Improve the Symptoms of Parkinson’s Disease with Mind-Body Practices

May 26, 2020July 19, 2020 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“The mind-body connection recognizes that emotional, mental, and behavioral factors can directly affect our health, and mind-body techniques can improve quality of life and may help reduce symptoms of disease.” – Emily Downward

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications which can reduce life expectancy, such as falls, choking, and cardiovascular problems. Parkinson’s Disease (PD) also has psychological effects, especially cognitive decline, anxiety, and depression. All of these symptoms result in a marked reduction in the quality of life.

In today’s Research News article “The Impact of Mind-body Exercises on Motor Function, Depressive Symptoms, and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981975/), Jin and colleagues review, summarize, and perform a meta-analysis of the effectiveness of mind-body practices for the relief of the symptoms of Parkinson’s Disease. They selected randomized controlled trials with Tai Chi, Qigong and Yoga practices for patients with Parkinson’s Disease over 40 years of age. They identified 22 studies with a total of 1199 participants, 18 of which employed Tai Chi and Qigong practices and 4 employed Yoga practice.

They report that the studies found that the mind-body practices produced significant improvements in overall Parkinson’s Disease motor function, walking ability, balance, depression, and quality of life. Hence, the published research studies demonstrate that mind-body practices significantly improve the physical and psychological symptoms of Parkinson’s Disease.

Tai Chi and Qigong practices have been demonstrated in prior research to improve balance, walking ability, depression, and quality of life in a variety of healthy and sick people. In addition yoga practice has been demonstrated to improve balance, walking ability, depression and quality of life in various populations. The present study extends these findings to patients with Parkinson’s Disease. These practices appear to be a safe and effective treatment to relieve the symptoms and suffering of patients with Parkinson’s Disease.

So, improve the symptoms of Parkinson’s Disease with mind-body practices.

“Mindfulness-based interventions have the ability to reprogram brain conditioning and alter the ways in which we respond to the world. Parkinson’s patients can benefit immensely from this method as a means of decreasing stress and anxiety while slowly increasing quality of life.” – Alana Kessler

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Jin, X., Wang, L., Liu, S., Zhu, L., Loprinzi, P. D., & Fan, X. (2019). The Impact of Mind-body Exercises on Motor Function, Depressive Symptoms, and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-analysis. International journal of environmental research and public health, 17(1), 31. https://doi.org/10.3390/ijerph17010031

Abstract

Purpose: To systematically evaluate the effects of mind-body exercises (Tai Chi, Yoga, and Health Qigong) on motor function (UPDRS, Timed-Up-and-Go, Balance), depressive symptoms, and quality of life (QoL) of Parkinson’s patients (PD). Methods: Through computer system search and manual retrieval, PubMed, Web of Science, The Cochrane Library, CNKI, Wanfang Database, and CQVIP were used. Articles were retrieved up to the published date of June 30, 2019. Following the Cochrane Collaboration System Evaluation Manual (version 5.1.0), two researchers independently evaluated the quality and bias risk of each article, including 22 evaluated articles. The Pedro quality score of 6 points or more was found for 86% (19/22) of these studies, of which 21 were randomized controlled trials with a total of 1199 subjects; and the trial intervention time ranged from 4 to 24 weeks. Interventions in the control group included no-intervention controls, placebo, waiting-lists, routine care, and non-sports controls. Meta-analysis was performed on the literature using RevMan 5.3 statistical software, and heterogeneity analysis was performed using Stata 14.0 software. Results: (1) Mind-body exercises significantly improved motor function in PD patients, including UPDRS (SMD = −0.61, p < 0.001), TUG (SMD = −1.47, p < 0.001) and balance function (SMD = 0.79, p < 0.001). (2) Mind-body exercises also had significant effects on depression (SMD = −1.61, p = 0.002) and QoL (SMD = 0.66, p < 0.001). (3) Among the indicators, UPDRS (I2 = 81%) and depression (I2 = 91%) had higher heterogeneity; according to the results of the separate combined effect sizes of TUG (I2 = 29%), Balance (I2 = 16%) and QoL (I2 = 35%), it shows that the heterogeneity is small; (4) After meta-regression analysis of the age limit and other possible confounding factors, further subgroup analysis showed that the reason for the heterogeneity of UPDRS motor function may be related to the sex of PD patients and severity of the disease; the outcome of depression was heterogeneous. The reason for this may be the use of specific drugs in the experiment and the duration of intervention in the trial. Conclusion: (1) Mind-body exercises were found to have significant improvements in motor function, depressive symptoms, and quality of life in patients with Parkinson’s disease, and can be used as an effective method for clinical exercise intervention in PD patients. (2) Future clinical intervention programs for PD patients need to fully consider specific factors such as gender, severity of disease, specific drug use, and intervention cycle to effectively control heterogeneity factors, so that the clinical exercise intervention program for PD patients is objective, scientific, and effective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981975/

Improve Parkinson’s Disease Symptoms with Tai Chi

April 20, 2020 psyjdc Leave a comment

Improve Parkinson’s Disease Symptoms with Tai Chi

By John M. de Castro, Ph.D.

“tai chi can be used as an add-on to current physical therapies and medications to ease some of the key problems faced by people with Parkinson’s disease.” – Peter Wayne

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

In today’s Research News article “Tai Chi versus routine exercise in patients with early- or mild-stage Parkinson’s disease: a retrospective cohort analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013627/), Li and colleagues recruited adult patients with Parkinson’s Disease and randomly assigned them to receive either 90 minutes, 3 times per week for two months of routine exercise or of a 6-move Yang Tai Chi practice. They were measured before and after training for walking speed, up-and-go from chair, functional reach, functional activities, and falls over 6-month periods.

They found that both the exercise and Tai Chi practices produced significant improvements in walking speed, up-and-go from chair, and functional reach and significantly decreased numbers of falls over the 6-month period following treatment. But the Tai Chi group had superior outcomes compared to routine exercise. In addition, a greater number of Tai Chi participants were able to withdraw from medication or reduce medication doses. No adverse events were recorded.

The results suggest that both exercise and Tai Chi practices produce significant improvements in the motor symptoms of Parkinson’s Disease but Tai Chi practice produces even greater improvements. The reduction in falls observed in the Tai Chi group are particularly important as falls are a significant contributor to injuries and mortality in Parkinson’s Disease patients.

It’s important to note that Tai Chi is a gentle and safe mindfulness practice. It is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It is inexpensive to administer, can be performed in groups or alone, at home or in a facility, and can be quickly learned. In addition, it can be practiced in social groups. This can make it fun, improving the likelihood of long-term engagement in the practice. Hence, Tai Chi practice would appear to be a superior practice to be added to routine treatment for the improvements of the symptoms of Parkinson’s Disease.

So, improve Parkinson’s Disease symptoms with Tai Chi.

“Daily Tai Chi practice is extremely helpful to those with chronic ailments and illnesses like cancer, heart disease, stroke, Parkinson’s, Alzheimer’s, osteoporosis, peripheral neuropathy, respiratory problems and irritable bowel syndrome to name a few,” – Mwezo Kujiweza

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Li, Q., Liu, J., Dai, F., & Dai, F. (2020). Tai Chi versus routine exercise in patients with early- or mild-stage Parkinson’s disease: a retrospective cohort analysis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 53(2), e9171. https://doi.org/10.1590/1414-431X20199171

Abstract

Parkinson’s disease cannot be cured but symptoms can be improved by making use of physical therapy. The objective of the study was to compare the effect of routine exercises and Tai Chi on physical and clinical performance in elderly people suffering from Parkinson’s disease. Data from interviews, physical and clinical performance, and levodopa consumption of 500 patients with confirmed Parkinson’s disease (severity level I to III) were collected and analyzed. Participants who received 80 min/day Tai Chi 3 times/week for 2 months were included in the Tai Chi (TC) group (n=250) and those who received 90 min/day routine exercise 3 times/week for 2 months were included in routine exercise (RE) group (n=250). Timed up-and-go, 50-foot speed walk, and functional reach were improved by Tai Chi and routine exercise (P<0.05 for all) but intensities of Tai Chi for improvement of such parameters was higher than routine exercise. Incidence of falls was decreased by both physical therapies (P<0.05 for all) but more for the TC group (P<0.0001, q=38.512). In the TC group, at the end of follow-up, 22 (9%) patients were successful in withdrawal of levodopa treatment. Also, the dose of levodopa was decreased in patients of the TC group who had to continue levodopa. Tai Chi had the potential to slow down the progression of symptoms of Parkinson’s disease and delayed the introduction of levodopa (level of evidence: III).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013627/

Improve Balance and Mobility and Prevent Falls in Parkinson’s Disease Patients with Tai Chi

June 14, 2019July 19, 2020 psyjdc Leave a comment

Improve Balance and Mobility and Prevent Falls in Parkinson’s Disease Patients with Tai Chi

By John M. de Castro, Ph.D.

“There is still so much to learn from research about exactly how exercise improves the physical and mental well-being of people with living with Parkinson’s disease, as well as which combinations or activities yield the best outcomes, but there is no doubt whatsoever that exercise remains one of the best therapies for preserving and enhancing quality of life.” – Davis Phinney

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

In today’s Research News article “Effects of Tai Chi Exercise on Reducing Falls and Improving Balance Performance in Parkinson’s Disease: A Meta-Analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409066/), Liu and colleagues review, summarize, and perform a meta-analysis on the effectiveness of Tai Chi practice to improve balance and mobility and reduce falls in Parkinson’s Disease (PD) patients. They found and reviewed 5 published randomized controlled trials that compared Tai Chi practice to no intervention, stretching/resistance training, and walking control conditions.

They report that the trials found that in comparison to baseline and the control conditions Tai Chi practice significantly improved balance and functional mobility in the Parkinson’s Disease patients and reduced the number who experienced a fall. This is important as the compromised motor ability of patients with Parkinson’s Disease makes them much more vulnerable to falls and the resultant compromised health. By improving balance and mobility in these patients Tai Chi practice produces enhanced health and well-being.

The results of the published research strongly suggests that Tai Chi practice should be routinely prescribed for patients with Parkinson’s Disease. Tai Chi is a gentle and safe mindfulness practice. It is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It is inexpensive to administer, can be performed in groups or alone, at home or in a facility, and can be quickly learned. In addition, it can be practiced in social groups. This can make it fun, improving the likelihood of long-term engagement in the practice. So, Tai Chi practice would appear to be an excellent gentle practice to improve the well-being of patients with Parkinson’s Disease.

So, improve balance and mobility and prevent falls in Parkinson’s Disease patients with Tai Chi.

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Liu, H. H., Yeh, N. C., Wu, Y. F., Yang, Y. R., Wang, R. Y., & Cheng, F. Y. (2019). Effects of Tai Chi Exercise on Reducing Falls and Improving Balance Performance in Parkinson’s Disease: A Meta-Analysis. Parkinson’s disease, 2019, 9626934. doi:10.1155/2019/9626934

Abstract

Introduction

Parkinson’s disease (PD) is a common neurodegenerative disorder that may increase the risk of falls, functional limitation, and balance deficits. Tai Chi was used as an option for improving balance in people with PD. The aim of this meta-analysis was to evaluate the effects of Tai Chi on falls, balance, and functional mobility in individuals with PD.

Method

The literature search was conducted in PubMed, the Cochrane Library, CINAHL, PEDro, Medline, Embase, sportDISCUS, Trip, and the National Digital Library of Theses and Dissertations in Taiwan. Randomized controlled trials (RCTs) analyzing the effects of Tai Chi, compared to no intervention or to other physical training, on falls, functional mobility, and balance in PD patients were selected. The outcome measurements included fall rates, Berg Balance Scale (BBS), Functional Reach (FR) test, and the Timed Up and Go (TUG) test. Two reviewers independently assessed the methodological quality and extracted data from the studies using the PEDro scale.

Results

Five RCTs that included a total of 355 PD patients were included in this review. The quality of evidence in these studies was rated as moderate to high. Compared to no intervention or other physical training, Tai Chi significantly decreased fall rates (odds ratio = 0.47, 95% confidence interval (CI) 0.30 to 0.74, and p=0.001) and significantly improved balance and functional mobility (BBS mean difference (MD) = 3.47, 95% CI 2.11 to 4.80, and p < 0.001; FR MD = 3.55 cm, 95% CI 1.88 to 5.23, and p < 0.001; TUG MD = −1.06 s, 95% CI −1.61 to −0.51, and p < 0.001) in people with PD.

Conclusion

This meta-analysis provides moderate- to high-quality evidence from five RCTs that Tai Chi could be a good physical training strategy for preventing falls and improving balance and functional mobility in people with PD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409066/

Improve Parkinson’s Disease Symptoms with Tai Chi

September 8, 2018 psyjdc Leave a comment

Improve Parkinson’s Disease Symptoms with Tai Chi

By John M. de Castro, Ph.D.

“It isn’t every day that an effective new treatment for some Parkinson’s disease symptoms comes along. Especially one that is safe, causes no adverse side effects, and may also benefit the rest of the body and the mind. . . . tai chi may improve balance and prevent falls among people with Parkinson’s disease.” – Peter Wayne

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

In today’s Research News article “The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson’s disease: A systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618798/ ), Song and colleagues reviewed, summarized, and performed a meta-analysis of the published research literature on the effectiveness of Tai Chi practice for the relief of the symptoms of Parkinson’s Disease. They found 21 studies, including 823 total patients with an average age of 67.5 years, 15 of which were randomized controlled trials and 8 contained active control conditions. No adverse events were reported.

They found that Tai Chi practice produced significant improvements in motor functions, balance, Timed-Up-and-Go (getting up from chair, walking 3 meters, and sitting back down), walking speed, and falls. Tai Chi practice was also found to significantly improve the psychological state of the patients with significantly lower levels of depression and increases in quality of life. Hence, Tai Chi practice produced important improvements in the motor ability and psychological state of patients with Parkinson’s Disease.

These findings are significant and important suggesting that Tai Chi practice is a safe and effective treatment for the symptoms of Parkinson’s Disease. Tai Chi and Qigong are ancient mindfulness practices involving slow prescribed movements. They are gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice.

So, improve Parkinson’s Disease symptoms with Tai Chi.

“There are many obvious reasons everyone with Parkinson’s should be doing Tai Chi, but it’s the ones that are not yet obvious that may be the most intriguing. One obvious reason is that Tai Chi is the most powerful balance and coordination enhancing exercise known. In many studies at major universities Tai Chi was found to be TWICE as effective in reducing falls as the other balance enhancing exercises being studied.” – Sherri Woodbridge

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Song, R., Grabowska, W., Park, M., Osypiuk, K., Vergara, G., Bonato, P., … Wayne, P. (2017). The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders, 41, 3–13. http://doi.org/10.1016/j.parkreldis.2017.05.019

Highlights

Tai Chi/Qigong is a mind-body intervention that has the potential to address motor and non-motor symptoms associated with Parkinson’s disease.
Mixed results for motor outcomes have been reported, while even less attention has been devoted to systematically evaluating the effects of Tai Chi/Qigong on non-motor outcomes.
Our meta-analyses indicate clinically relevant effect sizes in favor of Tai Chi/Qigong for motor function, balance, and quality of life, and significant effect sizes persisted even when comparisons were limited to active controls.

Abstract

Purpose

To systematically evaluate and quantify the effects of Tai Chi/Qigong (TCQ) on motor (UPDRS III, balance, falls, Timed-Up-and-Go, and 6-Minute Walk) and non-motor (depression and cognition) function, and quality of life (QOL) in patients with Parkinson’s disease (PD).

Methods

A systematic search on 7 electronic databases targeted clinical studies evaluating TCQ for individuals with PD published through August 2016. Meta-analysis was used to estimate effect sizes (Hedge’s g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed by two raters.

Results

Our search identified 21 studies, 15 of which were RCTs with a total of 755 subjects. For RCTs, comparison groups included no treatment (n=7, 47%) and active interventions (n=8, 53%). Duration of TCQ ranged from 2 to 6 months. Methodological bias was low in 6 studies, moderate in 7, and high in 2. Fixed-effect models showed that TCQ was associated with significant improvement on most motor outcomes (UPDRS III [ES=-0.444, p<.001], balance [ES=0.544, p<.001], Timed-Up-and-Go [ES=−0.341, p=.005], 6MW [ES=−0.293, p=.06]), falls [ES=−.403, p=.004], as well as depression [ES=−0.457, p=.008] and QOL [ES=−0.393, p<.001], but not cognition [ES= −0.225, p=.477]). I2 indicated limited heterogeneity. Funnel plots suggested some degree of publication bias.

Conclusion

Evidence to date supports a potential benefit of TCQ for improving motor function, depression and QOL for individuals with PD, and validates the need for additional large-scale trials.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618798/

Improve the Symptoms of Parkinson’s Disease with Yoga

August 7, 2018 psyjdc Leave a comment

Improve the Symptoms of Parkinson’s Disease with Yoga

By John M. de Castro, Ph.D.

“While there is no evidence that regular yoga practice has an effect on the systems in the brain that are related to Parkinson’s disease, patients report improvements in their quality of life.” – Lynn Burgess

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

Parkinson’s Disease’s (PD) physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications which can reduce life expectancy, such as falls, choking, and cardiovascular problems. Parkinson’s Disease (PD) also has psychological effects, especially cognitive decline, anxiety, and depression. All of these symptoms result in a marked reduction in the quality of life.

In today’s Research News article “Functional Improvements in Parkinson’s Disease Following a Randomized Trial of Yoga.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009016/ ), Van Puymbroeck and colleagues recruited patients with Parkinson’s Disease and also reported a substantial fear of falling. They were randomly assigned to receive either an 8-week yoga practice or to a wait list control condition. Yoga practice met twice weekly and included postures, meditation, and breathing exercises. They were measured before and after training for Parkinson’s Disease symptoms, Parkinson’s Disease quality of life, balance control, functional gait, and freezing gait. Freezing gait is common in Parkinson’s Disease and is “a brief, episodic absence or marked reduction of forward progression of the feet despite the intention to walk.”

They found that in comparison to baseline and the wait-list group, the yoga group had significant improvements in functional gait, Parkinson’s Disease motor symptoms, freezing gait, and balance control, all with moderate effect sizes. Hence yoga practice produced significant improvements in the motor and balance ability of patients with Parkinson’s Disease. This would predict that yoga practice would reduce falls and improve the longevity of PD patients.

It should be noted that the control condition did not contain any active components. This leaves open the possibility of contamination by placebo effects and biases. Future research should employ an active control condition such as aerobic exercise. Nevertheless, the results are very encouraging that yoga practice may well be highly beneficial for patients with Parkinson’s Disease.

So, improve the symptoms of Parkinson’s disease with yoga.

“Several recent studies have suggested that yoga may offer significant relief to people with Parkinson’s disease. . . .yoga not only improved psychological well-being, it also had an effect on the mobility problems experienced by many patients.” – Sarah Alender

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Van Puymbroeck, M., Walter, A., Hawkins, B. L., Sharp, J. L., Woschkolup, K., Urrea-Mendoza, E., … Schmid, A. A. (2018). Functional Improvements in Parkinson’s Disease Following a Randomized Trial of Yoga. Evidence-Based Complementary and Alternative Medicine : eCAM, 2018, 8516351. http://doi.org/10.1155/2018/8516351

Abstract

Individuals with Parkinson’s Disease (PD) experience significant limitations in motor function, functional gait, postural stability, and balance. These limitations often lead to higher incidences of falls, which have significant complications for individuals with PD. Yoga may improve these functional deficits in individuals with PD. The objective of this study was to determine changes in motor function, functional gait, postural stability, and balance control for community dwelling individuals with PD. This randomized, wait-list controlled pilot study examined the influence of an 8-week yoga intervention for people with PD who met the following inclusion criteria: endorsing a fear of falling, being able to speak English, scoring 4/6 on the minimental state exam, and being willing to attend the intervention twice weekly for 8-weeks. Participants in the yoga group (n=15) experienced improvements in motor function, postural stability, functional gait, and freezing gait, as well as reductions in fall risk. Participants in the wait-list control (n=12) also significantly improved in postural stability, although their fall risk was not reduced. Individuals in the yoga group significantly reduced their fall risk. An 8-week yoga intervention may reduce fall risk and improve postural stability, and functional and freezing gait in individuals with PD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009016/

Improve Parkinson’s Disease with Group Tai Chi Practice

October 21, 2017 psyjdc Leave a comment

Improve Parkinson’s Disease with Group Tai Chi Practice

By John M. de Castro, Ph.D.

“Tai chi, an ancient martial art characterized by slow, flowing movement and meditation, helps improve balance and movement control for people with Parkinson’s disease.” – Tara Parker-Pope

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

There are no cures for Parkinson’s Disease or even treatments to slow its progression. There are only treatments that can produce symptomatic relief. So, there is a need to discover new and different treatments. Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients. Tai Chi and Qigong are ancient mindfulness practices involving slow prescribed movements. They are gentle and completely safe, can be used with the elderly and sickly, is inexpensive to administer, can be performed in groups or alone, at home or in a facility or even public park, and can be quickly learned. In addition, it can also be practiced in social groups without professional supervision. This can make it fun, improving the likelihood of long-term engagement in the practice. In addition, Qigong has been shown to improve the symptoms of Parkinson’s Disease. Hence, Tai Chi and Qigong may be an excellent treatment for the symptoms of Parkinson’s Disease.

The parameters of Tai Chi and Qigong practice that maximize its benefits for the relief of the symptoms of Parkinson’s Disease have not been explored. In today’s Research News article “The Effects of Group-Based versus Individual-Based Tai Chi Training on Nonmotor Symptoms in Patients with Mild to Moderate Parkinson’s Disease: A Randomized Controlled Pilot Trial.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546134/, Yang and colleagues investigate the relative effectiveness of Tai Chi practiced alone or in group contexts. They recruited patients with Parkinson’s Disease and randomly assigned them to practice Tai Chi for 45 minutes, 3 times per week, for 13 weeks either alone or in a group of 6 to 7 participants. Home practice was also prescribed. They were measured before and after training for cognitive ability, depression, and the non-motor symptoms of Parkinson’s Disease including cardiovascular, sleep/fatigue, mood/cognition, perceptual problems, attention/memory, gastrointestinal, urinary, and sexual function.

They found that after training both groups showed significant improvement in the overall non-motor symptoms of Parkinson’s Disease and particularly in sleep. Only the group Tai Chi practice participants, however, showed a significant improvement in cognitive (thinking) performance. In addition, the group Tai Chi practice participants had significantly greater compliance with home practice. Hence, Tai Chi regardless of whether practiced in groups of individually improved the non-motor symptoms of Parkinson’s Disease, but practicing it in groups appears to produce an additional improvement in the ability of the patients to process information (Cognition) and improve their likelihood of practicing at home.

The present results, as prior research, make it clear that Tai Chi practice is helpful in relieving the symptoms of Parkinson’s Disease. But, the results also make it clear that practicing in a group may be superior to practicing alone. Group Tai Chi practice may be more fun and engaging, potentiating its effectiveness. Its effectiveness for cognition is particularly important as cognitive decline is a common symptom of the progression of Parkinson’s Disease and complicates the patient’s ability to carry on normal life functions.

So, improve Parkinson’s Disease with group Tai Chi practice.

“Falls are common in people with Parkinson’s, and they can cause serious injuries, including fractures and concussions. Studies show falls are the main cause of hospitalizations in Parkinson’s patients. People in the tai chi group reported half the number of falls compared to those who were taking resistance training and two-thirds fewer falls than people who were doing light stretching exercises.” – Brenda Goodman

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

Yang, J. H., Wang, Y. Q., Ye, S. Q., Cheng, Y. G., Chen, Y., & Feng, X. Z. (2017). The Effects of Group-Based versus Individual-Based Tai Chi Training on Nonmotor Symptoms in Patients with Mild to Moderate Parkinson’s Disease: A Randomized Controlled Pilot Trial. Parkinson’s Disease, 2017, 8562867. http://doi.org/10.1155/2017/8562867

Abstract

Objective

To compare the effects of group-based and individual-based Tai Chi training on nonmotor symptoms in patients with mild to moderate Parkinson’s disease.

Design

Randomized controlled pilot study.

Methods

36 community-dwelling patients with Parkinson’s disease (PD) were randomly assigned to either group-based training group (n = 19) or individual-based group (n = 17). Both groups received same content of Tai Chi training 3 times a week for 13 weeks. Participants were also asked to perform home exercises daily. The Non-Motor Symptoms Scale was used to assess global nonmotor symptoms change. Sleep quality, depression, and cognition were evaluated by Parkinson’s Disease Sleep Scale, Hamilton Depression Scale, and Beijing version-Montreal Cognitive Assessment, respectively. Home exercise compliance was recorded.

Results

There was no significant difference between two groups at baseline. After 13 weeks, there were no statistical significance between two groups. However, the within-group effect was different. Participants in group-based and individual-based groups showed a significant improvement on global nonmotor symptoms (P < 0.001, P = 0.004) and sleep (P < 0.001, P < 0.001). But only group-based training patients presented a significant improvement in cognitive impairment compared with baseline (P = 0.002, P − 0.116). For depression, no group gained a significant improvement(P = 0.123, P = 0.170). Group-based participants had a higher home-exercise compliance rate (HeCR) than individual-based participants did (P = 0.019), and HeCR showed a moderate correlation with MoCA-BJ and NMSS scores changes in this study.

Conclusion

Group-based Tai Chi training is considered to be a more effective and a more labor-saving method in the clinical settings, and patients tend to have a higher compliance rate in their home exercise program

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546134/

Improve Parkinson’s Disease with Mindfulness

July 18, 2017July 18, 2017 psyjdc Leave a comment

Improve Parkinson’s Disease with Mindfulness

By John M. de Castro, Ph.D.

“A practical and powerful way to reduce stress is to become more mindful which, simply put, means being present in the moment rather than agonizing over the past or anticipating the future. Once stress levels are well under control, symptoms of Parkinson’s will have enormous difficulty presenting themselves. When people experience stress, their symptoms get much worse. When stress levels are under control, symptoms subside.” – Robert Rogers

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications which can reduce life expectancy, such as falls, choking, and cardiovascular problems. Parkinson’s Disease (PD) also has psychological effects, especially anxiety and depression. All of these symptoms result in a marked reduction in the quality of life.

Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients. In addition, stress is known to exacerbate the symptoms of PD. So, it would make sense that Mindfulness-Based Stress Reduction (MBSR), a mindfulness training that was developed specifically for stress reduction, would be effective for relieving some of the symptoms of PD. In today’s Research News article “Mindfulness-based stress reduction in Parkinson’s disease: a systematic review.” See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433018/, McLean and colleagues review the published research literature on the effectiveness of an 8-week program of MBSR for patients with PD.

As it turns out, the research is sparse. They were only able to identify 3 published articles which described 2 controlled trials, both of small size and with non-active control groups. The studies reported that MBSR participants, in comparison to controls, had improved motor ability, mindfulness, and quality of life with PD, and decreases in depression. One study found potentially beneficial changes in the patients’ brains in the MBSR group.

The scarce published research to date is promising and suggests that MBSR may be a beneficial treatment for patients with Parkinson’s Disease (PD) producing improvements in motor ability, psychological well-being, and quality of life. There is obviously a need for larger and better controlled trials. But, the research suggests that such research is warranted. Mindfulness training may be helpful in easing some of the symptom burden that plagues PD sufferers.

So, improve Parkinson’s disease with mindfulness.

“Mindfulness training, as taught by qualified and experienced teachers, may offer a more participatory medicine, empowering the individual by engagement to learn how to strengthen internal resources to help cope with chronic disease. Mindfulness training may help to restore some degree of self-determination in the experience of living with PD.” – Margaret Tuchman

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

Study Summary

McLean, G., Lawrence, M., Simpson, R., & Mercer, S. W. (2017). Mindfulness-based stress reduction in Parkinson’s disease: a systematic review. BMC Neurology, 17, 92. http://doi.org/10.1186/s12883-017-0876-4

Abstract

Background

Mindfulness based stress reduction (MBSR) is increasingly being used to improve outcomes such as stress and depression in a range of long-term conditions (LTCs). While systematic reviews on MBSR have taken place for a number of conditions there remains limited information on its impact on individuals with Parkinson’s disease (PD).

Methods

Medline, Central, Embase, Amed, CINAHAL were searched in March 2016. These databases were searched using a combination of MeSH subject headings where available and keywords in the title and abstracts. We also searched the reference lists of related reviews. Study quality was assessed based on questions from the Cochrane Collaboration risk of bias tool.

Results

Two interventions and three papers with a total of 66 participants were included. The interventions were undertaken in Belgium (n = 27) and the USA (n = 39). One study reported significantly increased grey matter density (GMD) in the brains of the MBSR group compared to the usual care group. Significant improvements were reported in one study for a number of outcomes including PD outcomes, depression, mindfulness, and quality of life indicators. Only one intervention was of reasonable quality and both interventions failed to control for potential confounders in the analysis. Adverse events and reasons for drop-outs were not reported. There was also no reporting on the costs/benefits of the intervention or how they affected health service utilisation.

Conclusion

This systematic review found limited and inconclusive evidence of the effectiveness of MBSR for PD patients. Both of the included interventions claimed positive effects for PD patients but significant outcomes were often contradicted by other results. Further trials with larger sample sizes, control groups and longer follow-ups are needed before the evidence for MBSR in PD can be conclusively judged.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433018/

Improve Parkinson’s Disease Symptoms with Qigong

February 2, 2017 psyjdc 5 Comments

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Improve Parkinson’s Disease Symptoms with Qigong

By John M. de Castro, Ph.D.

“Through Tai Chi, I get a sense of accomplishment and well being, knowing that I can still function relatively well and, in some cases better, than a person with no physical limitations. It has given me an acute awareness of my body, which parts are not aligned and how to bring them back into the whole of the body so that it functions as one unit. Tai Chi has helped me to cope with Parkinson’s and has heightened my enjoyment of life.” – Daniel Loney

Parkinson’s Disease (PD) has received public attention because of its occurrence in a number of celebrities such as Mohammed Ali, Michael J Fox, and Linda Ronstadt. PD is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech.

Parkinson’s Disease (PD) itself is not fatal but is often associated with related complications which can reduce life expectancy, such as falls, choking, and cardiovascular problems. There are also psychological effects, especially anxiety and depression. All of these symptoms result in a marked reduction in the quality of life. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients. But, since PD is a movement disorder that requires physical therapy for treatment, a mindful movement practice such as Qigong and Tai Chi may be particularly effective. Qigong is ancient mindful movement practices that has been found to produce beneficial effects for a large range of physical and psychological problems. Since, it is a very gentle and safe practice, it is particularly appropriate for the elderly. In addition, falling is the most common cause of injury and death in PD patients and Qigong and Tai Chi have been found to be very effective in lowering the risk of falling. In today’s Research News article “Effects of Health Qigong Exercises on Relieving Symptoms of Parkinson’s Disease.” See:

https://www.facebook.com/ContemplativeStudiesCenter/photos/a.628903887133541.1073741828.627681673922429/1472686966088558/?type=3&theater

or see summary below or view the full text of the study at:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116525/

Liu and colleagues investigate the effectiveness of Qigong practice for the elderly with Parkinson’s Disease (PD). They recruited patients with mild to moderate PD and randomly assigned them to receive either treatment as usual or treatment as usual combined with Qigong practice, 1-hour per day, 5 days per week, for 10 weeks. They were measured for muscle hardness and elasticity, physical stability, and coordination, prior to, during and after the 10-week practice period.

They found that in comparison to treatment as usual, Qigong practice produced a significant (10%) decrease in muscle hardness on both sides at the interim assessment which continued to improve to 20% at the post treatment assessment. The practice also produced a significant 11% improvement in hand eye coordination at interim and 22% at post-test and a significant 30% improvement in balance at interim and 50% at post-test. Hence, Qigong practice produced marked improvements in muscle elasticity, coordination, and balance in PD patients.

These results are striking and clinically significant. Qigong practice would appear to be an important therapy to be used in addition to traditional drug therapy. It should be noted that there was no another exercise condition tested. So, it cannot be determined if any type of gentle exercise would be as effective as Qigong. Regardless, it is clear that Qigong practice helps to ameliorate the motor deterioration produced by Parkinson’s Disease. Since, it is safe, even for use with the frail elderly, it would appear to be an excellent choice for the treatment of PD.

So, improve Parkinson’s disease symptoms with qigong.

“Tai chi engages both mind and body; you might call it “mindful movement.” It may help patients use undamaged parts of their brains to compensate for the areas that normally control automatic movements such as walking.” – Peter Wayne

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts

and on Twitter @MindfulResearch

Study Summary

Liu, X. L., Chen, S., & Wang, Y. (2016). Effects of Health Qigong Exercises on Relieving Symptoms of Parkinson’s Disease. Evidence-Based Complementary and Alternative Medicine : eCAM, 2016, 5935782. http://doi.org/10.1155/2016/5935782

Abstract

The purpose of this study was to investigate the effects of Health Qigong on the treatment and releasing symptoms of Parkinson’s disease (PD). Fifty-four moderate PD patients (N = 54) were randomly divided into experimental and control groups. Twenty-eight PD patients were placed in the experimental group in which the prescribed medication plus Health Qigong exercise will be used as intervention. The other 26 PD patients as the control group were treated only with regular medication. Ten-week intervention had been conducted for the study, and participants completed the scheduled exercises 5 times per week for 60 minutes each time (10 minutes for warm-up, 40 minutes for the exercise, and 10 minutes for cooldown). Data which included the muscle hardness, one-legged blind balance, physical coordination, and stability was collected before, during, and after the intervention. Comparisons were made between the experimental and control groups through the Repeated Measures ANOVA. The results showed that PD patients demonstrate a significant improvement in muscle hardness, the timed “up and go,” balance, and hand-eye coordination (the turn-over-jars test). There were no significant differences between the two groups in gender, age, and course of differences (P < 0.05). The study concluded that Health Qigong exercises could reduce the symptoms of Parkinson’s disease and improve the body functions of PD patients in both the mild and moderate stages. It can be added as an effective treatment of rehabilitation therapy for PD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116525/

Be Mindful with Parkinson’s Disease

October 19, 2016 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“For the person with Parkinson’s, mindfulness might be considered as a method to help with issues of denial and acceptance, loss of independence, and the many frustrations that accompany a disease over which a person has no control and can help him or her feel more connected to body, mind, and spirit in ways that enhance self-understanding and personal insight.”

Parkinson’s Disease (PD) is an incurable progressive degenerative disease of the central nervous system. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications can reduce life expectancy, such as falls, choking, and cardiovascular problems. There are also psychological effects, especially anxiety and depression. All of these symptoms result in a marked reduction in the quality of life. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients. In today’s Research News article “The effects of a mindfulness-based lifestyle program for adults with Parkinson’s disease: a mixed methods, wait list controlled randomised control study.” See:

https://www.facebook.com/ContemplativeStudiesCenter/photos/a.628903887133541.1073741828.627681673922429/1354151734608749/?type=3&theater

or see summary below or view the full text of the study at:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016929/

Advocat and colleagues investigate the effectiveness of mindfulness training on the symptoms of Parkinson’s Disease (PD). They randomly assigned Parkinson’s Disease patients to either receive a modified 6-week, 2-hour per week, mindfulness program or remain with treatment as usual on a wait list. Mindfulness training participants were also provided materials to practice at home. As part of the intervention, they also received education on PD management, stress managements, spirituality, exercise, nutrition, available support, and environmental issues. The participants were measured before and after treatment and 6 months later for PD symptoms, mindfulness, depression, anxiety, locus of control, exercise, and nutrition.

They found that the immediately after the intervention the mindfulness group in comparison to controls had a significant increase in mindfulness and perceived internal locus of control. At the 6-month follow up the mindfulness group had a significant increase in mindfulness, decrease in stress, and an improvement in their diet. On the average, but not significant, were improvements in in Parkinson’s Disease symptoms overall and with activities of daily living.

These results are disappointing and did not replicate previous findings of a positive effect of mindfulness training on PD. The study however, was small, with only 23 patients completing the intervention and thereby did not have sufficient statistical power to detect small differences. The mindfulness training also only lasted for 6-weeks and contained only 5-20 minutes per week of mindfulness training which may have been insufficient to be effective. In addition, follow up measures of adherence to the program were neutral suggesting that the participants were not particularly diligent in their practice. This suggests that future interventions should have a larger number of participants, contain more intensive mindfulness training, and include methods to insure compliance with the practice instructions.

Regardless of these disappointing findings, mindfulness training holds promise to help relieve the suffering of patients with Parkinson’s Disease. It is not a cure and it does not even delay the progression of the disease, but it can be helpful in improving the patient’s quality of life and ability to deal with PD. So, be mindful with parkinson’s disease.

CMCS – Center for Mindfulness and Contemplative Studies

“Long-term mindfulness practitioners increase the working capacity of the brain and connections within the brain, and increase brain matter than non-practitioners. This suggests mindfulness may keep brains young and healthy.“ – Terry Gebhardt

This and other Contemplative Studies posts are available at the Contemplative Studies Blog http://contemplative-studies.org/wp/

They are also available on Google+ https://plus.google.com/106784388191201299496/posts

Study Summary

Advocat, J., Enticott, J., Vandenberg, B., Hassed, C., Hester, J., & Russell, G. (2016). The effects of a mindfulness-based lifestyle program for adults with Parkinson’s disease: a mixed methods, wait list controlled randomised control study. BMC Neurology, 16(1), 166. http://doi.org/10.1186/s12883-016-0685-1

Abstract

Background: Parkinson’s disease (PD) is the second commonest neurodegenerative disease in developed countries. Current treatment for PD is pharmacologically focused and can have significant side-effects. There is increasing interest in holistic approaches including mindfulness to help manage the challenges associated with living with PD. We hypothesised that there would be an improvement in PD associated function and wellbeing in participants after participating in a 6-week mindfulness-based lifestyle program, and that these improvements would be sustainable at 6 months. Our primary objective was to determine changes in function and wellbeing associated with PD.

Methods: An exploratory prospective, mixed-method, randomised control trial incorporating a before and after design with a waitlist control, with an embedded qualitative component was conducted in 2012–2013. Participants included community living adults with disability congruent to H&Y Stage 2 PD, aged 18–75, fluent in spoken and written English and able to attend at least four of six sessions of the program. Participants were randomised to the intervention or wait-list control groups at two locations. All participants in the wait-list control group eventually received the intervention. Two randomisation codes were created for each location. Allocation to the intervention or wait-list control was by random number generation. The program facilitator and participants were blinded to participant data.

Results: Group 1 included 35 participants and group 2 (the waitlist control), 37. Data was analysed from 24 (group 1) and 33 (group 2) participants. The intervention group, compared to the waitlist control, showed a small improvement in function and wellbeing associated with PD immediately after the program (t-score = −0.59) and at 6-month post intervention (t-score = −1.42) as reported by the PDQ-39 SI. However this finding was not significant (p = 0.56 and 0.16 respectively). A small yet significant effect size (β = 0.23) in PDQ-39 ADL was reported in group 1 after 6-months post-intervention. This showed a positive improvement in the ADL as reported by group 1 after 6-months (t-score −1.8, p = 0.04). Four secondary measures are reported.

Conclusions: Our findings suggest mindfulness-based lifestyle programs have potential to assist participants in managing the ongoing difficulties associated with a neurological condition such as Parkinson’s disease. Importantly, our study shows promise for the long term benefits of such programs. Improvements to participant activities in daily living and mindfulness were retained at 6-months post intervention. A more definitive study should be conducted in a larger sample of PD patients to further explore these findings and their impact on reducing stress and anxiety in PD patients.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016929/

Improve Symptoms of Parkinson’s Disease with Mindfulness

May 26, 2016 psyjdc Leave a comment

By John M. de Castro, Ph.D.

“Stress is a primary instigator of symptoms associated with Parkinson’s Disease. A practical and powerful way to reduce stress is to become more mindful which, simply put, means we are present in the moment rather than agonizing over the past or anticipating the future.” – Robert Rodgers

Parkinson’s Disease (PD) has received public attention because of its occurrence in a number of celebrities such as Mohammed Ali, Michael J Fox, and Linda Ronstadt. PD is an incurable disease of the central nervous system that attacks the dopamine neurotransmitter system in the brain. There are around seven million people worldwide and one million people in the U.S. living with PD and about 60,000 people are diagnosed with PD every year. PD is associated with aging as the vast majority of patients are diagnosed after age 50. In fact, it has been speculated that everyone would eventually develop PD if they lived long enough.

PD is an incurable progressive degenerative disease. The condition is caused by the death of nerve cells in the brain that produce the neurotransmitter dopamine. Its physical symptoms include resting tremor, slow movements, muscle rigidity, problems with posture and balance, loss of automatic movements, and slurring of speech. PD itself is not fatal but is often associated with related complications can reduce life expectancy, such as falls, choking, and cardiovascular problems. There are also psychological effects, especially anxiety and depression. All of these symptoms result in a marked reduction in the quality of life.

Mindfulness training has been found to improve the psychological symptoms and the quality of life with PD patients. But, because PD is caused exclusively by a physiological degeneration it would be surprising if mindfulness practice can help improve the physical symptoms. But, in today’s Research News article “Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson’s Disease.” See:

https://www.facebook.com/ContemplativeStudiesCenter/photos/a.628903887133541.1073741828.627681673922429/1236994512991139/?type=3&theater

or below or view the full text of the study at:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842053/

Dissanayaka and colleagues investigated if mindfulness training could improve not only the psychological symptoms and the quality of life but also the physical symptoms of Parkinson’s Disease (PD). They treated PD patients for 8 weeks with a version of the Mindfulness Based Stress Reduction (MBSR) program that was adapted for PD. Measurements of physical and psychological symptoms were obtained before and after treatment and 6 months later.

They found that after mindfulness training there was a significant improvement in anxiety, depression and psychological distress. Cognitive ability also improved including improvements in memory and verbal fluency. These results are compatible with these shown in previous research on mindfulness training for PD patients. These are important effects as they reduce quality of life and can lead to suicidal thoughts. It can be speculated that these effects on psychological well-being were due to the known effects of mindfulness training on emotion regulation. These involve the full experience and recognition of the emotions, but with adaptive responses to them. So, the patients don’t deny how they feel but do not react to them negatively, instead cope with the feelings and act positively.

Of the physical symptoms, they observed improvement in postural instability gait dysfunction but not tremor. This is surprising as these motor symptoms are due to direct deterioration of the neural systems underlying movement. It is possible that the yoga component of MBSR may have improved strength, balance, and flexibility and thereby improved the posture and gait of the PD patients even though the underlying brain degeneration was not affected.

The psychological and motor improvements that were present immediately after mindfulness training were no longer present six months later. But, it should be noted that PD is a progressive disorder, with symptoms getting worse over time, which could have obscured the improvements detected after treatment. The study lacked an untreated control condition, so it is impossible to determine whether the continued deterioration produced the lack of effects at the 6-month follow-up. It should also be noted, however, that the lack of a control condition limits the conclusion that the mindfulness training was responsible for the improvements and not another confounding variable such as a placebo effect or experimenter bias.

Regardless, it is clear that both the psychological and motor symptoms of Parkinson’s Disease can be improve with mindfulness training.

“You would expect mindfulness-based interventions to alleviate the psychological symptoms of Parkinson’s – mindfulness has proved its worth at reducing both anxiety and depression – but a recent study suggests mindfulness training could also address some of the physical changes in the brain. An eight-week course of mindfulness training seemed to increase the density of grey matter in two areas of the brain associated with the disease.” – Plastic Brain

CMCS – Center for Mindfulness and Contemplative Studies

This and other Contemplative Studies posts are available on Google+ https://plus.google.com/106784388191201299496/posts

Study Summary

Dissanayaka, N. N. W., Idu Jion, F., Pachana, N. A., O’Sullivan, J. D., Marsh, R., Byrne, G. J., & Harnett, P. (2016). Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson’s Disease. Parkinson’s Disease, 2016, 7109052. http://doi.org/10.1155/2016/7109052

Abstract

Background. Motor and nonmotor symptoms negatively influence Parkinson’s disease (PD) patients’ quality of life. Mindfulness interventions have been a recent focus in PD. The present study explores effectiveness of a manualized group mindfulness intervention tailored for PD in improving both motor and neuropsychiatric deficits in PD. Methods. Fourteen PD patients completed an 8-week mindfulness intervention that included 6 sessions. The Five Facet Mindfulness Questionnaire (FFMQ), Geriatric Anxiety Inventory, Hamilton Depression Rating Scale, PD Cognitive Rating Scale, Unified PD Rating Scale, PD Quality of Life Questionnaire, and Outcome Questionnaire (OQ-45) were administered before and after the intervention. Participants also completed the FFMQ-15 at each session. Gains at postassessment and at 6-month follow-up were compared to baseline using paired t-tests and Wilcoxon nonparametric tests. Results. A significant increase in FFMQ-Observe subscale, a reduction in anxiety, depression, and OQ-45 symptom distress, an increase in PDCRS-Subcortical scores, and an improvement in postural instability, gait, and rigidity motor symptoms were observed at postassessment. Gains for the PDCRS were sustained at follow-up. Conclusion. The mindfulness intervention tailored for PD is associated with reduced anxiety and depression and improved cognitive and motor functioning. A randomised controlled trial using a large sample of PD patients is warranted.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842053/