Psychedelic Use and Meditation Complement Each Other’s Impacts

Does the combination of psychedelics and meditation enhance mystical  experiences?

By John M. de Castro, Ph.D.

 

In today’s Research News article “Associations between psychedelic-related and meditation-related variables: A longitudinal study” (See summary below or view the full text of the study at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11999004/ )  Simonsson and colleagues examined the relationships between meditation and psychedelic use. They found that psychedelic use was associated with mindfulness and loving-kindness or compassion meditation practice while mindfulness was associated with less severe challenging psychedelic experiences, fewer psychedelic-occasioned thoughts or attempts of self- or other-harm.

 

Meditation and psychedelic use complement the impact of each.

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on the Contemplative Studies Blog  http://contemplative-studies.org

 

Study Summary

 

Simonsson O, Chaturvedi S, Hendricks PS, et al. Associations between psychedelic-related and meditation-related variables: A longitudinal study. J Psychiatr Res. 2025;184:457-463. doi:10.1016/j.jpsychires.2025.03.025

 

Abstract

Previous research has investigated associations between psychedelic experiences and meditation practice, but knowledge gaps remain. Using a longitudinal research design with a sample of US residents between 18 and 50 years old (N = 13,012), we investigated associations between psychedelic-related and meditation-related variables. The follow-up survey was completed by 7484 respondents, of whom 336 reported psychedelic use during the two-month study. In covariate-adjusted regression models, psychedelic use was associated with greater increases in the number of days of mindfulness and loving-kindness or compassion meditation practice in the past week, especially among those with no prior experience of psychedelics or meditation. Among those who reported psychedelic use, trait mindfulness and trait self-compassion at baseline were associated with less severe challenging psychedelic experiences, as well as lower odds of psychedelic-occasioned thoughts or attempts of self- or other-harm. However, among those who practiced meditation at baseline, psychedelic use was associated with greater increases in past-week frequency of loving-kindness or compassion meditation-related difficulties and impairments. Future research is warranted.

 

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