half of Americans sleep too little due to stress. As a result, people today sleep 20% less than they did 100 years ago. Not having a good night’s sleep has adverse effects upon the individual’s health, well-being, and happiness. It has been estimated that 30 to 35% of adults have brief symptoms of insomnia, 15 to 20% have a short-term insomnia disorder, and 10% have chronic insomnia

 

Insomnia is more than just an irritant. Sleep deprivation is associated with decreased alertness and a consequent reduction in performance of even simple tasks, decreased quality of life, increased difficulties with memory and problem solving, increased likelihood of accidental injury including automobile accidents, and increased risk of dementia and Alzheimer’s disease. It also can lead to anxiety about sleep itself. This is stressful and can produce even more anxiety about being able to sleep. About 4% of Americans revert to sleeping pills. But these do not always produce high quality sleep and can have problematic side effects. So, there is a need to find better methods to treat insomnia. Mindfulness-based practices have been reported to improve sleep amount and quality and help with insomnia.

 

Tai Chi is an ancient mindfulness practice involving slow prescribed movements. It is gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. Indeed, studies have shown that Tai Chi practice is effective in improving sleep. But Tai Chi is both a mindfulness practice and an exercise. It is unclear whether its effects on insomnia are due to the exercise provided or the mindfulness practice.

 

In today’s Research News article “). Effects of Tai Chi or Exercise on Sleep in Older Adults With Insomnia: A Randomized Clinical Trial.” (See summary below or view the full text of the study at: ) Siu and colleagues recruited older sedentary adults over 60 years of age who were diagnosed with chronic insomnia and randomly assigned them to receive either treatment as usual, or 12 weeks of 3 weekly 1-hour sessions of  exercise, or Tai Chi practice. Exercise consisted of brisk walking and muscle strengthening. Tai Chi practice consisted of the 24 form Yang style Tai Chi. They were measured before and after treatment and 24 months later for objective sleep quality with actigraphy and subjectively for remission of insomnia, insomnia treatment response, perceived sleep quality, insomnia severity, self-reported sleep parameters, and the use of hypnotic medication.

 

They found that in comparison to baseline and the usual care group, the actigraphy and Tai Chi groups had significant improvements in objective sleep measures of sleep efficiency, sleep onset, wake time after sleep onset, and number of awakenings, and subjective measures of remission of insomnia, perceived sleep quality, insomnia severity, and lower use of hypnotic medications. Importantly, these improvements were still present 2 years later.

 

Hence, both objective and subjective measures of sleep revealed that both exercise and Tai Chi practice produced moderate significant and enduring improvements in sleep in older adults with insomnia. The fact that exercise and Tai Chi practice produced equivalent benefits suggests that the ability of Tai Chi practice to improve sleep is due to the exercise provided by the practice and not to the mindfulness aspects of the practice.

 

So, relieve insomnia in older adults with tai chi or exercise.

 

“TCC [Tai Chi Chih] produce clinically meaningful improvements in insomnia.” – Michael Irwin

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Siu, P. M., Yu, A. P., Tam, B. T., Chin, E. C., Yu, D. S., Chung, K. F., Hui, S. S., Woo, J., Fong, D. Y., Lee, P. H., Wei, G. X., & Irwin, M. R. (2021). Effects of Tai Chi or Exercise on Sleep in Older Adults With Insomnia: A Randomized Clinical Trial. JAMA network open, 4(2), e2037199. https://doi.org/10.1001/jamanetworkopen.2020.37199

 

Key Points

Question

Can tai chi improve sleep as effectively as conventional exercise in older adults with insomnia?

Findings

In this randomized clinical trial using data collected from 320 older adults, both tai chi and conventional exercise were associated with improved sleep. Both interventions were equally effective in improving various actigraphy-assessed sleep parameters, and these beneficial effects remained persistent 24 months after the intervention with no significant differences between the 2 intervention groups.

Meaning

Given that tai chi is an accepted form of physical activity among older people because of its gentle, low-impact exercises, it can represent an alternative approach to fulfill the physical activity recommendations for improving sleep for individuals who are averse to conventional exercise.

Abstract

Importance

Previous studies that have shown tai chi to improve sleep were mainly based on subjective assessments, which might have produced results confounded by self-reporting bias.

Objective

To compare the effectiveness of tai chi for improving sleep in older adults with insomnia with conventional exercise and a passive control group using actigraphy-based objective measurements.

Design, Setting, and Participants

This randomized, 3-arm, parallel group, assessor-masked clinical trial was conducted at a single research unit in Hong Kong between August 2014 and August 2018. Eligible participants, aged 60 years or older and with chronic insomnia, were randomly allocated into tai chi training, exercise, and control groups.

Interventions

12-week tai chi training, 12-week conventional exercise, and no intervention control.

Main Outcomes and Measures

Primary outcomes were measures taken from actigraphy sleep assessment. Secondary outcomes included remission of insomnia, insomnia treatment response, Pittsburgh Sleep Quality Index score, Insomnia Severity Index score, and self-reported sleep using a 7-day sleep diary. Assessments were performed at baseline, end of the intervention (postintervention), and 24 months after the intervention (follow-up). Data analysis was performed from September 2018 to August 2020.

Results

A total of 320 participants (mean [SD] age, 67.3 [6.8] years; mean [SD] insomnia duration, 124.4 [134.5] months; 256 [80.0%] women) were randomly allocated into control (110 participants), exercise (105 participants), and tai chi (105 participants) groups and included in the data analysis. Compared with the control group, the exercise and tai chi groups showed improved sleep efficiency (exercise vs control: adjusted mean difference, +3.5%; 95% CI, 1.8-5.2; P < .001; tai chi vs control: adjusted mean difference, +3.4%; 95% CI, 1.6-5.1; P < .001) and reductions of wake time after sleep onset (exercise vs control: −17.0 minutes; 95% CI, −24.9 to −9.0; P < .001; tai chi vs control: −13.3 minutes; 95% CI, −21.3 to −5.2; P = .001) and number of awakenings (exercise vs control: −2.8 times; 95% CI, −4.0 to −1.6; P < .001; tai chi vs control: −2.2 times; 95% CI, −3.5 to −1.0; P < .001) as assessed by actigraphy at postintervention; although there were no significant differences between the exercise and tai chi groups. The actigraphy-assessed beneficial effects were maintained in both intervention groups at follow-up.

Conclusions and Relevance

Conventional exercise and tai chi improved sleep and the beneficial effects sustained for 24 months, although the absolute improvements in sleep parameters were modest. Improvements in objective sleep parameters were not different between the tai chi and exercise groups, suggesting that tai chi can be an alternative approach for managing insomnia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885034/

 

Reduce Stigma and Perceived Devaluation in Patients with Schizophrenia with Mindfulness

Reduce Stigma and Perceived Devaluation in Patients with Schizophrenia with Mindfulness

 

By John M. de Castro, Ph.D.

 

Stigma is the number one reason people do not seek help; therefore, efforts to reduce stigma are crucial to increasing people’s help-seeking behaviors.” – Sami Boomgarden

 

Stigma is a view that a distinguishing characteristic makes the individual less acceptable to others. This can lead to discrimination where stigmatized people are treated negatively either directly with ugly remarks such as “crazy” or “weird” or indirectly by being avoided or marginalized by others. This can produce fewer work opportunities, harassment, bullying, problems with insurance, and loneliness. The social isolation can even lead to early mortality. Stigma can lead to low self-esteem and self-stigmatization in which the individual adopts those negative stereotypes and as a result there is a loss of self-efficacy This leads to the individual ceasing trying to make things better, thinking “why try?”

 

Mindfulness promotes non-judgmental awareness in which the individual perceives things just as they are without labelling or making value judgements about them. It also promotes the ability to adaptively cope with emotions and reduces worry and rumination. These can be useful in overcoming stigmas and their effects, especially self-stigmas. So, mindfulness may buffer the individual from the effects of stigma and self-stigmatization in severe mental illnesses such as schizophrenia. Mindfulness-Based Cognitive Therapy (MBCT) involves the combination of mindfulness training and cognitive behavioral therapy. It contains sitting, walking and body scan meditations, and cognitive therapy that is designed to alter how the patient relates to the thought processes that often underlie and exacerbate psychological symptoms. Hence, MBCT may be particularly effective in reducing stigma in patients diagnosed with schizophrenia.

 

In today’s Research News article “Effects of Mindfulness-Based Cognitive Therapy on Stigma in Female Patients With Schizophrenia.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342917/ ) Tang and colleagues recruited patients diagnosed with schizophrenia and randomly assigned them to either receive 8 weeks of Mindfulness-Based Cognitive Therapy (MBCT) or to a treatment as usual control condition. They were measured before and after treatment for mindfulness, insight and treatment attitudes, and stigma including subscales measuring perceived devaluation-discrimination, stigma-coping orientation, and stigma-related feeling.

 

They found that in comparison to baseline and the control group, the participants who received Mindfulness-Based Cognitive Therapy (MBCT) had significantly higher levels of mindfulness and insight and treatment attitudes, and significantly lower levels of stigma, including perceived devaluation-discrimination and stigma-coping orientation. They also found that the higher the levels of mindfulness after treatment the lower the levels of stigma and the higher the levels of insight and treatment attitudes.

 

Stigma involves “shame, evaluative thoughts, and fear of enacted stigma that results from individuals’ identification with a stigmatized group”. Stigma is an impediment to successful treatment of mental illnesses and improvement of social function. In fact, many patients high in stigma refuse treatment all together. The findings of the present study suggest that mindfulness training can help patients diagnosed with schizophrenia overcome stigma and as a result improve their attitudes toward treatment. As a result, mindfulness training may improve the patient’s prognosis and make successful treatment more likely.

 

So, reduce stigma and perceived devaluation in patients with schizophrenia with mindfulness.

 

mindfulness-based psychoeducation was effective in reducing stigma in patients with schizophrenia.” – Emine Yılmaz

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Tang, Q., Yang, S., Liu, C., Li, L., Chen, X., Wu, F., & Huang, X. (2021). Effects of Mindfulness-Based Cognitive Therapy on Stigma in Female Patients With Schizophrenia. Frontiers in psychiatry, 12, 694575. https://doi.org/10.3389/fpsyt.2021.694575

 

Abstract

Mindfulness-based cognitive therapy (MBCT) has been increasingly recognized as effective in different mental illnesses, but these effects are limited in schizophrenia. For patients with schizophrenia, stigma is one of the most negative factors that affects treatment, rehabilitation and social function. This research aimed to determine the effects of MBCT on stigma in patients with schizophrenia. In total, 62 inpatients with schizophrenia were recruited and randomly assigned to the experimental group or control group. The experimental group received an 8-week MBCT intervention, and the control group were treated as usual. Link’s Stigma Scales (with three subscales, including perceived devaluation-discrimination (PDD), stigma-coping orientation, and stigma-related feeling), Five Facet Mindfulness Questionnaire (FFMQ), and Insight and Treatment Attitudes Questionnaire (ITAQ) were used to collect data before and after intervention. After intervention, the post-test score of PDD, stigma-coping orientation, FFMQ, and ITAQ were significantly different between the experimental group and the control group. In the experimental group, the PDD and stigma-coping orientation scores significantly decreased, and FFMQ and ITAQ scores increased remarkably (P < 0.05). In addition, correlation analysis revealed a significant negative correlation between mindfulness and stigma. MBCT was effective in reducing stigma in patients with schizophrenia, which mainly manifested as changes in the patients’ perception of stigma as well as the withdrawal and avoidance caused by schizophrenia. Enhancing mindfulness will help reduce the stigma level. MBCT is worthy of promotion and application in patients with schizophrenia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342917/

 

Improve Unmedicated Obsessive-Compulsive Disorder with Mindfulness

 

Improve Unmedicated Obsessive-Compulsive Disorder with Mindfulness

 

By John M. de Castro, Ph.D.

 

“a growing pool of research coming out over the last few years suggests that those who are adding mindfulness into treatment for OCD are on the right track.” – John Hershfield

 

Obsessive-Compulsive Disorder (OCD) sufferers have repetitive anxiety producing intrusive thoughts (obsessions) that result in repetitive behaviors to reduce the anxiety (compulsions). In a typical example of OCD, the individual is concerned about germs and is unable to control the anxiety that these thoughts produce. Their solution is to engage in ritualized behaviors, such as repetitive cleaning or hand washing that for a short time relieves the anxiety. The obsessions and compulsions can become so frequent that they become a dominant theme in their lives. Hence OCD drastically reduces the quality of life and happiness of the sufferer and those around them. About 2% of the population, 3.3 million people in the U.S., are affected at some time in their life.

 

Fortunately, Obsessive-Compulsive Disorder (OCD) can be treated, and many respond to Cognitive Behavioral Therapy (CBT). But some do not. Mindfulness training has been shown to be effective in treating OCDMindfulness-Based Cognitive Therapy (MBCT) involves the combination of mindfulness training and cognitive behavioral therapy. It contains sitting, walking and body scan meditations, and cognitive therapy that is designed to alter how the patient relates to the thought processes that often underlie and exacerbate psychological symptoms. MBCT has been shown to reduce anxiety. So, it makes sense to examine the effectiveness of MBCT for Obsessive-Compulsive Disorder (OCD).

 

In today’s Research News article “Mindfulness-Based Cognitive Therapy for Unmedicated Obsessive-Compulsive Disorder: A Randomized Controlled Trial With 6-Month Follow-Up.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369060/ ) Zhang and colleagues recruited adults diagnosed with Obsessive-Compulsive Disorder (OCD) and randomly assigned them to receive either drugs (SSRIs), or 10 weekly 150-minute sessions of Mindfulness-Based Cognitive Therapy (MBCT) or an active placebo control treatment, containing education about OCD, group support, and relapse prevention. They were measured before and after treatment and 6 months later for mindfulness, anxiety, depression, social function, and Obsessive-Compulsion severity.

 

They found that in comparison to baseline and the active placebo control group, both the drugs (SSRIs) and Mindfulness-Based Cognitive Therapy (MBCT) groups had significant improvements in Obsessive-Compulsion severity. But the differences were no longer significant at the 6-month follow-up where all groups were significantly improved. All groups had significant improvements in anxiety and depression that were maintained at the 6-month follow up.

 

These are interesting results that show that drugs (SSRIs) and Mindfulness-Based Cognitive Therapy (MBCT)  improve OCD severity after treatment to a greater extent than the placebo group. But 6 months after treatment all groups had equivalent significant improvements on OCD and all groups had significant reductions in anxiety and depression at all post-treatment time points. In other words, drugs, MBCT, and placebo are all effective in improving the symptoms of OCD patients. But drugs and MBCT are slightly more effective immediately after treatment. This suggests that regardless of the actual treatment, OCD is improved if the patients believe that the treatment will improve their symptoms.

 

So, improve unmedicated obsessive-compulsive disorder with mindfulness

 

Mindfulness requires you to be aware of intrusive thoughts or triggers, accept and possibly internally analyze any discomforts caused by such thoughts and resist the urge to respond with compulsions.” – NOCD

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Zhang, T., Lu, L., Didonna, F., Wang, Z., Zhang, H., & Fan, Q. (2021). Mindfulness-Based Cognitive Therapy for Unmedicated Obsessive-Compulsive Disorder: A Randomized Controlled Trial With 6-Month Follow-Up. Frontiers in psychiatry, 12, 661807. https://doi.org/10.3389/fpsyt.2021.661807

 

Abstract

Background: This was the first randomized controlled trial (RCT) designed to compare the efficacy of mindfulness-based cognitive therapy (MBCT) on unmedicated obsessive-compulsive disorder with that of the first-line treatment for OCD (SSRIs) or a placebo, as well as to analyze the treatment acceptability and safety of MBCT.

Methods: A total of 123 unmedicated OCD patients with mild to moderate symptoms were randomly assigned into selective serotonin reuptake inhibitors group (SSRIs group), MBCT group or psycho-education group (PE group), respectively. They were intervened for 10 weeks. The Yale–Brown Obsessive-Compulsive Scale (Y-BOCS) grade was the primary outcome, and Hamilton Depression Scale-24 (HAMD-24) and Hamilton Anxiety Scale (HAMA) grades were secondary outcomes to be measured at baseline, mid-intervention, post-intervention and 14, 22, and 34 weeks of follow-up. The Five Facet Mindfulness Questionnaire (FFMQ) and Sheehan Disability Scale (SDS) were used to assess mindfulness and social functions, respectively. In addition, treatment acceptability (dropout rate and frequency of occurrence) and safety [adverse event (AE)] of MBCT were investigated.

Results: Significant differences were detected in the treatment responses among SSRIs group, MBCT group and PE group. Notably, treatment responses were significantly better in the former two groups than that of PE group (χ2 = 6.448, p = 0.04), although we did not identify significant differences between SSRIs group and MBCT group (χ2 = 1.220, p = 0.543). Observed until 6 months of follow-up, there were no significant differences in treatment response among three groups. No AE was recorded in MBCT group.

Conclusion: MBCT is effective in the treatment of unmedicated OCD with mild to moderate symptoms comparable to that of SSRIs, which contributes to maintain the treatment outcomes at follow-up. Besides, MBCT is safe with a good clinical compliance.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369060/

 

Effectively Treat Substance Use Disorder with Mindfulness

Effectively Treat Substance Use Disorder with Mindfulness

 

By John M. de Castro, Ph.D.

 

“mindfulness is likely an effective tool in helping people with addiction because it’s a single, simple skill that a person can practice multiple times throughout their day, every day, regardless of the life challenges that arise.” – James Davis

 

Substance abuse is a major health and social problem. There are estimated 22.2 million people in the U.S. with substance dependence. It is estimated that worldwide there are nearly ¼ million deaths yearly as a result of illicit drug use which includes unintentional overdoses, suicides, HIV and AIDS, and trauma. Obviously, there is a need to find effective methods to prevent and treat substance abuse. There are a number of programs that are successful at stopping the drug abuse, including the classic 12-step program emblematic of Alcoholics Anonymous. Unfortunately, the majority of drug and/or alcohol abusers relapse and return to substance abuse.

 

Hence, it is important to find an effective method to treat substance abuse and prevent relapse but an effective treatment has been elusive. Most programs and therapies to treat addictions have poor success rates. Recently, mindfulness training has been found to be effective in treating addictions. The research has been accumulating. So, it makes sense to pause and take a look at what has been learned.

 

In today’s Research News article “A Narrative Review of Third-Wave Cognitive-Behavioral Therapies in Addiction.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080172/ ) Balandeh and colleagues review and summarize the published research studies of the effectiveness of mindfulness-based therapies for the treatment of addictions.

 

They report that the published research demonstrates that the mindfulness-based therapies of Mindfulness-Based Relapse Prevention (MBRP), Acceptance and Commitment Therapy (ACT), Dialectical Behavior Therapy (DBT), Mindfulness-Based Stress Reduction (MBSR), and Mindfulness-Based Cognitive Therapy (MBCT) are all effective for the treatment of addictions. These therapies vary greatly in emphasis and techniques. The major common thread is mindfulness training. This would suggest that it’s developing mindfulness per se that is effective in treating addictions.

 

They report that on a number of explanations for the effectiveness of mindfulness-based therapies for the treatment of addictions. These include the ability of mindfulness training to change the individual’s responses to the usual triggers for drug use, changing the brain’s response to cravings, and sensing cravings as just another physical sensation. Regardless of the mechanism or mechanisms, it is clear that mindfulness training is effective for the treatment of substance use disorder.

 

So, effectively treat substance use disorder with mindfulness.

 

One reason addiction is so hard to beat is that it’s a pattern of conditioned responses. The part of your brain responsible for higher reasoning essentially gets cut out of the decision-making process and you react reflexively to stimuli associated with drugs and alcohol. Practicing mindfulness gradually undoes this conditioning.” – Renewal Lodge

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Balandeh, E., Omidi, A., & Ghaderi, A. (2021). A Narrative Review of Third-Wave Cognitive-Behavioral Therapies in Addiction. Addiction & health, 13(1), 52–65. https://doi.org/10.22122/ahj.v13i1.298

 

Abstract

Substance use disorder (SUD) is a prevalent health issue with serious social and personal consequences. SUDs are linked to numerous physical health problems. In the Diagnostic and Statistical Manual of Mental Disorders-5th Edition (DSM-V), the essential characteristic of a SUD is a collection of cognitive, behavioral, and psychological manifestations indicative of the subject’s unbaiting substance use despite experiencing significant problems due to continued use. Several alternative interventions have been indicated. Among them, mindfulness-based therapies are receiving growing attention. This article reviews evidence for the use of third-wave cognitive-behavioral therapies (CBTs) in addiction treatment. We have reviewed the literature published from 1990 to 2019. Further research is required to better understand the types of mindfulness-based interventions that work best for specific types of addiction, patients, and situations. Current findings increasingly support third-wave CBTs as a promising complementary therapy for the treatment and prevention of addiction.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080172/

 

Improve the Psychological Well-Being of University Students with Mindfulness

Improve the Psychological Well-Being of University Students with Mindfulness

 

By John M. de Castro, Ph.D.

 

Mindfulness apps offer modest but clear benefits to users in terms of improved mental health. They present a promising supplement to traditional mental health services.” – Oskari Lahtinen

 

There is a lot of pressure on university students to excel so that they can get the best jobs after graduation. This stress might in fact be counterproductive as the increased pressure can actually lead to stress and anxiety which can impede the student’s physical and mental health, well-being, and school performance. Mindfulness training has been shown through extensive research to be effective in improving physical and psychological health. Indeed, these practices have been found to improve psychological health in college students.

 

In today’s Research News article “The Mental Health and Wellbeing of University Students: Acceptability, Effectiveness, and Mechanisms of a Mindfulness-Based Course.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199969/ ) Medlicott and colleagues recruited university students who attended an 8-week mindfulness training. The program was based upon Mindfulness-Based Cognitive Therapy (MBCT) and was delivered in 8 weekly 90 minute sessions along with daily home practice. The participants were measured before and after the program and 6 weeks later for expected benefits from the program, wellbeing, mental health, mindfulness, self-compassion, resilience, and academic goals.

 

They found that following the course there were significant improvement in wellbeing. mental health, mindfulness, self-compassion, resilience, and orientation toward their academic goals that were maintained 6 weeks later. The effects were greater for participants who had mental health problems at the beginning of the program. In addition, the greater the amount of home practice, the greater the improvements observed. The amount of change in mindfulness and self-compassion produced by the course was related to the amount of improvement in wellbeing and mental health while the amount of change in resilience was related to the improvements in wellbeing.

 

It has to be recognized that the study did not contain a control, comparison, condition, so it is open to numerous alternative, confounding, explanations. But previous controlled research has demonstrated that mindfulness training produces improvements in wellbeing, mental health, mindfulness, self-compassion, and resilience. So, it is likely that the present findings are the result of the effects of the mindfulness training program rather than some alternative explanation.

 

These results suggest that participating in a mindfulness training program produces significant benefits for the psychological health and wellbeing of university students. The fact their orientation to academic goals was also improved suggests that the program may also improve their academic performance. Indeed, it would be expected that improvement in the students wellbeing and mental health would improve the likelihood of academic success.

 

So, improve the psychological well-being of university students with mindfulness.

 

In college, it’s easy to compile all of the problems we’re facing and place it in to one big feeling of paranoia or stress. Headspace helps sort that out and filter what I should be worried about.” – Ryan Coughlin

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Medlicott, E., Phillips, A., Crane, C., Hinze, V., Taylor, L., Tickell, A., Montero-Marin, J., & Kuyken, W. (2021). The Mental Health and Wellbeing of University Students: Acceptability, Effectiveness, and Mechanisms of a Mindfulness-Based Course. International journal of environmental research and public health, 18(11), 6023. https://doi.org/10.3390/ijerph18116023

 

Abstract

Mental health problems are relatively common during university and adversely affect academic outcomes. Evidence suggests that mindfulness can support the mental health and wellbeing of university students. We explored the acceptability and effectiveness of an 8-week instructor-led mindfulness-based course (“Mindfulness: Finding Peace in a Frantic World”; Williams and Penman, 2011) on improving wellbeing and mental health (self-reported distress), orientation and motivation towards academic goals, and the mechanisms driving these changes. Eighty-six undergraduate and post-graduate students (>18 years) participated. Students engaged well with the course, with 36 (48.0%) completing the whole programme, 52 (69.3%) attending 7 out of 8 sessions, and 71 (94.7%) completing at least half. Significant improvements in wellbeing and mental health were found post-intervention and at 6-week follow-up. Improvements in wellbeing were mediated by mindfulness, self-compassion, and resilience. Improvements in mental health were mediated by improvements in mindfulness and resilience but not self-compassion. Significant improvements in students’ orientation to their academic goal, measured by “commitment” to, “likelihood” of achieving, and feeling more equipped with the “skills and resources” needed, were found at post-intervention and at 6-week follow-up. Whilst exploratory, the results suggest that this mindfulness intervention is acceptable and effective for university students and can support academic study.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199969/

 

Improve Brain Processing in Mood Dysregulated Adolescents with Mindfulness

Improve Brain Processing in Mood Dysregulated Adolescents with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Mindfulness-based interventions—practices that promote non-judgmental attention to the present—can help individuals respond with acceptance to challenging circumstances or emotions and is a promising approach to treatment of mood lability.” – D. M. Hafemann

 

Adolescence is a time of mental, physical, social, and emotional growth. But it can be a difficult time, fraught with challenges. During this time the child transitions to young adulthood; including the development of intellectual, psychological, physical, and social abilities and characteristics. There are so many changes occurring during this time that the child can feel overwhelmed and unable to cope with all that is required. This can lead to emotional and behavioral problems. Indeed, up to a quarter of adolescents suffer from depression or anxiety disorders, and an even larger proportion struggle with subclinical symptoms. Mindfulness training has been shown to improve emotion regulation and to benefit the psychological and emotional health of adolescents

 

The nervous system is a dynamic entity, constantly changing and adapting to the environment. It will change size, activity, and connectivity in response to experience. These changes in the brain are called neuroplasticity. Over the last decade neuroscience has been studying the effects of contemplative practices on the brain and has identified neuroplastic changes in widespread areas. In other words, mindfulness practice appears to mold and change the brain, producing psychological, physical, and spiritual benefits. The brains of adolescents are different from fully mature adult brains. They are dynamically growing and changing. It is unclear how mindfulness affects their maturing brains particularly in adolescents who have mood dysregulations.

 

In today’s Research News article “Network-level functional topological changes after mindfulness-based cognitive therapy in mood dysregulated adolescents at familial risk for bipolar disorder: a pilot study.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080341/ ) Qin and colleagues recruited adolescents (13-17 years of age) who were mood dysregulated and who had at least one biological parent with bipolar disorder. They were provided a once a week for 75 minutes for 12-weeks program of Mindfulness-Based Cognitive Therapy (MBCT) adapted for children along with home practice. They were measured before and after training for emotion regulation, depressive and manic symptoms, overall global functioning, and clinical ratings. They also had their brains scanned with functional Magnetic Resonance Imaging (fMRI).

 

In comparison to baseline they found that after Mindfulness-Based Cognitive Therapy (MBCT) there were surprisingly no significant changes in emotion regulation, depressive and manic symptoms, overall global functioning, and clinical ratings. But there were significant increases in network efficiency and decreases in path length in the cingulo-opercular network and frontal parietal network and increases in the connectivity of brain structures within the cingulo-opercular network and the default mode network. In addition, the shorter the path length within the cingulo-opercular network the higher the level of emotion regulation.

 

These results need to be interpreted with caution as there was no control comparison condition and so there are potential confounding variables that could account for the results. But the psychological results are very disappointing. Mindfulness-Based Cognitive Therapy (MBCT) has been routinely found to improve emotions and emotion regulation in previous research. But it did not in the present study. It is possible that unlike with adults, MBCT is simply ineffective in improving the psychological health of mood dysregulated adolescents.

 

On the other hand, the functional Magnetic Resonance Imaging (fMRI) findings were interesting. The cingulo-opercular network and frontal parietal network are both involved in top-down cognitive control. The observed increases in network efficiency within these networks after Mindfulness-Based Cognitive Therapy (MBCT) suggests that MBCT improves the ability of mood dysregulated adolescents to control their thinking. This is exactly what MBCT is designed to do. Unfortunately, the researchers did not measure cognitive ability in this study, so there is no confirmatory behavioral results. The increased emotion regulation associated with decreases in path length in the cingulo-opercular network, though, suggests that the changes in the youths’ brains may be associated with improved ability to control their emotions. This may suggest an a lessened chance of developing major mental illness in the future.

 

So, Improve Brain Processing in Mood Dysregulated Adolescents with Mindfulness.

 

With low level of mindfulness, adolescents might be lack of emotion clarity, self-control and acceptance, which in turn might lead to their poor realization of emotion and easy immersion into dysfunctional emotional reactions such as impulse and aggressive behavior toward others or blame to themselves.” – Ying Ma

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Qin, K., Lei, D., Yang, J., Li, W., Tallman, M. J., Duran, L., Blom, T. J., Bruns, K. M., Cotton, S., Sweeney, J. A., Gong, Q., & DelBello, M. P. (2021). Network-level functional topological changes after mindfulness-based cognitive therapy in mood dysregulated adolescents at familial risk for bipolar disorder: a pilot study. BMC psychiatry, 21(1), 213. https://doi.org/10.1186/s12888-021-03211-4

 

Abstract

Background

Given that psychopharmacological approaches routinely used to treat mood-related problems may result in adverse outcomes in mood dysregulated adolescents at familial risk for bipolar disorder (BD), Mindfulness-Based Cognitive Therapy for Children (MBCT-C) provides an alternative effective and safe option. However, little is known about the brain mechanisms of beneficial outcomes from this intervention. Herein, we aimed to investigate the network-level neurofunctional effects of MBCT-C in mood dysregulated adolescents.

Methods

Ten mood dysregulated adolescents at familial risk for BD underwent a 12-week MBCT-C intervention. Resting-state functional magnetic resonance imaging (fMRI) was performed prior to and following MBCT-C. Topological metrics of three intrinsic functional networks (default mode network (DMN), fronto-parietal network (FPN) and cingulo-opercular network (CON)) were investigated respectively using graph theory analysis.

Results

Following MBCT-C, mood dysregulated adolescents showed increased global efficiency and decreased characteristic path length within both CON and FPN. Enhanced functional connectivity strength of frontal and limbic areas were identified within the DMN and CON. Moreover, change in characteristic path length within the CON was suggested to be significantly related to change in the Emotion Regulation Checklist score.

Conclusions

12-week MBCT-C treatment in mood dysregulated adolescents at familial risk for BD yield network-level neurofunctional effects within the FPN and CON, suggesting enhanced functional integration of the dual-network. Decreased characteristic path length of the CON may be associated with the improvement of emotion regulation following mindfulness training. However, current findings derived from small sample size should be interpreted with caution. Future randomized controlled trials including larger samples are critical to validate our findings.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080341/