Month: September 2022

Reduce Dysfunctional Eating with Mindfulness

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Reduce Dysfunctional Eating with Mindfulness

 

By John M. de Castro, Ph.D.

 

“The more you eat, the less flavor; the less you eat, the more flavor.” ~Chinese Proverb

 

Around 30 million people in the United States of all ages and genders suffer from an eating disorder: either anorexia nervosa, bulimia, or binge eating disorder. 95% of those who have eating disorders are between the ages of 12 and 26. Eating disorders are not just troubling psychological problems, they can be deadly, having the highest mortality rate of any mental illness. Two example of eating disorders are binge eating disorder (BED) and bulimia nervosa (BN). BED involves eating a large amount of food within a short time-period while experiencing a sense of loss of control over eating. BN involves binge-eating and purging (e.g., self-induced vomiting, compensatory exercise).

 

Eating disorders can be difficult to treat because eating is necessary and cannot be simply stopped as in smoking cessation or abstaining from drugs or alcohol. One must learn to eat appropriately not stop. So, it is important to find methods that can help prevent and treat eating disorders. Contemplative practices, mindfulness, and mindful eating have shown promise for treating eating disorders. It is not known however, if mindfulness training can improve dysregulated eating and in turn reduce the likelihood of eating disorders.

 

In today’s Research News article “Delivering Mindfulness-Based Interventions for Insomnia, Pain, and Dysfunctional Eating Through a Text Messaging App: Three Randomized Controlled Trials Investigating the Effectiveness and Mediating Mechanisms.” (See summary below or view the full text of the study at:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115660/ ) Li and colleagues recruited adults over the internet and provided mindfulness training through text messaging. They measured insomnia, pain, and dysregulated eating.

 

They found that mindfulness training compared to a wait-list control condition resulted in resulted in significant decreases in anxiety, depression, insomnia, pain, and dysregulated eating and these improvements were sustained 3 months after the end of training. They found a wide array of improvements from mindfulness training. Particularly important from the perspective of eating disorders were the findings of reductions in depression and dysregulated eating. This suggests that mindfulness training reduces the likelihood of the development of an eating disorder.

 

“When walking, walk. When eating, eat.” rashaski · Zen Proverb

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Li AC, Wong KK, Chio FH, Mak WW, Poon LW. Delivering Mindfulness-Based Interventions for Insomnia, Pain, and Dysfunctional Eating Through a Text Messaging App: Three Randomized Controlled Trials Investigating the Effectiveness and Mediating Mechanisms. J Med Internet Res. 2022 May 3;24(5):e30073. doi: 10.2196/30073. PMID: 35503653; PMCID: PMC9115660.

 

Abstract

Background

Although text messaging has the potential to be the core intervention modality, it is often used as an adjunct only. To improve health and alleviate the distress related to insomnia, pain, and dysregulated eating of people living in urban areas, text messaging–based mindfulness-based interventions were designed and evaluated in 3 randomized controlled trials.

Objective

This study investigated the effectiveness and mediating mechanisms of text messaging–based mindfulness-based interventions for people with distress related to insomnia, pain, or dysregulated eating.

Methods

In these trials, 333, 235, and 351 participants were recruited online and randomized to intervention and wait-list control conditions for insomnia, pain, and dysregulated eating, respectively. Participants experienced 21 days of intervention through WhatsApp Messenger. Participants completed pre-, post-, 1-month follow-up, and 3-month follow-up self-report questionnaires online. The retention rates at postmeasurements were 83.2% (139/167), 77.1% (91/118), and 72.9% (129/177) for intervention groups of insomnia, pain, and dysregulated eating, respectively. Participants’ queries were answered by a study technician. Primary outcomes included insomnia severity, presleep arousal, pain intensity, pain acceptance, and eating behaviors. Secondary outcomes included mindfulness, depression, anxiety, mental well-being, and functional impairments. Mindfulness, dysfunctional beliefs and attitudes about sleep, pain catastrophizing, and reactivity to food cues were hypothesized to mediate the relationship between the intervention and outcomes.

Results

For all 3 studies, the intervention groups showed significant improvement on most outcomes at 1-month follow-up compared to their respective wait-list control groups; some primary outcomes (eg, insomnia, pain, dysregulated eating indicators) and secondary outcomes (eg, depression, anxiety symptoms) were sustained at 3-month follow-up. Medium-to-large effect sizes were found at postassessments in most outcomes in all studies. In the intervention for insomnia, mediation analyses showed that dysfunctional beliefs and attitudes about sleep mediated the effect of the intervention on all primary outcomes and most secondary outcomes at both 1-month and 3-month follow-ups, whereas mindfulness mediated the intervention effect on presleep arousal at 1-month and 3-month follow-ups. In the intervention for pain, pain catastrophizing mediated the effect of intervention on pain intensity and functioning at both 1-month and 3-month follow-ups, whereas mindfulness only mediated the effect of intervention on anxiety and depressive symptoms. In the intervention for dysregulated eating, power of food mediated the effect of intervention on both uncontrolled and emotional eating at both 1-month and 3-month follow-ups and mindfulness was found to mediate the effect on depressive symptoms at both 1-month and 3-month follow-ups.

Conclusions

These 3 studies converged and provided empirical evidence that mindfulness-based interventions delivered through text messaging are effective in improving distress related to sleep, pain, and dysregulated eating. Text messaging has the potential to be a core intervention modality to improve various common health outcomes for people living a fast-paced lifestyle.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115660/

 

Improve Flow, Communication Skills, and Safety Attitudes of Surgeons with Mindfulness

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Improve Flow, Communication Skills, and Safety Attitudes of Surgeons with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Once you can communicate with yourself, you’ll be able to communicate outwardly with more clarity. The way in is the way out.”― Thích Nhất Hạnh

 

Stress is epidemic in the western workplace with almost two thirds of workers reporting high levels of stress at work. In high stress occupations, like healthcare, burnout is all too prevalent. Preventing burnout has to be a priority. Contemplative practices have been shown to reduce the psychological and physiological responses to stress and improve well-being. Indeed, mindfulness has been shown to be helpful in treating and preventing burnout, increasing resilience, and improving sleep. Mindfulness has also been shown to improve flow, a state of mind that is characterized by a complete absorption with the task at hand, often resulting in enhanced skilled performance. Thus, there is a need to investigate how mindfulness effects doctors’ well-being, performance, and flow.

 

In today’s Research News article “Focused-Attention Meditation Improves Flow, Communication Skills, and Safety Attitudes of Surgeons.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099589/ ) Chen and colleagues recruited surgeons and randomly assigned them to either a wait-list control condition or to receive 50 minutes of focused meditation practice 3 times per week for 8 weeks. They were measured before and after training for work-related flow, communications skills, safety attitudes, and clinical adverse events.

 

They found that in comparison to baseline and the wait-list control group the surgeons who received mindfulness training had significantly increased levels of work-related flow, communications skills, and safety attitudes. Eight weeks after the training the mindfulness trained surgeons had significantly lower levels of clinical adverse events.

 

Hence, mindfulness training significantly improved surgeons’ flow and medical performance. This further suggests that mindfulness training should be recommended for physicians.

 

“physicians could use mindfulness as a stand-alone technique prior to engaging in bad news delivery to patients.” – AMRA

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Chen H, Liu C, Zhou F, Cao XY, Wu K, Chen YL, Liu CY, Huang DH, Chiou WK. Focused-Attention Meditation Improves Flow, Communication Skills, and Safety Attitudes of Surgeons. Int J Environ Res Public Health. 2022 Apr 27;19(9):5292. doi: 10.3390/ijerph19095292. PMID: 35564687; PMCID: PMC9099589.

 

Abstract

Objective: Patient safety is a worldwide problem and a focus of academic research. Human factors and ergonomics (HFE) is an approach to improving healthcare work systems and processes. From the perspective of the cognitive ergonomics of HFE, the aim of this study is to improve the flow level, communication skills, and safety attitudes of surgeons through focused-attention meditation (FAM) training, thus helping to reduce adverse clinical events. Methods: In total, 140 surgeons were recruited from three hospitals in China and randomly divided into two groups (FAM group and control group). The FAM group received 8 weeks of FAM training, while the control group was on the waiting list and did not receive any interventions. Three scales (WOLF, LCSAS, and SAQ-C) were used to measure the data of three variables (flow, communication skills, and safety attitude), respectively, at two times, before and after the intervention (pre-test and post-test). The incidence of adverse events during the intervention was also collected for both groups. Results: The ANOVA results showed that all three variables had a significant main effect of time and significant interactions between time and group. The independent-sample T-test results showed that the incidence of adverse events during the intervention was significantly lower in the FAM group than in the control group. Conclusions: The intervention of FAM could significantly improve surgeons’ flow levels, communication skills, and safety attitudes, potentially helping to reduce adverse clinical events.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099589/

 

Improve Immune function with a Meditation Retreat

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Improve Immune function with a Meditation Retreat

 

By John M. de Castro, Ph.D.

 

“meditative practice enhanced immune function without activating inflammatory signals. This suggests that meditation, as a behavioral intervention, may be an effective component in treating diseases characterized by increased inflammatory responsiveness with a weakened immune system.” – Vijayendran Chandran

 

The immune system is designed to protect the body from threats like stress, infection, injury, and toxic chemicals. One of its tools is the Inflammatory response. This response works quite well for short-term infections and injuries. But when inflammation is protracted and becomes chronic, it can itself become a threat to health. It can produce autoimmune diseases such as colitis, Chron’s disease, arthritis, heart disease, increased cancer risk, lung disease, sleep disruption, gum disease, decreased bone health, psoriasis, and depression.

 

When the immune system attacks the liver, it produces autoimmune hepatitis which damages the liver. It is rare but affects women four times more often than men. Mind-body techniques such as yoga, Tai Chi and meditation have been shown to adaptively reduce the inflammatory response. So, it would seem reasonable that mindfulness training may be effective in treating autoimmune hepatitis.

 

In today’s Research News article “). Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713789/ ) Chandran and colleagues recruited healthy participants in an 8-day meditation, yoga, and vegan diet retreat. Blood was drawn for genomic analysis 5 weeks before, immediately before and after the retreat and 3 months later.

 

They found that there was lessened activity in genes associated with oxidative stress, detoxification, and cell cycle regulation and increased activity in genes associated with the immune response but no change in genes associated with inflammation. Hence, participation in the meditation, yoga, and vegan diet retreat produced genetic expressions representative of improved immune response without inflammation.

 

So, improve immune function with a meditation retreat.

 

“multiple genes related to the immune system were activated — dramatically — when you do Inner Engineering practices,” – Vijayendran Chandran

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Twitter @MindfulResearch

 

Study Summary

 

Chandran, V., Bermúdez, M. L., Koka, M., Chandran, B., Pawale, D., Vishnubhotla, R., Alankar, S., Maturi, R., Subramaniam, B., & Sadhasivam, S. (2021). Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat. Proceedings of the National Academy of Sciences of the United States of America, 118(51), e2110455118. https://doi.org/10.1073/pnas.2110455118

 

SIGNIFICANCE

Several studies on the impact of yoga and meditation on mental and physical health have demonstrated beneficial effects. However, the potential molecular mechanisms and critical genes involved in this beneficial outcome have yet to be comprehensively elucidated. This study identified and characterized the transcriptional program associated with advanced meditation practice, and we bioinformatically integrated various networks to identify meditation-specific core network. This core network links several immune signaling pathways, and we showed that this core transcriptional profile is dysfunctional in multiple sclerosis and severe COVID-19 infection. Very importantly, we demonstrated that the meditative practice enhanced immune function without activating inflammatory signals. Together, these results make meditation an effective behavioral intervention for treating various conditions associated with a weakened immune system.

Keywords: meditation, immune, Isha yoga, Inner Engineering, COVID-19

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ABSTRACT

The positive impact of meditation on human well-being is well documented, yet its molecular mechanisms are incompletely understood. We applied a comprehensive systems biology approach starting with whole-blood gene expression profiling combined with multilevel bioinformatic analyses to characterize the coexpression, transcriptional, and protein–protein interaction networks to identify a meditation-specific core network after an advanced 8-d Inner Engineering retreat program. We found the response to oxidative stress, detoxification, and cell cycle regulation pathways were down-regulated after meditation. Strikingly, 220 genes directly associated with immune response, including 68 genes related to interferon signaling, were up-regulated, with no significant expression changes in the inflammatory genes. This robust meditation-specific immune response network is significantly dysregulated in multiple sclerosis and severe COVID-19 patients. The work provides a foundation for understanding the effect of meditation and suggests that meditation as a behavioral intervention can voluntarily and nonpharmacologically improve the immune response for treating various conditions associated with excessive or persistent inflammation with a dampened immune system profile.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713789/