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Help Relieve Asthma Symptoms with Yoga

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Help Relieve Asthma Symptoms with Yoga

 

By John M. de Castro, Ph.D.

 

“Yoga can help increase breath and body awareness, slow your respiratory rate, and promote calm and relieve stress — all of which are beneficial for people who have asthma.” – Judi Bar

 

Asthma is a chronic disease of the lungs that involves a persistent inflammation of the airways. When the inflammation worsens, it makes it more difficult for air to move in and out of the lungs provoking coughing, wheezing, shortness of breath and chest tightness. It is estimated that 300 million people worldwide and 30 million people in the U.S. suffer from asthma and the incidence appears to be growing. In the U.S.it is estimated to cost $60 billion per year in healthcare costs and lost productivity. Asthma is the most common chronic disease in the world among children with about 10% of children suffering from asthma.

 

Asthma is not fatal and those with moderate asthma have an equivalent life expectancy to those that don’t. There is no cure for asthma. So, it is a chronic disease that must be coped with throughout the lifetime. Treatments are aimed at symptomatic relief. Most frequently drugs, anti-inflammatory hormones, and inhalers are used to help control the inflammation. Exercise can be difficult with asthma and may actually precipitate an attack. This can be a problem as maintaining fitness with asthma can be difficult. A relatively gentle form of exercise, yoga practice can be practiced without heavy breathing and thus may not provoke asthma. In addition, breathing exercises like those incorporated into yoga practice are known to help control asthma. This suggests that yoga practice may be a helpful exercise for people with asthma.

 

In today’s Research News article “Yoga for asthma.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880926/), Yang and colleagues review, summarize, and perform a meta-analysis of the effectiveness of yoga practice for the treatment of asthma. They found 15 randomized controlled trials (RCTs).

 

They report that the research found that yoga practice produced a significant improvement in the asthma patients’ symptoms, control of asthma, and quality of life and a significant reduction in asthma medication use. In terms of lung function, the research found that yoga practice produced significant improvements in forced vital capacity and peak expiratory flow rate.

 

Hence, yoga practice appears to be beneficial for asthma patients, improving lung function, asthma symptoms, drug use, and improving the patient’s quality of life. There were no recorded adverse events associated with the yoga practice. This is important as exercise is often difficult for asthma patients. Yoga practice appears to be feasible and well tolerated and beneficial for asthma patients.

 

So, help relieve asthma symptoms with yoga.

 

“Having asthma means it can be a struggle to breathe properly, but yoga involves learning how to breathe deeply in and out through the nose to filter the air, and find a natural, balanced breathing pattern. Over time this helps to increase lung capacity and gives you more control of your breathing day-to-day.” – Julia White

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Yang, Z. Y., Zhong, H. B., Mao, C., Yuan, J. Q., Huang, Y. F., Wu, X. Y., … Tang, J. L. (2016). Yoga for asthma. The Cochrane database of systematic reviews, 4(4), CD010346. doi:10.1002/14651858.CD010346.pub2

 

Abstract

Background

Asthma is a common chronic inflammatory disorder affecting about 300 million people worldwide. As a holistic therapy, yoga has the potential to relieve both the physical and psychological suffering of people with asthma, and its popularity has expanded globally. A number of clinical trials have been carried out to evaluate the effects of yoga practice, with inconsistent results.

Objectives

To assess the effects of yoga in people with asthma.

Search methods

We systematically searched the Cochrane Airways Group Register of Trials, which is derived from systematic searches of bibliographic databases including the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, AMED, and PsycINFO, and handsearching of respiratory journals and meeting abstracts. We also searched PEDro. We searched ClinicalTrials.gov and the WHO ICTRP search portal. We searched all databases from their inception to 22 July 2015, and used no restriction on language of publication. We checked the reference lists of eligible studies and relevant review articles for additional studies. We attempted to contact investigators of eligible studies and experts in the field to learn of other published and unpublished studies.

Selection criteria

We included randomised controlled trials (RCTs) that compared yoga with usual care (or no intervention) or sham intervention in people with asthma and reported at least one of the following outcomes: quality of life, asthma symptom score, asthma control, lung function measures, asthma medication usage, and adverse events.

Data collection and analysis

We extracted bibliographic information, characteristics of participants, characteristics of interventions and controls, characteristics of methodology, and results for the outcomes of our interest from eligible studies. For continuous outcomes, we used mean difference (MD) with 95% confidence interval (CI) to denote the treatment effects, if the outcomes were measured by the same scale across studies. Alternatively, if the outcomes were measured by different scales across studies, we used standardised mean difference (SMD) with 95% CI. For dichotomous outcomes, we used risk ratio (RR) with 95% CI to measure the treatment effects. We performed meta‐analysis with Review Manager 5.3. We used the fixed‐effect model to pool the data, unless there was substantial heterogeneity among studies, in which case we used the random‐effects model instead. For outcomes inappropriate or impossible to pool quantitatively, we conducted a descriptive analysis and summarised the findings narratively.

Main results

We included 15 RCTs with a total of 1048 participants. Most of the trials were conducted in India, followed by Europe and the United States. The majority of participants were adults of both sexes with mild to moderate asthma for six months to more than 23 years. Five studies included yoga breathing alone, while the other studies assessed yoga interventions that included breathing, posture, and meditation. Interventions lasted from two weeks to 54 months, for no more than six months in the majority of studies. The risk of bias was low across all domains in one study and unclear or high in at least one domain for the remainder.

There was some evidence that yoga may improve quality of life (MD in Asthma Quality of Life Questionnaire (AQLQ) score per item 0.57 units on a 7‐point scale, 95% CI 0.37 to 0.77; 5 studies; 375 participants), improve symptoms (SMD 0.37, 95% CI 0.09 to 0.65; 3 studies; 243 participants), and reduce medication usage (RR 5.35, 95% CI 1.29 to 22.11; 2 studies) in people with asthma. The MD for AQLQ score exceeded the minimal clinically important difference (MCID) of 0.5, but whether the mean changes exceeded the MCID for asthma symptoms is uncertain due to the lack of an established MCID in the severity scores used in the included studies. The effects of yoga on change from baseline forced expiratory volume in one second (MD 0.04 litres, 95% CI ‐0.10 to 0.19; 7 studies; 340 participants; I2 = 68%) were not statistically significant. Two studies indicated improved asthma control, but due to very significant heterogeneity (I2 = 98%) we did not pool data. No serious adverse events associated with yoga were reported, but the data on this outcome was limited.

Authors’ conclusions

We found moderate‐quality evidence that yoga probably leads to small improvements in quality of life and symptoms in people with asthma. There is more uncertainty about potential adverse effects of yoga and its impact on lung function and medication usage. RCTs with a large sample size and high methodological and reporting quality are needed to confirm the effects of yoga for asthma.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880926/

 

Slow Cellular Aging with Mindfulness

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Slow Cellular Aging with Mindfulness

 

By John M. de Castro, Ph.D.

 

“those with more years of meditation practice had longer telomere length overall, and that women meditators had significantly longer telomeres as compared to women non-meditators. These findings further support meditation’s positive effect on healthy cellular aging.” – Sonima Wellness

 

One of the most exciting findings in molecular biology in recent years was the discovery of the telomere. This is a component of the DNA molecule that is attached to the ends of the strands. Recent genetic research has suggested that the telomere and its regulation is the biological mechanism that produces aging. It has been found that the genes, coded on the DNA molecule, govern cellular processes in our bodies. One of the most fundamental of these processes is cell replication. Cells are constantly turning over. Dying cells or damaged are replaced by new cells. The cells turn over at different rates but most cells in the body are lost and replaced between every few days to every few months. Needless to say, we’re constantly renewing ourselves.

 

As we age the tail of the DNA molecule called the telomere shortens. When it gets very short cells have a more and more difficult time reproducing and become more likely to produce defective cells. On a cellular basis, this is what produces aging. As we get older the new cells produced are more and more likely to be defective. The shortening of the telomere occurs each time the cell is replaced. So, slowly as we age it gets shorter and shorter. This has been called a “mitotic clock.” This is normal. But telomere shortening can also be produced by oxidative stress, which can be produced by psychological and physiological stress. This is mediated by stress hormones and the inflammatory response. So, chronic stress can accelerate the aging process. In other words, when we’re chronically stressed, we get older faster.

 

Fortunately, there is a mechanism to protect the telomere. There is an enzyme in the body called telomerase that helps to prevent shortening of the telomere. It also promotes cell survival and enhances stress-resistance.  Research suggests that processes that increase telomerase activity tend to slow the aging process by protecting the telomere.  One activity that seems to increase telomerase activity and protect telomere length is mindfulness practice. Hence, engaging in mindfulness practices may protect the telomere and thereby slow the aging process.

 

In today’s Research News article “Association among dispositional mindfulness, self-compassion, and leukocyte telomere length in Chinese adults.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647116/), Keng and colleagues recruited adults, aged 18 to 55 years of age, with no regular meditation or mindfulness practice. Blood samples were drawn and leukocyte telomere length measured. In addition, they were measured for mindfulness, self-compassion, anxiety, depression, and stress.

 

They found that, as expected, the older the participant the shorter the telomere length and the higher the levels of perceived stress, the shorter the telomere length. When controlling for age they found that the higher the levels of overall mindfulness and the nonreactivity facet of mindfulness the longer the length of the telomeres. Also, when controlling for age the higher the levels of overall self-compassion and the common humanity and de-identification from one’s thoughts and emotions facets of self-compassion the longer the length of the telomeres.

 

It needs to be kept in mind that these results are correlational and as such causation cannot be determined. However, previous research has demonstrated a causal link by training mindfulness and finding increased telomere lengths. This suggests that the present associations were due to a causal connection between mindfulness and telomere length.

 

In addition, these were young and middle-aged adults who did not display high levels of mindfulness, stress or psychological distress. Mindfulness is thought to affect telomere length as a result of reducing stress which is responsible for shortening the telomers. So, only mild association would be expected. Clearer larger association may require older more distressed participants. The fact that it was the nonreactivity facet of mindfulness that was most strongly associated with longer telomeres supports the contention that stress reduction is the critical effect of mindfulness. By reducing the reaction to events, stress is lowered which, in turn, decreases cellular aging.

 

These results suggest that mindfulness, particularly the nonreactivity facet of mindfulness and self-compassion common humanity and de-identification from one’s thoughts and emotions facets of self-compassion reduces cellular aging. Mindfulness increases self-compassion. So, although not tested here, mindfulness may decrease cellular aging both directly and indirectly via self-compassion. By protecting the telomeres from shortening and mindfulness reduces cellular aging. In this way mindfulness may lead to happier and longer lives.

 

So, slow cellular aging with mindfulness.

 

“one of the most effective interventions, apparently capable of slowing the erosion of telomeres – and perhaps even lengthening them again – is meditation.” – Jo Marchant

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Keng, S. L., Yim, O. S., Lai, P. S., Chew, S. H., & Ebstein, R. P. (2019). Association among dispositional mindfulness, self-compassion, and leukocyte telomere length in Chinese adults. BMC psychology, 7(1), 47. doi:10.1186/s40359-019-0323-y

 

Abstract

Background

Whereas meditation training has been purported to support slower cellular aging, little work has explored the association among different facets of dispositional mindfulness, self-compassion, and cellular aging. The present study aimed to examine the relationship between leukocyte telomere length (LTL), an index of cellular aging, dispositional mindfulness, and self-compassion in a sample of Singaporean Chinese adults.

Methods

One hundred and fifty-eight Chinese adults (mean age = 27.24 years; 63.3% female) were recruited from the community and completed self-report measures assessing dispositional mindfulness, self-compassion, and psychological symptoms, as well as provided blood samples for analyses of LTL. Multiple regression analyses were conducted to examine the role of trait mindfulness and self-compassion in predicting LTL, taking into consideration potential covariates such as chronological age and psychological symptoms.

Results

Results showed that nonreactivity, one of the five facets of dispositional mindfulness, was significantly associated with LTL, after controlling for chronological age. There was also a trend for dispositional mindfulness, self-compassion, and their selected facets (i.e., nonjudging, common humanity, and de-identification) to each be associated with longer LTL.

Conclusions

Overall, the findings provide preliminary support for the association among aspects of dispositional mindfulness, self-compassion, and aging. In particular, individuals high on nonreactivity experience slower aging at the cellular level, likely through engaging in more adaptive coping mechanisms.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647116/

 

Improve the Psychological and Physical Health of Myeloproliferative Neoplasm Patients with a Smartphone Mindfulness App

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Improve the Psychological and Physical Health of Myeloproliferative Neoplasm Patients with a Smartphone Mindfulness App

 

By John M. de Castro, Ph.D.

 

“Even with an app, mindfulness takes practice. Like playing an instrument or a sport, the more you practice, the better you get and the more you get out of it. . . Whatever you try, mindfulness training is considered very safe, and has a good chance of increasing your happiness and peacefulness, and reducing your depression, anxiety, and stress.” – James Cartreine

 

“Myeloproliferative Neoplasms (MPNs) are blood cancers that occur when the body makes too many white or red blood cells, or platelets” (Cancer Support Community). It typically occurs in older adults and is fairly rare (1-2 cases/100,000 per year) and has a very high survival rate. It produces a variety of psychological and physical symptoms including fatigue, anxiety, depression, pain, and sleep disturbance, reduced physical, social, and cognitive functioning resulting in a reduced quality of life.

 

Mindfulness training has been shown through extensive research to be effective in improving physical and psychological health including fatigue, anxiety, depression, pain, and sleep disturbance, and improves physical, social, and cognitive functioning as well as quality of life in cancer patients. The vast majority of the mindfulness training techniques, however, require a trained therapist. This results in costs that many patients can’t afford. In addition, the participants must be available to attend multiple sessions at particular scheduled times that may or may not be compatible with their busy schedules and at locations that may not be convenient.

 

As an alternative, Apps for smartphones have been developed. These have tremendous advantages in decreasing costs, making training schedules much more flexible, and eliminating the need to go repeatedly to specific locations. But the question arises as to the effectiveness of these Apps in relieving the psychological and physical symptoms of cancer and improving their quality of life.

 

In today’s Research News article “Smartphone-Based Meditation for c: Feasibility Study to Inform Future Trials.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658299/), Huberty and colleagues recruited Myeloproliferative Neoplasm Patients and randomly assigned them to either to receive 4 weeks of mindfulness training including 10 minutes of meditation per day via a smartphone app (“Calm”) followed by mindfulness training via another smartphone app (“10% Happier App”), the 2 apps in reverse order, education about Myeloproliferative Neoplasm followed by “10% Happier App”, or education followed by “Calm” app. They were measured before and after training and for Myeloproliferative Neoplasm symptoms, fatigue, anxiety, depression, pain, sleep disturbance, sexual function, health, and quality of life.

 

They found that the participants used the “Calm” App to a significantly greater extent and enjoyed it more than the “10% Happier” App. But following mindfulness training with both apps there were significant improvements. For the “10% Happier” App after training there were significant increases in health, and mental health and decreases in fatigue, anxiety, depression, and sleep disturbance. For the “Calm” App after training there were significant increases in health, and decreases in Myeloproliferative Neoplasm symptoms, fatigue, depression, vaginal discomfort, and sleep disturbance.

 

This was a relatively small pilot study that demonstrated the feasibility and efficacy of mindfulness training smartphone apps for the treatment of Myeloproliferative Neoplasm patients. It would appear that the “Calm” App is the preferred app. But both were effective in producing benefits. The improvements were significant and helpful in relieving the suffering of the patients. This is important as the use of smartphone apps makes it easier, more convenient, and more cost effective to provide mindfulness training to a wide swath of Myeloproliferative Neoplasm patients thus maximizing the utilization of mindfulness training for the improvement of the symptoms of patients with Myeloproliferative Neoplasm.

 

So, improve the psychological and physical health of myeloproliferative neoplasm patients with a smartphone mindfulness app.

 

“So how can this practice of mindfulness help people with cancer? . . . Routinely, we see large and meaningful improvements in mood, stress levels, depression, anger, worry, and rumination. We also see people having an increased sense of meaning and purpose in life, better sleep, and more energy, as well as displaying biological changes like a healthier pattern of stress hormones and less inflammation in the immune system.” – Linda Carlson

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Jennifer Huberty, Ryan Eckert, Linda Larkey, Jonathan Kurka, Sue A Rodríguez De Jesús, Wonsuk Yoo, Ruben Mesa. Smartphone-Based Meditation for Myeloproliferative Neoplasm Patients: Feasibility Study to Inform Future Trials. JMIR Form Res. 2019 Apr-Jun; 3(2): e12662. Published online 2019 Apr 29. doi: 10.2196/12662

 

 

Abstract

Background

Myeloproliferative neoplasm (MPN) patients often report high symptom burden that persists despite the best available pharmacologic therapy. Meditation has gained popularity in recent decades as a way to manage cancer patient symptoms.

Objective

The aim of this study was to examine the feasibility of 2 different consumer-based meditation smartphone apps in MPN patients and to examine the limited efficacy of smartphone-based meditation on symptoms compared with an educational control group.

Methods

Patients (n=128) were recruited nationally through organizational partners and social media. Eligible and consented patients were enrolled into 1 of 4 groups, 2 of which received varying orders of 2 consumer-based apps (10% Happier and Calm) and 2 that received one of the apps alone for the second 4 weeks of the 8-week intervention after an educational control condition. Participants were asked to perform 10 min of meditation per day irrespective of the app and the order in which they received the apps. Feasibility outcomes were measured at weeks 5 and 9 with a Web-based survey. Feasibility outcomes were acceptability, demand, and limited efficacy for depression, anxiety, pain intensity, sleep disturbance, sexual function, quality of life, global health, and total symptom burden.

Results

A total of 128 patients were enrolled across all 4 groups, with 73.4% (94/128) patients completing the intervention. Of the participants who completed the 10% Happier app, 61% (46/76) enjoyed it, 66% (50/76) were satisfied with the content, and 77% (59/76) would recommend to others. Of those who completed the Calm app, 83% (56/68) enjoyed it, 84% (57/68) were satisfied with the content, and 97% (66/68) would recommend to others. Of those who completed the educational control, 91% (56/61) read it, 87% (53/61) enjoyed it, and 71% (43/61) learned something. Participants who completed the 10% Happierapp averaged 31 (SD 33) min/week; patients completing the Calm app averaged 71 (SD 74) min/week. 10% Happier app participants saw small effects on anxiety (P<.001 d=−0.43), depression (P=.02; d=−0.38), sleep disturbance (P=.01; d=−0.40), total symptom burden (P=.13; d=−0.27), and fatigue (P=.06; d=−0.30), and moderate effects on physical health (P<.001; d=0.52). Calm app participants saw small effects on anxiety (P=.29; d=−0.22), depression (P=.09; d=−0.29), sleep disturbance (P=.002; d=−0.47), physical health (P=.005; d=0.44), total symptom burden (P=.13; d=−0.27), and fatigue (P=.13; d=−0.27). Educational control participants (n=61) did not have effects on any patient-reported outcome except for a moderate effect on physical health (P<.001; d=0.77).

Conclusions

Delivering meditation via the Calm app is feasible and scored higher in terms of feasibility when compared with the 10% Happier app. The Calm app will be used to implement a randomized controlled trial, testing the effects of meditation on symptom burden in MPNs.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658299/

Sexual Arousal and Mindfulness are Linked in Complex Ways

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Sexual Arousal and Mindfulness are Linked in Complex Ways

 

By John M. de Castro, Ph.D.

 

“mindfulness meditation” training — which teaches how to bring one’s thoughts into the present moment — can quiet the mental chatter that prevents these women from fully feeling sexual stimuli.” – Gina Silverstein

 

Problems with sex are very common, but, with the exception of male erectile dysfunction, driven by the pharmaceutical industry, it is rarely discussed and there is little research. While research suggests that sexual dysfunction is common, it is a topic that many people are hesitant or embarrassed to discuss. Women suffer from sexual dysfunction more than men with 43% of women and 31% of men reporting some degree of difficulty. These problems have major impacts on people’s lives and deserve greater research attention.

 

Problems with sex with women can involve reduced sex drive, difficulty becoming aroused, vaginal dryness, lack of orgasm and decreased sexual satisfaction. Sexual function in women involves many different systems in the body, including physical, psychological and hormonal factors. So, although, female sexual dysfunction is often caused by physical/medical problems, it is also frequently due to psychological issues. This implies that it many cases female sexual problems may be treated with therapies that are effective in working with psychological problems.

 

Mindfulness trainings have been shown to improve a variety of psychological issues including emotion regulation, stress responses, trauma, fear and worry, anxiety, and depression, and self-esteem. Mindfulness training has also been found useful in treating sexual problems. But there is little empirical research. So, it makes sense to further investigate the relationship of mindfulness with female sexual arousal.

 

In today’s Research News article “Subjective and Oxytocinergic Responses to Mindfulness Are Associated With Subjective and Oxytocinergic Responses to Sexual Arousal.” (See summary below or view the full text of the study at: https://www.frontiersin.org/articles/10.3389/fpsyg.2019.01101/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_999212_69_Psycho_20190528_arts_A), Dickinson and colleagues recruited women between the ages of 20 to 35 for a study on sexuality and stress hormones and measured them for mindfulness. They watched landscape photographs and rated their liking of the photographs and then provided salivary samples to assess oxytocin and cortisol. Oxytocin levels are a marker of sexual arousal. They then listened to 1.5-minute stories that were either neutral or erotic and provided salivary samples. They also rated their sexual arousal after each story. They then performed a breath focused meditation for 15 minutes and provided a third salivary sample. After a 15-minute quiet period they provided a fourth sample.

 

They found that the higher the women scored on mindfulness, particularly the describing facet, the higher their levels of reported arousal in response to the erotic stories. They also found that oxytocin levels did not significantly increase in response to the erotic stories, decreased significantly in response to mindful breathing, and increased during recovery. They further found that women high in the mindfulness facet of non-judging internal experience and women who were quicker in detecting mind wandering during meditation had significantly greater decreases in oxytocin during meditation. In addition, women who were quick in detecting mind wandering and women who reported large increases in sexual arousal while listening to the erotic stories had greater decreases in oxytocin while meditating.

 

These are complex results. They suggest that in women mindfulness, subjective sexual arousal, and endocrine markers of sexual arousal are all linked in complex ways. They also suggest that women who are high in mindfulness are more sexually responsive to erotic stimuli. This may suggest that mindfulness training may be effective in increasing women’s ability to be sexually aroused. Future research should investigate whether mindfulness training may be an effective treatment for women who have difficulty with sexual arousal.

 

“among women who have sexual difficulties, mindfulness not only improves their desire but improves their overall sexual satisfaction, too.” – Tracy Clark-Flory

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Dickenson JA, Alley J and Diamond LM (2019) Subjective and Oxytocinergic Responses to Mindfulness Are Associated With Subjective and Oxytocinergic Responses to Sexual Arousal. Front. Psychol. 10:1101. doi: 10.3389/fpsyg.2019.01101

 

Mindfulness – the ability to pay attention, on purpose, without judgment, and in the present moment – has consistently been shown to enhance women’s sexual arousal. As a first step toward understanding potential neuroendocrine underpinnings of mindfulness and sexual arousal, we examined whether individual differences in subjective and neuroendocrine (i.e., oxytocin) responses to mindful breathing were associated with individual differences in subjective and neuroendocrine responses to sexual arousal. To achieve this aim, 61 lesbian, bisexual, and heterosexual women completed a questionnaire assessing dispositional mindfulness, underwent an arousal task while continuously rating their sexual arousal and a mindful breathing task, after which participants reported on their ability to detect attentional shifts, and provided salivary samples after each assessment. Results indicated that women who were quicker to detect attentional shifts and women who reported greater sexual arousability reported larger changes (decreases) in oxytocin in response to mindful breathing and were the only women to report increases in oxytocin in response to the sexual arousal induction. Results further indicated that individuals who report greater subjective responsiveness to mindfulness and sexual arousal appear to have an oxytocinergic system that is also more responsive to both arousal and to mindfulness. These results make a significant contribution to our understanding of the role of attentional processes in sexual arousal, and warrant future examination of oxytocin as a potential neuroendocrine mechanism underlying the link between mindfulness and sexual arousal.

https://www.frontiersin.org/articles/10.3389/fpsyg.2019.01101/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_999212_69_Psycho_20190528_arts_A

 

Improve Cancer-Related Symptoms in Cancer Survivors with Tai Chi

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Improve Cancer-Related Symptoms in Cancer Survivors with Tai Chi

 

By John M. de Castro, Ph.D.

 

“In terms of the evidence that’s out there and the scientific literature, practices such as tai chi have been found to help improve patients’ quality of life. There are some studies showing that these types of mind-body practices can also have an impact on physiological functioning, improving aspects of immune function and decreasing stress hormones.” – Lorenzo Cohen

 

Receiving a diagnosis of cancer has a huge impact on most people. Coping with the emotions and stress of a cancer diagnosis is a challenge and there are no simple treatments for these psychological sequelae of cancer diagnosis. But cancer diagnosis is not necessarily a death sentence. Over half of the people diagnosed with cancer are still alive 10 years later and this number is rapidly increasing. It is estimated that 15 million adults and children with a history of cancer are alive in the United States today. But, surviving cancer carries with it a number of problems. “Physical, emotional, and financial hardships often persist for years after diagnosis and treatment. Cancer survivors are also at greater risk for developing second cancers and other health conditions.” National Cancer Survivors Day.

 

Mindfulness training has been shown to help with cancer recovery and help to alleviate many of the residual physical and psychological symptoms, including stress,  sleep disturbance, and anxiety and depression. Tai Chi or Qigong practice has been shown to improve quality of life, reduce fatigue, and lower blood pressure and cortisol levels. They are very gentle and safe practices. The research is accumulating. So, it makes sense to take a step back and summarize what has been found in regard to Tai Chi practice for the treatment of cancer survivors.

 

In today’s Research News article “Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958892/), Wayne and colleagues review, summarize, and perform a meta-analysis of the effectiveness of Tai Chi practice in relieving cancer-related symptoms in cancer survivors. They identified 22 published research studies that included a total of 1571 cancer survivors. 15 of the studies were randomized controlled trials investigating survivors of a variety of cancers including breast, prostate lymphoma, lung, and multiple cancers.

 

They report that in general the research studies demonstrated a significant reduction in fatigue, sleep difficulty, depression , and quality of life resulting from Tai Chi practice. No significant improvements in pain were observed. No adverse events were reported. Hence, the research suggests that Tai Chi practice is a safe and effective treatment for cancer-related symptoms in cancer survivors. Tai Chi practice appears to benefit the mental and physical health of the survivors.

 

The results of the published research strongly suggests that Tai Chi  practice should be routinely prescribed for survivors of cancer. Tai Chi is a gentle and safe mindfulness practice. It is appropriate for all ages including the elderly and for individuals with illnesses that limit their activities or range of motion. It is inexpensive to administer, can be performed in groups or alone, at home or in a facility, and can be quickly learned. In addition, it can be practiced in social groups. This can make it fun, improving the likelihood of long-term engagement in the practice. So, Tai Chi practice would appear to be an excellent gentle practice to improve the well-being of cancer survivors.

 

So, improve cancer-related symptoms in cancer survivors with Tai Chi.

 

“Tai chi does not treat the cancer itself. Research suggests that tai chi can help lower blood pressure, reduce stress, ease pain and stiffness and improve sleep. Small studies have shown that regular tai chi may help with depression and improve self-esteem. These studies have also suggested that regular practice of tai chi can improve quality of life.” – Canadian Cancer Society

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Wayne, P. M., Lee, M. S., Novakowski, J., Osypiuk, K., Ligibel, J., Carlson, L. E., & Song, R. (2017). Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis. Journal of cancer survivorship : research and practice, 12(2), 256–267. doi:10.1007/s11764-017-0665-5

 

Abstract

Purpose

Summarize and critically evaluate the effects of Tai Chi and Qigong (TCQ) mind-body exercises on symptoms and quality of life (QOL) in cancer survivors.

Methods

A systematic search in 4 electronic databases targeted randomized and non-randomized clinical studies evaluating TCQ for fatigue, sleep difficulty, depression, pain, and quality of life (QOL) in cancer patients, published through August 2016. Meta-analysis was used to estimate effect sizes (ES, Hedges’ g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed.

Results

Our search identified 22 studies, including 15 RCTs that evaluated 1283 participants in total, 75% women. RCTs evaluated breast (n=7), prostate (n=2), lymphoma (n=1), lung (n=1), or combined (n=4) cancers. RCT comparison groups included active intervention (n=7), usual care (n=5), or both (n=3). Duration of TCQ training ranged from 3 to 12 weeks. Methodological bias was low in 12 studies and high in 3 studies. TCQ was associated with significant improvement in fatigue [ES=−0.53, p<.001], sleep difficulty [ES=−0.49, p=.018], depression [ES=−0.27, p=.001], and overall QOL [ES=0.33, p=.004]; a statistically non-significant trend was observed for pain [ES=−0.38, p=.136]. Random effects models were used for meta-analysis based on Q-test and I-squared criteria. Funnel plots suggest some degree of publication bias. Findings in non-randomized studies largely paralleled meta-analysis results.

Conclusions

Larger and methodologically sound trials with longer follow-up periods and appropriate comparison groups are needed before definitive conclusions can be drawn, and cancer- and symptom-specific recommendations can be made.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958892/

 

Reduce Painful Diabetic Neuropathy with Mindfulness

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Reduce Painful Diabetic Neuropathy with Mindfulness

 

By John M. de Castro, Ph.D.

 

“Meditation techniques can help people struggling with neuropathy symptoms live through their pain. It can help to lower stress, improve your coping skills, and decrease your pain intensity. Taking a mind-body approach is a noninvasive technique that provides you with more control over your condition.” – Healthline

 

Managing Diabetes can be difficult on the health and quality of life of the patient. In addition, Diabetes can lead to a very painful condition known as diabetic neuropathy. The high blood glucose levels associated with diabetes can damage nerves and result in a burning pain and numbness, particularly from the legs and feet. It affects the majority of long-term diabetes patients. This is not only painful but is also disruptive to the normal life functions of these patients. There are no cures, but diabetic neuropathy can be prevented by blood glucose control in the diabetic patient with a rigorous program of measured diet and exercise. Treatment for diabetic neuropathy usually involves pain management with drugs.

 

Mindfulness practices have been shown to help with pain management and with quality of life in diabetes patients. It is possible, then, that mindfulness practices may be effective in reducing pain and improving quality of life in patients with diabetic neuropathy. In today’s Research News article “Randomized Trial of the Effect of Mindfulness-Based Stress Reduction on Pain-Related Disability, Pain Intensity, Health-Related Quality of Life, and A1C in Patients With Painful Diabetic Peripheral Neuropathy.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734176/ ), Nathan and colleagues examined the effectiveness of mindfulness training on reducing pain and improving the quality of life in patients with Painful diabetic peripheral neuropathy (PDPN).

 

They recruited adults with Type II Diabetes and with Painful diabetic peripheral neuropathy (PDPN). The participants were maintained on their usual pharmacological treatments and randomly assigned to a wait-list or to receive an additional 8-week program, once weekly 2.5 hour sessions and home practice, of Mindfulness-Based Stress Reduction (MBSR). The mindfulness program consists of group discussion and training in sitting, walking, and body scan meditations, and yoga practice. They were measured before and after training and 3 months later for pain related disability, pain severity, pain catastrophizing, health related and diabetic neuropathy related quality of life, depression, diabetes self-care, blood sugar reactions, and A1C levels, a measure of long-term blood glucose control.

 

They found that in comparison to baseline and the wait-list control, the participants who received Mindfulness-Based Stress Reduction (MBSR) training had significantly improved scores on all measures including lower pain related disability, pain severity, pain catastrophizing, depression health related and diabetic neuropathy related quality of life, diabetes self-care, blood sugar reactions, and A1C levels. These improvements were maintained at the 3-month follow-up. In addition, there was a high retention rate with 94% of the treated patients completing the 8-week training and the 3-month follow-up.

 

These results are striking and important. Diabetic Neuropathy is a torment for Type II Diabetes patients and mindfulness training was found to markedly improve this condition. It increased quality of life and health and decreased pain and pain associated psychological and physical difficulties. This relief of suffering in important and remarkable and should lead to a recommendation for mindfulness training to be included in the usual care of patients with Painful diabetic peripheral neuropathy (PDPN).

 

So, reduce painful diabetic neuropathy with mindfulness.

 

“When people with diabetes are more mindful – being calmly aware of what is going on around them, inside their bodies and in their minds – they can potentially make healthier lifestyle choices, such as diet, medication and exercise, that help lower their blood glucose. Additionally, stress reduction decreases the amount of stress hormones, such as cortisol, in the blood. When elevated for too long, cortisol can cause anxiety, depression, digestive problems, heart disease, sleep problems, weight gain and memory and concentration problems.” – Diabetes Canada

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Nathan, H. J., Poulin, P., Wozny, D., Taljaard, M., Smyth, C., Gilron, I., Sorisky, A., Lochnan, H., … Shergill, Y. (2017). Randomized Trial of the Effect of Mindfulness-Based Stress Reduction on Pain-Related Disability, Pain Intensity, Health-Related Quality of Life, and A1C in Patients With Painful Diabetic Peripheral Neuropathy. Clinical diabetes : a publication of the American Diabetes Association, 35(5), 294-304.

 

Abstract

IN BRIEF Painful diabetic peripheral neuropathy (PDPN) has a large negative impact on patients’ physical and mental functioning, and pharmacological therapies rarely provide more than partial relief. Mindfulness-based stress reduction (MBSR) is a group psychosocial intervention that was developed for patients with chronic illness who were not responding to existing medical treatments. This study tested the effects of community-based MBSR courses for patients with PDPN. Among patients whose PDPN pharmacotherapy had been optimized in a chronic pain clinic, those randomly assigned to treatment with MBSR experienced improved function, better health-related quality of life, and reduced pain intensity, pain catastrophizing, and depression compared to those receiving usual care.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734176/

 

Improve Glaucoma with Meditation

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Improve Glaucoma with Meditation

 

By John M. de Castro, Ph.D.

 

“a relaxation program with meditation can lower IOP (intraocular pressure) in glaucoma patients and improve their quality of life by lowering stress hormones like cortisol.” – Tanuj Dada

 

Glaucoma is a disease of the eye that is the leading cause of blindness in people over 60 years of age, although it can occur at younger ages. It affects over 65 million people worldwide and over 3 million Americans. It involves an abnormally high pressure in the eye that if untreated produces permanent damage to the retina and the optic nerve. It often occurs without other symptoms and can only be detected with measurement of intraocular pressure. Treatments are designed to prevent further damage by lowering intraocular pressure and may involve eyedrops, drugs, laser treatment or surgery. “These therapies are costly and have ocular and systemic side effects that can adversely affect the health-related quality of life of glaucoma patients.”

 

Mindfulness training is known to be able to lower blood pressure. So, it is possible that meditation practice may be useful in the treatment of glaucoma. In today’s Research News article “Mindfulness Meditation Reduces Intraocular Pressure, Lowers Stress Biomarkers and Modulates Gene Expression in Glaucoma: A Randomized Controlled Trial.” (See summary below or view the full text of the study at: https://eyewire.news/articles/study-meditation-an-effective-therapy-to-reduce-eye-pressure-in-primary-open-angle-glaucoma/), Dada and colleagues recruited patients with open-angle Glaucoma who were being treated with prescription eye drops and randomly assigned them to either receive a 3 week, once a day for 60 minutes, program of meditation and yogic breathing exercises or to a wait-list control condition. They were measured before and after treatment for intraocular pressure, quality of life, stress-related serum biomarkers [cortisol, β-endorphins, IL6, TNF-α, brain-derived neurotrophic factor, reactive oxygen species, total antioxidant capacity], and whole genome expression.

 

They found that in comparison to baseline and the wait-list control that the Glaucoma patients who meditated had significantly lower intraocular pressure and stress-related serum biomarkers and significantly improved quality of life.  Additionally, meditation significantly reduced the levels of the stress hormone, cortisol levels and increased the levels of beta-endorphins and brain-derived neurotrophic factors and reduced the levels of the pro-inflammatory markers, interleukins. In addition, the greater the decrease in intraocular pressure the greater the improvements in quality of life and the stress-related serum biomarkers. These changes correlated well with gene expression profiling.

 

These are exciting results that suggest that meditation may be a safe and effective treatment for Glaucoma. The reduction in intraocular pressure may reduce further damage to the optic nerve and help to preserve the remaining vision of the patients. Further the reduction in stress hormones and inflammation suggests an overall improvement in the patient’s health.

 

Meditation appears to produce these benefits by reducing the physiological responses to stress. This makes sense as stress has been shown to be highly related to the development of Glaucoma and mindfulness practices are well known to reduce the physiological and psychological responses to stress. The authors speculate that the relaxation produced by meditation and yogic breathing exercises is responsible for the benefits. Regardless of the mechanism, the findings indicate that meditation practice may be a treatment to slow further visual degeneration and improve the lives of Glaucoma sufferers,

 

So, improve glaucoma with meditation.

 

“When scientists asked 45 glaucoma patients to try mindfulness meditation for an hour a day for three weeks they discovered that the pressure in their eyes lowered by 25 per cent  compared to patients who stuck to eye drops.” Sarah Knapton

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Dada, Tanuj, Mittal, Deepti, Mohanty, Kuldeep, Faiq, Muneeb A., Bhat, Muzaffer A., Yadav, Raj K., Sihota, Ramanjit, Sidhu, Talvir, Velpandian, Thirumurthy, Kalaivani, Mani, Pandey, Ravindra M., Gao, Ying, Sabel, Bernhard A., Dada, Rima. Mindfulness Meditation Reduces Intraocular Pressure, Lowers Stress Biomarkers and Modulates Gene Expression in Glaucoma: A Randomized Controlled Trial. Journal of Glaucoma: December 2018 – Volume 27 – Issue 12 – p 1061–1067. doi: 10.1097/IJG.0000000000001088

 

Background: Reducing intraocular pressure (IOP) in primary open-angle glaucoma (POAG) is currently the only approach to prevent further optic nerve head damage. However, other mechanisms such as ischemia, oxidative stress, glutamate excitotoxicity, neurotrophin loss, inflammation/glial activation, and vascular dysregulation are not addressed. Because stress is a key risk factor affecting these mechanisms, we evaluated whether mindfulness-based stress reduction can lower IOP and normalize typical stress biomarkers.

Materials and Methods: In a prospective, randomized trial 90 POAG patients (180 eyes; age above 45 y) were assigned to a waitlist control or mindfulness meditation group which practiced daily for 21 days. We measured IOP (primary endpoint), quality of life (QOL), stress-related serum biomarkers [cortisol, β-endorphins, IL6, TNF-α, brain-derived neurotrophic factor (BDNF), reactive oxygen species (ROS), total antioxidant capacity (TAC)], and whole genome expression.

Results: Between-group comparisons revealed significantly lowered IOP in meditators (OD: 18.8 to 12.7, OS 19.0 to 13.1 mm Hg) which correlated with significantly lowered stress-biomarker levels including cortisol (497.3 to 392.3 ng/mL), IL6 (2.8 to 1.5 ng/mL), TNF-α (57.1 to 45.4 pg/mL), ROS (1625 to 987 RLU/min/104 neutrophils), and elevated β-endorphins (38.4 to 52.7 pg/mL), BDNF (56.1 to 83.9 ng/mL), and TAC (5.9 to 9.3) (all P<0.001). These changes correlated well with gene expression profiling. Meditators improved in QOL (P<0.05).

Conclusions: A short course of mindfulness-based stress reduction by meditation in POAG, reduces IOP, improves QOL, normalizes stress biomarkers, and positively modifies gene expression. Mindfulness meditation can be recommended as adjunctive therapy for POAG.

https://eyewire.news/articles/study-meditation-an-effective-therapy-to-reduce-eye-pressure-in-primary-open-angle-glaucoma/

 

Improve Type 2 Diabetes with Yoga Practice

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Improve Type 2 Diabetes with Yoga Practice

 

By John M. de Castro, Ph.D.

 

“Yoga can do more than just relax your body in mind — especially if you’re living with diabetes. Certain poses may help lower blood pressure and blood sugar levels while also improving circulation, leading many experts to recommend yoga for diabetes management.” – HealthLine

 

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes and the numbers are growing. Type II Diabetes results from a resistance of tissues, especially fat tissues, to the ability of insulin to promote the uptake of glucose from the blood. As a result, blood sugar levels rise producing hyperglycemia. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

 

Type 2 diabetes is a common and increasingly prevalent illness that is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary life style. Unlike Type I Diabetes, Type II does not require insulin injections. Instead, the treatment and prevention of Type 2 Diabetes focuses on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. A mindfulness practice that combines mindfulness with exercise is yoga and it has been shown to be helpful in the treatment of Type II Diabetes.

 

In today’s Research News article “Therapeutic Role of Yoga in Type 2 Diabetes.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145966/ ), Raveendran and colleagues review and summarize the published research studies of the effectiveness of yoga practice for the treatment of Type 2 diabetes. They report that the research suggests that yoga practice produces beneficial changes in the behavior, psychology, and physiology of patients with Type 2 diabetes.

 

People with Type 2 diabetes who practice yoga have been shown to improve their diets, engage in greater levels of exercise, and develop greater tolerance for exercise. This is important as improved diet and greater exercise have been shown to improve Type 2 diabetes. The practitioners also feel better psychologically, with improved mood, greater quality of life and reduced perceived stress levels.

 

On the physiological level people with Type 2 diabetes who practice yoga show reductions in body weight which is important for reducing insulin resistance. They have improved cardiovascular function, including reduced heart rate and blood pressure and improved blood fat profiles. Yoga practice with diabetes has also been shown to strengthen the immune system, reduce stress hormones, and reduce the inflammatory response. Practitioners also show autonomic nervous system changes including increased parasympathetic and reduce sympathetic activity, producing enhanced physiological relaxation. Finally, yoga practice has been shown to increase insulin secretion and reduce insulin resistance.

 

The studies, though, are often of weak research design either lacking in a control condition or not having an active control condition for appropriate comparison and with weak statistical analysis. The studies are often of short duration without follow-up measures to verify the longevity of the benefits. There are also present uncontrolled confounding factors such as selection bias, subject expectancy effects, and experimenter bias effects. Hence, the research is encouraging, but not definitive that yoga practice is greatly beneficial for the treatment of Type 2 Diabetes. More and better research is needed.

 

So, improve Type 2 Diabetes with yoga practice.

 

“I recommend yoga primarily for stress management. Stress elevates blood sugar, which can lead to more diabetes complications. Yoga helps us center ourselves, and centering calms us and can help keep blood sugar levels balanced.” – Janet Zappe

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

Raveendran, A. V., Deshpandae, A., & Joshi, S. R. (2018). Therapeutic Role of Yoga in Type 2 Diabetes. Endocrinology and metabolism (Seoul, Korea), 33(3), 307-317.

 

Abstract

Yoga originated in India more than 5,000 years ago and is a means of balancing and harmonizing the body, mind, and emotions. Yoga practice is useful in the management of various lifestyle diseases, including type 2 diabetes. Psycho-neuro-endocrine and immune mechanisms are involved in the beneficial effects of yoga on diabetes. Incorporation of yoga practice in daily life helps to attain glycaemic control and reduces the risk of complications in people with diabetes. In this review, we briefly describe the role of various yoga practices in the management of diabetes based on evidence from various clinical studies.

 

CONCLUSIONS

Yoga therapy is relevant for wellness, as well as for illness. The latest scientific evidence suggests the potential role of yoga-based lifestyle modifications in the management of type 2 diabetes and its associated risk factors. It is suggested that psychoneuro-endocrine and immune mechanisms have holistic effects in diabetes control. Parasympathetic activation and the associated anti-stress mechanisms improve patients’ overall metabolic and psychological profiles, increase insulin sensitivity, and improve glucose tolerance and lipid metabolism. Yoga practices such as cleansing processes, asanas, pranayama, mudras, bandha, meditation, mindfulness, and relaxation are known to reduce blood glucose levels and to help in the management of comorbid disease conditions associated with type 2 diabetes mellitus, resulting in significant positive clinical outcomes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145966/

 

Improve Obesity with Metabolic Syndrome with Yoga Practice

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Improve Obesity with Metabolic Syndrome with Yoga Practice

 

By John M. de Castro, Ph.D.

 

“I think yoga can be a wonderful form of movement that bigger-bodied people can adapt for themselves.” For folks carrying more weight, low-impact exercises like yoga may be more comfortable than, say, running on the pavement. And most postures can be modified to fit your body. Plus, yoga isn’t that cycling class with the drill sergeant instructor. The mental component of yoga—the deep breathing, positive meditation and awareness—can boost confidence for people of all waistlines. “Yoga helps give you insight, and perhaps that insight can help you make better choices and eliminate negative self-talk,” – Laura McMullen

 

Obesity has become an epidemic in the industrialized world. In the U.S. the incidence of obesity, has more than doubled over the last 35 years to currently around 35% of the population, while two thirds of the population are considered overweight or obese (Body Mass Index; BMI > 25). Obesity has been found to shorten life expectancy by eight years and extreme obesity by 14 years. This occurs because obesity is associated with cardiovascular problems such as coronary heart disease and hypertension, stroke, metabolic syndrome, diabetes, cancer, arthritis, and others.

 

Metabolic Syndrome is a major risk factor for cardiovascular disease and diabetes. It generally results from overweight and abdominal obesity and includes high blood pressure, insulin resistance and elevation of plasma cholesterol and triglycerides. It is highly associated with obesity and type-2 diabetes. Metabolic Syndrome incidence has been rising rapidly and it currently affects 34% of U.S. adults. The simplest treatment is simply exercise and weight loss. Also, mindfulness techniques have been shown to be effective in treating Metabolic Syndrome.

 

Obviously, there is a need for effective treatments to prevent or treat obesity and metabolic syndrome. But, despite copious research and a myriad of dietary and exercise programs, there still is no safe and effective treatment. Mindfulness is known to be associated with lower risk for obesity, alter eating behavior and improve health in obesity. Yoga practice has been shown to have a myriad of physical and psychological benefits. These include significant loss in weight and body mass index (BMI), resting metabolism, and body fat in obese women with Type 2 diabetes and improve health in the obese. In addition, it has the added benefit of being a gentle exercise. Hence it would seem reasonable to further investigate the benefits of yoga practice on the weight and body composition of the obese with metabolic syndrome.

 

In today’s Research News article “One Year of Yoga Training Alters Ghrelin Axis in Centrally Obese Adults With Metabolic Syndrome.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158302/ ), Yu and colleagues studied the effects of 1-year of yoga practice on the metabolic hormones that are involved in body weight and metabolism. They selected from a previous study yoga trained and control participants who were obese and were diagnosed with metabolic syndrome. Hatha yoga practice occurred for 1 hour, 3 times per week for 1 year. They were measured before and after training for waist circumference, blood pressure, heart rate, physical performance, and blood levels of glucose, triglycerides, high-density lipoprotein, and cholesterol. In addition, the blood was assayed for peptides including insulin, markers of insulin resistance, ghrelin, obestatin, and growth hormone.

 

They found that the yoga group had a significantly greater decrease in waist circumference, 4%, compared to controls who had a 2% increase in waist circumference. The yoga group also had significantly greater improvements in resting heart rate and physical performance than the control group. Hence, yoga practice improves body size, physical ability and cardiovascular function in obese individuals with metabolic syndrome.

 

In addition, yoga training produced significantly greater decrease in the peptide obestatin and increases in growth hormone and ghrelin. High levels of obestatin and low levels of ghrelin and growth hormone have been found to be associated with obesity and metabolic syndrome. Hence, yoga practice produced a trend toward normalization of these hormones associated with obesity and metabolic syndrome.

 

These results suggest that yoga practice is beneficial for people with obesity and metabolic syndrome, improving their body size, and physical performance, and tending to normalize their metabolic hormonal state. This further suggests that practicing yoga may reduce risk factors and improve the long-term health of the obese with metabolic syndrome. Future research should compare the effectiveness of yoga practice to other exercise programs.

 

So, improve obesity with metabolic syndrome with yoga practice.

 

 “Yoga is a powerful activity that connects mind, body and a sense of self to achieve endless health benefits, including maintaining weight-loss. The philosophy of yoga fosters a healing practice that brings peace and acceptance to the self no matter where you are in your life. There are no prerequisites for yoga. You are not required to look a certain way, fold yourself into a tricky asana (pose), or even be at a certain level of flexibility.” – Laurel Dierking

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Yu, A. P., Ugwu, F. N., Tam, B. T., Lee, P. H., Lai, C. W., Wong, C., Lam, W. W., Sheridan, S., … Siu, P. M. (2018). One Year of Yoga Training Alters Ghrelin Axis in Centrally Obese Adults With Metabolic Syndrome. Frontiers in physiology, 9, 1321. doi:10.3389/fphys.2018.01321

 

Abstract

Introduction: Metabolic syndrome (MetS) is a multiplex cardiometabolic manifestation associated with type 2 diabetes mellitus and cardiovascular diseases. Yoga training has been shown to alleviate MetS. Recently, circulatory ghrelin profile was demonstrated to be associated with MetS. This study examined the effects of 1 year of yoga training on β-cell function and insulin resistance, and the involvement of metabolic peptides, including unacylated ghrelin (UnAG), acylated ghrelin (AG), obestatin, growth hormone (GH), and insulin, in the beneficial effects of yoga training in centrally obese adults with MetS.

Methods: This was a follow up study, in which data of risk factors of MetS, physical performance tests [resting heart rate (HR), chair stand test (CS), chair sit and reach test (CSR), back scratch test (BS), and single leg stand tests (SLS)] and serum samples of 79 centrally obese MetS subjects aged 58 ± 8 years (39 subjects received 1-year yoga training and 40 subjects received no training) were retrieved for analyses. β-cell function and insulin resistance were examined by Homeostasis Model Assessment (HOMA). Circulating levels of UnAG, AG, obestatin, GH, and insulin were determined by enzyme-linked immunosorbent assay using fasting serum samples. Generalized estimating equation analysis and Mann–Whitney U-test were used to detect statistically significant differences between groups.

Results: Waist circumference (WC) was significantly decreased after yoga intervention (control: +2%; yoga: -4%). Significant improvements in HR (control: +2%; yoga: -5%), CS (control: -1%; yoga: +24%), CSR left (control: worsen by 0.90 cm; yoga: improved by 4.21 cm), CSR right (control: worsen by 0.75 cm; yoga: improved by 4.28 cm), right side of BS (control: improved by 0.19 cm; yoga: improved by 4.31 cm), SLS left (control: -10%; yoga: +86%), and SLS right (control: -6%; yoga: +47%) were observed after 1-year yoga training. No significant difference was found between the two groups in insulin, HOMA indices, and disposition index. Yoga training significantly increased circulating GH (control: -3%; yoga: +22%), total circulating ghrelin (control: -26%; yoga: +13%), and UnAG (control: -27%; yoga: +14%), whereas decreased AG (control: -7%; yoga: -33%) and obestatin (control: +24%; yoga: -29%).

Conclusion: One-year of yoga training modulated total ghrelin, UnAG, AG, obestatin, and GH while exerting beneficial effects on physical functions and central obesity in adults with MetS. The beneficial effects of yoga may be associated with the alteration of ghrelin gene product and GH.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158302/

 

Improve Diabetes with Meditation

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Improve Diabetes with Meditation

 

By John M. de Castro, Ph.D.

 

“As a therapist who works primarily with people with diabetes, I have found that those who have a deeper understanding of themselves and have the ability to cope well with stressful life events simply live better with diabetes, both in terms of diabetes control and general quality of life.” – Joseph Nelson

 

Diabetes is a major health issue. It is estimated that 30 million people in the United States and nearly 600 million people worldwide have diabetes and the numbers are growing. Diabetes is heavily associated with other diseases such as cardiovascular disease, heart attacks, stroke, blindness, kidney disease, and circulatory problems leading to amputations. As a result, diabetes doubles the risk of death of any cause compared to individuals of the same age without diabetes.

 

Type 2 diabetes is a common and increasingly prevalent illness that is largely preventable. One of the reasons for the increasing incidence of Type 2 Diabetes is its association with overweight and obesity which is becoming epidemic in the industrialized world. A leading cause of this is a sedentary life style. Unlike Type I Diabetes, Type II does not require insulin injections. Instead, the treatment and prevention of Type 2 Diabetes focuses on diet, exercise, and weight control. Recently, mindfulness practices have been shown to be helpful in managing diabetes. There is a need for further research into this promising approach to the treatment of patients with diabetes.

 

In today’s Research News article “Mind–Body Interactions and Mindfulness Meditation in Diabetes.” (See summary below or view the full text of the study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954593/ ), Priya and Kalra review and summarize the published research literature on the effectiveness of meditation-based practices for patients with diabetes. They report that the research found that meditation produces changes to the brain areas that reduce the physiological and psychological responses to stress and this improves emotion regulation and coping responses to the disease and overall feelings of well-being.

 

They report that in diabetes patients, meditation-based treatments have been found to improve the psychological state of the patients including improved mood and reduced psychological distress, anxiety, and depression and increased self-care behaviors. These treatments also appear to improve the diabetes patient’s physiological state including lower weight and waist circumference, improved glycemic control, and improved cardiovascular health, including blood pressure, heart rate variability, and vascular resistance.

 

Hence, the published research indicates that meditation-based practices are safe and effective treatments for diabetes patients. “To summarise, mindfulness interventions have demonstrated impact on a broad range of outcomes relating to all domains of holistic care in diabetes – biological, psychological and also social” (Priya and Kalra, 2018).

 

So, improve diabetes with meditation.

 

“Exercise trains the body and meditation train the mind. Many people with diabetes find meditation is a good way to reduce stress, lower blood sugar levels, lower blood pressure readings and minimize pain. Regular meditation should become an important part of your diabetes self-management program.” – Roberta Kleinman

 

CMCS – Center for Mindfulness and Contemplative Studies

 

This and other Contemplative Studies posts are also available on Google+ https://plus.google.com/106784388191201299496/posts and on Twitter @MindfulResearch

 

Study Summary

 

Priya, G., & Kalra, S. (2018). Mind–Body Interactions and Mindfulness Meditation in Diabetes. European Endocrinology, 14(1), 35–41. http://doi.org/10.17925/EE.2018.14.1.35

 

Abstract

Diabetes is associated with significant psychological distress. It is, therefore, important to ensure the physical and emotional as well as psychosocial wellbeing of individuals living with diabetes. Meditation-based strategies have been evaluated for their complementary role in several chronic disorders including depression, anxiety, obesity, hypertension, cardiovascular disease and diabetes. The practice of meditation is associated with reduction in stress and negative emotions and improvements in patient attitude, health-related behaviour and coping skills. There is increased parasympathetic activity with reduction in sympathetic vascular tone, stress hormones and inflammatory markers. Additionally, several studies evaluated the role of mindfulness-based stress reduction in diabetic individuals and demonstrated modest improvements in body weight, glycaemic control and blood pressure. Thus, mindfulness meditation-based intervention can lead to improvements across all domains of holistic care – biological, psychological and social. Though most of these studies have been of short duration and included small numbers of patients, meditation strategies can be useful adjunctive techniques to lifestyle modification and pharmacological management of diabetes and help improve patient wellbeing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954593/